Shankar Siva

Feasibility of biology-guided radiotherapy for metastatic renal cell carcinoma driven by PSMA PET imaging

M Gaudreault, D Chang, N Hardcastle, L McIntosh, P Jackson, T Kron, C Udovicich, MS Hofman, S Siva

Journal article  |  2023  |  Clinical and Translational Radiation Oncology

Background: Biology-guided radiotherapy (BgRT) is a novel treatment where the detection of positron emission originating from a vo..

Mid-treatment adaptive planning during thoracic radiation using 68 Ventilation-Perfusion Positron emission tomography.

Nicholas Bucknell, Nicholas Hardcastle, Roshini Gunewardena, Long Nguyen, Jason Callahan, David Ball, Lisa Selbie, Tomas Kron, Guy-Anne Turgeon, Michael S Hofman, Shankar Siva

Journal article  |  2023  |  Clin Transl Radiat Oncol

UNLABELLED: Four-Dimensional Gallium 68 Ventilation-Perfusion Positron Emission Tomography (68Ga-4D-V/Q PET/CT) allows for dynamic..

Prognostic impact of biologically equivalent dose in stereotactic body radiotherapy for renal cancer.

Kevin T Tran, Neil C Chevli, Jay A Messer, Waqar Haque, Andrew M Farach, Raj Satkunasivam, Jun Zhang, Jorge Darcourt, Simon S Lo, Shankar Siva, Edward B Butler, Bin S Teh

Journal article  |  2023  |  Clin Transl Radiat Oncol

PURPOSE /OBJECTIVES MATERIALS/METHODS: The National Cancer Database (NCDB) was queried (2004-2017) for patients with RCC who did n..

Stereotactic body radiation therapy for kidney cancer. Where do we stand?

Paloma Sosa-Fajardo, Jesús M Blanco-Suarez, Álvaro Pineda-Munguía, Luz Rubí-Olea, Paula Peleteiro-Higuero, Pablo Gajate, Juan Zafra-Martín, Shankar Siva, Alberto Bossi, Fernando López-Campos, Felipe Couñago

Journal article  |  2023  |  Int J Urol

At present, surgery is still the gold standard for the local treatment of renal cancer. Nonetheless, in several clinical scenarios..

Review of Prospective Trials Assessing the Role of Stereotactic Body Radiation Therapy for Metastasis-directed Treatment in Oligometastatic Genitourinary Cancers.

Mai Anh Huynh, Chad Tang, Shankar Siva, Alejandro Berlin, Raquibul Hannan, Andrew Warner, Bridget Koontz, Gert De Meeleer, David Palma, Piet Ost, Phuoc T Tran

Journal article  |  2023  |  Eur Urol Oncol

CONTEXT: Emerging evidence supports the use of stereotactic body radiation therapy (SBRT) as metastatic-directed therapy (MDT) for..

Case of the month from the Peter MacCallum Cancer Centre, Melbourne, Australia: combination of stereotactic ablative body radiotherapy and radical nephrectomy for synchronous bilateral primary renal cell carcinoma.

Muhammad Ali, Mathieu Gaudreault, Shankar Siva

Journal article  |  2023  |  BJU Int

Comparison of dual-energy CT with positron emission tomography for lung perfusion imaging in patients with non-small cell lung cancer

Mathieu Gaudreault, James Korte, Nicholas Bucknell, Price Jackson, Pitchaya Sakyanun, Lachlan McIntosh, Beverley Woon, James P Buteau, Michael S Hofman, Tony Mulcahy, Tomas Kron, Shankar Siva, Nicholas Hardcastle

Journal article  |  2023  |  PHYSICS IN MEDICINE AND BIOLOGY

Objective.Functional lung avoidance (FLA) radiotherapy treatment aims to spare lung regions identified as functional from imaging...

An epithelial-to-mesenchymal transition induced extracellular vesicle prognostic signature in non-small cell lung cancer.

Richard J Lobb, Kekoolani S Visan, Li-Ying Wu, Emma L Norris, Marcus L Hastie, Sarah Everitt, Ian A Yang, Rayleen V Bowman, Shankar Siva, Jill E Larsen, Jeffrey J Gorman, Michael MacManus, Antoine Leimgruber, Kwun M Fong, Andreas Möller

Journal article  |  2023  |  Commun Biol

Despite significant therapeutic advances, lung cancer remains the leading cause of cancer-related death worldwide1. Non-small cell..

Osimertinib for EGFR-Mutant Non-Small-Cell Lung Cancer Central Nervous System Metastases: Current Evidence and Future Perspectives on Therapeutic Strategies.

Sanjay Popat, Myung-Ju Ahn, Simon Ekman, Natasha B Leighl, Suresh S Ramalingam, Thanyanan Reungwetwattana, Shankar Siva, Masahiro Tsuboi, Yi-Long Wu, James Chih-Hsin Yang

Journal article  |  2023  |  Target Oncol

Central nervous system (CNS) metastases are common in non-small-cell lung cancer (NSCLC) and associated with poor prognosis and hi..

The Emerging Role of Extracranial Stereotactic Ablative Radiotherapy for Metastatic Renal Cell Carcinoma: A Systematic Review.

Jennifer Le Guevelou, Paul Sargos, Shankar Siva, Guillaume Ploussard, Piet Ost, Silke Gillessen, Thomas Zilli

Journal article  |  2023  |  Eur Urol Focus

CONTEXT: Although the management of metastatic renal cell carcinoma (mRCC) has been revolutionized by the advent of new systemic a..