Marios Koutsakos

The rise and fall of bone marrow plasma cells after influenza vaccination

Marios Koutsakos, Ali H Ellebedy

Journal article  |  2020  |  Immunology & Cell Biology

Viral burden, inflammatory milieu and CD8( )T-cell responses to influenza virus in a second-generation thiazolide (RM-5061) and oseltamivir combination therapy study

Simone Nuessing, Edin Mifsud, Luca Hensen, Marios Koutsakos, Zhongfang Wang, Lukasz Kedzierski, Francesca Mercuri, Jean-Francois Rossignol, Aeron C Hurt, Katherine Kedzierska

Journal article  |  2020  |  Influenza and Other Respiratory Viruses

BACKGROUND: Influenza viruses cause significant morbidity and mortality, especially in young children, elderly, pregnant women and..

Immune profiling of influenza-specific B- and T-cell responses in macaques using flow cytometry-based assays

Marios Koutsakos, Toshiki Sekiya, Brendon Y Chua, Hoang Oanh Nguyen Thi, Adam K Wheatley, Jennifer A Juno, Marumi Ohno, Naoki Nomura, Yuki Ohara, Tomohiro Nishimura, Masafumi Endo, Saori Suzuki, Hirohito Ishigaki, Misako Nakayama, Cong T Nguyen, Yasushi Itoh, Masashi Shingai, Kazumasa Ogasawara, Yoichiro Kino, Stephen J Kent, et al.

Journal article  |  2020  |  Immunology and Cell Biology

Influenza remains a significant global public health burden, despite substantial annual vaccination efforts against circulating vi..

Innate and adaptive immunity toward influenza B viruses

Luca Hensen, Katherine Kedzierska, Marios Koutsakos

Journal article  |  2020  |  Future Microbiology

Despite annual vaccination, influenza B viruses (IBV) cause significant disease with substantial health and socio-economic impacts..

HLA-B*27:05 alters immunodominance hierarchy of universal influenza-specific CD8( )T cells

Sneha Sant, Sergio M Quinones-Parra, Marios Koutsakos, Emma J Grant, Thomas Loudovaris, Stuart I Mannering, Jane Crowe, Carolien E van de Sandt, Guus F Rimmelzwaan, Jamie Rossjohn, Stephanie Gras, Liyen Loh, Thi HO Nguyen, Katherine Kedzierska

Journal article  |  2020  |  PLoS Pathogens

Seasonal influenza virus infections cause 290,000-650,000 deaths annually and severe morbidity in 3-5 million people. CD8+ T-cell ..

A race to determine what drives COVID-19 severity

Marios Koutsakos, Katherine Kedzierska

Journal article  |  2020  |  Nature

Monocyte apoptotic bodies are vehicles for influenza A virus propagation

Georgia K Atkin-Smith, Mubing Duan, Damien J Zanker, Liyen Loh, Thi HO Nguyen, Marios Koutsakos, Tien Nguyen, Xiangrui Jiang, Julio Carrera, Thanh Kha Phan, Chuanxin Liu, Stephanie Paone, Sara Oveissi, Amy L Hodge, Amy A Baxter, Katherine Kedzierska, Jason M Mackenzie, Mark D Hulett, Pamuk Bilsel, Weisan Chen, et al.

Journal article  |  2020  |  Communications Biology

The disassembly of apoptotic cells into small membrane-bound vesicles termed apoptotic bodies (ApoBDs) is a hallmark of apoptosis;..

Generating protective immunity to severe influenza disease in Indigenous Australians

Luca Hensen, Patricia Illing, Louise Rowntree, Jennifer Habel, Nicole Mifsud, Marios Koutsakos, Liyen Loh, Carolien van de Sandt, Andrea Nguyen, Stephanie Gras, Steve Rockman, Adrian Miller, Oanh Nguyen, Bridie Clemens, Steven Tong, Anthony Purcell, Katherine Kedzierska

Conference Proceedings  |  2020  |  JOURNAL OF IMMUNOLOGY

Immune responses to an inactivated influenza vaacine in Indigenous Australians

Luca Hensen, Louise Rowntree, Timon Damelang, Amy Chung, Adam Wheatley, Maria Auladell, Marios Koutsakos, Nguyen Oanh, Liyen Loh, Malet Aban, Aeron Hurt, Stephen Kent, Katie Flanagan, Magdalena Plebanski, Jane Nelson, Anngie Everitt, Adrian Miller, Jane Davies, Steven Tong, Katherine Kedzierska

Conference Proceedings  |  2020  |  JOURNAL OF IMMUNOLOGY

The ABC of Major Histocompatibility Complexes and T Cell Receptors in Health and Disease

Katherine Kedzierska, Marios Koutsakos

Journal article  |  2020  |  Viral Immunology

A seminal discovery of major histocompatibility complex (MHC) restriction in T cell recognition by Peter Doherty and Rolf Zinkerna..