Jennifer Flegg

Revisiting the Natural History of Pulmonary Tuberculosis: A Bayesian Estimation of Natural Recovery and Mortality Rates.

Romain Ragonnet, Jennifer A Flegg, Samuel L Brilleman, Edine W Tiemersma, Yayehirad A Melsew, Emma S McBryde, James M Trauer

Journal article  |  2021  |  Clin Infect Dis

BACKGROUND: Tuberculosis (TB) natural history remains poorly characterized, and new investigations are impossible as it would be u..

Antibody Dynamics for Plasmodium vivax Malaria: A Mathematical Model.

Somya Mehra, James M McCaw, Mark B Flegg, Peter G Taylor, Jennifer A Flegg

Journal article  |  2021  |  Bulletin of Mathematical Biology

Malaria is a mosquito-borne disease that, despite intensive control and mitigation initiatives, continues to pose an enormous publ..

Numerical Solution of a Two Dimensional Tumour Growth Model with Moving Boundary

J Droniou, JA Flegg, GC Remesan

Journal article  |  2020  |  Journal of Scientific Computing

We consider a biphasic continuum model for avascular tumour growth in two spatial dimensions, in which a cell phase and a fluid ph..

Mathematical Modeling Can Advance Wound Healing Research

Shakti N Menon, Jennifer A Flegg

Journal article  |  2020  |  ADVANCES IN WOUND CARE

Significance: For over 30 years, there has been sustained interest in the development of mathematical models for investigating the..

Influencing public health policy with data-informed mathematical models of infectious diseases: Recent developments and new challenges

Amani Alahmadi, Sarah Belet, Andrew Black, Deborah Cromer, Jennifer A Flegg, Thomas House, Pavithra Jayasundara, Jonathan M Keith, James M McCaw, Robert Moss, Joshua Ross, Freya M Shearer, Thein Than Tun Sai, James Walker, Lisa White, Jason M Whyte, Ada WC Yan, Alexander E Zarebski

Journal article  |  2020  |  EPIDEMICS

Modern data and computational resources, coupled with algorithmic and theoretical advances to exploit these, allow disease dynamic..

First-year and final-year undergraduate students' perceptions of university mathematics departments

Jennifer Hall, Travis Robinson, Jennifer Flegg, Jane Wilkinson

Journal article  |  2020  |  MATHEMATICS EDUCATION RESEARCH JOURNAL

In many countries, concerns have been raised regarding the lack of participation of students in mathematics at the university leve..

Malaria Parasite Clearance: What Are We Really Measuring?

David S Khoury, Sophie G Zaloumis, Matthew J Grigg, Ashraful Haque, Miles P Davenport

Journal article  |  2020  |  TRENDS IN PARASITOLOGY

Antimalarial drugs are vital for treating malaria and controlling transmission. Measuring drug efficacy in the field requires larg..

Parameter estimation for a point-source diffusion-decay morphogen model

Mark B Flegg, Mario A Munoz, Kate Smith-Miles, Wai Shan Yuen, Jennifer A Flegg, John G Carroll

Journal article  |  2020  |  JOURNAL OF MATHEMATICAL BIOLOGY

In this paper we present a novel method for finding unknown parameters for an unknown morphogen. We postulate the existence of an ..

A comparison of approximate versus exact techniques for Bayesian parameter inference in nonlinear ordinary differential equation models

Amani A Alahmadi, Jennifer A Flegg, Davis G Cochrane, Christopher C Drovandi, Jonathan M Keith

Journal article  |  2020  |  ROYAL SOCIETY OPEN SCIENCE

The behaviour of many processes in science and engineering can be accurately described by dynamical system models consisting of a ..

An Activation-Clearance Model for Plasmodium vivax Malaria

Somya Mehra, James M McCaw, Mark B Flegg, Peter G Taylor, Jennifer A Flegg

Journal article  |  2020  |  Bulletin of Mathematical Biology

Malaria is an infectious disease with an immense global health burden. Plasmodium vivax is the most geographically widespread spec..