Alexis Gonzalez

Colonization and metabolite profiles of homologous, heterologous and experimentally evolved algal symbionts in the sea anemone Exaiptasia diaphana

Sarah Jane Tsang Min Ching, Wing Yan Chan, Alexis Perez-Gonzalez, Katie E Hillyer, Patrick Buerger, Madeleine JH van Oppen

Journal article  |  2022  |  ISME Communications

AbstractThe sea anemone, Exaiptasia diaphana, is a model of coral-dinoflagellate (Symbiodiniaceae) symbiosis. However, little is k..

Lack of evidence for the oxidative stress theory of bleaching in the sea anemone, Exaiptasia diaphana, under elevated temperature

AM Dungan, J Maire, A Perez-Gonzalez, LL Blackall, MJH van Oppen

Journal article  |  2022  |  Coral Reefs

To survive in nutrient-poor waters corals rely on a symbiotic association with intracellular microalgae. However, increased sea te..

Unlocking autofluorescence in the era of full spectrum analysis: Implications for immunophenotype discovery projects

Vanta J Jameson, Tina Luke, Yuting Yan, Angela Hind, Maximilien Evrard, Kevin Man, Laura K Mackay, Axel Kallies, Jose A Villadangos, Hamish EG McWilliam, Alexis Perez-Gonzalez

Journal article  |  2022  |  CYTOMETRY PART A

Understanding the complex elements affecting signal resolution in cytometry is key for quality experimental design and data. In th..

Intracellular bacteria are common and taxonomically diverse in cultured and in hospite algal endosymbionts of coral reefs (Feb, 10.1038/ s41396-021-00902-4, 2021)

Justin Maire, Sam K Girvan, Sophie E Barkla, Alexis Perez-Gonzalez, David J Suggett, Linda L Blackall, Madeleine JH van Oppen

Journal article  |  2021  |  ISME JOURNAL

A Correction to this paper has been published: https://doi.org/10.1038/s41396-021-00970-6

Intracellular bacteria are common and taxonomically diverse in cultured and in hospite algal endosymbionts of coral reefs

Justin Maire, Sam K Girvan, Sophie E Barkla, Alexis Perez-Gonzalez, David J Suggett, Linda L Blackall, Madeleine JH van Oppen

Journal article  |  2021  |  ISME JOURNAL

Corals house a variety of microorganisms which they depend on for their survival, including endosymbiotic dinoflagellates (Symbiod..

Hierarchical modelling of immunoglobulin coated bacteria in dogs with chronic enteropathy shows reduction in coating with disease remission but marked inter-individual and treatment-response variability

Lina Maria Martinez-Lopez, Alexis Perez-Gonzalez, Elizabeth Ann Washington, Andrew P Woodward, Alexandra Jazmin Roth-Schulze, Julien RS Dandrieux, Thurid Johnstone, Nathalee Prakash, Aaron Jex, Caroline Mansfield

Journal article  |  2021  |  PLOS ONE

Chronic enteropathies are a common problem in dogs, but many aspects of the pathogenesis remain unknown, making the therapeutic ap..

Outer Membrane Vesicles Prime and Activate Macrophage Inflammasomes and Cytokine Secretion In Vitro and In Vivo

Jessica D Cecil, Neil M O'Brien-Simpson, Jason C Lenzo, James A Holden, William Singleton, Alexis Perez-Gonzalez, Ashley Mansell, Eric C Reynolds

Journal article  |  2017  |  FRONTIERS IN IMMUNOLOGY

Outer membrane vesicles (OMVs) are proteoliposomes blebbed from the surface of Gram-negative bacteria. Chronic periodontitis is as..

Rmax: A systematic approach to evaluate instrument sort performance using center stream catch

Andrew Riddell, Rui Gardner, Alexis Perez-Gonzalez, Telma Lopes, Lola Martinez

Journal article  |  2015  |  METHODS

Sorting performance can be evaluated with regard to Purity, Yield and/or Recovery of the sorted fraction. Purity is a check on the..

Comparative assessment of fluorescent transgene methods for quantitative imaging in human cells

Robert Mahen, Birgit Koch, Malte Wachsmuth, Antonio Z Politi, Alexis Perez-Gonzalez, Julia Mergenthaler, Yin Cai, Jan Ellenberg

Journal article  |  2014  |  MOLECULAR BIOLOGY OF THE CELL

Fluorescence tagging of proteins is a widely used tool to study protein function and dynamics in live cells. However, the extent t..

Sequencing of a Patient with Balanced Chromosome Abnormalities and Neurodevelopmental Disease Identifies Disruption of Multiple High Risk Loci by Structural Variation

Jonathon Blake, Andrew Riddell, Susanne Theiss, Alexis Perez Gonzalez, Bettina Haase, Anna Jauch, Johannes WG Janssen, David Ibberson, Dinko Pavlinic, Ute Moog, Vladimir Benes, Heiko Runz

Journal article  |  2014  |  PLOS ONE

Balanced chromosome abnormalities (BCAs) occur at a high frequency in healthy and diseased individuals, but cost-efficient strateg..