Alexis Gonzalez

Intracellular bacteria are common and taxonomically diverse in cultured and in hospite algal endosymbionts of coral reefs (Feb, 10.1038/ s41396-021-00902-4, 2021)

Justin Maire, Sam K Girvan, Sophie E Barkla, Alexis Perez-Gonzalez, David J Suggett, Linda L Blackall, Madeleine JH van Oppen

Journal article  |  2021  |  ISME JOURNAL

A Correction to this paper has been published: https://doi.org/10.1038/s41396-021-00970-6

Intracellular bacteria are common and taxonomically diverse in cultured and in hospite algal endosymbionts of coral reefs

Justin Maire, Sam K Girvan, Sophie E Barkla, Alexis Perez-Gonzalez, David J Suggett, Linda L Blackall, Madeleine JH van Oppen

Journal article  |  2021  |  ISME JOURNAL

Corals house a variety of microorganisms which they depend on for their survival, including endosymbiotic dinoflagellates (Symbiod..

Hierarchical modelling of immunoglobulin coated bacteria in dogs with chronic enteropathy shows reduction in coating with disease remission but marked inter-individual and treatment-response variability

Lina Maria Martinez-Lopez, Alexis Perez-Gonzalez, Elizabeth Ann Washington, Andrew P Woodward, Alexandra Jazmin Roth-Schulze, Julien RS Dandrieux, Thurid Johnstone, Nathalee Prakash, Aaron Jex, Caroline Mansfield

Journal article  |  2021  |  PLOS ONE

Chronic enteropathies are a common problem in dogs, but many aspects of the pathogenesis remain unknown, making the therapeutic ap..

Outer Membrane Vesicles Prime and Activate Macrophage Inflammasomes and Cytokine Secretion In Vitro and In Vivo

Jessica D Cecil, Neil M O'Brien-Simpson, Jason C Lenzo, James A Holden, William Singleton, Alexis Perez-Gonzalez, Ashley Mansell, Eric C Reynolds

Journal article  |  2017  |  FRONTIERS IN IMMUNOLOGY

Outer membrane vesicles (OMVs) are proteoliposomes blebbed from the surface of Gram-negative bacteria. Chronic periodontitis is as..

Rmax: A systematic approach to evaluate instrument sort performance using center stream catch

Andrew Riddell, Rui Gardner, Alexis Perez-Gonzalez, Telma Lopes, Lola Martinez

Journal article  |  2015  |  METHODS

Sorting performance can be evaluated with regard to Purity, Yield and/or Recovery of the sorted fraction. Purity is a check on the..

Comparative assessment of fluorescent transgene methods for quantitative imaging in human cells

Robert Mahen, Birgit Koch, Malte Wachsmuth, Antonio Z Politi, Alexis Perez-Gonzalez, Julia Mergenthaler, Yin Cai, Jan Ellenberg

Journal article  |  2014  |  MOLECULAR BIOLOGY OF THE CELL

Fluorescence tagging of proteins is a widely used tool to study protein function and dynamics in live cells. However, the extent t..

Sequencing of a Patient with Balanced Chromosome Abnormalities and Neurodevelopmental Disease Identifies Disruption of Multiple High Risk Loci by Structural Variation

Jonathon Blake, Andrew Riddell, Susanne Theiss, Alexis Perez Gonzalez, Bettina Haase, Anna Jauch, Johannes WG Janssen, David Ibberson, Dinko Pavlinic, Ute Moog, Vladimir Benes, Heiko Runz

Journal article  |  2014  |  PLOS ONE

Balanced chromosome abnormalities (BCAs) occur at a high frequency in healthy and diseased individuals, but cost-efficient strateg..

Cell type-specific chromatin immunoprecipitation from multicellular complex samples using BiTS-ChIP

Stefan Bonn, Robert P Zinzen, Alexis Perez-Gonzalez, Andrew Riddell, Anne-Claude Gavin, Eileen EM Furlong

Journal article  |  2012  |  NATURE PROTOCOLS

This protocol describes the batch isolation of tissue-specific chromatin for immunoprecipitation (BiTS-ChIP) for analysis of histo..

Tissue-specific analysis of chromatin state identifies temporal signatures of enhancer activity during embryonic development

Stefan Bonn, Robert P Zinzen, Charles Girardot, E Hilary Gustafson, Alexis Perez-Gonzalez, Nicolas Delhomme, Yad Ghavi-Helm, Bartek Wilczynski, Andrew Riddell, Eileen EM Furlong

Journal article  |  2012  |  NATURE GENETICS

Chromatin modifications are associated with many aspects of gene expression, yet their role in cellular transitions during develop..

Regulatory T cells Contribute to Diabetes Protection in Lipopolysaccharide-Treated Non-Obese Diabetic Mice

I Caramalho, L Rodrigues-Duarte, A Perez, S Zelenay, C Penha-Goncalves, J Demengeot

Journal article  |  2011  |  SCANDINAVIAN JOURNAL OF IMMUNOLOGY

It is well established that viral, parasitic or bacterial infections can prevent type 1 diabetes (T1D) occurrence in non-obese dia..