Karen Dwyer

Clinical Significance of Alloantibodies in Hand Transplantation: A Multicenter Study.

Erik Berglund, Mette Andersen Ljungdahl, Darko Bogdanović, David Berglund, Jonas Wadström, Jan Kowalski, Gerald Brandacher, Dorota Kamińska, Christina L Kaufman, Simon G Talbot, Kodi Azari, Luis Landin, Christoph Höhnke, Karen M Dwyer, Pedro C Cavadas, Alessandro Thione, Brendan Clarke, Simon Kay, Dan Wilks, Subramania Iyer, et al.

Journal article  |  2019  |  Transplantation

BACKGROUND: Donor-specific antibodies (DSAs) have a strong negative correlation with long-term survival in solid organ transplanta..

Real pain in the neck: giant cell arteritis presenting with non-necrotising fasciitis and fever.

Karen M Dwyer, Alex Tai, Paul Smith, Rachelle Buchbinder

Journal article  |  2019  |  Internal Medicine Journal

THE IDENTIFICATION OF POTENTIAL BIOMARKERS OF CHRONIC KIDNEY DISEASE IN INDIVIDUALS WITH DIABETES

Ashani Lecamwasam, Alexandra Sexton-Oates, Jake Carmody, Elif IEkinci, Karen M Dwyer, Richard Saffery

Conference Proceedings  |  2019  |  INTERNAL MEDICINE JOURNAL

High glucose levels affect retinal patterning during zebrafish embryogenesis.

Amitoj Singh, Hozana Andrade Castillo, Julie Brown, Jan Kaslin, Karen M Dwyer, Yann Gibert

Journal article  |  2019  |  Scientific Reports

Maternal hyperglycaemia has a profound impact on the developing foetus and increases the risk of developing abnormalities like obe..

International vascularised composite allotransplantation activity: implications for Australia.

Karen M Dwyer, James D Burt, Tim Bennett

Journal article  |  2019  |  Medical Journal of Australia

In vivo endogenous proteolysis yielding beta-casein derived bioactive beta-casomorphin peptides in human breast milk for infant nutrition.

Ashwantha Kumar Enjapoori, Sonja Kukuljan, Karen M Dwyer, Julie A Sharp

Journal article  |  2019  |  Nutrition

Objective Beta-casein is a major protein in breast milk and an important source for several bioactive peptides that are encrypted ..

Bone health in chronic kidney disease-mineral and bone disorder: a clinical case seminar and update

Jasna Aleksova, Kong W Ng, Caroline Jung, Howard Zeimer, Karen M Dwyer, Frances Milat, Richard J MacIsaac

Journal article  |  2018  |  Internal Medicine Journal

The adenosine, adrenergic and opioid pathways in the regulation of insulin secretion, beta cell proliferation and regeneration.

Amitoj Singh, Yann Gibert, Karen M Dwyer

Journal article  |  2018  |  Pancreatology

Insulin, a key hormone produced by pancreatic beta cells precisely regulates glucose metabolism in vertebrates. In type 1 diabetes..

Dietary Cows' Milk Protein A1 Beta-Casein Increases the Incidence of T1D in NOD Mice

Joanne SJ Chia, Jennifer L McRae, Ashwantha Kumar Enjapoori, Christophe M Lefevre, Sonja Kukuljan, Karen M Dwyer

Journal article  |  2018  |  Nutrients

CD39-adenosinergic axis in renal pathophysiology and therapeutics.

Bellamkonda K Kishore, Simon C Robson, Karen M Dwyer

Journal article  |  2018  |  Purinergic Signalling

Extracellular ATP interacts with purinergic type 2 (P2) receptors and elicits many crucial biological functions. Extracellular ATP..

CD39 and CD73 activity are protective in a mouse model of antiphospholipid antibody-induced miscarriages

Anushka N Samudra, Karen M Dwyer, Carly Selan, Susanna Freddi, Lisa Murray-Segal, Mandana Nikpour, Michael J Hickey, Karlheinz Peter, Simon C Robson, Maithili Sashindranath, Peter J Cowan, Harshal H Nandurkar

Journal article  |  2018  |  Journal of Autoimmunity

DNA methylation profiling of genomic DNA isolated from urine in diabetic chronic kidney disease: A pilot study

Ashani Lecamwasam, Alexandra Sexton-Oates, Jake Carmody, Elif I Ekinci, Karen M Dwyer, Richard Saffery

Journal article  |  2018  |  PLOS ONE

AMP and adenosine are both ligands for adenosine 2B receptor signaling

Jessica K Holien, Benjamin Seibt, Veena Roberts, Evelyn Salvaris, Michael W Parker, Peter J Cowan, Karen M Dwyer

Journal article  |  2018  |  Bioorganic & Medicinal Chemistry Letters

The threat among us: significance and scale of diabetic chronic kidney disease in Australia

Ashani Lecamwasam, Elif I Ekinci, Richard J MacIsaac, Richard Saffery, Karen M Dwyer

Journal article  |  2017  |  Internal Medicine Journal

Refractory Vascular Rejection in a Hand Allograft in the Presence of Antibodies Against Angiotensin II (Type 1) Receptor

Karen M Dwyer, Robert Carroll, Prue Hill, Samantha Bateman, Chris Baker, Robyn G Langham, Wayne Morrison

Journal article  |  2017  |  Transplantation

Gender Equity in Transplantation: A Report from the Women in Transplantation Workshop of The Transplantation Society of Australia and New Zealand.

Karen M Dwyer, Carolyn J Clark, Kelli MacDonald, Miranda A Paraskeva, Natasha Rogers, Jessica Ryan, Angela C Webster, Germaine Wong

Journal article  |  2017  |  Transplantation

The exponential growth of young talented women choosing science and medicine as their professional career over the past decade is ..

Systematic Review of the Gastrointestinal Effects of A1 Compared with A2 β-Casein.

Simon Brooke-Taylor, Karen Dwyer, Keith Woodford, Natalya Kost

Journal article  |  2017  |  Advances in Nutrition: An International Review Journal

This is the first systematic review, to our knowledge, of published studies investigating the gastrointestinal effects of A1-type ..

Diabetes Mellitus Following Renal Transplantation: Clinical and Pharmacological Considerations for the Elderly Patient

David Langsford, Adam Steinberg, Karen M Dwyer

Journal article  |  2017  |  Drugs & Aging

The Differential Effect of Apyrase Treatment and hCD39 Overexpression on Chronic Renal Fibrosis After Ischemia-Reperfusion Injury

Veena Roberts, Duncan J Campbell, Bo Lu, Joanne Chia, Peter J Cowan, Karen M Dwyer

Journal article  |  2017  |  Transplantation

Evaluation of CD4( )CD25( /-)CD39( ) T-cell populations in peripheral blood of patients following kidney transplantation and during acute allograft rejection

Jennifer L McRae, Joanne SJ Chia, Sandra A Pommey, Karen M Dwyer

Journal article  |  2017  |  Nephrology

Overexpression of Human CD55 and CD59 or Treatment with Human CD55 Protects against Renal Ischemia-Reperfusion Injury in Mice

Anjan K Bongoni, Bo Lu, Evelyn J Salvaris, Veena Roberts, Doreen Fang, Jennifer L Mcrae, Nella Fisicaro, Karen M Dwyer, Peter J Cowan

Journal article  |  2017  |  The Journal of Immunology

Development of a novel strategy to target CD39 antithrombotic activity to the endothelial-platelet microenvironment in kidney ischemia-reperfusion injury

Maithili Sashindranath, Karen M Dwyer, Shala Dezfouli, Carly Selan, Sandra Crikis, Bo Lu, Yuping Yuan, Michael J Hickey, Karlheinz Peter, Simon C Robson, Peter J Cowan, Harshal H Nandurkar

Journal article  |  2017  |  Purinergic Signalling

A1 beta-casein milk protein and other environmental pre-disposing factors for type 1 diabetes

JSJ Chia, JL McRae, S Kukuljan, K Woodford, RB Elliott, B Swinburn, KM Dwyer

Journal article  |  2017  |  Nutrition & Diabetes

Mineral adaptations following kidney transplantation

Sven-Jean Tan, Amy Crosthwaite, David Langsford, Varuni Obeysekere, Frank L Ierino, Matthew A Roberts, Peter D Hughes, Tim D Hewitson, Karen M Dwyer, Nigel D Toussaint

Journal article  |  2017  |  Transplant International

CD39 overexpression does not attenuate renal fibrosis in the unilateral ureteric obstructive model of chronic kidney disease

Veena Roberts, B Lu, J Chia, PJ Cowan, KM Dwyer

Journal article  |  2016  |  Purinergic Signalling

A Prospective Study of Renal Transplant Recipients: A Fall in Insulin Secretion Underpins Dysglycemia After Renal Transplantation

David Langsford, Varuni Obeyesekere, Sara Vogrin, Jessie Teng, Richard J MacIsaac, Glenn Ward, Frank Alford, Karen M Dwyer

Journal article  |  2016  |  Transplantation Direct

Role of the CD39/CD73 Purinergic Pathway in Modulating Arterial Thrombosis in Mice

Roman Covarrubias, Elena Chepurko, Adam Reynolds, Zachary M Huttinger, Ryan Huttinger, Katherine Stanfill, Debra G Wheeler, Tatiana Novitskaya, Simon C Robson, Karen M Dwyer, Peter J Cowan, Richard J Gumina

Journal article  |  2016  |  Arteriosclerosis, Thrombosis, and Vascular Biology

A prospective study of renal transplant recipients: the interrelationship between insulin secretion and sensitivity underpins dysglycemia post following renal transplantation

Karen M Dwyer, David Langsford, Varuni Obeyesekere, Jessie Teng, Sara Vogrin, Richard MacIsaac, Glenn Ward, Frank Alford

Conference Proceedings  |  2016  |  TRANSPLANTATION

PLA2R and membranous nephropathy: A 3year prospective Australian study

Prue A Hill, Jennifer L McRae, Karen M Dwyer

Journal article  |  2016  |  Nephrology

Impaired natriuretic response to high-NaCl diet plus aldosterone infusion in mice overexpressing human CD39, an ectonucleotidase (NTPDase1)

Yue Zhang, Simon C Robson, Kaiya L Morris, Kristina M Heiney, Karen M Dwyer, Bellamkonda K Kishore, Carolyn M Ecelbarger

Journal article  |  2015  |  American Journal of Physiology-Renal Physiology

Galactose therapy reduces proteinuria in patients with recurrent focal segmental glomerulosclerosis after kidney transplantation

Kate Robson, Prudence Hill, David Langsford, Karen Dwyer, David Goodman, Robyn Langham

Journal article  |  2015  |  Nephrology

The shifting paradigm of albuminuria in diabetic kidney disease

AK Watts, KM Dwyer, EI Ekinci, G Jerums, RJ MacIsaac

Journal article  |  2015  |  Medicine Today

Adenosine Receptor Expression in the Development of Renal Fibrosis Following Ischemic Injury

V Roberts, B Lu, KM Dwyer, PJ Cowan

Journal article  |  2014  |  Transplantation Proceedings

The role of adenosine receptors A(2A) and A(2B) signaling in renal fibrosis

Veena S Roberts, Peter J Cowan, Stephen I Alexander, Simon C Robson, Karen M Dwyer

Journal article  |  2014  |  Kidney International

Spectrum of renal disease in diabetes

Jessie Teng, Karen M Dwyer, Prue Hill, Emily See, Elif I Ekinci, George Jerums, Richard J Macisaac

Journal article  |  2014  |  Nephrology

Recurrent Mycobacterium haemophilum in a renal transplant recipient

Kathryn Ducharlet, Caitlin Murphy, Sven-Jean Tan, Karen M Dwyer, David Goodman, Craig Aboltins, John R Daffy, Robyn G Langham

Journal article  |  2014  |  Nephrology

The role of ectonucleotidases CD39 and CD73 and adenosine signaling in solid organ transplantation

Veena Roberts, John Stagg, Karen M Dwyer

Journal article  |  2014  |  Frontiers in Immunology

Differential Migration of Passenger Leukocytes and Rapid Deletion of Naive Alloreactive CD8 T Cells After Mouse Liver Transplantation

Szun S Tay, Bo Lu, Fred Sierro, Volker Benseler, Claire M McGuffog, G Alex Bishop, Peter J Cowan, Geoffrey W McCaughan, Karen M Dwyer, David G Bowen, Patrick Bertolino

Journal article  |  2013  |  Liver Transplantation

Blockade of A(2A) receptors potently suppresses the metastasis of CD73( ) tumors

Paul A Beavis, Upulie Divisekera, Christophe Paget, Melvyn T Chow, Liza B John, Christel Devaud, Karen Dwyer, John Stagg, Mark J Smyth, Phillip K Darcy

Journal article  |  2013  |  Proceedings of the National Academy of Sciences of the United States of America

AMPK couples plasma renin to cellular metabolism by phosphorylation of ACC1

Scott A Fraser, Suet-Wan Choy, Nuria M Pastor-Soler, Hui Li, Matthew RP Davies, Natasha Cook, Marina Katerelos, Peter F Mount, Kurt Gleich, Jennifer L McRae, Karen M Dwyer, Bryce JW van Denderen, Kenneth R Hallows, Bruce E Kemp, David A Power

Journal article  |  2013  |  American Journal of Physiology: Renal Physiology

First hand transplant procedure in Australia: outcome at 2 years

Karen M Dwyer, Angela R Webb, Hayley S Furniss, Katie E Anjou, Josephine M Gibbs-Dwyer, David B McCombe, Damien G Grinsell, Gillian F Dickinson, Richard A Williams, Prudence A Russell, David A Scott, Christopher Baker, Simon J Vogrin, Robyn G Langham, Helen I Opdam, Wayne A Morrison

Journal article  |  2013  |  Medical Journal of Australia

Adenosine generation protects in a murine model of antiphospholipid antibody-induced miscarriages

H Nandurkar, A Samudra, A Sharma, XM Zhang, C Selan, K Dwyer, S Robson, A D'Apice, P Cowan

Conference Proceedings  |  2013  |  Journal of Thrombosis and Haemostasis

The CD39-adenosinergic axis in the pathogenesis of renal ischemia-reperfusion injury

Veena Roberts, Bo Lu, Siddharth Rajakumar, Peter J Cowan, Karen M Dwyer

Journal article  |  2013  |  Journal of Biomedicine and Biotechnology

The Protective Effects of CD39 Overexpression in Multiple Low-Dose Streptozotocin-Induced Diabetes in Mice

Joanne SJ Chia, Jennifer L McRae, Helen E Thomas, Stacey Fynch, Lorraine Elkerbout, Prue Hill, Lisa Murray-Segal, Simon C Robson, Jiang-Fan Chen, Anthony JF d'Apice, Peter J Cowan, Karen M Dwyer

Journal article  |  2013  |  Diabetes

Overexpression of CD39 protects in a mouse model of preeclampsia

Jennifer L McRae, Prudence A Russell, Joanne SJ Chia, Karen M Dwyer

Journal article  |  2013  |  Nephrology

Liver grafts from CD39-overexpressing rodents are protected from ischemia reperfusion injury due to reduced numbers of resident CD4( ) T cells

Sandra Pommey, Bo Lu, Jennifer McRae, John Stagg, Prue Hill, Evelyn Salvaris, Simon C Robson, Anthony JF d'Apice, Peter J Cowan, Karen M Dwyer

Journal article  |  2013  |  Hepatology

Liver grafts from CD39-overexpressing rodents are protected from ischemia reperfusion injury due to reduced numbers of resident CD4 T cells

S POMMEY, B Lu, J Mcrae, J Stagg, PA Hill, E Salvaris, SC Robson, AJ D'Apice, PJ Cowan, KM Dwyer

Journal article  |  2013  |  Hepatology

Regulatory T cells participate in CD39-mediated protection from renal injury

Yuan Min Wang, Jennifer L McRae, Simon C Robson, Peter J Cowan, Geoff Yu Zhang, Min Hu, Tania Polhill, Yiping Wang, Guoping Zheng, Ya Wang, Vincent WS Lee, Robert J Unwin, David CH Harris, Karen M Dwyer, Stephen I Alexander

Journal article  |  2012  |  European Journal of Immunology

Cardiac-Specific Ectonucleoside Triphosphate Diphosphohydrolase 1 Overexpression Affords Protection from Myocardial Infarction and Reperfusion Injury

Zhaobin Xu, Debra G Wheeler, Shouvik D Mahamud, Karen M Dwyer, Simon C Robson, Peter J Cowan, Anthony J d'Apice, Richard J Gumina

Conference Proceedings  |  2012  |  CIRCULATION RESEARCH

Hypertensive crisis precipitated by insulin-induced hypoglycemia with end-stage renal failure

L Spain, P Iser, A Steinberg, KM Dwyer

Journal article  |  2012  |  Clinical Kidney Journal

Defective renal water handling in transgenic mice over-expressing human CD39/NTPDase1

Yue Zhang, Kaiya L Morris, Shannon K Sparrow, Karen M Dwyer, Keiichi Enjyoji, Simon C Robson, Bellamkonda K Kishore

Journal article  |  2012  |  American Journal of Physiology: Renal Physiology

Serum sickness following rabbit anti-thymocyte globulin for acute vascular renal allograft rejection

J Teng, XN Hoo, SJ Tan, K Dwyer

Journal article  |  2012  |  Clinical Kidney Journal

Ectonucleotide Triphosphate Diphosphohydrolase-1 (CD39) Mediates Resistance to Occlusive Arterial Thrombus Formation after Vascular Injury in Mice

Zachary M Huttinger, Michael W Milks, Michael S Nickoli, William L Aurand, Lawrence C Long, Debra G Wheeler, Karen M Dwyer, Anthony JF d'Apice, Simon C Robson, Peter J Cowan, Richard J Gumina

Journal article  |  2012  |  American Journal of Pathology

Transgenic swine: Expression of human CD39 protects against myocardial injury

Debra G Wheeler, Matthew E Joseph, Shouvik D Mahamud, William L Aurand, Peter J Mohler, Vincent J Pompili, Karen M Dwyer, Mark B Nottle, Sharon J Harrison, Anthony JF d'Apice, Simon C Robson, Peter J Cowan, Richard J Gumina

Journal article  |  2012  |  Journal of Molecular and Cellular Cardiology

The Outcome of Renal Ischemia-Reperfusion Injury Is Unchanged in AMPK-beta 1 Deficient Mice

Peter F Mount, Kurt Gleich, Shanna Tam, Scott A Fraser, Suet-Wan Choy, Karen M Dwyer, Bo Lu, Bryce Van denderen, Guenter Fingerle-Rowson, Richard Bucala, Bruce E Kemp, David A Power

Journal article  |  2012  |  PLoS One

Ectonucleotidases in cancer and inflammation.

John Stagg, Linda F Thompson, Karen M Dwyer

Journal article  |  2012  |  Journal of biomedicine & biotechnology

The CD39-Adenosinergic Axis in the Pathogenesis of Immune and Nonimmune Diabetes

Joanne SJ Chia, Jennifer L McRae, Peter J Cowan, Karen M Dwyer

Journal article  |  2012  |  Journal of Biomedicine and Biotechnology

Ectonucleotidases in Cancer and Inflammation

John Stagg, Linda F Thompson, Karen M Dwyer

Journal article  |  2012  |  Journal of Biomedicine and Biotechnology

An interaction between tacrolimus and pristinamycin resulting in an elevated tacrolimus level

JV Tehan, SJ Tan, W Gregg, K Dwyer

Journal article  |  2011  |  Clinical Kidney Journal

Transgenic over expression of ectonucleotide triphosphate diphosphohydrolase-1 protects against murine myocardial ischemic injury

Ming Cai, Zachary M Huttinger, Heng He, Weizhi Zhang, Feng Li, Lauren A Goodman, Debra G Wheeler, Lawrence J Druhan, Jay L Zweier, Karen M Dwyer, Guanglong He, Anthony JF d'Apice, Simon C Robson, Peter J Cowan, Richard J Gumina

Journal article  |  2011  |  Journal of Molecular and Cellular Cardiology

Impact of CD39 and purinergic signalling on the growth and metastasis of colorectal cancer

Beat M Kuenzli, Maria-Isabell Bernlochner, Stephan Rath, Samuel Kaeser, Eva Csizmadia, Keiichi Enjyoji, Peter Cowan, Anthony d'Apice, Karen Dwyer, Robert Rosenberg, Aurel Perren, Helmut Friess, Christoph A Maurer, Simon C Robson

Journal article  |  2011  |  Purinergic Signalling

Antioxidant network expression abrogates oxidative posttranslational modifications in mice

R Mital, W Zhang, M Cai, ZM Huttinger, LA Goodman, DG Wheeler, MT Ziolo, KM Dwyer, AJF d'Apice, JL Zweier, G He, PJ Cowan, RJ Gumina

Journal article  |  2011  |  American Journal of Physiology - Heart and Circulatory Physiology

Variable Impact of CD39 in Experimental Murine Colitis

Beat M Kuenzli, Pascal O Berberat, Karen Dwyer, Silvia Deaglio, Eva Csizmadia, Peter Cowan, Anthony d'Apice, Gregory Moore, Keiichi Enjyoji, Helmut Friess, Simon C Robson

Journal article  |  2011  |  Digestive Diseases and Sciences

Deficiency or Inhibition of CD73 Protects in Mild Kidney Ischemia-Reperfusion Injury

Siddharth V Rajakumar, Bo Lu, Sandra Crikis, Simon C Robson, Anthony JF d'Apice, Peter J Cowan, Karen M Dwyer

Journal article  |  2010  |  Transplantation Reviews

Transgenic Overexpression of CD39 Protects Against Renal Ischemia-Reperfusion and Transplant Vascular Injury

S Crikis, B Lu, LM Murray-Segal, C Selan, SC Robson, AJF d'Apice, HH Nandurkar, PJ Cowan, KM Dwyer

Journal article  |  2010  |  American Journal of Transplantation

Expression of CD39 by Human Peripheral Blood CD4( )CD25( ) T Cells Denotes a Regulatory Memory Phenotype

KM Dwyer, D Hanidziar, P Putheti, PA Hill, S Pommey, JL McRae, A Winterhalter, G Doherty, S Deaglio, M Koulmanda, W Gao, SC Robson, TB Strom

Journal article  |  2010  |  American Journal of Transplantation

Antiinflammatory and Anticoagulant Effects of Transgenic Expression of Human Thrombomodulin in Mice

S Crikis, XM Zhang, S Dezfouli, KM Dwyer, LM Murray-Segal, E Salvaris, C Selan, SC Robson, HH Nandurkar, PJ Cowan, AJF d'Apice

Journal article  |  2010  |  American Journal of Transplantation

Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis

John Stagg, Upulie Divisekera, Nicole McLaughlin, Janelle Sharkey, Sandra Pommey, Delphine Denoyer, Karen M Dwyer, Mark J Smyth

Journal article  |  2010  |  Proceedings of the National Academy of Sciences of the United States of America

Acute kidney injury and proteinuria in a patient with diabetes and a submandibular mass.

Prue Hill, Prue Russell, Christine Sammartino, Katherine Wiggins, Karen Dwyer

Journal article  |  2009  |  American Journal of Kidney Diseases

The Impact of Purinergic Signaling on Renal Ischemia-Reperfusion Injury

Bo Lu, Siddharth V Rajakumar, Simon C Robson, Eddy KF Lee, Sandra Crikis, Anthony JF d'Apice, Peter J Cowan, Karen M Dwyer

Journal article  |  2008  |  Transplantation

Adenosine A2A receptor antagonists: blockade of adenosinergic effects and T regulatory cells.

M Sitkovsky, D Lukashev, S Deaglio, K Dwyer, SC Robson, A Ohta

Conference Proceedings  |  2008  |  British Journal of Pharmacology

The intensity and duration of host responses are determined by protective mechanisms that control tissue injury by dampening down ..

Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression.

Silvia Deaglio, Karen M Dwyer, Wenda Gao, David Friedman, Anny Usheva, Anna Erat, Jiang-Fan Chen, Keiichii Enjyoji, Joel Linden, Mohamed Oukka, Vijay K Kuchroo, Terry B Strom, Simon C Robson

Journal article  |  2007  |  Journal of Experimental Medicine

The study of T regulatory cells (T reg cells) has been limited by the lack of specific surface markers and an inability to define ..

CD39 and control of cellular immune responses

KM Dwyer, S Deaglio, W Gao, D Friedman, TB Strom, SC Robson

Journal article  |  2007  |  Purinergic Signalling

Salutary roles of CD39 in transplantation

KM Dwyer, S Deaglio, S Crikis, W Gao, K Enjyoji, TB Strom, PJ Cowan, AJF d'Apice, SC Robson

Journal article  |  2007  |  Transplantation Reviews

The transgenic expression of human CD39 on murine islets inhibits clotting of human blood

Karen M Dwyer, Tharun B Mysore, Sandra Crikis, Simon C Robson, Harshal Nandurkar, Peter J Cowan, Anthony JF d'Apice

Journal article  |  2006  |  Transplantation

RanBPM associates with CD39 and modulates ecto-nucleotidase activity.

Yan Wu, Xiaofeng Sun, Elzbieta Kaczmarek, Karen M Dwyer, Elisabetta Bianchi, Anny Usheva, Simon C Robson

Journal article  |  2006  |  Biochemical Journal

CD39/ecto-NTPDase 1 (nucleoside triphosphate diphosphohydrolase 1) is an ecto-nucleotidase that influences P2 receptor activation ..

Ecto-nucleotidases of the CD39/NTPDase family modulate platelet activation and thrombus formation: Potential as therapeutic targets.

Ben Atkinson, Karen Dwyer, Keiichi Enjyoji, Simon C Robson

Journal article  |  2006  |  Blood Cells, Molecules, and Diseases

Extracellular nucleotide P2-receptor-mediated effects on platelets, leukocytes and endothelium are modulated by ecto-nucleotidases..

Ectonucleotidases of CD39 family modulate vascular inflammation and thrombosis in transplantation.

Simon C Robson, Yan Wu, Xiaofeng Sun, Christoph Knosalla, Karen Dwyer, Keiichi Enjyoji

Journal article  |  2005  |  Seminars in Thrombosis and Hemostasis

Transplantation results in exposure of the graft vasculature to warm and cold ischemia, followed by perfusion by circulating blood..

Severe chronic renal failure in association with oxycodone addiction: A new form of fibrillary glomerulopathy

P Hill, K Dwyer, T Kay, B Murphy

Journal article  |  2002  |  Human Pathology

Xenotransplantation: past achievements and future promise.

Karen M Dwyer, Peter J Cowan, Anthony JF d'Apice

Journal article  |  2002  |  Heart, Lung & Circulation

Xenotransplantation offers a potential solution to the shortfall in donor organs for human transplantation. This review describes ..

Early recurrence of type 1 membranoproliferative glomerulonephritis following cadaveric renal transplantation.

K Dwyer, P Hill, B Murphy

Journal article  |  2000  |  Australian and New Zealand Journal of Medicine

Chronic intestinal pseudo-obstruction in systemic lupus erythematosus due to intestinal smooth muscle myopathy.

PA Hill, KM Dwyer, DA Power

Journal article  |  2000  |  Lupus

We report the case of a woman with systemic lupus erythematosus initially manifesting with fever, rash and arthritis, and two year..