Karen Dwyer

Gut Microbiome Composition Remains Stable in Individuals with Diabetes-Related Early to Late Stage Chronic Kidney Disease

Ashani Lecamwasam, Tiffanie M Nelson, Leni Rivera, Elif I Ekinci, Richard Saffery, Karen M Dwyer

Journal article  |  2021  |  BIOMEDICINES

(1) Background: Individuals with diabetes and chronic kidney disease display gut dysbiosis when compared to healthy controls. Howe..

DNA methylation profiling identifies epigenetic differences between early versus late stages of diabetic chronic kidney disease.

Ashani Lecamwasam, Boris Novakovic, Braydon Meyer, Elif I Ekinci, Karen M Dwyer, Richard Saffery

Journal article  |  2020  |  Nephrol Dial Transplant

BACKGROUND: We investigated a cross-sectional epigenome-wide association study of patients with early and late diabetes-associated..

CHANGES IN PLASMA METABOLITES IN INDIVIDUALS WITH DIABETES ASSOCIATED CHRONIC KIDNEY DISEASE: A CLOSER LOOK AT LIPID PROFILES AND CARDIOVASCULAR RISK

A Lecamwasam, T Mansell, EI Ekinci, R Saffery, KM Dwyer

Conference Proceedings  |  2020  |  NEPHROLOGY

GUT MICROBIOME COMPOSITION REMAINS STABLE IN INDIVIDUALS WITH DIABETES-RELATED EARLY TO LATE STAGE CHRONIC KIDNEY DISEASE

A Lecamwasam, TM Nelson, L Rivera, EI Ekinci, R Saffery, KM Dwyer

Conference Proceedings  |  2020  |  NEPHROLOGY

DNA METHYLATION PROFILING IDENTIFIES EPIGENETIC DIFFERENCES BETWEEN EARLY VERSUS LATE STAGES OF DIABETIC CHRONIC KIDNEY DISEASE

A Lecamwasam, B Novkovic, B Meyer, EI Ekinci, KM Dwyer, R Saffery

Conference Proceedings  |  2020  |  NEPHROLOGY

Conversion of extracellular ATP into adenosine: a master switch in renal health and disease.

Karen M Dwyer, Bellamkonda K Kishore, Simon C Robson

Journal article  |  2020  |  Nat Rev Nephrol

ATP and its ultimate degradation product adenosine are potent extracellular signalling molecules that elicit a variety of pathophy..

Potential for Novel Biomarkers in Diabetes-Associated Chronic Kidney Disease: Epigenome, Metabolome, and Gut Microbiome

Ashani Lecamwasam, Elif I Ekinci, Richard Saffery, Karen M Dwyer

Journal article  |  2020  |  BIOMEDICINES

Diabetes-associated chronic kidney disease is a pandemic issue. Despite the global increase in the number of individuals with this..

The protective effects of human milk-derived peptides on the pancreatic islet biology.

Amitoj Singh, Ashwantha Kumar Enjapoori, Yann Gibert, Karen M Dwyer

Journal article  |  2020  |  Biol Open

Several epidemiological studies support the protective role of breastfeeding in reducing the risk for type 1 diabetes. Human breas..

Clinical Significance of Alloantibodies in Hand Transplantation: A Multicenter Study.

Erik Berglund, Mette Andersen Ljungdahl, Darko Bogdanović, David Berglund, Jonas Wadström, Jan Kowalski, Gerald Brandacher, Dorota Kamińska, Christina L Kaufman, Simon G Talbot, Kodi Azari, Luis Landin, Christoph Höhnke, Karen M Dwyer, Pedro C Cavadas, Alessandro Thione, Brendan Clarke, Simon Kay, Dan Wilks, Subramania Iyer, et al.

Journal article  |  2019  |  Transplantation

BACKGROUND: Donor-specific antibodies (DSAs) have a strong negative correlation with long-term survival in solid organ transplanta..

MON-292 THE IDENTIFICATION OF POTENTIAL BIOMARKERS OF CHRONIC KIDNEY DISEASE IN INDIVIDUALS WITH DIABETES

A Lecamwasam, E Ekinci, K Dwyer, R Saffery

Journal article  |  2019  |  Kidney International Reports