Isabel Lopez Sanchez

Amyloid Precursor Protein Mediates Neuronal Protection from Rotenone Toxicity (vol 56, pg 5471, 2019)

Kathryn Cimdins, Hayley S Waugh, Vicki Chrysostomou, M Isabel G Lopez Sanchez, Vanessa A Johanssen, Mark J Cook, Jonathan G Crowston, Andrew F Hill, James A Duce, Ashley I Bush, Ian A Trounce

Journal article  |  2019  |  Molecular Neurobiology

Amyloid precursor protein-mediated mitochondrial regulation and Alzheimer's disease

M Isabel G Lopez Sanchez, Peter van Wijngaarden, Ian A Trounce

Journal article  |  2019  |  British Journal of Pharmacology

Despite clear evidence of a neuroprotective physiological role of amyloid precursor protein (APP) and its non-amyloidogenic proces..

Amyloid Precursor Protein Mediates Neuronal Protection from Rotenone Toxicity

Kathryn Cimdins, Hayley S Waugh, Vicki Chrysostomou, M Isabel G Lopez Sanchez, Vanessa A Johannsen, Mark J Cook, Jonathan G Crowston, Andrew F Hill, James A Duce, Ashley I Bush, Ian A Trounce

Journal article  |  2019  |  Molecular Neurobiology

Visual recovery as the target for glaucoma

V Chrysostomou, RJ Hatch, T Colgan, JP Paul, P van Wijngaarden, I Trounce, MIG Lopez Sanchez, K Bell, F Grus, JG Crowston

Journal article  |  2019  |  Der Ophthalmologe

Mitochondrial DNA Variation and Disease Susceptibility in Primary Open-Angle Glaucoma

Larry N Singh, Jonathan G Crowston, M Isabel G Lopez Sanchez, Nicole J Van Bergen, Lisa S Kearns, Alex W Hewitt, Seyhan Yazar, David A Mackey, Douglas C Wallace, Ian A Trounce

Journal article  |  2018  |  Investigative Opthalmology & Visual Science

Longitudinal expression profiling of CD4 and CD8 cells in patients with active to quiescent giant cell arteritis

Elisabeth De Smit, Samuel W Lukowski, Lisa Anderson, Anne Senabouth, Kaisar Dauyey, Sharon Song, Bruce Wyse, Lawrie Wheeler, Christine Y Chen, Khoa Cao, Amy Wong Ten Yuen, Neil Shuey, Linda Clarke, Isabel Lopez Sanchez, Sandy SC Hung, Alice Pebay, David A Mackey, Matthew A Brown, Alex W Hewitt, Joseph E Powell

Journal article  |  2018  |  BMC Medical Genomics

Amyloid precursor protein drives down-regulation of mitochondrial oxidative phosphorylation independent of amyloid beta

M Isabel G Lopez Sanchez, Hayley S Waugh, Andrew Tsatsanis, Bruce X Wong, Jonathan G Crowston, James A Duce, Ian A Trounce

Journal article  |  2017  |  Scientific Reports

LONGITUDINAL EXPRESSION PROFILING OF T LYMPHOCYTES IN PATIENTS WITH ACTIVE TO QUIESCENT GIANT CELL ARTERITIS

Elisabeth De Smit, Linda Clarke, Khoa Ngygen, Neil Shuey, Catherine Hill, Lisa Anderson, David Evans, Matt A Brown, Joseph Powell, Alex W Hewitt

Conference Proceedings  |  2016  |  BMC Medical Genomics

Emerging Mitochondrial Therapeutic Targets in Optic Neuropathies

MIG Lopez Sanchez, JG Crowston, DA Mackey, IA Trounce

Journal article  |  2016  |  Pharmacology & Therapeutics

Loss of mitochondrial DNA-encoded protein ND1 results in disruption of complex I biogenesis during early stages of assembly

Sze Chern Lim, Jana Hroudova, Nicole J Van Bergen, M Isabel G Lopez Sanchez, Ian A Trounce, Matthew McKenzie

Journal article  |  2016  |  The FASEB Journal

Estrogen-Mediated Regulation of Mitochondrial Gene Expression

Maria IG Lopez Sanchez, Anne-Marie J Shearwood, Tiongsun Chia, Stefan MK Davies, Oliver Rackham, Aleksandra Filipovska

Journal article  |  2015  |  Molecular Endocrinology

Capture of Somatic mtDNA Point Mutations with Severe Effects on Oxidative Phosphorylation in Synaptosome Cybrid Clones from Human Brain

Matthew McKenzie, Maria Chiotis, Jana Hroudova, Maria IG Lopez Sanchez, Sze Chern Lim, Mark J Cook, Penny McKelvie, Richard GH Cotton, Michael Murphy, Justin C St John, Ian A Trounce

Journal article  |  2014  |  Human Mutation

MRPS27 is a pentatricopeptide repeat domain protein required for the translation of mitochondrially encoded proteins

Stefan MK Davies, Maria IG Lopez Sanchez, Reena Narsai, Anne-Marie J Shearwood, Muhammad FM Razif, Ian D Small, James Whelan, Oliver Rackham, Aleksandra Filipovska

Journal article  |  2012  |  FEBS Letters

RNA processing in human mitochondria

Maria IG Lopez Sanchez, Tim R Mercer, Stefan MK Davies, Anne-Marie J Shearwood, Karoline KA Nygard, Tara R Richman, John S Mattick, Oliver Rackham, Aleksandra Filipovska

Journal article  |  2011  |  Cell Cycle