Ahmed Al Saedi

Characterization of Skeletal Phenotype and Associated Mechanisms With Chronic Intestinal Inflammation in the Winnie Mouse Model of Spontaneous Chronic Colitis.

Ahmed Al Saedi, Shilpa Sharma, Ebrahim Bani Hassan, Lulu Chen, Ali Ghasem-Zadeh, Majid Hassanzadeganroudsari, Jonathan H Gooi, Rhian Stavely, Rajaraman Eri, Dengshun Miao, Kulmira Nurgali, Gustavo Duque

Journal article  |  2021  |  Inflamm Bowel Dis

BACKGROUND: Osteoporosis is a common extraintestinal manifestation of inflammatory bowel disease (IBD). However, studies have been..

The effect of vitamin D supplementation on circulating osteoprogenitor cells: A pilot randomized controlled trial

Jack Feehan, Elizabeth Degabrielle, Nicholas Tripodi, Ahmed Al Saedi, Sara Vogrin, Gustavo Duque

Journal article  |  2021  |  EXPERIMENTAL GERONTOLOGY

Circulating osteoprogenitor (COP) cells are a relatively newly discovered mesenchymal precursors population in the peripheral bloo..

Targeting intramuscular adipose tissue expansion to preserve contractile function in volumetric muscle loss: A potentially novel therapy?

Ahmed Al Saedi, Gustavo Duque, Nicole Stupka

Journal article  |  2021  |  CURRENT OPINION IN PHARMACOLOGY

In volumetric muscle loss (VML), the severity of trauma exceeds a muscle's regenerative capacity. VML causes permanent functional ..

Uncovering the Bone-Muscle Interaction and Its Implications for the Health and Function of Older Adults (the Wellderly Project): Protocol for a Randomized Controlled Crossover Trial

Cassandra Smith, Xuzhu Lin, David Scott, Tara C Brennan-Speranza, Ahmed Al Saedi, Alba Moreno-Asso, Mary Woessner, Ebrahim Bani Hassan, Nir Eynon, Gustavo Duque, Itamar Levinger

Journal article  |  2021  |  JMIR RESEARCH PROTOCOLS

BACKGROUND: Bone and muscle are closely linked anatomically, biochemically, and metabolically. Acute exercise affects both bone an..

1,25(OH)(2)D-3 ameliorates palmitate-induced lipotoxicity in human primary osteoblasts leading to improved viability and function

Ahmed Al Saedi, Damian E Myers, Nicole Stupka, Gustavo Duque

Journal article  |  2020  |  BONE

Contributing to bone loss with aging is a progressive reduction in osteoblast number and function leading to decreased bone format..

FAT AS A THERAPEUTIC TARGET IN OSTEOSARCOPENIA

G Duque, B Kirk, A Al Saedi

Conference Proceedings  |  2020  |  OSTEOPOROSIS INTERNATIONAL

Differential Effects of Long-Term Caloric Restriction and Dietary Protein Source on Bone and Marrow Fat of the Aging Rat

Gustavo Duque, Ahmed Al Saedi, Daniel Rivas, Stephanie Miard, Guylaine Ferland, Frederic Picard, Pierrette Gaudreau

Journal article  |  2020  |  JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Long-term caloric restriction (CR) has been shown to be beneficial to various tissues and organs. In contrast, CR exerts different..

The Changing Partners of FOXO1 Under High Serotonin Levels in Winnie Mouse Model of Spontaneous Chronic Colitis

Shilpa Sharma, Ahmed Al Saedi, Kulmira Nurgali, Gustavo Duque

Conference Proceedings  |  2020  |  JOURNAL OF BONE AND MINERAL RESEARCH

Blood borne bone: Circulating Osteoprogenitors Associated with Bone and Muscle quality

Jack Feehan, Cassandra Smith, Alexander Tacey, Ahmed Al Saedi, Gustavo Duque, Itamar Levinger

Conference Proceedings  |  2020  |  JOURNAL OF BONE AND MINERAL RESEARCH

Lipid Signaling Mediators regulates myogenesis with ageing

Ahmed Al Saedi, Gustavo Duque, Marco Brotto, Zhiying Wang

Conference Proceedings  |  2020  |  JOURNAL OF BONE AND MINERAL RESEARCH