Gustavo Noffs

Acoustic Speech Analytics Are Predictive of Cerebellar Dysfunction in Multiple Sclerosis

Gustavo Noffs, Frederique MC Boonstra, Thushara Perera, Scott C Kolbe, Jim Stankovich, Helmut Butzkueven, Andrew Evans, Adam P Vogel, Anneke van der Walt

Journal article  |  2020  |  The Cerebellum

Speech production relies on motor control and cognitive processing and is linked to cerebellar function. In diseases where the cer..

OnabotulinumtoxinA treatment for MS-tremor modifies fMRI tremor response in central sensory-motor integration areas

Frederique MC Boonstra, Andrew Evans, Gustavo Noffs, Thushara Perera, Vilija Jokubaitis, Jim Stankovich, Adam P Vogel, Bradford A Moffat, Helmut Butzkueven, Scott C Kolbe, Anneke van der Walt

Journal article  |  2020  |  Multiple Sclerosis and Related Disorders

BACKGROUND: Treatment of tremor in MS is an unmet need. OnabotulinumtoxinA (BoNT-A) has shown promising results; however, little i..

Functional neuroplasticity in response to cerebello-thalamic injury underpins the clinical presentation of tremor in multiple sclerosis.

Frederique Mc Boonstra, Gustavo Noffs, Thushara Perera, Vilija G Jokubaitis, Adam P Vogel, Bradford A Moffat, Helmut Butzkueven, Andrew Evans, Anneke van der Walt, Scott C Kolbe

Journal article  |  2020  |  Multiple Sclerosis Journal

BACKGROUND: Tremor is present in almost half of multiple sclerosis (MS) patients. The lack of understanding of its pathophysiology..

What speech can tell us: A systematic review of dysarthria characteristics in Multiple Sclerosis

Gustavo Noffs, Thushara Perera, Scott C Kolbe, Camille J Shanahan, Frederique MC Boonstra, Andrew Evans, Helmut Butzkueven, Anneke van der Walt, Adam P Vogel

Journal article  |  2018  |  AUTOIMMUNITY REVIEWS