Piers Blombery

Utility of clinical comprehensive genomic characterization for diagnostic categorization in patients presenting with hypocellular bone marrow failure syndromes

Piers Blombery, Lucy C Fox, Georgina L Ryland, Ella R Thompson, Jennifer Lickiss, Michelle McBean, Satwica Yerneni, David Hughes, Anthea Greenway, Francoise Mechinaud, Erica M Wood, Graham J Lieschke, Jeff Szer, Pasquale Barbaro, John Roy, Joel Wight, Elly Lynch, Melissa Martyn, Clara Gaff, David Ritchie

Journal article  |  2021  |  Haematologica: the hematology journal

Bone marrow failure (BMF) related to hypoplasia of haematopoietic elements in the bone marrow is a heterogeneous clinical entity w..

Clonal independence of JAK2 and CALR or MPL mutations in comutated myeloproliferative neoplasms demonstrated by single cell DNA sequencing

Ella R Thompson, Tamia Nguyen, Yamuna Kankanige, Paul Yeh, Michael Ingbritsen, Michelle McBean, Timothy Semple, Gisela Mir Arnau, Kate Burbury, Nora Lee, Amit Khot, David Westerman, Piers Blombery

Journal article  |  2021  |  Haematologica: the hematology journal

Laboratory quality assessment of candidate gene panel testing for acute myeloid leukaemia: a joint ALLG / RCPAQAP initiative.

Greg Corboy, Jad Othman, Linda Lee, Andrew Wei, Adam Ivey, Piers Blombery, Rishu Agarwal, Chun Fong, Anna Brown, Hamish Scott, Carolyn Grove, Alison Louw, Anoop Enjeti, Harry Iland, Cheryl Paul, Stefan Bohlander, Purvi Kakadia, Martin Horan, William Stevenson

Journal article  |  2020  |  Pathology

Accurate classification of acute myeloid leukaemia (AML) has become increasingly reliant on molecular characterisation of this blo..

Acquired Mutations in BAX Confer Resistance to BH3 Mimetics in Acute Myeloid Leukemia

Donia M Moujalled, Fiona C Brown, Giovanna Pomilio, Natasha S Anstee, Veronique Litalien, Ella R Thompson, Thomas Morley, Sarah MacRaild, Chong C Chua, SeBastien Banquet, Maia Chanrion, Ana-Leticia Maragno, Marie Schoumacher, Marco J Herold, Guillaume Lessene, Olivier Geneste, David CS Huang, Andrew W Roberts, Piers Blombery, Andrew Wei

Journal article  |  2020  |  Blood

Background: Recent randomized trials have demonstrated improvements in overall survival (OS) for the BCL-2 inhibito..

A Phase II, Open-Label, Single Arm Trial to Assess the Efficacy and Safety of the Combination of Tisagenlecleucel and Ibrutinib in Mantle Cell Lymphoma (TARMAC)

Adrian Minson, Nada Hamad, Jason P Butler, David Alan Westerman, David Ritchie, Piers Blombery, John F Seymour, Constantine S Tam, Michael Dickinson

Journal article  |  2020  |  Blood

Background Mantle cell lymphoma (MCL) is a clinically and pathogenetically distinct B-cell non-Hodgkin lymphoma tha..

Longitudinal Genomic Characterization Using Cell-Free DNA in Patients with Idiopathic Aplastic Anemia

Georgina L Ryland, Lucy C Fox, Xiangting Chen, Satwica Yerneni, Jeffrey Szer, Ashish Bajel, Robin J Filshie, Sue Morgan, Sarah-Jane Dawson, Piers Blombery

Journal article  |  2020  |  Blood

The molecular profile of clonal hematopoiesis in patients (pts) with idiopathic aplastic anaemia (iAA) has been shown to predict r..

BAX-Mutated Clonal Hematopoiesis in Patients on Long-Term Venetoclax for Relapsed/Refractory Chronic Lymphocytic Leukemia

Piers Blombery, Ella R Thompson, Xiangting Chen, Tamia Nguyen, Mary Ann Anderson, David Alan Westerman, John F Seymour, Constantine S Tam, Michael A Dengler, David CS Huang, Andrew Wei, Andrew W Roberts

Journal article  |  2020  |  Blood

Venetoclax (Ven) is an effective element of treatments for chronic lymphocytic leukemia (CLL) with high response rates observed in..

VARIANTS IN SAMD9 ARE ASSOCIATED WITH PAEDIATRIC FOCAL SEGMENTAL GLOMERULOSCLEROSIS

TA Forbes, C D'Arcy, P Blombery, D Efron, E Wilkins, T Cole, SL Khaw, C Quinlan, SM White

Conference Proceedings  |  2020  |  NEPHROLOGY

Abstract IA44: ctDNA in indolent lymphoid cancers treated with targeted therapies

Constantine S Tam, Piers Blombery

Conference Proceedings  |  2020  |  Oral Presentations - Invited Abstracts

Immune recovery in patients with mantle cell lymphoma receiving long-term ibrutinib and venetoclax combination therapy

Joanne E Davis, Sasanka M Handunnetti, Mandy Ludford-Menting, Chia Sharpe, Piers Blombery, Mary Ann Anderson, Andrew W Roberts, John F Seymour, Constantine S Tam, David S Ritchie, Rachel M Koldej

Journal article  |  2020  |  Blood Advances

Combination venetoclax plus ibrutinib for the treatment of mantle cell lymphoma (MCL) has demonstrated efficacy in the relapsed or..