Jordan Hansford

Survival Benefit for Individuals With Constitutional Mismatch Repair Deficiency Undergoing Surveillance.

Carol Durno, Ayse Bahar Ercan, Vanessa Bianchi, Melissa Edwards, Melyssa Aronson, Melissa Galati, Eshetu G Atenafu, Gadi Abebe-Campino, Abeer Al-Battashi, Musa Alharbi, Vahid Fallah Azad, Hagit N Baris, Donald Basel, Raymond Bedgood, Anne Bendel, Shay Ben-Shachar, Deborah T Blumenthal, Maude Blundell, Miriam Bornhorst, Annika Bronsema, et al.

Journal article  |  2021  |  J Clin Oncol

PURPOSE: Constitutional mismatch repair deficiency syndrome (CMMRD) is a lethal cancer predisposition syndrome characterized by ea..

PATZ1 fusions define a novel molecularly distinct neuroepithelial tumor entity with a broad histological spectrum

Karam T Alhalabi, Damian Stichel, Philipp Sievers, Heike Peterziel, Alexander C Sommerkamp, Dominik Sturm, Andrea Wittmann, Martin Sill, Natalie Jaeger, Pengbo Beck, Kristian W Pajtler, Matija Snuderl, George Jour, Michael Delorenzo, Allison M Martin, Adam Levy, Nagma Dalvi, Jordan R Hansford, Nicholas G Gottardo, Emmanuelle Uro-Coste, et al.

Journal article  |  2021  |  ACTA NEUROPATHOLOGICA

Large-scale molecular profiling studies in recent years have shown that central nervous system (CNS) tumors display a much greater..

Ultra high-risk PFA ependymoma is characterized by loss of chromosome 6q

Lorena Baroni, Lakshmikirupa Sundaresan, Ayala Heled, Hallie Coltin, Kristian W Pajtler, Tong Lin, Thomas E Merchant, Roger McLendon, Claudia Faria, Molly Buntine, Christine L White, Stefan M Pfister, Mark R Gilbert, Terri S Armstrong, Eric Bouffet, Sachin Kumar, Michael D Taylor, Kenneth D Aldape, David W Ellison, Nicholas G Gottardo, et al.

Journal article  |  2021  |  NEURO-ONCOLOGY

BACKGROUND: Within PF-EPN-A, 1q gain is a marker of poor prognosis, however, it is unclear if within PF-EPN-A additional cytogenet..

Systems-Level Change to Alleviate Barriers to Cancer Clinical Trial Access for Adolescents and Young Adults in Australia

Justine A Ellis, Vajiranee S Malalasekera, Christie Allan, Peter F Choong, Jordan R Hansford, Ryan Hehir, Natasha Morello, Sally O'Callaghan, Lisa Orme, Nitya Phillipson, Mark A Rosenthal, Susan Sawyer, Robyn Strong, Leanne Super, Angela Watt, Chris Williams, Anne Woollett, Alexandra Robertson, Jeremy Lewin

Journal article  |  2021  |  JOURNAL OF ADOLESCENT AND YOUNG ADULT ONCOLOGY

Purpose: International data demonstrate association between clinical trial participation and reduced cancer mortality. Adolescents..

Emergence and maintenance of actionable genetic drivers at medulloblastoma relapse.

Stacey Richardson, Rebecca M Hill, Christopher Kui, Janet C Lindsey, Yura Grabovksa, Claire Keeling, Louise Pease, Matthew Bashton, Stephen Crosier, Maria Vinci, Nicolas André, Dominique Figarella-Branger, Jordan R Hansford, Maria Lastowska, Krzysztof Zakrzewski, Mette Jorgensen, Jessica C Pickles, Michael D Taylor, Stefan M Pfister, Stephen B Wharton, et al.

Journal article  |  2021  |  Neuro Oncol

BACKGROUND: 90% of tumors) and established genetic drivers (e.g. SHH/WNT/P53 mutations; 60% of rMB events) were maintained from di..

An unexpected disease course for a patient with diffuse midline glioma

Vajiranee S Malalasekera, Colleen E D'Arcy, Cristina Mignone, Alison C Wray, Javad Nazarian, Jeremy L Freeman, Jordan R Hansford

Journal article  |  2021  |  PEDIATRIC BLOOD & CANCER

Growth hormone and targeted oncological agents: Are we stopping children with brain tumours from reaching their true height potential?

Hannah Walker, Dong Anh Khuong Quang, Martin Campbell, Kanika Bhatia, Molly Williams, Michael Sullivan, David D Eisenstat, Kung-Ting Kao, Jessica Ng, Mary White, Margaret Zacharin, Jordan R Hansford

Journal article  |  2021  |  JOURNAL OF PAEDIATRICS AND CHILD HEALTH

Children with low-grade gliomas have excellent long-term survival outcomes. The development of therapies targeted to the driver mu..

Characteristics of Patients ≥ 10 Years of Age with Diffuse Intrinsic Pontine Glioma: A Report from the International DIPG Registry.

Craig Erker, Adam Lane, Brooklyn Chaney, Sarah Leary, Jane E Minturn, Ute Bartels, Roger J Packer, Kathleen Dorris, Nicholas G Gottardo, Katherine E Warren, Alberto Broniscer, W Kieran Mark, Xiaoting Zhu, Peter White, Phillip Dexheimer, Katie Black, Anthony Asher, Mariko DeWire-Shottmiller, Jordan R Hansford, Sridharan Gururangan, et al.

Journal article  |  2021  |  Neuro Oncol

BACKGROUND: DIPG generally occurs in young school-age children, although can occur in adolescents and young adults. The purpose of..

RARE-07. EFFICACY AND SAFETY OF LAROTRECTINIB IN PEDIATRIC PATIENTS WITH TROPOMYOSIN RECEPTOR KINASE (TRK) FUSION-POSITIVE PRIMARY CENTRAL NERVOUS SYSTEM (CNS) TUMORS

Sébastien Perreault, François Doz, Birgit Geoerger, Karsten Nysom, Ingrid Øra, Valentina Boni, Julia Chisholm, Steven G DuBois, Nicolas U Gerber, Hiroaki Goto, Juneko E Grilley-Olson, Jordan R Hansford, Hyoung Jin Kang, Michael Capra, Johannes H Schulte, Joanna Stefanowicz, Makoto Tahara, David S Ziegler, Ricarda Norenberg, Laura Dima, et al.

Journal article  |  2021  |  Neuro-oncology

Abstract Background NTRK gene fusions are oncogenic drivers in various CNS and non-CNS tumors. Larotrectinib is a highly selective..

EMBR-03. PINEOBLASTOMA: A POOLED OUTCOME STUDY OF NORTH AMERICAN AND AUSTRALIAN THERAPEUTIC DATA

Jordan Hansford, Jie Huang, Andrew Dodgshun, Bryan Li, Eugene Hwang, Sarah Leary, Amar Gajjar, Katja Von Hoff, Raelene Endersby, Olivia Wells, Alison Wray, Rishi Kotecha, David Raleigh, Schuyler Stoller, Sabine Mueller, Steven Schild, Pratiti Bandopadhayay, Maryam Fouladi, Eric Bouffet, Annie Huang, et al.

Journal article  |  2021  |  Neuro-oncology

Abstract Background Pineoblastoma (PB) is a rare embryonal brain tumour most often diagnosed in young children. To date, no clinic..