Brett Pearce

Effect of Intraoperative Low Tidal Volume vs Conventional Tidal Volume on Postoperative Pulmonary Complications in Patients Undergoing Major Surgery A Randomized Clinical Trial

Dharshi Karalapillai, Laurence Weinberg, Philip Peyton, Louise Ellard, Raymond Hu, Brett Pearce, Chong O Tan, David Story, Mark O'Donnell, Patrick Hamilton, Chad Oughton, Jonathan Galtieri, Anthony Wilson, Ary Serpa Neto, Glenn Eastwood, Rinaldo Bellomo, Daryl A Jones

Journal article  |  2020  |  JAMA

Importance: In patients who undergo mechanical ventilation during surgery, the ideal tidal volume is unclear. Objective: To determ..

Intrathecal morphine is associated with reduction in postoperative opioid requirements and improvement in postoperative analgesia in patients undergoing open liver resection

Jefferson Tang, Leonid Churilov, Chong Oon Tan, Raymond Hu, Brett Pearce, Luka Cosic, Christopher Christophi, Laurence Weinberg

Journal article  |  2020  |  BMC Anesthesiology

BACKGROUND: Our study aimed to test the hypothesis that the addition of intrathecal morphine (ITM) results in reduced postoperativ..

Frequency of hyperoxaemia during and after major surgery

Dharshi Karalapillai, Laurence Weinberg, Philip J Peyton, Louise Ellard, Raymond Hu, Brett Pearce, Chong Tan, David Story, Mark O'Donnell, Patrick Hamilton, Chad Oughton, Jonathan Galtieri, Anthony Wilson, Glenn Eastwood, Rinaldo Bellomo, Daryl Jones

Journal article  |  2020  |  Anaesthesia and Intensive Care

The oxygen concentration (FiO2) and arterial oxygen tension (PaO2) delivered in patients undergoing major surgery is poorly unders..

Randomised controlled trial to investigate the relationship between mild hypercapnia and cerebral oxygen saturation in patients undergoing major surgery

Clarence Wong, Leonid Churilov, Dean Cowie, Chong Oon Tan, Raymond Hu, David Tremewen, Brett Pearce, Param Pillai, Dharshi Karalapillai, Rinaldo Bellomo, Laurence Weinberg

Journal article  |  2020  |  BMJ Open

OBJECTIVES: The effects of hypercapnia on regional cerebral oxygen saturation (rSO2) during surgery are unclear. We conducted a ra..

Low tidal volume ventilation during anaesthesia for major surgery: protocol and statistical analysis plan

Dharshi Karalapillai, Laurence Weinberg, Phil Peyton, Louise Ellard, Raymond Hu, Brett Pearce, Chong Tan, David Story, Mark ODonnell, Patrick Hamilton, Chad Oughton, Jonathan Galtieri, Anthony Wilson, Ary Serpa Neto, Glenn Eastwood, Rinaldo Bellomo, Daryl A Jones

Journal article  |  2019  |  Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine

BACKGROUND: Mechanical ventilation is mandatory in patients undergoing general anaesthesia for major surgery. Tidal volumes higher..

Intraoperative TOE guided management of newly diagnosed severe tricuspid regurgitation and pulmonary hypertension during orthotopic liver transplantation: a case report demonstrating the importance of reversibility as a favorable prognostic factor

B Pearce, R Hu, F Desmond, D Banyasz, R Jones, CO Tan

Journal article  |  2019  |  BMC Anesthesiology

High frequency, low background rate extrapleural programmed intermittent bolus ropivacaine provides superior analgesia compared with continuous infusion for acute pain management following thoracic surgery: A retrospective cohort study

B Bishop, B Pearce, L Willshire, M Kilpin, W Howard, L Weinberg, C Tan

Journal article  |  2019  |  Anesthesiology and Pain Medicine

Comparison of the WarmCloud and Bair Hugger Warming Devices for the Prevention of Intraoperative Hypothermia in Patients Undergoing Orthotopic Liver Transplantation: A Randomized Clinical Trial

Brett Pearce, Linda Mattheyse, Louise Ellard, Fiona Desmond, Param Pillai, Laurence Weinberg

Journal article  |  2018  |  Transplantation Direct

Agreement in hemodynamic monitoring during orthotopic liver transplantation: a comparison of FloTrac/Vigileo at two monitoring sites with pulmonary artery catheter thermodilution

Matthew Lee, Laurence Weinberg, Brett Pearce, Nicholas Scurrah, David A Story, Param Pillai, Peter R McCall, Larry P McNicol, Philip J Peyton

Journal article  |  2017  |  Journal of Clinical Monitoring and Computing

Prevention of hypothermia in patients undergoing orthotopic liver transplantation using the humigard (R) open surgery humidification system: a prospective randomized pilot and feasibility clinical trial

Laurence Weinberg, Andrew Huang, Daniel Alban, Robert Jones, David Story, Larry McNicol, Brett Pearce

Journal article  |  2017  |  BMC SURGERY