Tao Wang

Genome-wide exploration reveals distinctive northern and southern variants of Clonorchis sinensis in the Far East

Liina Kinkar, Pasi K Korhonen, Urmas Saarma, Tao Wang, Xing-Quan Zhu, Ivon Harliwong, Bicheng Yang, J Lynn Fink, Daxi Wang, Bill CH Chang, Galina N Chelomina, Anson V Koehler, Neil D Young, Robin B Gasser

Journal article  |  2023  |  MOLECULAR ECOLOGY RESOURCES

Clonorchis sinensis is a carcinogenic liver fluke that causes clonorchiasis-a neglected tropical disease (NTD) affecting ~35 milli..

Haem transporter HRG-1 is essential in the barber's pole worm and an intervention target candidate.

Yi Yang, Jingru Zhou, Fei Wu, Danni Tong, Xueqiu Chen, Shengjun Jiang, Yu Duan, Chaoqun Yao, Tao Wang, Aifang Du, Robin B Gasser, Guangxu Ma

Journal article  |  2023  |  PLoS Pathog

Parasitic roundworms (nematodes) have lost genes involved in the de novo biosynthesis of haem, but have evolved the capacity to ac..

Proteomic analysis of Sarcoptes scabiei reveals that proteins differentially expressed between eggs and female adult stages are involved predominantly in genetic information processing, metabolism and/or host-parasite interactions

Tao A Wang, Robin Gasser, Pasi R Korhonen, Neil D Young, Ching-Seng Ang, Nicholas Williamson, Guangxu Ma, Gangi Samarawickrama, Deepani Fernando, Katja Fischer

Journal article  |  2022  |  PLOS NEGLECTED TROPICAL DISEASES

Presently, there is a dearth of proteomic data for parasitic mites and their relationship with the host animals. Here, using a hig..

Hydra 2022: return of the interactive conference on helminth parasitology after the pandemic

Caitlin M McManus, Tiffany Bouchery, Mona Suleiman, Anna O Kildemoes, Annabel Ferguson, Tao Wang, Conor M Finlay, Ryan Chan, Tess Renahan, Ananya Mukundan, Gyaviira Nkurunungi, Sarah D Bobardt

Journal article  |  2022  |  TRENDS IN PARASITOLOGY

Thermal proteome profiling reveals Haemonchus orphan protein HCO_011565 as a target of the nematocidal small molecule UMW-868

Aya CC Taki, Tao Wang, Nghi NN Nguyen, Ching-Seng Ang, Michael GG Leeming, Shuai Nie, Joseph JJ Byrne, Neil DD Young, Yuanting Zheng, Guangxu Ma, Pasi KK Korhonen, Anson VV Koehler, Nicholas AA Williamson, Andreas Hofmann, Bill CH Chang, Cecile Haeberli, Jennifer Keiser, Abdul Jabbar, Brad EE Sleebs, Robin BB Gasser

Journal article  |  2022  |  FRONTIERS IN PHARMACOLOGY

Parasitic roundworms (nematodes) cause destructive diseases, and immense suffering in humans and other animals around the world. T..

Evidence that Transcriptional Alterations in Sarcoptes scabiei Are under Tight Post-Transcriptional (microRNA) Control

Pasi K Korhonen, Tao Wang, Neil D Young, Gangi R Samarawickrama, Deepani D Fernando, Guangxu Ma, Robin B Gasser, Katja Fischer

Journal article  |  2022  |  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Here, we explored transcriptomic differences among early egg (Ee), late egg (Le) and adult female (Af) stages of the scabies mite,..

The non-glycosylated protein of Toxocara canis MUC-1 interacts with proteins of murine macrophages.

Rongqiong Zhou, Hongguo Jia, Zhendong Du, Aiyun Jiang, Zhenhui Song, Tao Wang, Aifang Du, Robin B Gasser, Guangxu Ma

Journal article  |  2022  |  PLoS Negl Trop Dis

Toxocariasis is a neglected parasitic disease caused predominantly by larvae of Toxocara canis. While this zoonotic disease is of ..

Ubiquitination pathway model for the barber's pole worm - Haemonchus contortus

Yuanting Zheng, Guangxu Ma, Tao Wang, Andreas Hofmann, Jiangning Song, Robin B Gasser, Neil D Young

Journal article  |  2022  |  INTERNATIONAL JOURNAL FOR PARASITOLOGY

The ubiquitin-mediated pathway has been comprehensively explored in the free-living nematode Caenorhabditis elegans, but very litt..

Repurposing of a human antibody-based microarray to explore conserved components of the signalome of the parasitic nematode Haemonchus contortus.

Jack Adderley, Tao Wang, Guangxu Ma, Yuanting Zheng, Neil D Young, Christian Doerig, Robin B Gasser

Journal article  |  2022  |  Parasit Vectors

BACKGROUND: Gaining insight into molecular signalling pathways of socioeconomically important parasitic nematodes has implications..

Structural diversity of the ISCR2-mediated rolling-cycle transferable unit carrying tet(X4).

Dejun Liu, Tao Wang, Dongyan Shao, Huangwei Song, Weishuai Zhai, Chengtao Sun, Ying Zhang, Muchen Zhang, Yulin Fu, Rong Zhang, Tao He, Ziquan Lv, Li Bai, Congming Wu, Yuebin Ke, Yang Wang, Zhangqi Shen

Journal article  |  2022  |  Sci Total Environ

BACKGROUND: Mobile tigecycline-resistance gene tet(X) variants have emerged as diverse pathogens from animal, human as well as the..