Vinod Narayana

An integrated metagenomics and metabolomics approach implicates the microbiota-gut-brain axis in the pathogenesis of Huntington's disease.

Geraldine Kong, Susan Ellul, Vinod K Narayana, Komal Kanojia, Harvey Tran Thai Ha, Shanshan Li, Thibault Renoir, Kim-Anh Lê Cao, Anthony J Hannan

Journal article  |  2021  |  Neurobiology of Disease

BACKGROUND: Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder with onset and severity of symptoms infl..

Modulation of acyl-carnitines, the broad mechanism behind Wolbachia-mediated inhibition of medically important flaviviruses in Aedes aegypti

Gayathri Manokaran, Heather A Flores, Conor T Dickson, Vinod K Narayana, Komal Kanojia, Saravanan Dayalan, Dedreia Tull, Malcolm J McConville, Jason M Mackenzie, Cameron P Simmons

Journal article  |  2020  |  Proceedings of the National Academy of Sciences of USA

Wolbachia-infected mosquitoes are refractory to flavivirus infections, but the role of lipids in Wolbachia-mediated virus blocking..

Milk fat globule size development in the mammary epithelial cell: a potential role for ether phosphatidylethanolamine

Leonie Walter, Vinod K Narayana, Richard Fry, Amy Logan, Dedreia Tull, Brian Leury

Journal article  |  2020  |  Scientific Reports

Milk fat globule (MFG) size is a milk production trait characteristic to the individual animal and has important effects on the fu..

Microbe-Metabolite Associations Linked to the Rebounding Murine Gut Microbiome Postcolonization with Vancomycin-Resistant Enterococcus faecium

Andre Mu, Glen P Carter, Lucy Li, Nicole S Isles, Alison F Vrbanac, James T Morton, Alan K Jarmusch, David P De Souza, Vinod K Narayana, Komal Kanojia, Brunda Nijagal, Malcolm J McConville, Rob Knight, Benjamin P Howden, Timothy P Stinear

Journal article  |  2020  |  mSystems

Vancomycin-resistant Enterococcus faecium (VREfm) is an emerging antibiotic-resistant pathogen. Strain-level investigations are be..

High placental inositol content associated with suppressed pro-adipogenic effects of maternal glycaemia in offspring: the GUSTO cohort

Anne HY Chu, Mya T Tint, Hsin F Chang, Gerard Wong, Wen Lun Yuan, Dedreia Tull, Brunda Nijagal, Vinod K Narayana, Peter J Meikle, Kenneth TE Chang, Rohan M Lewis, Claudia Chi, Fabian KP Yap, Kok Hian Tan, Lynette P Shek, Yap-Seng Chong, Peter D Gluckman, Yung Seng Lee, Marielle Fortier, Keith M Godfrey, et al.

Journal article  |  2020  |  International Journal of Obesity

BACKGROUND/OBJECTIVES: Maternal glycaemia promotes fetal adiposity. Inositol, an insulin sensitizer, has been trialled for gestati..

Ribose-cysteine protects against the development of atherosclerosis in apoE-deficient mice

Tanjina Kader, Carolyn M Porteous, Gregory T Jones, Nina Dickerhof, Vinod K Narayana, Dedreia Tull, Sreya Taraknath, Sally PA McCormick

Journal article  |  2020  |  PLoS One

Ribose-cysteine is a synthetic compound designed to increase glutathione (GSH) synthesis. Low levels of GSH and the GSH-dependent ..

Stress signaling and cellular proliferation reverse the effects of mitochondrial mistranslation

Nicola Ferreira, Kara L Perks, Giulia Rossetti, Danielle L Rudler, Laetitia A Hughes, Judith A Ermer, Louis H Scott, Irina Kuznetsova, Tara R Richman, Vinod K Narayana, Laila N Abudulai, Anne-Marie J Shearwood, Henrietta Cserne Szappanos, Dedreia Tull, George C Yeoh, Livia C Hool, Aleksandra Filipovska, Oliver Rackham

Journal article  |  2019  |  The EMBO Journal

Translation fidelity is crucial for prokaryotes and eukaryotic nuclear-encoded proteins; however, little is known about the role o..

Review of recent developments in GC-MS approaches to metabolomics-based research

David J Beale, Farhana R Pinu, Konstantinos A Kouremenos, Mahesha M Poojary, Vinod K Narayana, Berin A Boughton, Komal Kanojia, Saravanan Dayalan, Oliver AH Jones, Daniel A Dias

Journal article  |  2018  |  Metabolomics

Profiling of Free Fatty Acids Using Stable Isotope Tagging Uncovers a Role for Saturated Fatty Acids in Neuroexocytosis

Vinod K Narayana, Vanesa M Tomatis, Tong Wang, David Kvaskoff, Frederic A Meunier

Journal article  |  2015  |  Cell Chemical Biology

PI3K delta inhibition reduces TNF secretion and neuroinflammation in a mouse cerebral stroke model

Pei Ching Regine Low, Silvia Manzanero, Vinod K Narayana, Tam H Nguyen, David Kvaskoff, Faith H Brennan, Marc J Ruitenberg, Mathias Gelderblom, Tim Magnus, Hyun Ah Kim, Brad RS Broughton, Christopher G Sobey, Bart Vanhaesebroeck, Jennifer L Stow, Thiruma V Arumugam, Frederic A Meunier

Conference Proceedings  |  2014  |  Cytokine