Steven Tong

A minimal common outcome measure set for COVID-19 clinical research.

undefined WHO Working Group on the Clinical Characterisation and Management of COVID-19 infection

Journal article  |  2020  |  The Lancet Infectious Diseases

Clinical research is necessary for an effective response to an emerging infectious disease outbreak. However, research efforts are..

Esomeprazole and sulfasalazine in combination additively reduce sFlt-1 secretion and diminish endothelial dysfunction: potential for a combination treatment for preeclampsia.

Natalie K Binder, Fiona C Brownfoot, Sally Beard, Ping Cannon, Tuong V Nguyen, Stephen Tong, Tu'uhevaha J Kaitu'u-Lino, Natalie J Hannan

Journal article  |  2020  |  Pregnancy Hypertension

Development and repurposing of therapies that show promise in the prevention or treatment of preeclampsia would be a major advance..

Antimicrobial stewardship in remote primary healthcare across northern Australia

Will Cuningham, Lorraine Anderson, Asha C Bowen, Kirsty Buising, Christine Connors, Kathryn Daveson, Joanna Martin, Stacey McNamara, Bhavini Patel, Rodney James, John Shanks, Kerr Wright, Trent Yarwood, Steven YC Tong, Jodie McVernon

Journal article  |  2020  |  PeerJ

The Australasian COVID-19 Trial (ASCOT) to assess clinical outcomes in hospitalised patients with SARS-CoV-2 infection (COVID-19) treated with lopinavir/ritonavir and/or hydroxychloroquine compared to standard of care: A structured summary of a study protocol for a randomised controlled trial.

Justin T Denholm, Joshua Davis, David Paterson, Jason Roberts, Susan Morpeth, Thomas Snelling, Dominica Zentner, Megan Rees, Matthew O'Sullivan, David Price, Asha Bowen, Steven YC Tong, undefined ASCOT Investigator Group

Journal article  |  2020  |  Trials

OBJECTIVES: To determine if lopinavir/ritonavir +/- hydroxychloroquine will reduce the proportion of participants who survive with..

A model of population dynamics with complex household structure and mobility: implications for transmission and control of communicable diseases

Rebecca Chisholm, Bradley Crammond, Yue Wu, Asha Bowen, Patricia Campbell, Steven Tong, Jodie McVernon, Nicholas Geard

Journal article  |  2020

Households are known to be high-risk locations for the transmission of communicable diseases. Numerous modelling studies have demo..

Clinical trials for the prevention and treatment ofCOVID-19: current state of play

Joshua S Davis, David Ferreira, Justin T Denholm, Steven YC Tong

Journal article  |  2020  |  Medical Journal of Australia

Since coronavirus disease 2019 (COVID-19) emerged in Wuhan, China in December 2019 and spread around the world, over 1100 clinical..

Complicated skin and soft tissue infections in remote indigenous communities

Lauren Thomas, Asha C Bowen, Steven YC Tong

Journal article  |  2020  |  Internal Medicine Journal

The burden and consequences of skin infections for remote living indigenous people are high. While skin infections are recognised ..

Combining metformin and sulfasalazine additively reduces the secretion of antiangiogenic factors from the placenta: Implications for the treatment of preeclampsia

Fiona C Brownfoot, Roxanne Hastie, Natalie J Hannan, Ping Cannon, Tuong Nguyen, Laura Tuohey, Cathy Cluver, Stephen Tong, Tu'uhevaha J Kaitu'u-Lino

Journal article  |  2020  |  Placenta

INTRODUCTION: The antiangiogenic factors soluble fms-like tyrosine kinase-1 (sFlt-1) and soluble endoglin (sENG) are elevated in p..

Epidemiological consequences of enduring strain-specific immunity requiring repeated episodes of infection

Rebecca H Chisholm, Nikki Sonenberg, Jake A Lacey, Malcolm I McDonald, Manisha Pandey, Mark R Davies, Steven YC Tong, Jodie McVernon, Nicholas Geard

Journal article  |  2020  |  PLOS COMPUTATIONAL BIOLOGY

Group A Streptococcus (GAS) skin infections are caused by a diverse array of strain types and are highly prevalent in disadvantage..

Epidemiological trends in notified influenza cases in Australia's Northern Territory, 2007-2016

Aaron L Weinman, Sheena G Sullivan, Dhanasekaran Vijaykrishna, Peter Markey, Avram Levy, Adrian Miller, Steven YC Tong

Journal article  |  2020  |  Influenza and Other Respiratory Viruses

Circulating mRNAs are differentially expressed in pregnancies with severe placental insufficiency and at high risk of stillbirth

Natalie J Hannan, Owen Stock, Rebecca Spencer, Clare Whitehead, Anna L David, Katie Groom, Scott Petersen, Amanda Henry, Joanne M Said, Sean Seeho, Stefan C Kane, Lavinia Gordon, Sally Beard, Kantaraja Chindera, Smita Karegodar, Richard Hiscock, Natasha Pritchard, Tu'uhevaha J Kaitu'u-Lino, Susan P Walker, Stephen Tong

Journal article  |  2020  |  BMC Medicine

BACKGROUND: Fetuses affected by placental insufficiency do not receive adequate nutrients and oxygenation, become growth restricte..

Circulating SPINT1 is a biomarker of pregnancies with poor placental function and fetal growth restriction

Tu'uhevaha J Kaitu'u-Lino, Teresa M MacDonald, Ping Cannon, Nguyen Tuong-Vi, Richard J Hiscock, Nick Haan, Jenny E Myers, Roxanne Hastie, Kirsten M Dane, Anna L Middleton, Intissar Bittar, Amanda N Sferruzzi-Perri, Natasha Pritchard, Alesia Harper, Natalie J Hannan, Valerie Kyritsis, Nick Crinis, Lisa Hui, Susan P Walker, Stephen Tong

Journal article  |  2020  |  Nature Communications

Placental insufficiency can cause fetal growth restriction and stillbirth. There are no reliable screening tests for placental ins..

Longitudinal Analysis of Group A Streptococcus emm Types and emm Clusters in a High-Prevalence Setting: Relationship between Past and Future Infections.

Patricia Therese Campbell, Steven YC Tong, Nicholas Geard, Mark R Davies, Kate A Worthing, Jake A Lacey, Pierre R Smeesters, Michael R Batzloff, Joseph Kado, Adam WJ Jenney, Jodie Mcvernon, Andrew C Steer

Journal article  |  2020  |  The Journal of Infectious Diseases

Group A Streptococcus is a pathogen of global importance, but despite the ubiquity of group A Streptococcus infections, the relati..

Reference exome data for Australian Aboriginal populations to support health-based research

Alexia L Weeks, Heather A D'Antoine, Melita McKinnon, Genevieve Syn, Dawn Bessarab, Ngiare Brown, Steven YC Tong, Bo Remenyi, Andrew Steer, Lesley-Ann Gray, Michael Inouye, Jonathan R Carapetis, Jenefer M Blackwell, Timo Lassmann

Journal article  |  2020  |  Scientific Data

Whole exome sequencing (WES) is a popular and successful technology which is widely used in both research and clinical settings. H..

A Scenario-Based Survey of Expert Echocardiography Recommendations for Patients With Staphylococcus aureus Bacteremia at Varying Risk for Endocarditis

George S Heriot, Steven YC Tong, Allen C Cheng, Danny Liew

Journal article  |  2020  |  JAMA Network Open

Pravastatin as the statin of choice for reducing pre-eclampsia-associated endothelial dysfunction

Natasha de Alwis, Sally Beard, Yeukai T Mangwiro, Natalie K Binder, Tu'uhevaha J Kaitu'u-Lino, Fiona C Brownfoot, Stephen Tong, Natalie J Hannan

Journal article  |  2020  |  Pregnancy Hypertension

OBJECTIVES: There is avid interest in pravastatin as a therapeutic intervention for pre-eclampsia, however little is known on stat..

Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe COVID-19

Irani Thevarajan, Thi HO Nguyen, Marios Koutsakos, Julian Druce, Leon Caly, Carolien E van de Sandt, Xiaoxiao Jia, Suellen Nicholson, Mike Catton, Benjamin Cowie, Steven YC Tong, Sharon R Lewin, Katherine Kedzierska

Journal article  |  2020  |  Nature Medicine

Restricted Sequence Variation in Streptococcus pyogenes Penicillin Binding Proteins

Andrew Hayes, Jake A Lacey, Jacqueline M Morris, Mark R Davies, Steven YC Tong

Journal article  |  2020  |  mSphere

A recent clinical report has linked Streptococcus pyogenes β-lactam antibiotic resistance to mutation in the penicillin binding pr..

Effect of Vancomycin or Daptomycin With vs Without an Antistaphylococcal beta-Lactam on Mortality, Bacteremia, Relapse, or Treatment Failure in Patients With MRSA Bacteremia A Randomized Clinical Trial

Steven YC Tong, David C Lye, Dafna Yahav, Archana Sud, J Owen Robinson, Jane Nelson, Sophia Archuleta, Matthew A Roberts, Alan Cass, David L Paterson, Hong Foo, Mical Paul, Stephen D Guy, Adrian R Tramontana, Genevieve B Walls, Stephen McBride, Narin Bak, Niladri Ghosh, Benjamin A Rogers, Anna P Ralph, et al.

Journal article  |  2020  |  JAMA

Importance: Methicillin-resistant Staphylococcus aureus (MRSA) bacteremia is associated with mortality of more than 20%. Combining..

Lessons learned in genetic research with Indigenous Australian participants

Steven YC Tong, Heather D'Antoine, Melita McKinnon, Kyle Turner, Maui Hudson, Ngiare Brown, Jonathan R Carapetis, Dawn C Bessarab

Journal article  |  2020  |  Medical Journal of Australia

Circulating Delta-like homolog 1 (DLK1) at 36 weeks is correlated with birthweight and is of placental origin

Teresa M MacDonald, Susan P Walker, Richard Hiscock, Ping Cannon, Alesia Harper, Elizabeth Murray, Lisa Hui, Kirsten Dane, Anna Middleton, Valerie Kyritsis, Natasha de Alwis, Natalie J Hannan, Stephen Tong, Tu'uhevaha J Kaitu'u-Lino

Journal article  |  2020  |  Placenta

Restricted sequence variation in Streptococcus pyogenes penicillin binding proteins

Andrew Hayes, Jake Lacey, Jacqueline Morris, Mark Davies, Steven YC Tong

Journal article  |  2020

Abstract A recent clinical report has linked Streptococcus pyogenes β-lactam antibiotic resistance to mutations in the Penicillin ..

Accuracy of clinical suspicion of growth restriction at term despite a normal growth ultrasound: A retrospective cohort study

Brittany Green, Lisa Hui, Roxanne Hastie, Stephen Tong, Fiona C Brownfoot

Journal article  |  2020  |  Australian and New Zealand Journal of Obstetrics and Gynaecology

Using genomics to understand meticillin- and vancomycin-resistant Staphylococcus aureus infections

Stefano G Giulieri, Steven YC Tong, Deborah A Williamson

Journal article  |  2020  |  Microbial Genomics

Resistance to meticillin and vancomycin in Staphylococcus aureus significantly complicates the management of severe infections lik..

Whole Genome Sequence Analysis and Population Genomics of Group A Streptococci.

Jake A Lacey, Taylah B James, Steven YC Tong, Mark R Davies

Journal article  |  2020  |  Methods in molecular biology (Clifton, N.J.)

Whole-genome sequencing (WGS) is used to determine the genetic composition of an organism. This fast-moving field is continually e..

Antibiotic use for Australian Aboriginal children in three remote Northern Territory communities.

Timothy Howarth, Raelene Brunette, Tanya Davies, Ross M Andrews, Bhavini K Patel, Steven Tong, Federica Barzi, Therese M Kearns

Journal article  |  2020  |  PLOS ONE

OBJECTIVE: To describe antibiotic prescription rates for Australian Aboriginal children aged <2 years living in three remote North..

Point of care and oral fluid hepatitis B testing in remote Indigenous communities of northern Australia

Richard P Sullivan, Jane Davies, Paula Binks, Roslyn Gundjirryiir Dhurrkay, George Garambaka Gurruwiwi, Sarah Mariyalawuy Bukulatjpi, Melita McKinnon, Kelly Hosking, Margaret Littlejohn, Kathy Jackson, Stephen Locarnini, Joshua S Davis, Steven YC Tong

Journal article  |  2019  |  Journal of Viral Hepatitis

Many Indigenous Australians in northern Australia living with chronic Hepatitis B are unaware of their diagnosis due to low screen..

Combination methotrexate and gefitinib: A potential medical treatment for inoperable nontubal ectopic pregnancy

Stella Italiano, Stephen Tong, Emma Readman, Meredith Tassone, Roxanne Hastie, Natasha Pritchard

Conference Proceedings  |  2019  |  Journal of Obstetrics and Gynaecology Research

Challenging immunodominance of influenza-specific CD8( ) T cell responses restricted by the risk-associated HLA-A*68:01 allomorph

CE van de Sandt, EB Clemens, EJ Grant, LC Rowntree, S Sant, H Halim, J Crowe, AC Cheng, TC Kotsimbos, M Richards, A Miller, SYC Tong, J Rossjohn, THO Nguyen, S Gras, W Chen, K Kedzierska

Journal article  |  2019  |  Nature Communications

Although influenza viruses lead to severe illness in high-risk populations, host genetic factors associated with severe disease ar..

A Survey of Infectious Diseases and Microbiology Clinicians in Australia and New Zealand About the Management of Staphylococcus aureus Bacteremia

Steven YC Tong, Anita Campbell, Asha C Bowen, Joshua S Davis

Journal article  |  2019  |  Clinical Infectious Diseases

Towards Genotype-Specific Care for Chronic Hepatitis B: The First 6 Years Follow Up From the CHARM Cohort Study

Jane Davies, Emma L Smith, Margaret Littlejohn, Rosalind Edwards, Vitina Sozzi, Kathy Jackson, Katie McGuire, Paula Binks, Benjamin C Cowie, Stephen Locarnini, Joshua S Davis, Steven YC Tong

Journal article  |  2019  |  Open Forum Infectious Diseases

Sulfasalazine decreases soluble fms-like tyrosine kinase-1 secretion potentially via inhibition of upstream placental epidermal growth factor receptor signalling

Roxanne Hastie, Fiona C Brownfoot, Ping Cannon, Nguyen Vi, Laura Tuohey, Natalie J Hannan, Stephen Tong, Tu'uhevaha J Kaitu'u-Lino

Journal article  |  2019  |  Placenta

OBJECTIVES: Preeclampsia is a hypertensive disorder of pregnancy with no available medical treatment. We recently reported sulfasa..

Evolution and Global Transmission of a Multidrug-Resistant, Community-Associated Methicillin-Resistant Staphylococcus aureus Lineage from the Indian Subcontinent

Eike J Steinig, Sebastian Duchene, D Ashley Robinson, Stefan Monecke, Maho Yokoyama, Maisem Laabei, Peter Slickers, Patiyan Andersson, Deborah Williamson, Angela Kearns, Richard V Goering, Elizabeth Dickson, Ralf Ehricht, Margaret Ip, Matthew VN O'Sullivan, Geoffrey W Coombs, Andreas Petersen, Grainne Brennan, Anna C Shore, David C Coleman, et al.

Journal article  |  2019  |  mBio

The evolution and global transmission of antimicrobial resistance have been well documented for Gram-negative bacteria and health ..

Benzylpenicillin versus flucloxacillin for penicillin-susceptible Staphylococcus aureus bloodstream infections from a large retrospective cohort study

A Henderson, P Harris, G Hartel, D Paterson, J Turnidge, JS Davis, SYC Tong

Journal article  |  2019  |  International Journal of Antimicrobial Agents

In clinical practice, differing opinion exists as to the optimal management of patients with penicillin susceptible Staphylococcus..

Screening circulating proteins to identify biomarkers of fetal macrosomia.

Tess Cruickshank, Tu'uhevaha J Kaitu'u-Lino, Ping Cannon, Alesia Harper, Tuong-Vi Nguyen, Kirsten M Dane, Anna L Middleton, Valerie P Kyritsis, Roxanne Hastie, Stephen Tong, Susan P Walker, Teresa M MacDonald

Journal article  |  2019  |  BMC Research Notes

OBJECTIVE: Fetal macrosomia is a major risk factor for shoulder dystocia, which can lead to birth asphyxia, maternal and neonatal ..

Perinatal risk factors associated with skin infection hospitalisation in Western Australian Aboriginal and Non-Aboriginal children

Rosanne Barnes, Asha C Bowen, Roz Walker, Steven YC Tong, Jodie McVernon, Patricia T Campbell, Parveen Fathima, Nicholas H de Klerk, Yue Wu, Christopher C Blyth, Jonathan R Carapetis, Hannah C Moore

Journal article  |  2019  |  Paediatric and Perinatal Epidemiology

SToP (See, Treat, Prevent) skin sores and scabies trial: study protocol for a cluster randomised, stepped-wedge trial for skin disease control in remote Western Australia

Marianne J Mullane, Timothy C Barnett, Jeffrey W Cannon, Jonathan R Carapetis, Ray Christophers, Juli Coffin, Mark A Jones, Julie A Marsh, Frieda Mc Loughlin, Vicki O'Donnell, Rebecca Pavlos, Bec Smith, Andrew C Steer, Steven YC Tong, Roz Walker, Asha C Bowen

Journal article  |  2019  |  BMJ Open

INTRODUCTION: Skin is important in Australian Aboriginal culture informing kinship and identity. In many remote Aboriginal communi..

Cerebral-placental-uterine ratio as novel predictor of late fetal growth restriction: prospective cohort study

TM Macdonald, L Hui, AJ Robinson, KM Dane, AL Middleton, S Tong, SP Walker

Journal article  |  2019  |  Ultrasound in Obstetrics & Gynecology

OBJECTIVES: Fetal growth restriction (FGR) is a major risk factor for stillbirth and most commonly arises from uteroplacental insu..

Early transthoracic echocardiography has useful prognostic value in left-sided native valve endocarditis despite limited diagnostic performance

George S Heriot, Andrew Newcomb, Jonathan Darby, Andrew Wilson, Steven YC Tong, Allen C Cheng, Danny Liew

Journal article  |  2019  |  European Journal of Clinical Microbiology & Infectious Diseases

Povidone-iodine ear wash and oral cotrimoxazole for chronic suppurative otitis media in Australian aboriginal children: study protocol for factorial design randomised controlled trial

Christine Wigger, Amanda Jane Leach, Jemima Beissbarth, Victor Oguoma, Ruth Lennox, Sandra Nelson, Hemi Patel, Mark Chatfield, Kathy Currie, Harvey Coates, Keith Edwards, Heidi Smith-Vaughan, Kim Hare, Paul Torzillo, Steven Tong, Peter Morris

Journal article  |  2019  |  BMC Pharmacology and Toxicology

BACKGROUND: Chronic suppurative otitis media (CSOM) is a significant health issue affecting Aboriginal Australians. Long-term hear..

Concerns for efficacy of a 30-valent M-protein-based Streptococcus pyogenes vaccine in regions with high rates of rheumatic heart disease

Philip M Giffard, Steven YC Tong, Deborah C Holt, Anna P Ralph, Bart J Currie

Journal article  |  2019  |  PLOS Neglected Tropical Diseases

The prevalence of rheumatic heart disease (RHD) in the Aboriginal population of the Australian Northern Territory is high, and Str..

When Ventricular Cerebrospinal Fluid Assessment Misleads: Basal Meningitis and the Importance of Lumbar Puncture Sampling

Sadid F Khan, Thornton Macauley, Steven YC Tong, Ouli Xie, Carly Hughes, Nicholas DP Hall, Siddhartha Mahanty, Ian Jennens, Alan C Street

Journal article  |  2019  |  OPEN FORUM INFECTIOUS DISEASES

The diagnosis of central nervous system (CNS) infection relies upon analysis of cerebrospinal fluid (CSF). We present 4 cases of C..

An urgent need for antimicrobial stewardship in Indigenous rural and remote primary health care

Asha C Bowen, Kathryn Daveson, Lorraine Anderson, Steven YC Tong

Journal article  |  2019  |  Medical Journal of Australia

Infectious Diseases Clinician's Variation in the Management of Pediatric Staphylococcus aureus Bacteraemia and Equipoise for Clinical Trials

Anita J Campbell, Steven YC Tong, Joshua S Davis, Alasdair PS Munro, Christopher C Blyth, Asha C Bowen

Journal article  |  2019  |  Frontiers in Pediatrics

Epidemiological consequences of enduring strain-specific immunity requiring repeated episodes of infection

Rebecca Chisholm, Nikki Sonenberg, Jake Lacey, Malcolm McDonald, Manisha Pandey, Mark Davies, Steven Tong, Jodie McVernon, Nicholas Geard

Journal article  |  2019

Abstract Group A Streptococcus (GAS) skin infections are caused by a diverse array of strain types and are highly prevalent in Ind..

CASSETTEclindamycin adjunctive therapy for severe Staphylococcus aureus treatment evaluation: study protocol for a randomised controlled trial

Ravindra Dotel, Steven YC Tong, Asha Bowen, Jane N Nelson, Matthew VN O'Sullivan, Anita J Campbell, Brendan J McMullan, Philip N Britton, Joshua R Francis, Damon P Eisen, Owen Robinson, Laurens Manning, Joshua S Davis

Journal article  |  2019  |  TRIALS

Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics

Mark R Davies, Liam McIntyre, Ankur Mutreja, Jake A Lacey, John A Lees, Rebecca J Towers, Sebastian Duchene, Pierre R Smeesters, Hannah R Frost, David J Price, Matthew TG Holden, Sophia David, Philip M Giffard, Kate A Worthing, Anna C Seale, James A Berkley, Simon R Harris, Tania Rivera-Hernandez, Olga Berking, Amanda J Cork, et al.

Journal article  |  2019  |  Nature Genetics

Good Studies Evaluate the Disease While Great Studies Evaluate the Patient: Development and Application of a Desirability of Outcome Ranking Endpoint for Staphylococcus aureus Bloodstream Infection

Sarah B Doernberg, Tien Tram Tran Thuy, Steven YC Tong, Mical Paul, Dafna Yahav, Joshua S Davis, Leonard Leibovici, Helen W Boucher, G Ralph Corey, Sara E Cosgrove, Henry F Chambers, Vance G Fowler, Scott R Evans, Thomas L Holland

Journal article  |  2019  |  Clinical Infectious Diseases

Background: Desirability of outcome ranking (DOOR) is an innovative approach in clinical trials to evaluate the global benefits an..

Mycobacterial mimicry in a man from Myanmar

David WJ Griffin, G Khai Lin Huang, Philippe Lachapelle, Steven YC Tong, Siddhartha Mahanty

Journal article  |  2019  |  Medical Journal of Australia

Tracing Ancient Human Migrations into Sahul Using Hepatitis B Virus Genomes

Lilly KW Yuen, Margaret Littlejohn, Sebastian Duchene, Rosalind Edwards, Sarah Bukulatjpi, Paula Binks, Kathy Jackson, Jane Davies, Joshua S Davis, Steven YC Tong, Stephen Locarnini

Journal article  |  2019  |  Molecular Biology and Evolution

High burden of infectious disease and antibiotic use in early life in Australian Aboriginal communities

Will Cuningham, Jodie McVernon, Michael J Lydeamore, Ross M Andrews, Jonathan Carapetis, Therese Kearns, Danielle Clucas, Roslyn Gundjirryirr Dhurrkay, Steven YC Tong, Patricia T Campbell

Journal article  |  2019  |  Australian and New Zealand Journal of Public Health

The epidemiology of Staphylococcus aureus skin and soft tissue infection in the southern Barkly region of Australia's Northern Territory in 2017

Richard X Davey, Steven YC Tong

Journal article  |  2019  |  Pathology

Potential for Molecular Testing for Group A Streptococcus to Improve Diagnosis and Management in a High-Risk Population: A Prospective Study

Anna P Ralph, Deborah C Holt, Sharifun Islam, Joshua Osowicki, David E Carroll, Steven YC Tong, Asha C Bowen

Journal article  |  2019  |  OPEN FORUM INFECTIOUS DISEASES

Burden of skin disease in two remote primary healthcare centres in northern and central Australia

Lauren Thomas, Asha C Bowen, Marleesa Ly, Christine Connors, Ross Andrews, Steven YC Tong

Journal article  |  2019  |  Internal Medicine Journal

Treatment, prevention and public health management of impetigo, scabies, crusted scabies and fungal skin infections in endemic populations: a systematic review

Philippa J May, Steven YC Tong, Andrew C Steer, Bart J Currie, Ross M Andrews, Jonathan R Carapetis, Asha C Bowen

Journal article  |  2019  |  Tropical Medicine & International Health

A biological model of scabies infection dynamics and treatment informs mass drug administration strategies to increase the likelihood of elimination

MJ Lydeamore, PT Campbell, DG Regan, SYC Tong, RM Andrews, AC Steer, L Romani, JM Kaldor, J McVernon, JM McCaw

Journal article  |  2019  |  Mathematical Biosciences

Incidence of community onset MRSA in Australia: least reported where it is Most prevalent

Jessica K Cameron, Lisa Hall, Steven YC Tong, David L Paterson, Kate Halton

Journal article  |  2019  |  Antimicrobial Resistance & Infection Control

Adjunctive protein synthesis inhibitor antibiotics for toxin suppression in Staphylococcus aureus infections: a systematic appraisal

AJ Campbell, R Dotel, CC Blyth, JS Davis, SYC Tong, AC Bowen

Journal article  |  2019  |  Journal of Antimicrobial Chemotherapy

Systematic Review of Group A Streptococcal emm Types Associated with Acute Post-Streptococcal Glomerulonephritis

Kate A Worthing, Jake A Lacey, David J Price, Liam McIntyre, Andrew C Steer, Steven YC Tong, Mark R Davies

Journal article  |  2019  |  The American Journal of Tropical Medicine and Hygiene

What risk of endocarditis is low enough to justify the omission of transoesophageal echocardiography in Staphylococcus aureus bacteraemia? A narrative review

GS Heriot, SYC Tong, AC Cheng, D Liew

Journal article  |  2018  |  Clinical Microbiology and Infection

Benefit of Echocardiography in Patients With Staphylococcus aureus Bacteremia at Low Risk of Endocarditis

George S Heriot, Steven YC Tong, Allen C Cheng, Danny Liew

Journal article  |  2018  |  Open Forum Infectious Diseases

Staphylococcus aureus from patients with chronic rhinosinusitis show minimal genetic association between polyp and non-polyp phenotypes

Jake Jervis Bardy, Derek S Sarovich, Erin P Price, Eike Steinig, Steven Tong, Amanda Drilling, Judy Ou, Sarah Vreugde, Peter-John Wormald, Alkis J Psaltis

Journal article  |  2018  |  BMC EAR NOSE AND THROAT DISORDERS

Gene exchange drives the ecological success of a multi-host bacterial pathogen

Emily J Richardson, Rodrigo Bacigalupe, Ewan M Harrison, Lucy A Weinert, Samantha Lycett, Manouk Vrieling, Kirsty Robb, Paul A Hoskisson, Matthew TG Holden, Edward J Feil, Gavin K Paterson, Steven YC Tong, Adebayo Shittu, Willem van Wamel, David M Aanensen, Julian Parkhill, Sharon J Peacock, Jukka Corander, Mark Holmes, J Ross Fitzgerald

Journal article  |  2018  |  Nature Ecology & Evolution

Investigation of trimethoprim/sulfamethoxazole resistance in an emerging sequence type 5 methicillin-resistant Staphylococcus aureus clone reveals discrepant resistance reporting

TM Harris, AC Bowen, DC Holt, DS Sarovich, K Stevens, BJ Currie, BP Howden, JR Carapetis, PM Giffard, SYC Tong

Journal article  |  2018  |  Clinical Microbiology and Infection

A large retrospective cohort study of cefazolin compared with flucloxacillin for methicillin-susceptible Staphylococcus aureus bacteraemia

JS Davis, J Turnidge, SYC Tong

Journal article  |  2018  |  International Journal of Antimicrobial Agents

Global Scale Dissemination of ST93: A Divergent Staphylococcus aureus Epidemic Lineage That Has Recently Emerged From Remote Northern Australia

Sebastiaan J van Hal, Eike J Steinig, Patiyan Andersson, Matthew TG Holden, Simon R Harris, Graeme R Nimmo, Deborah A Williamson, Helen Heffernan, SR Ritchie, Angela M Kearns, Matthew J Ellington, Elizabeth Dickson, Herminia De Lencastre, Geoffrey W Coombs, Stephen D Bentley, Julian Parkhill, Deborah C Holt, Phillip M Giffard, Steven YC Tong

Journal article  |  2018  |  Frontiers in Microbiology

Calculation of the age of the first infection for skin sores and scabies in five remote communities in northern Australia

MJ Lydeamore, PT Campbell, W Cuningham, RM Andrews, T Kearns, D Clucas, R Gundjirryirr Dhurrkay, J Carapetis, SYC Tong, JM McCaw, J McVernon

Journal article  |  2018  |  Epidemiology and Infection

Scabies and risk of skin sores in remote Australian Aboriginal communities: A self-controlled case series study

Thu Zar Aung Phyo, Will Cuningham, Kerry Hwang, Ross M Andrews, Jonathan Carapetis, Therese Kearns, Danielle Clucas, Jodie McVernon, Julie Ann Simpson, Steven Tong, Patricia Therese Campbell

Journal article  |  2018  |  PLOS NEGLECTED TROPICAL DISEASES

Sub-optimal protection against past hepatitis B virus infection where subtype mismatch exists between vaccine and circulating viral genotype in northern Australia

Benjamin C Cheah, Jane Davies, Gurmeet R Singh, Nicholas Wood, Kathy Jackson, Margaret Littlejohn, Belinda Davison, Peter McIntyre, Stephen Locarnini, Joshua S Davis, Steven YC Tong

Journal article  |  2018  |  Vaccine

Antimicrobial resistance in urine and skin isolates in Timor-Leste

Ian Marr, Nevio Sarmento, Matt O'Brien, Karl Lee, Celia Gusmao, Gloria de Castro, Sonja Janson, Steven YC Tong, Rob W Baird, Joshua R Francis

Journal article  |  2018  |  Journal of Global Antimicrobial Resistance

Streptococcus gallolyticus subsp pasteurianus meningitis complicated by venous sinus thrombosis: A case report

Martin Wardle, Andre Mu, Steven YC Tong

Journal article  |  2018  |  International Journal of Infectious Diseases

The unique aspects of chronic hepatitis B infection in Aboriginal and Torres Strait Islander people

Jane Davies, Craig S Boutlis, Catherine S Marshall, Steven YC Tong, Joshua S Davis

Journal article  |  2018  |  Internal Medicine Journal

Clinical variation in the use of echocardiography in Staphylococcus aureus bacteraemia: a multi-centre cohort study

George S Heriot, Steven YC Tong, Allen C Cheng, Irani Thevarajan, Michele R Levinson, Kumar Visvanathan, Danny Liew

Journal article  |  2018  |  European Journal of Clinical Microbiology & Infectious Diseases

Contaminated fingers: a potential cause of Chlamydia trachomatis-positive urine specimens

Philip M Giffard, Rachael A Lilliebridge, Judith Wilson, Gerald Murray, Samuel Phillips, Sepehr N Tabrizi, Suzanne M Garland, Louise Martin, Gurmeet Singh, Steven YC Tong, Deborah C Holt, Patiyan Andersson

Journal article  |  2018  |  Sexually Transmitted Infections

Immortal Time Bias in Assessing Evidence-Based Care Processes for Staphylococcus aureus Bacteremia

Steven YC Tong, Allen C Cheng, Justin T Denholm

Journal article  |  2018  |  JAMA Internal Medicine

Implications of asymptomatic carriers for infectious disease transmission and control

Rebecca H Chisholm, Patricia T Campbell, Yue Wu, Steven YC Tong, Jodie McVernon, Nicholas Geard

Journal article  |  2018  |  ROYAL SOCIETY OPEN SCIENCE

Evolution and global transmission of a multidrug-resistant, community-associated MRSA lineage from the Indian subcontinent

Eike Steinig, Sebastian Duchene, Ashley Robinson, Stefan Monecke, Maho Yokoyama, Maisem Laabei, Peter Slickers, Patiyan Andersson, Deborah Williamson, Angela Kearns, Richard Goering, Elizabeth Dickson, Ralf Ehricht, Margaret Ip, Mathew VN O’Sullivan, Geoffrey Coombs, Andreas Petersen, Grainne Brennan, Anna Shore, David Coleman, et al.

Journal article  |  2017

Abstract The evolution and global transmission of antimicrobial resistance has been well documented in Gram-negative bacteria and ..

Genome-Wide Analysis of Genetic Risk Factors for Rheumatic Heart Disease in Aboriginal Australians Provides Support for Pathogenic Molecular Mimicry

Lesley-Ann Gray, Heather A D'Antoine, Steven YC Tong, Melita McKinnon, Dawn Bessarab, Ngiare Brown, Bo Remenyi, Andrew Steer, Genevieve Syn, Jenefer M Blackwell, Michael Inouye, Jonathan R Carapetis

Journal article  |  2017  |  The Journal of Infectious Diseases

Indigenous Australian household structure: a simple data collection tool and implications for close contact transmission of communicable diseases

Thiripura vino, Gurmeet R Singh, Belinda Davision, Patricia T Campbell, Michael J Lydeamore, Andrew Robinson, Jodie McVernon, Steven YC Tong, Nicholas Geard

Journal article  |  2017  |  PEERJ

The rise of methicillin resistant Staphylococcus aureus: now the dominant cause of skin and soft tissue infection in Central Australia

E Macmorran, S Harch, E Athan, S Lane, S Tong, L Crawford, S Krishnaswamy, S Hewagama

Journal article  |  2017  |  Epidemiology and Infection

Genome-wide analysis of genetic risk factors for rheumatic heart disease in Aboriginal Australians provides support for pathogenic molecular mimicry

Lesley-Ann Gray, Heather D’Antoine, Steven Tong, Melita McKinnon, Dawn Bessarab, Ngiare Brown, Bo Reményi, Andrew Steer, Genevieve Syn, Jenefer Blackwell, Michael Inouye, Jonathan Carapetis

Journal article  |  2017

Abstract Background Rheumatic heart disease (RHD) following Group A Streptococcus (GAS) infections is heritable and prevalent in I..

Establishing contemporary trends in hepatitis B sero-epidemiology in an Indigenous population

Jane Davies, Shu Qin Li, Steven Y Tong, Rob W Baird, Miles Beaman, Geoff Higgins, Benjamin C Cowie, John R Condon, Joshua S Davis

Journal article  |  2017  |  PLOS ONE

Sulfamethoxazole-Trimethoprim (Cotrimoxazole) for Skin and Soft Tissue Infections Including Impetigo, Cellulitis, and Abscess

Asha C Bowen, Jonathan R Carapetis, Bart J Currie, Vance Fowler, Henry F Chambers, Steven YC Tong

Journal article  |  2017  |  Open Forum Infectious Diseases

Criteria for Identifying Patients With Staphylococcus aureus Bacteremia Who Are at Low Risk of Endocarditis: A Systematic Review

George S Heriot, Katie Cronin, Steven YC Tong, Allen C Cheng, Danny Liew

Journal article  |  2017  |  Open Forum Infectious Diseases

Prolonged Detection of Japanese Encephalitis Virus in Urine and Whole Blood in a Returned Short-term Traveler

G Khai Lin Huang, Shio Yen Tio, Leon Caly, Suellen Nicholson, Irani Thevarajan, Georgina Papadakis, Mike Catton, Steven YC Tong, Julian Druce

Journal article  |  2017  |  Open Forum Infectious Diseases

Proposed primary endpoints for use in clinical trials that compare treatment options for bloodstream infection in adults: a consensus definition

PNA Harris, JF McNamara, DC Lye, JS Davis, L Bernard, AC Cheng, Y Doi, VG Fowler, KS Kaye, L Leibovici, J Lipman, MJ Llewelyn, S Munoz-Price, M Paul, AY Peleg, J Rodriguez-Bano, BA Rogers, H Seifert, V Thamlikitkul, G Thwaites, et al.

Journal article  |  2017  |  Clinical Microbiology and Infection

Staphylococcus aureus Prostatic abscess: a clinical case report and a review of the literature

David E Carroll, Ian Marr, G Khai Lin Huang, Deborah C Holt, Steven YC Tong, Craig S Boutlis

Journal article  |  2017  |  BMC Infectious Diseases

Indigenous Australian household structure: a simple data collection tool and implications for close contact transmission of communicable diseases

Thiripura Vino, Gurmeet Singh, Belinda Davison, Patricia Campbell, Michael Lydeamore, Andrew Robinson, Jodie McVernon, Steven YC Tong, Nicholas Geard

Journal article  |  2017

Households are an important location for the transmission of communicable diseases. Social contact between household members is ty..

High burden of complicated skin and soft tissue infections in the Indigenous population of Central Australia due to dominant Panton Valentine leucocidin clones ST93-MRSA and CC121-MSSA

Susan AJ Harch, Eleanor MacMorran, Steven YC Tong, Deborah C Holt, Judith Wilson, Eugene Athan, Saliya Hewagama

Journal article  |  2017  |  BMC Infectious Diseases

A double-blind randomized controlled trial of ibuprofen compared to placebo for uncomplicated cellulitis of the upper or lower limb

JS Davis, C Mackrow, P Binks, W Fletcher, P Dettwiller, C Marshall, J Day, W Pratt, SYC Tong

Journal article  |  2017  |  Clinical Microbiology and Infection

Targeting Staphylococcus aureus in Pediatric Surviving Sepsis Bundles Reply

Brendan J McMullan, Asha C Bowen, Steven YC Tong

Journal article  |  2017  |  JAMA Pediatrics

Bacteremia, Sepsis, and Infective Endocarditis Associated with Staphylococcus aureus

Stephen P Bergin, Thomas L Holland, Vance G Fowler, Steven YC Tong

Book Chapter  |  2017  |  Current Topics in Microbiology and Immunology

Whole genome sequencing to investigate a putative outbreak of the virulent community-associated methicillin-resistant Staphylococcus aureus ST93 clone in a remote Indigenous community

Ella M Meumann, Patiyan Andersson, Fiona Yeaman, Sarah Oldfield, Rachael Lilliebridge, Stephen D Bentley, Vicki Krause, Miles Beaman, Bart J Currie, Deborah C Holt, Philip M Giffard, Steven YC Tong

Journal article  |  2016  |  Microbial Genomics

Comparative M-protein analysis of Streptococcus pyogenes from pharyngitis and skin infections in New Zealand: Implications for vaccine development

Deborah A Williamson, Pierre R Smeesters, Andrew C Steer, Julie Morgan, Mark Davies, Philip Carter, Arlo Upton, Stephen YC Tong, John Fraser, Nicole J Moreland

Journal article  |  2016  |  BMC Infectious Diseases

Nocardiosis in the tropical northern territory of Australia, 1997-2014

SL McGuinness, SE Whiting, R Baird, BJ Currie, AP Ralph, NM Anstey, RN Price, JS Davis, SYC Tong

Journal article  |  2016  |  Open Forum Infectious Diseases

Epidemiology and Mortality of Staphylococcus aureus Bacteremia in Australian and NewZealand Children

Brendan J McMullan, Asha Bowen, Christopher C Blyth, Sebastiaan Van Hal, Tony M Korman, Jim Buttery, Lesley Voss, Sally Roberts, Celia Cooper, Steven YC Tong, John Turnidge

Journal article  |  2016  |  JAMA Pediatrics

Nocardiosis in the Tropical Northern Territory of Australia, 1997-2014.

Sarah L McGuinness, Sarah E Whiting, Rob Baird, Bart J Currie, Anna P Ralph, Nicholas M Anstey, Ric N Price, Joshua S Davis, Steven YC Tong

Journal article  |  2016  |  Open Forum Infectious Diseases

BACKGROUND: Nocardia is an opportunistic pathogen that can cause life-threatening disease. We aimed to characterize the epidemiolo..

Towards identification of immune and genetic correlates of severe influenza disease in Indigenous Australians

EB Clemens, EJ Grant, Z Wang, S Gras, N Mifsud, P Illing, P Tipping, AW Purcell, J Rossjohn, A Miller, SYC Tong, K Kedzierska

Conference Proceedings  |  2016  |  EUROPEAN JOURNAL OF IMMUNOLOGY

Echocardiographic agreement in the diagnostic evaluation for infective endocarditis

Trine Kiilerich Lauridsen, Christine Selton-Suty, Steven Tong, Luis Afonso, Enrico Cecchi, Lawrence Park, Eric Yow, Huiman X Barnhart, Carlos Pare, Zainab Samad, Donald Levine, Gail Peterson, Amy Butler Stancoven, Magnus Carl Johansson, Stuart Dickerman, Syahidah Tamin, Gilbert Habib, Pamela S Douglas, Niels Eske Bruun, Anna Lisa Crowley

Journal article  |  2016  |  The International Journal of Cardiovascular Imaging

Recurrent Visual Electronic Hand Hygiene Reminders in the Anesthesia Work Area.

David Rodriguez-Aldrete, Eellan Sivanesan, Shawn Banks, Ana Mavarez, Kristopher Arheart, Scott Eber, L Silvia Munoz-Price

Journal article  |  2016  |  Infection Control & Hospital Epidemiology

Whole genome sequencing reveals extensive community-level transmission of group A Streptococcus in remote communities

AC Bowen, T Harris, DC Holt, PM Giffard, JR Carapetis, PT Campbell, J McVernon, SYC Tong

Journal article  |  2016  |  EPIDEMIOLOGY AND INFECTION

The Importance of Scabies Coinfection in the Treatment Considerations for Impetigo

Monika Tasani, Steven YC Tong, Ross M Andrews, Deborah C Holt, Bart J Currie, Jonathan R Carapetis, Asha C Bowen

Journal article  |  2016  |  The Pediatric Infectious Disease Journal

Towards identification of immune and genetic correlates of severe influenza disease in Indigenous Australians

E Bridie Clemens, Emma J Grant, Zhongfang Wang, Stephanie Gras, Peta Tipping, Jamie Rossjohn, Adrian Miller, Steven YC Tong, Katherine Kedzierska

Journal article  |  2016  |  IMMUNOLOGY AND CELL BIOLOGY

Reduction in Staphylococcus aureus bacteraemia rates in patients receiving haemodialysis following alteration of skin antisepsis procedures

BJ Stewart, T Gardiner, GJ Perry, SYC Tong

Journal article  |  2016  |  Journal of Hospital Infection

Differing epidemiology of two major healthcare-associated meticillin-resistant Staphylococcus aureus clones

CJ Jeremiah, JP Kandiah, DW Spelman, PM Giffard, GW Coombs, AW Jenney, SY Tong

Journal article  |  2016  |  Journal of Hospital Infection

Combination of Vancomycin and beta-Lactam Therapy for Methicillin-Resistant Staphylococcus aureus Bacteremia: A Pilot Multicenter Randomized Controlled Trial

Joshua S Davis, Archana Sud, Matthew VN O'Sullivan, James O Robinson, Patricia E Ferguson, Hong Foo, Sebastiaan J van Hal, Anna P Ralph, Benjamin P Howden, Paula M Binks, Adrienne Kirby, Steven YC Tong

Journal article  |  2016  |  Clinical Infectious Diseases

Protocol for the systematic review of the prevention, treatment and public health management of impetigo, scabies and fungal skin infections in resource-limited settings

Philippa May, Asha Bowen, Steven Tong, Andrew Steer, Sam Prince, Ross Andrews, Bart Currie, Jonathan Carapetis

Journal article  |  2016  |  Systematic Reviews

Staphylococcus aureus infections following knee and hip prosthesis insertion procedures

Jean Marie Arduino, Keith S Kaye, Shelby D Reed, Senaka A Peter, Daniel J Sexton, Luke F Chen, N Chantelle Hardy, Steven YC Tong, Steven S Smugar, Vance G Fowler, Deverick J Anderson

Journal article  |  2015  |  Antimicrobial Resistance and Infection Control

Reduced In Vitro Activity of Ceftaroline by Etest among Clonal Complex 239 Methicillin-Resistant Staphylococcus aureus Clinical Strains from Australia

IJ Abbott, AWJ Jenney, CJ Jeremiah, M Mirceta, JP Kandiah, DC Holt, SYC Tong, DW Spelman

Journal article  |  2015  |  Antimicrobial Agents and Chemotherapy

Scabies coinfection in the treatment considerations for impetigo

M Tasani, SYC Tong, RM Andrews, D Holt, BJ Currie, JR Carapetis, AC Bowen

Conference Proceedings  |  2015  |  BRITISH JOURNAL OF DERMATOLOGY

The role of Staphylococcal carotenogenesis in resistance to host defense peptides and in vivo virulence in experimental endocarditis model

Yan Q Xiong, Soo-Jin Yang, Steven YC Tong, Danya N Alvarez, Nagendra N Mishra

Journal article  |  2015  |  Pathogens and Disease

The Global Epidemiology of Impetigo: A Systematic Review of the Population Prevalence of Impetigo and Pyoderma

Asha C Bowen, Antoine Mahe, Roderick J Hay, Ross M Andrews, Andrew C Steer, Steven YC Tong, Jonathan R Carapetis

Journal article  |  2015  |  PLOS ONE

Echocardiographic Findings Predict In-Hospital and 1-Year Mortality in Left-Sided Native Valve Staphylococcus aureus Endocarditis Analysis From the International Collaboration on Endocarditis-Prospective Echo Cohort Study

Trine K Lauridsen, Lawrence Park, Steven YC Tong, Christine Selton-Suty, Gail Peterson, Enrico Cecchi, Luis Afonso, Gilbert Habib, Carlos Pare, Syahidah Tamin, Stuart Dickerman, Arnold S Bayer, Magnus C Johansson, Vivian H Chu, Zainab Samad, Niels E Bruun, Vance G Fowler, Anna Lisa Crowley

Journal article  |  2015  |  Circulation: Cardiovascular Imaging

Staphylococcus aureus Infections: Epidemiology, Pathophysiology, Clinical Manifestations, and Management

Steven YC Tong, Joshua S Davis, Emily Eichenberger, Thomas L Holland, Vance G Fowler

Journal article  |  2015  |  Clinical Microbiology Reviews

Single-molecule sequencing reveals the molecular basis of multidrug-resistance in ST772 methicillin-resistant Staphylococcus aureus

Eike J Steinig, Patiyan Andersson, Simon R Harris, Derek S Sarovich, Anand Manoharan, Paul Coupland, Matthew TG Holden, Julian Parkhill, Stephen D Bentley, D Ashley Robinson, Steven YC Tong

Journal article  |  2015  |  BMC Genomics

Progressive increase in community-associated methicillin-resistant Staphylococcus aureus in Indigenous populations in northern Australia from 1993 to 2012

SYC Tong, L Varrone, MD Chatfield, M Beaman, PM Giffard

Journal article  |  2015  |  Epidemiology and Infection

Treatment of Methicillin-Resistant Staphylococcus aureus: Vancomycin and Beyond

Natasha E Holmes, Steven YC Tong, Joshua S Davis, Sebastiaan J van Hal

Journal article  |  2015  |  Seminars in Respiratory and Critical Care Medicine

Combination Antibiotic Treatment of Serious Methicillin-Resistant Staphylococcus aureus Infections

JS Davis, S Van Hal, SYC Tong

Journal article  |  2015  |  Seminars in Respiratory and Critical Care Medicine

Novel staphylococcal species that form part of a Staphylococcus aureus-related complex: the non-pigmented Staphylococcus argenteus sp nov and the non-human primate-associated Staphylococcus schweitzeri sp nov.

Steven YC Tong, Frieder Schaumburg, Matthew J Ellington, Jukka Corander, Bruno Pichon, Fabian Leendertz, Stephen D Bentley, Julian Parkhill, Deborah C Holt, Georg Peters, Philip M Giffard

Journal article  |  2015  |  International Journal of Systematic and Evolutionary Microbiology

Genome sequencing defines phylogeny and spread of methicillin-resistant Staphylococcus aureus in a high transmission setting

Steven YC Tong, Matthew TG Holden, Emma K Nickerson, Ben S Cooper, Claudio U Koeser, Anne Cori, Thibaut Jombart, Simon Cauchemez, Christophe Fraser, Vanaporn Wuthiekanun, Janjira Thaipadungpanit, Maliwan Hongsuwan, Nicholas P Day, Direk Limmathurotsakul, Julian Parkhill, Sharon J Peacock

Journal article  |  2015  |  Genome Research

The microbiology of impetigo in Indigenous children: associations between Streptococcus pyogenes, Staphylococcus aureus, scabies, and nasal carriage

Asha C Bowen, Steven YC Tong, Mark D Chatfield, Jonathan R Carapetis

Journal article  |  2014  |  BMC Infectious Diseases

Short-course oral co-trimoxazole versus intramuscular benzathine benzylpenicillin for impetigo in a highly endemic region: an open-label, randomised, controlled, non-inferiority trial

Asha C Bowen, Steven YC Tong, Ross M Andrews, Irene M O'Meara, Malcolm I McDonald, Mark D Chatfield, Bart J Currie, Jonathan R Carapetis

Journal article  |  2014  |  The Lancet

Invasive Staphylococcus aureus Infections in Children in Tropical Northern Australia.

Daniel Engelman, Alexandra Hofer, Joshua S Davis, Jonathan R Carapetis, Robert W Baird, Philip M Giffard, Deborah C Holt, Steven YC Tong

Journal article  |  2014  |  Journal of the Pediatric Infectious Diseases Society

BACKGROUND: Despite a high burden of staphylococcal skin disease in children and high incidence of Staphylococcus aureus bacteremi..

Standardising and Assessing Digital Images for Use in Clinical Trials: A Practical, Reproducible Method That Blinds the Assessor to Treatment Allocation

Asha C Bowen, Kara Burns, Steven YC Tong, Ross M Andrews, Robyn Liddle, Irene M O'Meara, Darren W Westphal, Jonathan R Carapetis

Journal article  |  2014  |  PLoS ONE

Characterization of a Novel Thermostable Nuclease Homolog (Nuc(M)) in a Highly Divergent Staphylococcus aureus Clade

Frieder Schaumburg, Maude Pauly, Grit Schubert, Adebayo Shittu, Steven Tong, Fabian Leendertz, Georg Peters, Karsten Becker

Journal article  |  2014  |  Journal of Clinical Microbiology

Hepatocellular carcinoma in Australia's Northern Territory: high incidence and poor outcome

Christopher Parker, Steven YC Tong, Karen Dempsey, John Condon, Suresh K Sharma, John WC Chen, William Sievert, Joshua S Davis

Journal article  |  2014  |  Medical Journal of Australia

What do infectious diseases physicians do? A 2-week snapshot of inpatient consultative activities across Australia, New Zealand and Singapore

PR Ingram, AC Cheng, RJ Murray, CC Blyth, T Walls, DA Fisher, JS Davis

Journal article  |  2014  |  Clinical Microbiology and Infection

Multisite Direct Determination of the Potential for Environmental Contamination of Urine Samples Used for Diagnosis of Sexually Transmitted Infections.

Patiyan Andersson, Steven YC Tong, Rachael A Lilliebridge, Nicole C Brenner, Louise M Martin, Emma Spencer, Jennifer Delima, Gurmeet Singh, Frances McCann, Carolyn Hudson, Tracy Johns, Philip M Giffard

Journal article  |  2014  |  Journal of the Pediatric Infectious Diseases Society

BACKGROUND: The detection of a sexually transmitted infection (STI) agent in a urine specimen from a young child is regarded as an..

VANCOMYCIN DOSING NOMOGRAM FOR HAEMODIALYSIS PATIENTS

Cameron J Jeremiah, Carly Wills, Angela Bayly, Greg J Perry, Joshua S Davis, Steven Y Tong, Bart J Currie

Journal article  |  2014  |  Nephrology

Molecular Virology of Hepatitis B Virus, Sub-Genotype C4 in Northern Australian Indigenous Populations

M Littlejohn, J Davies, L Yuen, R Edwards, T Sozzi, K Jackson, B Cowie, S Tong, J Davis, S Locarnini

Journal article  |  2014  |  Journal of Medical Virology

The clinical and molecular epidemiology of Staphylococcus aureus infections in Fiji

Adam Jenney, Deborah Holt, Roselyn Ritika, Paul Southwell, Shalini Pravin, Eka Buadromo, Jonathan Carapetis, Steven Tong, Andrew Steer

Journal article  |  2014  |  BMC Infectious Diseases

Preexisting CD8 T-cell immunity to the H7N9 influenza a virus varies across ethnicities

S Quiñones-Parra, E Grant, L Loh, THO Nguyen, KA Campbell, SYC Tong, A Miller, PC Doherty, D Vijaykrishna, J Rossjohn, S Gras, K Kedzierska

Journal article  |  2014  |  Proceedings of the National Academy of Sciences of the United States of America

Preexisting CD8( ) T-cell immunity to the H7N9 influenza A virus varies across ethnicities

Sergio Quinones-Parra, Emma Grant, Liyen Loh, Thi HO Nguyen, Kristy-Anne Campbell, Steven YC Tong, Adrian Miller, Peter C Doherty, Dhanasekaran Vijaykrishna, Jamie Rossjohn, Stephanie Gras, Katherine Kedzierska

Journal article  |  2014  |  Proceedings of the National Academy of Sciences of the United States of America

Corrections to Efficacy of RTS,S malaria vaccines: Individual-participant pooled analysis of phase 2 data. [Lancet Infect Dis 13 319-27(2013)]

SYC Tong, AM Kearns

Journal article  |  2013  |  The Lancet Infectious Diseases

A Novel Clinical Grading Scale to Guide the Management of Crusted Scabies

Joshua S Davis, Steven McGloughlin, Steven YC Tong, Shelley F Walton, Bart J Currie

Journal article  |  2013  |  PLoS Neglected Tropical Diseases

Community-associated MRSA from the Indian subcontinent

Steven YC Tong, Angela M Kearns

Journal article  |  2013  |  The Lancet Infectious Diseases

Virulence of Endemic Nonpigmented Northern Australian Staphylococcus aureus Clone (Clonal Complex 75, S-argenteus) Is Not Augmented by Staphyloxanthin

Steven YC Tong, Batu K Sharma-Kuinkel, Joshua T Thaden, Adeline R Whitney, Soo-Jin Yang, Nagendra N Mishra, Thomas Rude, Rachael A Lilliebridge, Maria A Selim, Sun Hee Ahn, Deborah C Holt, Philip M Giffard, Arnold S Bayer, Frank R DeLeo, Vance G Fowler

Journal article  |  2013  |  The Journal of Infectious Diseases

The molecular epidemiology of hepatitis B in the Indigenous people of northern Australia

Jane Davies, Margaret Littlejohn, Stephen A Locarnini, Sarah Whiting, Krispin Hajkowicz, Benjamin C Cowie, David S Bowden, Steven YC Tong, Joshua S Davis

Journal article  |  2013  |  Journal of Gastroenterology and Hepatology

Genomic Insights to Control the Emergence of Vancomycin-Resistant Enterococci

Benjamin P Howden, Kathryn E Holt, Margaret MC Lam, Torsten Seemann, Susan Ballard, Geoffrey W Coombs, Steven YC Tong, M Lindsay Grayson, Paul DR Johnson, Timothy P Stinear

Journal article  |  2013  |  MBIO

Comparison of three methods for the recovery of skin pathogens from impetigo swabs collected in a remote community of Northern Territory, Australia

Asha C Bowen, Steven YC Tong, Mark D Chatfield, Ross M Andrews, Jonathan R Carapetis

Journal article  |  2013  |  Transactions of The Royal Society of Tropical Medicine and Hygiene

Hepatitis D is rare or non-existent in hepatitis B virus-infected Indigenous Australians in the Northern Territory

Jane Davies, Steven YC Tong, Joshua S Davis

Journal article  |  2013  |  Australian and New Zealand Journal of Public Health

Reply to "Susceptibility of Streptococcus pyogenes to Trimethoprim-Sulfamethoxazole"

Asha C Bowen, Steven YC Tong, Jonathan R Carapetis

Journal article  |  2013  |  Journal of Clinical Microbiology

Community-associated meticillin-resistant Staphylococcus aureus carriage in hospitalized patients in tropical northern Australia

L Brennan, RA Lilliebridge, AC Cheng, PM Giffard, BJ Currie, SYC Tong

Journal article  |  2013  |  Journal of Hospital Infection

Genomic polish for shoe-leather epidemiology

Steven YC Tong

Journal article  |  2013  |  Nature Reviews Microbiology

Is Streptococcus pyogenes Resistant or Susceptible to Trimethoprim-Sulfamethoxazole?

Asha C Bowen, Rachael A Lilliebridge, Steven YC Tong, Robert W Baird, Peter Ward, Malcolm I McDonald, Bart J Currie, Jonathan R Carapetis

Journal article  |  2012  |  Journal of Clinical Microbiology

Microbiological Applications of High-Resolution Melting Analysis

Steven YC Tong, Philip M Giffard

Journal article  |  2012  |  Journal of Clinical Microbiology

Impact of ethnicity and socio-economic status on Staphylococcus aureus bacteremia incidence and mortality: a heavy burden in Indigenous Australians

Steven YC Tong, Sebastian J van Hal, Lloyd Einsiedel, Bart J Currie, John D Turnidge

Journal article  |  2012  |  BMC Infectious Diseases

Impact of Results of a Rapid Staphylococcus aureus Diagnostic Test on Prescribing of Antibiotics for Patients with Clustered Gram-Positive Cocci in Blood Cultures

Jane Davies, Claire L Gordon, Steven YC Tong, Robert W Baird, Joshua S Davis

Journal article  |  2012  |  Journal of Clinical Microbiology

Panton-Valentine Leukocidin Is Not the Primary Determinant of Outcome for Staphylococcus aureus Skin Infections: Evaluation from the CANVAS Studies

Amy Tong, Steven YC Tong, Yurong Zhang, Supaporn Lamlertthon, Batu K Sharma-Kuinkel, Thomas Rude, Sun Hee Ahn, Felicia Ruffin, Lily Llorens, Ganesh Tamarana, Donald Biek, Ian Critchley, Vance G Fowler

Journal article  |  2012  |  PLoS ONE

EPIDEMIOLOGY OF HEPATOCELLULAR CARCINOMA IN THE TOP END

C Parker, J Davis, W Sievert, S Tong, S Condon, K Dempsey

Conference Proceedings  |  2012  |  INTERNAL MEDICINE JOURNAL

Murray Valley encephalitis: a review of clinical features, diagnosis and treatment

James Knox, Raquel U Cowan, Joseph S Doyle, Matthew K Ligtermoet, John S Archer, James NC Burrow, Steven YC Tong, Bart J Currie, John S Mackenzie, David W Smith, Mike Catton, Rodney J Moran, Craig A Aboltins, Jack S Richards

Journal article  |  2012  |  MEDICAL JOURNAL OF AUSTRALIA

Minim Typing - A Rapid and Low Cost MLST Based Typing Tool for Klebsiella pneumoniae

Patiyan Andersson, Steven YC Tong, Jan M Bell, John D Turnidge, Philip M Giffard

Journal article  |  2012  |  PLoS ONE

Colonization, pathogenicity, host susceptibility, and therapeutics for Staphylococcus aureus: what is the clinical relevance?

Steven YC Tong, Luke F Chen, Vance G Fowler

Journal article  |  2012  |  Seminars in Immunopathology

Presence of Genes Encoding Panton-Valentine Leukocidin Is Not the Primary Determinant of Outcome in Patients with Hospital-Acquired Pneumonia Due to Staphylococcus aureus

Batu K Sharma-Kuinkel, Sun H Ahn, Thomas H Rude, Yurong Zhang, Steven YC Tong, Felicia Ruffin, Fredric C Genter, Kevin R Braughton, Frank R DeLeo, Steven L Barriere, Vance G Fowler

Journal article  |  2012  |  Journal of Clinical Microbiology

High-Resolution Melting Genotyping of Enterococcus faecium Based on Multilocus Sequence Typing Derived Single Nucleotide Polymorphisms

Steven YC Tong, Shirley Xie, Leisha J Richardson, Susan A Ballard, Farshid Dakh, Elizabeth A Grabsch, M Lindsay Grayson, Benjamin P Howden, Paul DR Johnson, Philip M Giffard

Journal article  |  2011  |  PLoS ONE

Preliminary validation of a novel high-resolution melt-based typing method based on the multilocus sequence typing scheme of Streptococcus pyogenes

LJ Richardson, SYC Tong, RJ Towers, F Huygens, K McGregor, PK Fagan, BJ Currie, JR Carapetis, PM Giffard

Journal article  |  2011  |  Clinical Microbiology and Infection

Rapid Detection of the H275Y Oseltamivir Resistance Mutation in Influenza A/H1N1 2009 by Single Base Pair RT-PCR and High-Resolution Melting

Steven YC Tong, Farshid Dakh, Aeron C Hurt, Yi-Mo Deng, Kevin Freeman, Peter K Fagan, Ian G Barr, Philip M Giffard

Journal article  |  2011  |  PLoS ONE

The Utility of High-Resolution Melting Analysis of SNP Nucleated PCR Amplicons-An MLST Based Staphylococcus aureus Typing Scheme

Rachael A Lilliebridge, Steven YC Tong, Philip M Giffard, Deborah C Holt

Journal article  |  2011  |  PLoS ONE

A Very Early-Branching Staphylococcus aureus Lineage Lacking the Carotenoid Pigment Staphyloxanthin

Deborah C Holt, Matthew TG Holden, Steven YC Tong, Santiago Castillo-Ramirez, Louise Clarke, Michael A Quail, Bart J Currie, Julian Parkhill, Stephen D Bentley, Edward J Feil, Philip M Giffard

Journal article  |  2011  |  Genome Biology and Evolution

Community-associated Methicillin-resistant Staphylococcus aureus Skin Infections in the Tropics

Steven YC Tong, Andrew C Steer, Adam W Jenney, Jonathan R Carapetis

Journal article  |  2011  |  Dermatologic Clinics

Clinical Correlates of Panton-Valentine Leukocidin (PVL), PVL Isoforms, and Clonal Complex in the Staphylococcus aureus Population of Northern Australia

Steven YC Tong, Rachael A Lilliebridge, Emma J Bishop, Allen C Cheng, Deborah C Holt, Malcolm I McDonald, Philip M Giffard, Bart J Currie, Craig S Boutlis

Journal article  |  2010  |  The Journal of Infectious Diseases

Rapid detection of H and R Panton-Valentine leukocidin isofonns in Staphylococcus aureus by high-resolution melting analysis

Steven YC Tong, Rachael A Lilliebridge, Deborah C Holt, Geoffrey W Coombs, Bart J Currie, Philip M Giffard

Journal article  |  2010  |  Diagnostic Microbiology and Infectious Disease

Pulmonary imaging of pandemic influenza H1N1 infection: relationship between clinical presentation and disease burden on chest radiography and CT.

L Abbo, A Quartin, MI Morris, G Saigal, E Ariza-Heredia, P Mariani, O Rodriguez, LS Muñoz-Price, M Ferrada, E Ramee, MI Rosas, IA Gonzalez, J Fishman

Journal article  |  2010  |  The British Journal of Radiology

The potential for pulmonary involvement among patients presenting with novel swine-origin influenza A (H1N1) is high. To investiga..

Disproportionate impact of pandemic (H1N1) 2009 influenza on Indigenous people in the Top End of Australia's Northern Territory

Shaun M Flint, Joshua S Davis, Jiunn-Yih Su, Erin P Oliver-Landry, Benjamin A Rogers, Aaron Goldstein, Jane H Thomas, Uma Parameswaran, Colin Bigham, Kevin Freeman, Paul Goldrick, Steven YC Tong

Journal article  |  2010  |  Medical Journal of Australia

Community-acquired, Methicillin-resistant, Staphylococcus aureus

S Tong

Conference Proceedings  |  2010  |  AUSTRALASIAN JOURNAL OF DERMATOLOGY

Trimethopim-sulfamethoxazole compared with benzathine penicillin for treatment of impetigo in Aboriginal children: A pilot randomised controlled trial

Steven YC Tong, Ross M Andrews, Therese Kearns, Rosalyn Gundjirryirr, Malcolm I McDonald, Bart J Currie, Jonathan R Carapetis

Journal article  |  2010  |  Journal of Paediatrics and Child Health

Campylobacter jejuni and Campylobacter coli Genotyping by High-Resolution Melting Analysis of a flaA Fragment

Shreema Merchant-Patel, Patrick J Blackall, Jillian Templeton, Erin P Price, Steven YC Tong, Flavia Huygens, Philip M Giffard

Journal article  |  2010  |  Applied and Environmental Microbiology

High-resolution melting analysis of the spa locus reveals significant diversity within sequence type 93 methicillin-resistant Staphylococcus aureus from northern Australia

SYC Tong, RA Lilliebridge, DC Holt, MI McDonald, BJ Currie, PM Giffard

Journal article  |  2009  |  Clinical Microbiology and Infection

Phylogenetically Distinct Staphylococcus aureus Lineage Prevalent among Indigenous Communities in Northern Australia

Jacklyn WS Ng, Deborah C Holt, Rachael A Lilliebridge, Alex J Stephens, Flavia Huygens, Steven YC Tong, Bart J Currie, Philip M Giffard

Journal article  |  2009  |  Journal of Clinical Microbiology

Analysis of bla(SHV) Codon 238 and 240 Allele Mixtures Using Sybr Green High-Resolution Melting Analysis

Patiyan Andersson, Tegan Harris, Steven YC Tong, Philip M Giffard

Journal article  |  2009  |  Antimicrobial Agents and Chemotherapy

Community-Associated Strains of Methicillin-Resistant Staphylococcus aureus and Methicillin-Susceptible S. aureus in Indigenous Northern Australia: Epidemiology and Outcomes

Steven YC Tong, Emma J Bishop, Rachael A Lilliebridge, Allen C Cheng, Zornitsa Spasova-Penkova, Deborah C Holt, Philip M Giffard, Malcolm I McDonald, Bart J Currie, Craig S Boutlis

Journal article  |  2009  |  The Journal of Infectious Diseases

The authors reply

LS Munoz-Price, RA Weinstein

Journal article  |  2008  |  New England Journal of Medicine

Global implications of the emergence of community-associated methicillin-resistant Staphylococcus aureus in indigenous populations

Steven YC Tong, Malcolm I McDonald, Deborah C Holt, Bart J Currie

Journal article  |  2008  |  Clinical Infectious Diseases

Fatal community-associated methicillin-resistant Staphylococcus aureus pneumonia after influenza

Steven YC Tong, Nicholas M Anstey, Gary D Lum, Rachael A Lilliebridge, Dianne P Stephens, Bart J Currie

Journal article  |  2008  |  Medical Journal of Australia

Breakthrough Scedosporium prolificans infection while receiving voriconazole prophylaxis in an allogeneic stem cell transplant recipient.

SYC Tong, AY Peleg, J Yoong, R Handke, J Szer, M Slavin

Journal article  |  2007  |  Transplant Infectious Disease

Breakthrough invasive fungal infections among patients with hematologic malignancies receiving voriconazole are being reported wit..

Illness in travelers visiting friends and relatives: A review of the GeoSentinel surveillance network

Karin Leder, Steven Tong, Leisa Weld, Kevin C Kain, Annelies Wilder-Smith, Frank Von Sonnenburg, Jim Black, Graham V Brown, Joseph Torresi

Journal article  |  2006  |  Clinical Infectious Diseases

A pox on the heart: five cases of cardiovascular syphilis

SYC Tong, H Haqqani, AC Street

Journal article  |  2006  |  Medical Journal of Australia

The role of menopause in the development of chronic mountain sickness.

F León-Velarde, MA Ramos, JA Hernández, D De Idiáquez, LS Muñoz, A Gaffo, S Córdova, D Durand, C Monge

Journal article  |  1997  |  American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

The objective of this study was to investigate the role of menopause in the appearance of the physiopathological sequence that lea..

Prevalence of late orchidopexy is consistent with some undescended testes being acquired.

KM Donaldson, SY Tong, JM Hutson

Conference Proceedings  |  1996  |  The Indian Journal of Pediatrics

To diagnose the incidence of orchidopexy versus age over a 15-year period, a study was conducted of all patients discharged from a..

Does testosterone diffuse down the wolffian duct during sexual differentiation?

SYC Tong, JM Hutson, LM Watts

Journal article  |  1996  |  Journal of Urology

Does Testosterone Diffuse Down the Wolffian Duct During Sexual Differentiation?

Steven YC Tong, John M Hutson, Lisa M Watts

Journal article  |  1996  |  The Journal of Urology

Morphometric study of the gubernaculum in male estrogen receptor mutant mice

KM Donaldson, SYC Tong, T Washburn, DB Lubahn, EM Eddy, JM Hutson, KS Korach

Journal article  |  1996  |  Journal of Andrology

When is hypospadias not hypospadias?

SYC Tong, K Donaldson, JM Hutson

Journal article  |  1996  |  Medical Journal of Australia

Indigenous Australian household structure: a simple data collection tool and implications for close contact transmission of communicable diseases

Thiripura Vino, Gurmeet R Singh, Belinda Davison, Patricia T Campbell, Michael Lydeamore, Andrew Robinson, Jodie McVernon, Steven YC Tong, Nicholas Geard

Journal article

Households are an important location for the transmission of communicable diseases. Social contact between household members is ty..

Breadth of concomitant immune responses underpinning viral clearance and patient recovery in a non-severe case of COVID-19

Irani Thevarajan, Thi HO Nguyen, Marios Koutsakos, Julian Druce, Leon Caly, Carolien E van de Sandt, Xiaoxiao Jia, Suellen Nicholson, Mike Catton, Benjamin Cowie, Steven Tong, Sharon Lewin, Katherine Kedzierska

Journal article

We report the kinetics of the immune response in relation to clinical and virological features of a patient with mild-to-moderate ..