Jason Tye-Din

Longitudinal assessment of the common sense model before and during the COVID-19 pandemic: A large coeliac disease cohort study

SP Möller, P Apputhurai, JA Tye-Din, SR Knowles

Journal article  |  2022  |  Journal of Psychosomatic Research

Objective: Psychosocial factors likely play a substantial role in the well-being of those living with coeliac disease, especially ..

Hydroxychloroquine inhibits the mitochondrial antioxidant system in activated T cells.

Man Lyang Kim, Melinda Y Hardy, Laura E Edgington-Mitchell, Sri H Ramarathinam, Shan Zou Chung, Amy K Russell, Iain Currie, Brad E Sleebs, Anthony W Purcell, Jason A Tye-Din, Ian P Wicks

Journal article  |  2021  |  iScience

Although hydroxychloroquine (HCQ) has long been used to treat autoimmune diseases, its mechanism of action remains poorly understo..

Quality of life in coeliac disease: relationship between psychosocial processes and quality of life in a sample of 1697 adults living with coeliac disease.

Stephan P Möller, Pragalathan Apputhurai, Jason A Tye-Din, Simon R Knowles

Journal article  |  2021  |  J Psychosom Res

BACKGROUND: Coeliac disease is a chronic gastrointestinal condition associated with an increased risk of psychiatric comorbidity, ..

Systematic review: Exploration of the impact of psychosocial factors on quality of life in adults living with coeliac disease.

Stephan P Möller, Bree Hayes, Helen Wilding, Pragalathan Apputhurai, Jason A Tye-Din, Simon R Knowles

Journal article  |  2021  |  J Psychosom Res

BACKGROUND: Individuals living with coeliac disease generally experience a remission of symptoms after adopting the gluten-free di..

A Sensitive Whole Blood Assay Detects Antigen-Stimulated Cytokine Release From CD4 T Cells and Facilitates Immunomonitoring in a Phase 2 Clinical Trial of Nexvax2 in Coeliac Disease

Melinda Y Hardy, Gautam Goel, Amy K Russell, Swee Lin G Chen Yi Mei, Gregor JE Brown, Suyue Wang, Evan Szymczak, Ruan Zhang, Kaela E Goldstein, Kristin M Neff, Leslie J Williams, Kenneth E Truitt, John L Dzuris, Jason A Tye-Din, Robert P Anderson

Journal article  |  2021  |  FRONTIERS IN IMMUNOLOGY

Improved blood tests assessing the functional status of rare gluten-specific CD4+ T cells are needed to effectively monitor experi..

Risk perception and knowledge of COVID-19 in patients with celiac disease

Jamie Zhen, Juan Pablo Stefanolo, Maria de la Paz Temprano, Caroline L Seiler, Alberto Caminero, Enrique De-Madaria, Miguel Montoro Huguet, Vivas Santiago, Sonia Isabel Niveloni, Edgardo Gustavo Smecuol, Luis Uzcanga Dominguez, Elena Trucco, Virginia Lopez, Carolina Olano, Pasquale Mansueto, Antonio Carroccio, Peter H Green, Donald Duerksen, Andrew S Day, Jason A Tye-Din, et al.

Journal article  |  2021  |  WORLD JOURNAL OF GASTROENTEROLOGY

BACKGROUND: We recently demonstrated that the odds of contracting coronavirus disease 2019 (COVID-19) in patients with celiac dise..

Whole blood interleukin-2 release test to detect and characterize rare circulating gluten-specific T cell responses in coeliac disease

RP Anderson, G Goel, MY Hardy, AR Russell, S Wang, E Szymczak, R Zhang, KE Goldstein, M Neff, KE Truitt, LJ Williams, JL Dzuris, JA Tye-Din

Journal article  |  2021  |  CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Whole blood cytokine release assays (CRA) assessing cellular immunity to gluten could simplify the diagnosis and monitoring of coe..

The Risk of Contracting COVID-19 Is Not Increased in Patients With Celiac Disease

Jamie Zhen, Juan Pablo Stefanolo, Maria de la Paz Temprano, Sebastian Tedesco, Caroline Seiler, Alberto Fernandez Caminero, Enrique de-Madaria, Miguel Montoro Huguet, Santiago Vivas, Sonia Isabel Niveloni, Premysl Bercik, Edgardo Smecuol, Luis Uscanga, Elena Trucco, Virginia Lopez, Carolina Olano, Pasquale Mansueto, Antonio Carroccio, Peter HR Green, Andrew Day, et al.

Journal article  |  2021  |  CLINICAL GASTROENTEROLOGY AND HEPATOLOGY

The World Health Organization declared coronavirus disease-2019 (COVID-19) a global pandemic in March 2020. Since then, there are ..

Iron deficiency

Sant-Rayn Pasricha, Jason Tye-Din, Martina U Muckenthaler, Dorine W Swinkels

Journal article  |  2021  |  LANCET

Iron deficiency is one of the leading contributors to the global burden of disease, and particularly affects children, premenopaus..

Patient factors influencing acute gluten reactions and cytokine release in treated coeliac disease.

Jason A Tye-Din, A James M Daveson, Kaela E Goldstein, Holly L Hand, Kristin M Neff, Gautam Goel, Leslie J Williams, Kenneth E Truitt, Robert P Anderson, undefined RESET CeD Study Group

Journal article  |  2020  |  BMC Med

BACKGROUND: Patients with coeliac disease (CD) commonly report a variety of adverse symptoms to gluten, but descriptions of the sy..