Jason Tye-Din

Editorial: inaccuracies in attribution of symptoms due to gluten-not just in those with self-reported noncoeliac gluten sensitivity. Authors' reply

A James M Daveson, Jason A Tye-Din, Robert P Anderson

Journal article  |  2020  |  Alimentary Pharmacology & Therapeutics

Circulating gluten-specific, but not CMV-specific, CD39( ) regulatory T cells have an oligoclonal TCR repertoire

Laura Cook, C Mee Ling Munier, Nabila Seddiki, Melinda Y Hardy, Robert P Anderson, John Zaunders, Jason A Tye-Din, Anthony D Kelleher, David van Bockel

Journal article  |  2020  |  Clinical & Translational Immunology

Objectives: Understanding the T cell receptor (TCR) repertoire of regulatory CD4+ T-cell (Treg) populations is important for strat..

T cell receptor cross-reactivity between gliadin and bacterial peptides in celiac disease

Jan Petersen, Laura Ciacchi, Mai T Tran, Khai Lee Loh, Yvonne Kooy-Winkelaar, Nathan P Croft, Melinda Y Hardy, Zhenjun Chen, James McCluskey, Robert P Anderson, Anthony W Purcell, Jason A Tye-Din, Frits Koning, Hugh H Reid, Jamie Rossjohn

Journal article  |  2019  |  Nature Structural & Molecular Biology

The human leukocyte antigen (HLA) locus is strongly associated with T cell-mediated autoimmune disorders. HLA-DQ2.5-mediated celia..

Masked bolus gluten challenge low in FODMAPs implicates nausea and vomiting as key symptoms associated with immune activation in treated coeliac disease

A James M Daveson, Jason A Tye-Din, Gautam Goel, Kaela E Goldstein, Holly L Hand, Kristin M Neff, Leslie J Williams, Kenneth E Truitt, Robert P Anderson, A Adams, J Andrews, C Behrend, G Brown, S Chen Yi Mei, A Coates, AJM Daveson, A DiMarino, H Ee, D Elliott, R Epstein, et al.

Journal article  |  2019  |  Alimentary Pharmacology & Therapeutics

Update 2020: nomenclature and listing of celiac disease-relevant gluten epitopes recognized by CD4 T cells.

Ludvig M Sollid, Jason A Tye-Din, Shuo-Wang Qiao, Robert P Anderson, Carmen Gianfrani, Frits Koning

Journal article  |  2019  |  Immunogenetics

Celiac disease is caused by an abnormal intestinal T cell response to cereal gluten proteins. The disease has a strong human leuko..

Elevated serum interleukin-2 after gluten correlates with symptoms and is a potential diagnostic biomarker for coeliac disease

Jason A Tye-Din, A James M Daveson, Hooi C Ee, Gautam Goel, James MacDougall, Sarah Acaster, Kaela E Goldstein, John L Dzuris, Kristin M Neff, Kenneth E Truitt, Robert P Anderson

Journal article  |  2019  |  Alimentary Pharmacology & Therapeutics

Serum cytokines elevated during gluten-mediated cytokine release in coeliac disease

G Goel, AJM Daveson, CE Hooi, JA Tye-Din, S Wang, E Szymczak, LJ Williams, JL Dzuris, KM Neff, KE Truitt, RP Anderson

Journal article  |  2019  |  Clinical & Experimental Immunology

Cytokine release after gluten ingestion differentiates coeliac disease from self-reported gluten sensitivity

Jason A Tye-Din, Gry Skodje, Vikas K Sarna, John L Dzuris, Amy K Russell, Gautam Goel, Suyue Wang, Kaela E Goldstein, Leslie J Williams, Ludvig M Sollid, Knut EA Lundin, Robert P Anderson

Journal article  |  2019  |  United European Gastroenterology Journal

Characterisation of clinical and immune reactivity to barley and rye ingestion in children with coeliac disease.

Melinda Y Hardy, Amy K Russell, Catherine Pizzey, Claerwen M Jones, Katherine A Watson, Nicole L La Gruta, Donald J Cameron, Jason A Tye-Din

Journal article  |  2019  |  Gut

OBJECTIVE: Barley and rye are major components of the Western diet, and historic feeding studies indicate that they cause clinical..

Cytokine release and gastrointestinal symptoms after gluten challenge in celiac disease

Gautam Goel, Jason A Tye-Din, Shuo-Wang Qiao, Amy K Russell, Toufic Mayassi, Cezary Ciszewski, Vikas K Sarna, Suyue Wang, Kaela E Goldstein, John L Dzuris, Leslie J Williams, Ramnik J Xavier, Knut EA Lundin, Bana Jabri, Ludvig M Sollid, Robert P Anderson

Journal article  |  2019  |  Science Advances

Preparation and Characterization of Avenin-Enriched Oat Protein by Chill Precipitation for Feeding Trials in Celiac Disease.

Greg Tanner, Angéla Juhász, Christakis George Florides, Mitchell Nye-Wood, Frank Békés, Michelle L Colgrave, Amy K Russell, Melinda Y Hardy, Jason A Tye-Din

Journal article  |  2019  |  Frontiers in Nutrition

The safety of oats for people with celiac disease remains unresolved. While oats have attractive nutritional properties that can i..

Celiac Disease: A Review of Current Concepts in Pathogenesis, Prevention, and Novel Therapies

Jason A Tye-Din, Heather J Galipeau, Daniel Agardh

Journal article  |  2018  |  Frontiers in Pediatrics

Gluten in "gluten-free" manufactured foods in Australia: a cross-sectional study

Emma P Halmos, Dean Clarke, Catherine Pizzey, Jason A Tye-Din

Journal article  |  2018  |  Medical Journal of Australia

High rates of variation in HLA-DQ2/DQ8 testing for coeliac disease: results from an RCPAQAP pilot program

Martin Patrick Horan, Sze Yee Chai, Nalishia Munusamy, Kwang Hong Tay, Louise Wienholt, Jason A Tye-Din, James Daveson, Michael Varney, Tony Badrick

Journal article  |  2018  |  Journal of Clinical Pathology

T cells in coeliac disease: a rational target for diagnosis and therapy

Melinda Y Hardy, Jason A Tye-Din

Journal article  |  2018  |  Nature Reviews Gastroenterology & Hepatology

Genome mapping of seed-borne allergens and immunoresponsive proteins in wheat

Angela Juhasz, Tatiana Belova, Chris G Florides, Csaba Maulis, Iris Fischer, Gyongyver Gell, Zsfia Birinyi, Jamie Ong, Gabriel Keeble-Gagnere, Amudha Maharajan, Wujun Ma, Peter Gibson, Jizeng Jia, Daniel Lang, Klaus FX Mayer, Manuel Spannagl, Jason A Tye-Din, Rudi Appels, Odd-Arne Olsen

Journal article  |  2018  |  Science Advances

Gluten in "gluten-free" food from food outlets in Melbourne: a cross-sectional study

Emma P Halmos, Catherine A Di Bella, Russell Webster, Minfeng Deng, Jason A Tye-Din

Journal article  |  2018  |  Medical Journal of Australia

Food knowledge and psychological state predict adherence to a gluten-free diet in a survey of 5310 Australians and New Zealanders with coeliac disease

EP Halmos, M Deng, SR Knowles, K Sainsbury, B Mullan, JA Tye-Din

Journal article  |  2018  |  Alimentary Pharmacology & Therapeutics

Maintenance of a gluten free diet in coeliac disease: The roles of self-regulation, habit, psychological resources, motivation, support, and goal priority

Kirby Sainsbury, Emma P Halmos, Simon Knowles, Barbara Mullan, Jason A Tye-Din

Journal article  |  2018  |  Appetite

Rapid, Loop-Mediated Isothermal Amplification Detection of Celiac Disease Risk Alleles

Michael Erlichster, Jason A Tye-Din, Michael D Varney, Efstratios Skafidas, Patrick Kwan

Journal article  |  2018  |  The Journal of Molecular Diagnostics

Resolving incomplete single nucleotide polymorphism tagging of HLA-DQ2.2 for coeliac disease genotyping using digital droplet PCR

MY Hardy, N Ontiveros, MD Varney, JA Tye-Din

Journal article  |  2018  |  HLA

Interpreting tests for coeliac disease: Tips, pitfalls and updates

Jason Tye-Din

Journal article  |  2018  |  Australian Journal of General Practice

BACKGROUND: Coeliac disease is one of most prevalent autoimmune illnesses encountered in general practice, and general practitione..

Circulating gluten-specific FOXP3( )CD39( ) regulatory T cells have impaired suppressive function in patients with celiac disease

Laura Cook, C Mee Ling Munier, Nabila Seddiki, David van Bockel, Noe Ontiveros, Melinda Y Hardy, Jana K Gillies, Megan K Levings, Hugh H Reid, Jan Petersen, Jamie Rossjohn, Robert P Anderson, John J Zaunders, Jason A Tye-Din, Anthony D Kelleher

Journal article  |  2017  |  Journal of Allergy and Clinical Immunology

Editorial: a novel approach to monitor mucosal healing in coeliac disease-as simple as shifting goalposts?

JA Tye-Din

Journal article  |  2017  |  Alimentary Pharmacology & Therapeutics

Discrepancies in genetic testing results for coeliac disease: Call for standardised testing and reporting

AJM Daveson, M Varney, KE Jackson, JA Tye-Din

Journal article  |  2017  |  Medical Journal of Australia

Discrepancies in genetic testing results for coeliac disease: call for standardised testing and reporting

A James M Daveson, Michael Varney, Kate E Jackson, Jason A Tye-Din

Journal article  |  2017  |  Medical Journal of Australia

The practice and perception of precautionary allergen labelling by the Australasian food manufacturing industry

GA Zurzolo, RL Peters, JJ Koplin, M de Courten, ML Mathai, JA Tye-Din, MLK Tang, DE Campbell, A-L Ponsonby, SL Prescott, L Gurrin, SC Dharmage, KJ Allen

Journal article  |  2017  |  Clinical & Experimental Allergy

Epitope-specific immunotherapy targeting CD4-positive T cells in coeliac disease: two randomised, double-blind, placebo-controlled phase 1 studies

Gautam Goel, Tim King, A James Daveson, Jane M Andrews, Janakan Krishnarajah, Richard Krause, Gregor JE Brown, Ronald Fogel, Charles F Barish, Roger Epstein, Timothy P Kinney, Philip B Miner, Jason A Tye-Din, Adam Girardin, Juha Taavela, Alina Popp, John Sidney, Markku Maki, Kaela E Goldstein, Patrick H Griffin, et al.

Journal article  |  2017  |  The Lancet Gastroenterology & Hepatology

Coeliac disease: a unique model for investigating broken tolerance in autoimmunity

Melinda Y Hardy, Jason A Tye-Din

Journal article  |  2016  |  Clinical & Translational Immunology

Duodenal Bacteria From Patients With Celiac Disease and Healthy Subjects Distinctly Affect Gluten Breakdown and Immunogenicity

Alberto Caminero, Heather J Galipeau, Justin L McCarville, Chad W Johnston, Steve P Bernier, Amy K Russell, Jennifer Jury, Alexandra R Herran, Javier Casqueiro, Jason A Tye-Din, Michael G Surette, Nathan A Magarvey, Detlef Schuppan, Elena F Verdu

Journal article  |  2016  |  Gastroenterology

Validation of a Scoring System to Predict Microscopic Colitis in a Cohort of Patients With Chronic Diarrhea Reply

John S Kane, Olorunda Rotimi, Simon M Everett, Alexander C Ford

Journal article  |  2016  |  Clinical Gastroenterology and Hepatology

Age-Related Immunoreactivity to Gluten Peptides in Celiac Disease Reply

Melinda Y Hardy, Robert P Anderson, Jason A Tye-Din

Journal article  |  2016  |  Gastroenterology

Consistency in Polyclonal T-cell Responses to Gluten Between Children and Adults With Celiac Disease

Melinda Y Hardy, Adam Girardin, Catherine Pizzey, Donald J Cameron, Katherine A Watson, Stefania Picascia, Renata Auricchio, Luigi Greco, Carmen Gianfrani, Nicole L La Gruta, Robert P Anderson, Jason A Tye-Din

Journal article  |  2015  |  Gastroenterology

Genomic prediction of celiac disease targeting HLA-positive individuals

Gad Abraham, Alexia Rohmer, Jason A Tye-Din, Michael Inouye

Journal article  |  2015  |  Genome Medicine

Point-of-care testing for coeliac disease antibodies - what is the evidence?

Evan D Newnham, Jason A Tye-Din

Journal article  |  2015  |  The Medical Journal of Australia

Appropriate clinical use of human leukocyte antigen typing for coeliac disease: an Australasian perspective

JA Tye-Din, DJS Cameron, AJ Daveson, AS Day, P Dellsperger, C Hogan, ED Newnham, SJ Shepherd, RH Steele, L Wienholt, MD Varney

Journal article  |  2015  |  Internal Medicine Journal

Ingestion of oats and barley in patients with celiac disease mobilizes cross-reactive T cells activated by avenin peptides and immuno-dominant hordein peptides

Melinda Y Hardy, Jason A Tye-Din, Jessica A Stewart, Frederike Schmitz, Nadine L Dudek, Iresha Hanchapola, Anthony W Purcell, Robert P Anderson

Journal article  |  2015  |  Journal of Autoimmunity

Ex-vivo whole blood secretion of interferon (IFN)-gamma and IFN-gamma-inducible protein-10 measured by enzyme- linked immunosorbent assay are as sensitive as IFN-gamma enzyme- linked immunospot for the detection of gluten- reactive T cells in human leucocyte antigen (HLA)- DQ(2.5)( )- associated coeliac disease

N Ontiveros, JA Tye-Din, MY Hardy, RP Anderson

Journal article  |  2014  |  Clinical and Experimental Immunology

Accurate and Robust Genomic Prediction of Celiac Disease Using Statistical Learning

Gad Abraham, Jason A Tye-Din, Oneil G Bhalala, Adam Kowalczyk, Justin Zobel, Michael Inouye

Journal article  |  2014  |  PLoS Genetics

A novel serogenetic approach determines the community prevalence of celiac disease and informs improved diagnostic pathways

Robert P Anderson, Margaret J Henry, Roberta Taylor, Emma L Duncan, Patrick Danoy, Marylia J Costa, Kathryn Addison, Jason A Tye-Din, Mark A Kotowicz, Ross E Knight, Wendy Pollock, Geoffrey C Nicholson, Ban-Hock Toh, Matthew A Brown, Julie A Pasco

Journal article  |  2013  |  BMC Medicine

Biased T Cell Receptor Usage Directed against Human Leukocyte Antigen DQ8-Restricted Gliadin Peptides Is Associated with Celiac Disease

Sophie E Broughton, Jan Petersen, Alex Theodossis, Stephen W Scally, Khai Lee Loh, Allan Thompson, Jeroen van Bergen, Yvonne Kooy-Winkelaar, Kate N Henderson, Travis Beddoe, Jason A Tye-Din, Stuart I Mannering, Anthony W Purcell, James McCluskey, Robert P Anderson, Frits Koning, Hugh H Reid, Jamie Rossjohn

Journal article  |  2012  |  Immunity

For Celiac Disease, Diagnosis Is Not Enough

Peter R Gibson, Susan J Shepherd, Jason A Tye-Din

Journal article  |  2012  |  Clinical Gastroenterology and Hepatology

Dissecting the T-cell response to hordeins in coeliac disease can develop barley with reduced immunotoxicity

GJ Tanner, CA Howitt, RI Forrester, PM Campbell, JA Tye-Din, RP Anderson

Journal article  |  2010  |  Alimentary Pharmacology & Therapeutics

Comprehensive, Quantitative Mapping of T Cell Epitopes in Gluten in Celiac Disease

Jason A Tye-Din, Jessica A Stewart, James A Dromey, Tim Beissbarth, David A van Heel, Arthur Tatham, Kate Henderson, Stuart I Mannering, Carmen Gianfrani, Derek P Jewell, Adrian VS Hill, James McCluskey, Jamie Rossjohn, Robert P Anderson

Journal article  |  2010  |  Science Translational Medicine

Surveillance of FAP: a prospective blinded comparison of capsule endoscopy and other GI imaging to detect small bowel polyps

Paul Tescher, Finlay A Macrae, Tony Speer, Damien Stella, Robert Gibson, Jason A Tye-Din, Geeta Srivatsa, Ian T Jones, Kaye Marion

Journal article  |  2010  |  Hereditary Cancer in Clinical Practice

The effects of ALV003 pre-digestion of gluten on immune response and symptoms in celiac disease in vivo

Jason A Tye-Din, Robert P Anderson, Rosemary A Ffrench, Gregor J Brown, Peter Hodsman, Matthew Siegel, Wendy Botwick, Revati Shreeniwas

Journal article  |  2010  |  Clinical Immunology

Immunopathogenesis of celiac disease.

Jason Tye-Din, Robert Anderson

Journal article  |  2008  |  Current Gastroenterology Reports

Celiac disease is a chronic inflammatory disease caused by dietary gluten that affects 1% of Europeans and North Americans. Gluten..

A structural and immunological basis for the role of human leukocyte antigen DQ8 in celiac disease

Kate N Henderson, Jason A Tye-Din, Hugh H Reid, Zhenjun Chen, Natalie A Borg, Tim Beissbarth, Arthur Tatham, Stuart I Mannering, Anthony W Purcell, Nadine L Dudek, David A van Heel, James McCluskey, Jamie Rossjohn, Robert P Anderson

Journal article  |  2007  |  Immunity

Aspiration in the context of upper gastrointestinal endoscopy

A Thomson, J Tye-Din, S Tonga, J Scott, C Mclaren, P Pavli, F Lomas

Journal article  |  2007  |  Canadian Journal of Gastroenterology

Antagonists and non-toxic variants of the dominant wheat gliadin T cell epitope in coeliac disease

RP Anderson, DA van Heel, JA Tye-Din, DP Jewell, AVS Hill

Journal article  |  2006  |  Gut

T cells in peripheral blood after gluten challenge in coeliac disease

RP Anderson, DA van Heel, JA Tye-Din, M Barnardo, M Salio, DP Jewell, AVS Hill

Journal article  |  2005  |  Gut

A systematic approach for comprehensive T-cell epitope discovery using peptide libraries

T Beissbarth, JA Tye-Din, GK Smyth, TP Speed, RP Anderson

Journal article  |  2005  |  Bioinformatics