Sarah Best

Characterization of a novel human BFL-1-specific monoclonal antibody

Lahiru Gangoda, Charis E Teh, Michael A Dengler, Sarah A Best, Clare E Weeden, Lin Tai, Erinna F Lee, Walter D Fairlie, Kate D Sutherland, Leonard C Harrison, Daniel H Gray, Andreas Strasser, Marco J Herold

Journal article  |  2020  |  Cell Death & Differentiation

Distinct initiating events underpin the immune and metabolic heterogeneity of KRAS-mutant lung adenocarcinoma

Sarah A Best, Sheryl Ding, Ariena Kersbergen, Xueyi Dong, Ji-Ying Song, Yi Xie, Boris Reljic, Kaiming Li, James E Vince, Vivek Rathi, Gavin M Wright, Matthew E Ritchie, Kate D Sutherland

Journal article  |  2019  |  Nature Communications

FGFR3-TACC3 is an oncogenic fusion protein in respiratory epithelium

Sarah A Best, Cassandra R Harapas, Ariena Kersbergen, Vivek Rathi, Marie-Liesse Asselin-Labat, Kate D Sutherland

Journal article  |  2018  |  Oncogene

Lung morphogenesis is orchestrated through Grainyhead-like 2 (Grhl2) transcriptional programs

Ariena Kersbergen, Sarah A Best, Sebastian Dworkin, Casey Ah-Cann, Michael E de Vries, Marie-Liesse Asselin-Labat, Matthew E Ritchie, Stephen M Jane, Kate D Sutherland

Journal article  |  2018  |  Developmental Biology

Interrogating the Metabolic Effects of Keap1 Inactivation in Adenocarcinoma

S Best, S Ding, A Kersbergen, B Reljic, K Sutherland

Conference Proceedings  |  2018  |  Journal of Thoracic Oncology

Synergy between the KEAP1/NRF2 and PI3K Pathways Drives Non-Small-Cell Lung Cancer with an Altered Immune Microenvironment

Sarah A Best, David P De Souza, Ariena Kersbergen, Antonia N Policheni, Saravanan Dayalan, Dedreia Tull, Vivek Rathi, Daniel H Gray, Matthew E Ritchie, Malcolm J McConville, Kate D Sutherland

Journal article  |  2018  |  Cell Metabolism

Combining Cell Type-Restricted Adenoviral Targeting with Immunostaining and Flow Cytometry to Identify Cells-of-Origin of Lung Cancer

Sarah A Best, Ariena Kersbergen, Marie-Liesse Asselin-Labat, Kate D Sutherland

Book Chapter  |  2018  |  Methods in Molecular Biology

"Keaping" a lid on lung cancer: the Keap1-Nrf2 pathway

Sarah A Best, Kate D Sutherland

Journal article  |  2018  |  Cell Cycle

CCAR2 Is Required for Proliferation and Tumor Maintenance in Human Squamous Cell Carcinoma

Sarah A Best, Amy N Nwaobasi, Chrysalyne D Schmults, Matthew R Ramsey

Journal article  |  2017  |  Journal of Investigative Dermatology

Pro-apoptotic Bim suppresses breast tumor cell metastasis and is a target gene of SNAI2

D Merino, SA Best, M-L Asselin-Labat, F Vaillant, B Pal, RA Dickins, RL Anderson, A Strasser, P Bouillet, GJ Lindeman, JE Visvader

Journal article  |  2015  |  Oncogene

Activated Notch counteracts Ikaros tumor suppression in mouse and human T-cell acute lymphoblastic leukemia

MT Witkowski, L Cimmino, Y Hu, T Trimarchi, H Tagoh, MD McKenzie, SA Best, L Tuohey, TA Willson, SL Nutt, M Busslinger, I Aifantis, GK Smyth, RA Dickins

Journal article  |  2015  |  Leukemia

A pooled shRNA screen for regulators of primary mammary stem and progenitor cells identifies roles for Asap1 and Prox1

Julie M Sheridan, Matthew E Ritchie, Sarah A Best, Kun Jiang, Tamara J Beck, Francois Vaillant, Kevin Liu, Ross A Dickins, Gordon K Smyth, Geoffrey J Lindeman, Jane E Visvader

Journal article  |  2015  |  BMC Cancer

EGF-mediated induction of Mcl-1 at the switch to lactation is essential for alveolar cell survival

Nai Yang Fu, Anne C Rios, Bhupinder Pal, Rina Soetanto, Aaron TL Lun, Kevin Liu, Tamara Beck, Sarah A Best, Francois Vaillant, Philippe Bouillet, Andreas Strasser, Thomas Preiss, Gordon K Smyth, Rey J Lindeman, Jane E Visvader

Journal article  |  2015  |  Nature Cell Biology

Runx2 Is a Novel Regulator of Mammary Epithelial Cell Fate in Development and Breast Cancer

Thomas W Owens, Renee L Rogers, Sarah A Best, Anita Ledger, Anne-Marie Mooney, Alison Ferguson, Paul Shore, Alexander Swarbrick, Christopher J Ormandy, Peter T Simpson, Jason S Carroll, Jane E Visvader, Matthew J Naylor

Journal article  |  2014  |  Cancer Research

Dual roles for Id4 in the regulation of estrogen signaling in the mammary gland and ovary

Sarah A Best, Karla J Hutt, Nai Yang Fu, Francois Vaillant, Seng H Liew, Lynne Hartley, Clare L Scott, Geoffrey J Lindeman, Jane E Visvader

Journal article  |  2014  |  Development

Pax5 loss imposes a reversible differentiation block in B-progenitor acute lymphoblastic leukemia

Grace J Liu, Luisa Cimmino, Julian G Jude, Yifang Hu, Matthew T Witkowski, Mark D McKenzie, Mutlu Kartal-Kaess, Sarah A Best, Laura Tuohey, Yang Liao, Wei Shi, Charles G Mullighan, Michael A Farrar, Stephen L Nutt, Gordon K Smyth, Johannes Zuber, Ross A Dickins

Journal article  |  2014  |  Genes & Development