Mariana Del Rosso De Melo

Selective Inhibition of Pre‐Bötzinger Neurons Projecting to the Facial Nucleus Decreases Nasofacial Activity Without Affecting Breathing

Mariana Del Rosso de Melo, Alexander Wykes, David Farmer, Angela Connelly, Jaspreet Bassi, Ross Bathgate, Andrew Allen

Journal article  |  2021  |  The FASEB Journal

Intracranial Pressure During the Development of Renovascular Hypertension

Marcos Vinicius Fernandes, Mariana Rosso Melo, Francesca Elisabeth Mowry, Gabriela Maria Lucera, Mariana Ruiz Lauar, Gustavo Frigieri, Vinicia Campana Biancardi, Jose Menani, Debora Simoes Almeida Colombari, Eduardo Colombari

Journal article  |  2021  |  HYPERTENSION

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Physiological and Transcriptomic Changes in the Hypothalamic-Neurohypophysial System after 24 h of Furosemide-Induced Sodium Depletion

Sabrina G Dutra, Alex Paterson, Livia RN Monteiro, Michael P Greenwood, Mingkwan P Greenwood, Ludimila S Amaral, Mariana R Melo, Debora SA Colombari, Eduardo Colombari, Luis C Reis, Charles CT Hindmarch, Lucila LK Elias, Jose Antunes-Rodrigues, David Murphy, Andre S Mecawi

Journal article  |  2020  |  NEUROENDOCRINOLOGY

BACKGROUND/AIMS: Furosemide is a loop diuretic widely used in clinical practice for the treatment of oedema and hypertension. The ..

A Chemogenetic Tool that Enables Functional Neural Circuit Analysis

Hoai Buu Ngo, Mariana R Melo, Sharon Layfield, Angela A Connelly, Jaspreet K Bassi, Lin Xie, Clement Menuet, Stuart J McDougall, Ross AD Bathgate, Andrew M Allen

Journal article  |  2020  |  CELL REPORTS

Chemogenetics enables manipulation of neuronal activity in experimental animals. While providing information about the transduced ..

PreBotzinger complex neurons drive respiratory modulation of blood pressure and heart rate

Clement Menuet, Angela A Connelly, Jaspreet K Bassi, Mariana R Melo, Sheng Le, Jessica Kamar, Natasha N Kumar, Stuart J McDougall, Simon McMullan, Andrew M Allen

Journal article  |  2020  |  ELIFE

Heart rate and blood pressure oscillate in phase with respiratory activity. A component of these oscillations is generated central..

Renovascular hypertension elevates pulmonary ventilation in rats by carotid body-dependent mechanisms

Mariana Rosso Melo, Silvia Gasparini, Elaine F Silva, Marlusa Karlen-Amarante, Guilherme F Speretta, Mariana R Lauar, Gustavo R Pedrino, Jose Menani, Debora SA Colombari, Daniel B Zoccal, Eduardo Colombari

Journal article  |  2020  |  AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

The two kidney-one clip (2K1C) renovascular hypertension depends on the renin-angiotensin system and sympathetic overactivity. The..

Interaction of central angiotensin II and aldosterone on sodium intake and blood pressure

S Gasparini, MR Melo, PA Nascimento, GMF Andrade-Franze, J Antunes-Rodrigues, GLC Yosten, JV Menani, WK Samson, E Colombari

Journal article  |  2019  |  BRAIN RESEARCH

Recent studies demonstrated an important natriorexigenic mechanism activated by aldosterone acting in the hindbrain. Studies have ..

Importance of the commissural nucleus of the solitary tract in renovascular hypertension

Mariana Rosso Melo, Silvia Gasparini, Guilherme F Speretta, Elaine Fernanda Silva, Gustavo Rodrigues Pedrino, Jose Menani, Daniel B Zoccal, Debora Simoes Almeida Colombari, Eduardo Colombari

Journal article  |  2019  |  HYPERTENSION RESEARCH

The rodent renovascular hypertension model has been used to investigate the mechanisms promoting hypertension. The importance of t..

Importance of All and AT2 receptors in the nucleus of the solitary tract in cardiovascular responses induced by a high-fat diet

Guilherme F Speretta, Prashant J Ruchaya, Maria A Delbin, Mariana R Melo, Hongwei Li, Jose Menani, Colin Sumners, Eduardo Colombari, Mirian Bass, Debora SA Colombari

Journal article  |  2019  |  HYPERTENSION RESEARCH

A high-fat diet (HFD) induces an increase in arterial pressure and a decrease in baroreflex function, which may be associated with..

Involvement of Phox2B Neurons Located in the Commissural NTs with the Maintenance of Hypertension in SH Rats

Mariana Del Rosso de Melo, Sarah JM Ong, Angela A Connelly, Jaspreet K Bassi, Eduardo Colombari, Andrew M Allen

Journal article  |  2019  |  The FASEB Journal