Rhys Brady

The interaction of the circadian and immune system: Desynchrony as a pathological outcome to traumatic brain injury

GR Yamakawa, RD Brady, M Sun, SJ McDonald, SR Shultz, R Mychasiuk

Journal article  |  2020  |  Neurobiology of Sleep and Circadian Rhythms

Behavioral, axonal, and proteomic alterations following repeated mild traumatic brain injury: Novel insights using a clinically relevant rat model.

Louise Pham, David K Wright, William T O'Brien, Jesse Bain, Cheng Huang, Mujun Sun, Pablo M Casillas-Espinosa, Anup D Shah, Ralf B Schittenhelm, Christopher G Sobey, Rhys D Brady, Terence J O'Brien, Richelle Mychasiuk, Sandy R Shultz, Stuart J McDonald

Journal article  |  2020  |  Neurobiology of Disease

A history of mild traumatic brain injury (mTBI) is linked to a number of chronic neurological conditions, however there is still m..

Serum Protein Biomarker Findings Reflective of Oxidative Stress and Vascular Abnormalities in Male, but Not Female, Collision Sport Athletes

Brendan P Major, Stuart J McDonald, William T O'Brien, Georgia F Symons, Meaghan Clough, Daniel Costello, Mujun Sun, Rhys D Brady, Jesse Mccullough, Roxanne Aniceto, I-Hsuan Lin, Meng Law, Richelle Mychasiuk, Terence J O'Brien, Denes V Agoston, Sandy R Shultz

Journal article  |  2020  |  Frontiers in Neurology

The Development of Adolescent Chronic Pain following Traumatic Brain Injury and Surgery: The Role of Diet and Early Life Stress

Sabrina Salberg, Marissa Sgro, Rhys D Brady, Melanie Noel, Richelle Mychasiuk

Journal article  |  2020  |  Developmental Neuroscience

Pain is evolutionarily necessary for survival in that it reduces tissue damage by signaling the body to respond to a harmful stimu..

Experimental traumatic brain injury does not lead to lung infection

Mujun Sun, Rhys D Brady, Brooke Wanrooy, Richelle Mychasiuk, Glenn R Yamakawa, Pablo M Casillas-Espinosa, Connie HY Wong, Sandy R Shultz, Stuart J McDonald

Journal article  |  2020  |  Journal of Neuroimmunology

Traumatic brain injury (TBI) patients often experience post-traumatic infections, especially in the lung. Pulmonary infection is a..

A novel rat model of heterotopic ossification after polytrauma with traumatic brain injury

Rhys D Brady, Michael Z Zhao, Ker R Wong, Pablo M Casilla-Espinosa, Glenn R Yamakawa, Ryan C Wortman, Mujun Sun, Brian L Grills, Richelle Mychasiuk, Terence J O'Brien, Denes Agoston, Peter VS Lee, Stuart J McDonald, Dale L Robinson, Sandy R Shultz

Journal article  |  2020  |  Bone

Neurological heterotopic ossification (NHO) is characterized by abnormal bone growth in soft tissue and joints in response to inju..

Beyond the Brain: Peripheral Interactions after Traumatic Brain Injury

Stuart J McDonald, Jessica M Sharkey, Mujun Sun, Lola M Kaukas, Sandy R Shultz, Renee J Turner, Anna Leonard, Rhys D Brady, Frances Corrigan

Journal article  |  2020  |  Journal of Neurotrauma

Traumatic brain injury (TBI) is a leading cause of death and disability, and there are currently no pharmacological treatments kno..

The need to incorporate aged animals into the preclinical modeling of neurological conditions

Mujun Sun, Stuart J McDonald, Rhys D Brady, Lyndsey Collins-Praino, Glenn R Yamakawa, Mastura Monif, Terence J O'Brien, Geoffrey C Cloud, Christopher G Sobey, Richelle Mychasiuk, David J Loane, Sandy R Shultz

Journal article  |  2020  |  Neuroscience & Biobehavioral Reviews

Neurological conditions such as traumatic brain injury, stroke, Parkinson's disease, epilepsy, multiple sclerosis, and Alzheimer's..

Bone Health in Rats With Temporal Lobe Epilepsy in the Absence of Anti-Epileptic Drugs

Rhys D Brady, Ker Rui Wong, Dale L Robinson, Richelle Mychasiuk, Stuart J McDonald, Ryan A D'Cunha, Glenn R Yamakawa, Mujun Sun, John D Wark, Peter Vee Sin Lee, Terence J O'Brien, Pablo M Casillas-Espinosa, Sandy R Shultz

Journal article  |  2019  |  Frontiers in Pharmacology

Rationale: Epilepsy patients often exhibit reduced bone mineral density and are at an increased risk of bone fracture. Whether the..

Repeated mild traumatic brain injuries induce persistent changes in plasma protein and magnetic resonance imaging biomarkers in the rat

David K Wright, Rhys D Brady, Alaa Kamnaksh, Jack Trezise, Mujun Sun, Stuart J McDonald, Richelle Mychasiuk, Scott C Kolbe, Meng Law, Leigh A Johnston, Terence J O'Brien, Denes V Agoston, Sandy R Shultz

Journal article  |  2019  |  Scientific Reports

A single mild traumatic brain injury (mTBI) typically causes only transient symptoms, but repeated mTBI (RmTBI) is associated with..