Serena Duchi

Formation of alginate microspheres prepared by optimized microfluidics parameters for high encapsulation of bioactive molecules.

Lilith M Caballero Aguilar, Serena Duchi, Carmine Onofrillo, Cathal D O'Connell, Claudia Di Bella, Simon E Moulton

Journal article  |  2021  |  Journal of Colloid and Interface Science

Drug delivery systems such as microspheres have shown potential in releasing biologicals effectively for tissue engineering applic..

FLASH: Fluorescently LAbelled Sensitive Hydrogel to monitor bioscaffolds degradation during neocartilage generation

Carmine Onofrillo, Serena Duchi, Sam Francis, Cathal D O'Connell, Lilith M Caballero Aguilar, Stephanie Doyle, Zhilian Yue, Gordon G Wallace, Peter F Choong, Claudia Di Bella

Journal article  |  2021  |  Biomaterials

Regenerative therapies based on photocrosslinkable hydrogels and stem cells are of growing interest in the field of cartilage repa..

Characterization of Polycaprolactone Nanohydroxyapatite Composites with Tunable Degradability Suitable for Indirect Printing

Stephanie E Doyle, Lauren Henry, Ellen McGennisken, Carmine Onofrillo, Claudia Di Bella, Serena Duchi, Cathal D O'Connell, Elena Pirogova

Journal article  |  2021  |  Polymers

Degradable bone implants are designed to foster the complete regeneration of natural tissue after large-scale loss trauma. Polycap..

Creating In Vitro Three-Dimensional Tumor Models: A Guide for the Biofabrication of a Primary Osteosarcoma Model

Thomas Chow, Ilycia Wutami, Enrico Lucarelli, Peter F Choong, Serena Duchi, Claudia Di Bella

Journal article  |  2020  |  Tissue Engineering Part B: Reviews

Osteosarcoma (OS) is a highly aggressive primary bone tumor. The mainstay for its treatment is multiagent chemotherapy and surgica..

Free-form co-axial bioprinting of a gelatin methacryloyl bio-ink by direct in situ photo-crosslinking during extrusion

CD O'Connell, S Konate, C Onofrillo, R Kapsa, C Baker, S Duchi, T Eekel, Z Yue, S Beirne, G Barnsley, C Di Bella, PF Choong, GG Wallace

Journal article  |  2020  |  Bioprinting

Trends in Bone Metastasis Modeling

Roberta Laranga, Serena Duchi, Toni Ibrahim, Ania Naila Guerrieri, Davide Maria Donati, Enrico Lucarelli

Journal article  |  2020  |  Cancers

Bone is one of the most common sites for cancer metastasis. Bone tissue is composed by different kinds of cells that coexist in a ..

Mesenchymal stromal cells mediated delivery of photoactive nanoparticles inhibits osteosarcoma growth in vitro and in a murine in vivo ectopic model.

Stefania Lenna, Chiara Bellotti, Serena Duchi, Elisa Martella, Marta Columbaro, Barbara Dozza, Marco Ballestri, Andrea Guerrini, Giovanna Sotgiu, Tommaso Frisoni, Luca Cevolani, Greta Varchi, Mauro Ferrari, Davide Maria Donati, Enrico Lucarelli

Journal article  |  2020  |  Journal of Experimental and Clinical Cancer Research

BACKGROUND: Osteosarcoma (OS) is an aggressive malignant neoplasm that still suffers from poor prognosis in the case of distal met..

Bioprinting Stem Cells in Hydrogel for In Situ Surgical Application: A Case for Articular Cartilage.

Serena Duchi, Carmine Onofrillo, Cathal O'Connell, Gordon G Wallace, Peter Choong, Claudia Di Bella

Journal article  |  2020  |  Methods in molecular biology (Clifton, N.J.)

Three-dimensional (3D) bioprinting is driving major innovations in the area of cartilage tissue engineering. As an alternative to ..

Characterizing Bioinks for Extrusion Bioprinting: Printability and Rheology.

Cathal O'Connell, Junxiang Ren, Leon Pope, Yifan Li, Anushree Mohandas, Romane Blanchard, Serena Duchi, Carmine Onofrillo

Journal article  |  2020  |  Methods in molecular biology (Clifton, N.J.)

In recent years, new technologies based on 3D bioprinting have emerged as ideal tools with which to arrange cells and biomaterials..

Concise review: Human articular cartilage repair: Sources and detection of cytotoxicity and genotoxicity in photo-crosslinkable hydrogel bioscaffolds

Cheryl Lee, Cathal D O'Connell, Carmine Onofrillo, Peter FM Choong, Claudia Di Bella, Serena Duchi

Journal article  |  2019  |  STEM CELLS TRANSLATIONAL MEDICINE

Three-dimensional biofabrication using photo-crosslinkable hydrogel bioscaffolds has the potential to revolutionize the need for t..