Serena Duchi

3D printed multiphasic scaffolds for osteochondral repair: Challenges and opportunities

SE Doyle, F Snow, S Duchi, CD O’connell, C Onofrillo, C Di Bella, E Pirogova

Journal article  |  2021  |  International Journal of Molecular Sciences

Osteochondral (OC) defects are debilitating joint injuries characterized by the loss of full thickness articular cartilage along w..

Enhanced Electroactivity, Mechanical Properties, and Printability through the Addition of Graphene Oxide to Photo-Cross-linkable Gelatin Methacryloyl Hydrogel

Alexandre Xavier Mendes, Saimon Moraes Silva, Cathal D O'Connell, Serena Duchi, Anita F Quigley, Robert M Kapsa, Simon E Moulton

Journal article  |  2021  |  ACS BIOMATERIALS SCIENCE & ENGINEERING

The human tissues most sensitive to electrical activity such as neural and muscle tissues are relatively soft, and yet traditional..

Printing between the Lines: Intricate Biomaterial Structures Fabricated via Negative Embodied Sacrificial Template 3D (NEST3D) Printing

Stephanie E Doyle, Serena Duchi, Carmine Onofrillo, Anita Quigley, Claudia Di Bella, Elena Pirogova, Cathal D O'Connell

Journal article  |  2021  |  ADVANCED MATERIALS TECHNOLOGIES

Extrusion printing techniques are widely used across tissue engineering and related fields for producing 3D structures from biocom..

Formation of alginate microspheres prepared by optimized microfluidics parameters for high encapsulation of bioactive molecules

Lilith M Caballero Aguilar, Serena Duchi, Carmine Onofrillo, Cathal D O'Connell, Claudia Di Bella, Simon E Moulton

Journal article  |  2021  |  JOURNAL OF COLLOID AND INTERFACE SCIENCE

Drug delivery systems such as microspheres have shown potential in releasing biologicals effectively for tissue engineering applic..

FLASH: Fluorescently LAbelled Sensitive Hydrogel to monitor bioscaffolds degradation during neocartilage generation

Carmine Onofrillo, Serena Duchi, Sam Francis, Cathal D O'Connell, Lilith M Caballero Aguilar, Stephanie Doyle, Zhilian Yue, Gordon G Wallace, Peter F Choong, Claudia Di Bella

Journal article  |  2021  |  BIOMATERIALS

Regenerative therapies based on photocrosslinkable hydrogels and stem cells are of growing interest in the field of cartilage repa..

Characterization of Polycaprolactone Nanohydroxyapatite Composites with Tunable Degradability Suitable for Indirect Printing

Stephanie E Doyle, Lauren Henry, Ellen McGennisken, Carmine Onofrillo, Claudia Di Bella, Serena Duchi, Cathal D O'Connell, Elena Pirogova

Journal article  |  2021  |  POLYMERS

Degradable bone implants are designed to foster the complete regeneration of natural tissue after large-scale loss trauma. Polycap..

Microencapsulation of growth factors by microfluidic system

Lilith M Caballero-Aguilar, Serena Duchi, Anita Quigley, Carmine Onofrillo, Claudia Di Bella, Simon E Moulton

Journal article  |  2021  |  METHODSX

The encapsulation of growth factors is an important component of tissue engineer- ing. Using microspheres is a convenient approach..

Creating In Vitro Three-Dimensional Tumor Models: A Guide for the Biofabrication of a Primary Osteosarcoma Model

Thomas Chow, Ilycia Wutami, Enrico Lucarelli, Peter F Choong, Serena Duchi, Claudia Di Bella

Journal article  |  2020  |  TISSUE ENGINEERING PART B-REVIEWS

Osteosarcoma (OS) is a highly aggressive primary bone tumor. The mainstay for its treatment is multiagent chemotherapy and surgica..

Free-form co-axial bioprinting of a gelatin methacryloyl bio-ink by direct in situ photo-crosslinking during extrusion

CD O'Connell, S Konate, C Onofrillo, R Kapsa, C Baker, S Duchi, T Eekel, Z Yue, S Beirne, G Barnsley, C Di Bella, PF Choong, GG Wallace

Journal article  |  2020  |  Bioprinting

3D bioprinting is an emerging technology for arranging cells and biomaterials in 3D, with the goal to develop functional substitut..

Trends in Bone Metastasis Modeling

Roberta Laranga, Serena Duchi, Toni Ibrahim, Ania Naila Guerrieri, Davide Maria Donati, Enrico Lucarelli

Journal article  |  2020  |  CANCERS

Bone is one of the most common sites for cancer metastasis. Bone tissue is composed by different kinds of cells that coexist in a ..