Dr. Serena Duchi is a cellular biologist with special interest in osteochondral tissue engineering.
Dr Duchi graduated in Biology in 2004 (University of Bologna, Italy) and subsequently obtained her qualification as a professional Biologist in 2005 (University of Bologna, Italy).
She obtained a Master degree in Bioinformatics in 2005 with a thesis in comparative genomics, thorugh an internship program between University of Bologna-Italy and Centro de Investigación Príncipe Felipe (CIPF) Valencia – Spain. She then obtained her PhD in Cell, Molecular and Industrial Biology in 2009 through an international program between University of Bologna-Italy and Medical University of South Carolina (MUSC), Hollings Cancer Center, Charleston, SC-USA, with a thesis in tumor cell biology and endocytosis mechanisms in in vitro and in vivo models. She was awarded a post-doctoral fellowship at the IFOM-FIRC Institute of Molecular Oncology, Milan-Italy in 2009, where she acquired a strong background in the regulation of tumor suppression and endocytosis aimed to design new molecular target chemotherapeutic drugs. She then specialized in the treatment of musculoskeletal tumors at the Rizzoli Orthopaedics Institute, Bologna-Italy, where she led as senior investigator different projects:
• identification of the differentiation capabilities, onset of senescence and tumorigenicity signal transduction in mesenchymal stem/stromal cells (MSC) isolated and expanded from osteosarcoma affected patients and from healthy subjects;
• use of MSC for the transport of chemotherapeutic drugs as innovative therapeutic approach for the treatment of osteosarcoma;
• use of MSC in scaffold based regenerative medicine for osteo-chondral defect and diseases treatments.
Dr. Duchi moved to Melbourne in April 2016 as an academic research fellow and she’s currently working at the St Vincent's Hospital, 3DBioFab facility @ ACMD. Dr Duchi is the cellular biologist member of the Cartilage Regeneration Program at the Department of Surgery-Melbourne University, branch of the large Advanced Limb Regeneration (ALR) Program, directed by Prof Peter Choong.
She is a senior biologist involved in the in vitro and in vivo studies in the laboratory for the execution of the "Next generation of Bioprinting for cartilage regeneration" project. She's also involved in article and grants writing, PhD and student supervision, and research official presentations.
The Cartilage regeneration program is centred on the use of advanced 3D printing technologies, including surgical 3D printing and stem cells, for the regeneration of healthy articular cartilage both in vitro and in vivo.
She is specialized in
• human stem cells isolation, characterizations and differentiation in osteochondral lineage;
• 3D bioprinting and cultivation of samples for cartilage tissue regeneration;
• imaging techniques for epifluorescence, confocal and time-lapse microscopy, FRET, TIRF, Light-Sheet Microscopy.
Find out more about Serena Duchi's experience
Serena Duchi's highlights
FEATURED Journal article
Protocols for Culturing and Imaging a Human Ex Vivo Osteochondral Model for Cartilage Biomanufacturing Applications
Read moreSerena Duchi's selected work
Scholarly Works
Displaying the 43 most recent scholarly works by Serena Duchi.
Keyword Analysis
Honours, Awards and Fellowships
Minor Infrastructure Funding Scheme 2017 (Melbourne Medical School), 12k AUD
Research Endowment Fund, St.Vincent Hospital-Melbourne, 20k AUD
My First AIRC Grant 2015, 176k €, AIRC Italian Association for Cancer Research (Italy),
AIRC/FIRC fellowship, 60k €
Credentials
Positions
Research Fellow
Surgery - St Vincent'S Hospital
National Research Council, Institute Of Organic Synthesis And Photoreactivity, Bologna-Italy
ISOF-CNR
Australasian Society For Biomaterials And Tissue Engineering, Https://Www.Asbte.Org/
ASBTE
Centre Of Excellence For Electromaterials Science, Intelligent Polymer Research Institute, Innovation Campus, University Of Wollongong
ARC
Italian Digital Biomanufacturing Network, Http://Idbn.Org
IDBN
Italian Group Mesenchymal Stem Cells, Http://Www.Gismonline.It/Index.Php
GISM
Education
PhD
University of Bologna
Bioinformatics
University of Bologna
Qualification as a Professional Biologist
University of Bologna
Biology
University of Bologna