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Understanding The Dynamic Regulation Of Exhausted And Tissue-Resident Memory T Cells Diffe..
IRF4 Activity Is Required in Established Plasma Cells to Regulate Gene Transcription and M..
Transcription Factor IRF4 Promotes CD8( ) T Cell Exhaustion and Limits the Development of ..
Bone marrow transplantation improves proximal tubule dysfunction in a mouse model of Dent ..
Displaying the most recent project by Sarah Gabriel.
Displaying the 10 most recent scholarly works by Sarah Gabriel.
MCL-1 is essential for survival but dispensable for metabolic fitness of FOXP3( )regulatory T cells
Charis E Teh, Alissa K Robbins, Darren C Henstridge, Grant Dewson, Sarah T Diepstraten, Gemma Kelly, Mark A Febbraio, Sarah S Gabriel, Lorraine A O'Reilly, Andreas Strasser, Daniel HD Gray
Journal article | 2020 | Cell Death & Differentiation
FOXP3+ regulatory T (Treg) cells are essential for maintaining immunological tolerance. Given their importance in immune-related d..
IRF4 Activity Is Required in Established Plasma Cells to Regulate Gene Transcription and Mitochondrial Homeostasis
Michael Sze Yuan Low, Erica J Brodie, Pasquale L Fedele, Yang Liao, George Grigoriadis, Andreas Strasser, Axel Kallies, Simon N Willis, Julie Tellier, Wei Shi, Sarah Gabriel, Kristy O'Donnell, Catherine Pitt, Stephen L Nutt, David Tarlinton
Journal article | 2019 | Cell Reports
The transcription factor interferon regulatory factor 4 (IRF4) is critical for the development, maintenance, and function of plasm..
Transcription Factor IRF4 Promotes CD8( ) T Cell Exhaustion and Limits the Development of Memory-like T Cells during Chronic Infection
Kevin Man, Sarah S Gabriel, Yang Liao, Renee Gloury, Simon Preston, Darren C Henstridge, Marc Pellegrini, Dietmar Zehn, Friederike Berberich-Siebelt, Mark A Febbraio, Wei Shi, Axel Kallies
Journal article | 2017 | Immunity
Bone marrow transplantation improves proximal tubule dysfunction in a mouse model of Dent disease.
Sarah S Gabriel, Hendrica Belge, Alkaly Gassama, Huguette Debaix, Alessandro Luciani, Thomas Fehr, Olivier Devuyst
Journal article | 2017 | Kidney International
Dent disease is a rare X-linked tubulopathy caused by mutations in the endosomal chloride-proton exchanger (ClC-5) resulting in de..
Bcl-2 inhibition to overcome memory cell barriers in transplantation.
PE Cippà, SS Gabriel, AK Kraus, J Chen, T Wekerle, A Guimezanes, RP Wüthrich, T Fehr
Journal article | 2014 | American Journal of Transplantation
Memory T cells (Tm) represent a major barrier for immunosuppression and tolerance induction after solid organ transplantation. Tak..
Targeting apoptosis to induce stable mixed hematopoietic chimerism and long-term allograft survival without myelosuppressive conditioning in mice.
Pietro E Cippà, Sarah S Gabriel, Jin Chen, Philip D Bardwell, Andrew Bushell, Annick Guimezanes, Anna K Kraus, Thomas Wekerle, Rudolf P Wüthrich, Thomas Fehr
Journal article | 2013 | Blood
Induction of mixed hematopoietic chimerism results in donor-specific immunological tolerance by apoptosis-mediated deletion of don..
Microbiology And Immunology