Jenny McKimm-Breschkin

Substitutions at H134 and in the 430-loop region in influenza B neuraminidases can confer reduced susceptibility to multiple neuraminidase inhibitors

Peter G Mohr, Janelle Williams, Masato Tashiro, Victor A Streltsov, Jennifer L McKimm-Breschkin

Journal article  |  2020  |  Antiviral Research

With the introduction of the influenza specific neuraminidase inhibitors (NAIs) in 1999, there were concerns about the emergence a..

A clinical trial lacking a control group.

Mike Bray, Jennifer McKimm-Breschkin

Journal article  |  2019  |  International Journal of Infectious Diseases

Passaging of an influenza A(H1N1)pdm09 virus in a difluoro sialic acid inhibitor selects for a novel, but unfit I106M neuraminidase mutant

Jennifer L McKimm-Breschkin, Susan Barrett, Charley McKenzie-Kludas, Julie McAuley, Victor A Streltsov, Stephen G Withers

Journal article  |  2019  |  Antiviral Research

An influenza A(H1N1)pdm09 and an influenza B virus were passaged in 3-fluoro(eq)-4-guanidino difluoro sialic acid (3Feq4Gu DFSA), ..

Structure of an Influenza A virus N9 neuraminidase with a tetrabrachion-domain stalk

Victor A Streltsov, Peter M Schmidt, Jennifer L McKimm-Breschkin

Journal article  |  2019  |  Acta Crystallographica Section F Structural Biology Communications

Influenza Virus Neuraminidase Structure and Functions

Julie L McAuley, Brad P Gilbertson, Sanja Trifkovic, Lorena E Brown, Jennifer L McKimm-Breschkin

Journal article  |  2019  |  Frontiers in Microbiology

Identification of Indonesian Glade 2.1 highly pathogenic influenza A(H5N1) viruses with N294S and S246N neuraminidase substitutions which further reduce oseltamivir susceptibility

Jennifer L McKimm-Breschkin, Susan Barrett, Frank YK Wong, undefined Pudjiatmoko, Muhammad Azhar, Paul Selleck, Kelly R Davies, Nining Hartaningsih, James McGrane

Journal article  |  2018  |  Antiviral Research

Structural and Functional Analysis of Anti-Influenza Activity of 4-, 7-, 8-and 9-Deoxygenated 2,3-Difluoro-N-acetylneuraminic Acid Derivatives

Jennifer L McKimm-Breschkin, Susan Barrett, Patricia A Pilling, Stefan Hader, Andrew G Watts, Victor A Streltsov

Journal article  |  2018  |  Journal of Medicinal Chemistry

Mouse Saliva Inhibits Transit of Influenza Virus to the Lower Respiratory Tract by Efficiently Blocking Influenza Virus Neuraminidase Activity

Brad Gilbertson, Wy Ching Ng, Simon Crawford, Jenny L McKimm-Breschkin, Lorena E Brown

Journal article  |  2017  |  Journal of Virology