Simon Monard

Transcriptome sequencing and multi-plex imaging of prostate cancer microenvironment reveals a dominant role for monocytic cells in progression

Stefano Mangiola, Patrick McCoy, Martin Modrak, Fernando Souza-Fonseca-Guimaraes, Daniel Blashki, Ryan Stuchbery, Simon P Keam, Michael Kerger, Ken Chow, Chayanica Nasa, Melanie Le Page, Natalie Lister, Simon Monard, Justin Peters, Phil Dundee, Scott G Williams, Anthony J Costello, Paul J Neeson, Bhupinder Pal, Nicholas D Huntington, et al.

Journal article  |  2021  |  BMC CANCER

BACKGROUND: Prostate cancer is caused by genomic aberrations in normal epithelial cells, however clinical translation of findings ..

Procedures for Flow Cytometry-Based Sorting of Unfixed Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infected Cells and Other Infectious Agents

Kristen M Reifel, Brandon K Swan, Evan R Jellison, David Ambrozak, Jan Baijer, Richard Nguyen, Simon Monard, Geoffrey Lyon, Benjamin Fontes, Stephen P Perfetto

Journal article  |  2020  |  CYTOMETRY PART A

In response to the recent COVID-19 pandemic, many laboratories are involved in research supporting SARS-CoV-2 vaccine development ..

Novel Impactor and Microsphere-Based Assay Used to Measure Containment of Aerosols Generated in a Flow Cytometer Cell Sorter

Stephen P Perfetto, Phillip J Hogarth, Simon Monard, Ben Fontes, Kristen M Reifel, Brandon K Swan, Jan Baijer, Evan R Jellison, Geoffrey Lyon, Patty Lovelace, Richard Nguyen, David Ambrozak, Kevin L Holmes

Journal article  |  2019  |  CYTOMETRY PART A

Today's state-of-the-art cell sorting flow cytometers are equipped with aerosol containment systems designed to evacuate aerosols ..

Inhibition of Hematopoietic Cell Kinase Activity Suppresses Myeloid Cell-Mediated Colon Cancer Progression

Ashleigh R Poh, Christopher G Love, Frederick Masson, Adele Preaudet, Cary Tsui, Lachlan Whitehead, Simon Monard, Yelena Khakham, Lotta Burstroem, Guillaume Lessene, Oliver Sieber, Clifford Lowell, Tracy L Putoczki, Robert JJ O'Donoghue, Matthias Ernst

Journal article  |  2017  |  CANCER CELL

Aberrant activation of the SRC family kinase hematopoietic cell kinase (HCK) triggers hematological malignancies as a tumor cell-i..

Chromosome sorting for the masses?

Simon Monard

Journal article  |  2016  |  CYTOMETRY PART A

A rapid method to verify single-cell deposition setup for cell sorters

Olivia Roos Rodrigues, Simon Monard

Journal article  |  2016  |  CYTOMETRY PART A

Studying single cells reveals biology that cannot be explored using bulk techniques. Cell sorters provide the opportunity of separ..

International Society for the Advancement of Cytometry Cell Sorter Biosafety Standards

Kevin L Holmes, Benjamin Fontes, Philip Hogarth, Richard Konz, Simon Monard, Charles H Pletcher, Robert B Wadley, Ingrid Schmid, Stephen P Perfetto

Journal article  |  2014  |  CYTOMETRY PART A

Flow cytometric cell sorting of biological specimens has become prevalent in basic and clinical research laboratories. These speci..

Long-term maintenance of virus-specific effector memory CD8 T cells in the lung airways depends on proliferation.

Robert J Hogan, Linda S Cauley, Kenneth H Ely, Tres Cookenham, Alan D Roberts, Jean W Brennan, Simon Monard, David L Woodland

Journal article  |  2002  |  J Immunol

Recent studies have shown that virus-specific effector memory T cells can be recovered from the lung airways long after clearance ..

Cyclic ADP-ribose production by CD38 regulates intracellular calcium release, extracellular calcium influx and chemotaxis in neutrophils and is required for bacterial clearance in vivo.

S Partida-Sánchez, DA Cockayne, S Monard, EL Jacobson, N Oppenheimer, B Garvy, K Kusser, S Goodrich, M Howard, A Harmsen, TD Randall, FE Lund

Journal article  |  2001  |  Nat Med

Cyclic ADP-ribose is believed to be an important calcium-mobilizing second messenger in invertebrate, mammalian and plant cells. C..

Virologic and immunologic effect of antiretroviral therapy on HIV-1 in gut-associated lymphoid tissue.

AH Talal, S Monard, M Vesanen, Z Zheng, A Hurley, Y Cao, F Fang, L Smiley, J Johnson, R Kost, MH Markowitz

Journal article  |  2001  |  J Acquir Immune Defic Syndr

OBJECTIVES: We evaluated virologic and immunologic responses to antiretroviral therapy in gut-associated lymphoid tissue (GALT) co..