Emma Link

Quality of life after breast-conserving therapy and adjuvant radiotherapy for non-low-risk ductal carcinoma in situ (BIG 3-07/TROG 07.01): 2-year results of a randomised, controlled, phase 3 trial

Madeleine T King, Emma K Link, Tim J Whelan, Ivo A Olivotto, Ian Kunkler, Antonia Helen Westenberg, Guenther Gruber, Penny Schofield, Boon H Chua

Journal article  |  2020  |  The Lancet Oncology

BACKGROUND: BIG 3-07/TROG 07.01 is an international, multicentre, randomised, controlled, phase 3 trial evaluating tumour bed boos..

Prostate-specific membrane antigen PET-CT in patients with high-risk prostate cancer before curative-intent surgery or radiotherapy (proPSMA): a prospective, randomised, multicentre study

Michael S Hofman, Nathan Lawrentschuk, Roslyn J Francis, Colin Tang, Ian Vela, Paul Thomas, Natalie Rutherford, Jarad M Martin, Mark Frydenberg, Ramdave Shakher, Lih-Ming Wong, Kim Taubman, Sze Ting Lee, Edward Hsiao, Paul Roach, Michelle Nottage, Ian Kirkwood, Dickon Hayne, Emma Link, Petra Marusic, et al.

Journal article  |  2020  |  The Lancet

BACKGROUND: Conventional imaging using CT and bone scan has insufficient sensitivity when staging men with high-risk localised pro..

Pembrolizumab with chemoradiotherapy as treatment for muscle invasive bladder cancer: A planned interim analysis of safety and efficacy of the PCR-MIB phase II clinical trial (ANZUP 1502)

Andrew James Weickhardt, Farshad Foroudi, Nathan Lawrentschuk, Laura Galleta, Amanda Seegum, Alan Herschtal, Emma Link, Margaret Mary McJannett, Elizabeth Chien Hern Liow, Peter S Grimison, Alison Yan Zhang, Nitya Patanjali, Siobhan Ng, Robert Goodwin, Colin Tang, Colin Chen, Elizabeth J Hovey, George Hruby, Alexander David Guminski, Ian D Davis

Conference Proceedings  |  2020  |  JOURNAL OF CLINICAL ONCOLOGY

The INTERNET STUDY: A phase II study of everolimus in patients with fluorodeoxyglucose (F-18) positron-emission tomography positive intermediate grade pancreatic neuroendocrine tumors

Mei Sim Lung, Rodney J Hicks, Nick Pavlakis, Emma Link, Michael Jefford, Benjamin Thomson, David K Wyld, Winston Liauw, Timothy Akhurst, Narmatha Kuru, Michael Michael

Journal article  |  2020  |  Asia-Pacific Journal of Clinical Oncology

AIMS: This multicenter phase II trial evaluates the efficacy of everolimus in poor prognosis grade 2 (G2) pancreatic neuroendocrin..

International comparison of cosmetic outcomes of breast conserving surgery and radiation therapy for women with ductal carcinoma in situ of the breast

Ivo A Olivotto, Emma Link, Claire Phillips, Timothy J Whelan, Guy Bryant, Ian H Kunkler, A Helen Westenberg, Kash Purohit, Verity Ahern, Peter H Graham, Mohamed Akra, Orla McArdle, Joanna J Ludbrook, Jennifer A Harvey, John H Maduro, Carine Kirkove, Guenther Gruber, Joseph D Martin, Ian D Campbell, Geoff P Delaney, et al.

Journal article  |  2020  |  Radiotherapy and Oncology

PURPOSE: To assess the cosmetic impact of breast conserving surgery (BCS), whole breast irradiation (WBI) fractionation and tumour..

First-in-human phase I clinical trial of a combined immune modulatory approach using TetMYB vaccine and Anti-PD-1 antibody in patients with advanced solid cancer including colorectal or adenoid cystic carcinoma: The MYPHISMO study protocol (NCT03287427)

Toan Pham, Lloyd Pereira, Sara Roth, Laura Galletta, Emma Link, Tim Akhurst, Ben Solomon, Michael Michael, Phillip Darcy, Shienny Sampurno, Alexander Heriot, Robert Ramsay, Jayesh Desai

Journal article  |  2019  |  Contemporary Clinical Trials Communications

Background: MYB is a transcription factor that is overexpressed in colorectal cancer (CRC) and also a driver mutation in adenoid c..

First-in-Human RNA Polymerase I Transcription Inhibitor CX-5461 in Patients with Advanced Hematologic Cancers: Results of a Phase I Dose-Escalation Study

Amit Khot, Natalie Brajanovski, Donald P Cameron, Nadine Hein, Kylee H Maclachlan, Elaine Sanij, John Lim, John Soong, Emma Link, Piers Blombery, Ella R Thompson, Andrew Fellowes, Karen E Sheppard, Grant A McArthur, Richard B Pearson, Ross D Hannan, Gretchen Poortinga, Simon J Harrison

Journal article  |  2019  |  Cancer Discovery

RNA polymerase I (Pol I) transcription of ribosomal RNA genes (rDNA) is tightly regulated downstream of oncogenic pathways, and it..

Utility of routine oral contrast study for detecting postesophagectomy anastomotic leak - a systematic review and meta-analysis

G Yonis, CS Cabalag, E Link, CP Duong

Journal article  |  2019  |  Diseases of the Esophagus

Oral contrast studies are used to detect anastomotic leak (AL) postesophagectomy. However, recent evidence suggests oral contrast ..

Phase II trial PD-L1/PD-1 blockade avelumab with chemoradiotherapy for locally advanced resectable T3B-4/N1-2 rectal cancer: The Ave-Rec trial.

Michael Michael, Rachel Wong, Sanjeev Singh Gill, David Goldstein, Sam Ngan, Alexander Graham Heriot, Emma Link, Maria Farrell, Paul J Neeson, Robert George Ramsay, Kasmira Wilson, Catherine Mitchell, Jeanne Tie, Nick Pavlakis, John Raymond Zalcberg, Eva Segelov

Conference Proceedings  |  2019  |  Journal of Clinical Oncology

Feasibility of 5-fluorouracil pharmacokinetic monitoring using the My-5FU PCM (TM) system in a quaternary oncology centre

Michael Moloney, David Faulkner, Emma Link, Danny Rischin, Ben Solomon, Annette M Lim, John R Zalcberg, Michael Jefford, Michael Michael

Journal article  |  2018  |  Cancer Chemotherapy and Pharmacology

The utility of genomics and functional imaging to predict Sunitinib PK and PD: The Predict SU study.

Michael Michael, David William Pook, Vinod Ganju, Emma Link, Guy C Toner, Rodney J Hicks, Anetta Matera, Mick Thompson, Carleen Cullinane, Ian Campbell, Matthew Burge, Christos Stelios Karapetis

Conference Proceedings  |  2018  |  Journal of Clinical Oncology

Idarubicin Dose Escalation During Consolidation Therapy for Adult Acute Myeloid Leukemia

Kenneth F Bradstock, Emma Link, Juliana Di Iulio, Jeff Szer, Paula Marlton, Andrew H Wei, Arno Enno, Anthony Schwarer, Ian D Lewis, James D'Rozario, Luke Coyle, Gavin Cull, Phillip Campbell, Michael F Leahy, Uwe Hahn, Paul Cannell, Campbell Tiley, Ray M Lowenthal, John Moore, Kimberly Cartwright, et al.

Journal article  |  2017  |  Journal of Clinical Oncology

The utility of genomics and functional imaging to predict irinotecan pharmacokinetics and pharmacodynannics: The PREDICT IR study.

Michael Michael, Winston Liauw, Sue-Anne McLachlan, Emma Link, Anetta Matera, Mick Thompson, Michael Jefford, Rodney J Hicks, Carleen Cullinane, Ian Campbell, Philip James Beale, Christos Stelios Karapetis, Timothy Price, Matthew E Burge

Conference Proceedings  |  2017  |  Journal of Clinical Oncology

Upfront lower dose lenalidomide is less toxic and does not compromise efficacy for vulnerable patients with relapsed refractory multiple myeloma: final analysis of the phase II RevLite study

Hang Quach, Liam Fernyhough, Ross Henderson, Gillian Corbett, Bart Baker, Peter Browett, Hilary Blacklock, Cecily Forsyth, Craig Underhill, Paul Cannell, Judith Trotman, Annette Neylon, Simon Harrison, Emma Link, Arlene Swern, Linda Cowan, Meletios A Dimopoulos, H Miles Prince

Journal article  |  2017  |  British Journal of Haematology

Results of a phase II study of thalidomide and azacitidine in patients with clinically advanced myelodysplastic syndromes (MDS), chronic myelomonocytic leukemia (CMML) and low blast count acute myeloid leukemia (AML)

Melita Kenealy, Nigel Patton, Robin Filshie, Andrew Nicol, Shir-Jing Ho, Mark Hertzberg, Tony Mills, Ian Prosser, Emma Link, Linda Cowan, Diana Zannino, John F Seymour

Journal article  |  2017  |  Leukemia & Lymphoma

Prevalence and Intensity of Pain and Other Physical and Psychological Symptoms in Adolescents and Young Adults Diagnosed with Cancer on Referral to a Palliative Care Service

Rachel E Hughes, Lucy R Holland, Diana Zanino, Emma Link, Natasha Michael, Kate E Thompson

Journal article  |  2015  |  Journal of Adolescent and Young Adult Oncology

The addition of dexamethasone to bortezomib for patients with relapsed multiple myeloma improves outcome but ongoing maintenance therapy has minimal benefit

Simon J Harrison, Hang Quach, Emma Link, Huaibao Feng, Joanne Dean, Michael Copeman, Helgi Van de Velde, Anthony Schwarer, Bartrum Baker, Andrew Spencer, John Catalano, Philip Campbell, Bradley Augustson, Ken Romeril, Henry Miles Prince

Journal article  |  2015  |  American Journal of Hematology

Improving Patient Selection for F-18-FDG PET Scanning in the Staging of Gastric Cancer

Yui Kaneko, William K Murray, Emma Link, Rodney J Hicks, Cuong Duong

Journal article  |  2015  |  Journal of Nuclear Medicine

Laparoscopy and peritoneal cytology: important prognostic tools to guide treatment selection in gastric adenocarcinoma

Saam S Tourani, Carlos Cabalag, Emma Link, Steven TF Chan, Cuong P Duong

Journal article  |  2015  |  ANZ Journal of Surgery

A randomized trial of prophylactic palifermin on gastrointestinal toxicity after intensive induction therapy for acute myeloid leukaemia

Kenneth F Bradstock, Emma Link, Marnie Collins, Juliana Di Iulio, Ian D Lewis, Anthony Schwarer, Arno Enno, Paula Marlton, Uwe Hahn, Jeff Szer, Gavin Cull, John F Seymour

Journal article  |  2014  |  British Journal of Haematology

Aggressive Behavior of Cutaneous Squamous Cell Carcinoma in Patients With Chronic Lymphocytic Leukemia

Jonathan M Tomaszewski, Haim Gavriel, Emma Link, Sholeh Boodhun, Andrew Sizeland, June Corry

Journal article  |  2014  |  The Laryngoscope

Plerixafor plus pegfilgrastim is a safe, effective mobilization regimen for poor or adequate mobilizers of hematopoietic stem and progenitor cells: a phase I clinical trial

KE Herbert, L Demosthenous, G Wiesner, E Link, DA Westerman, N Came, DS Ritchie, S Harrison, JF Seymour, HM Prince

Journal article  |  2014  |  Bone Marrow Transplantation

Impact of advancing age on treatment and outcomes in anal cancer

Marcus Foo, Emma Link, Trevor Leong, Julie Chu, Mark T Lee, Sarat Chander, Phillip K Tran, Jonathan M Tomaszewski, Michael Michael, Alexander Heriot, Samuel Y Ngan

Journal article  |  2014  |  Acta Oncologica

Perioperative epidural analgesia reduces cancer recurrence after gastro-oesophageal surgery

JG Hiller, MB Hacking, EK Link, KL Wessels, BJ Riedel

Journal article  |  2014  |  Acta Anaesthesiologica Scandinavica

Can We Predict Plan Quality for External Beam Partial Breast Irradiation: Results of a Multicenter Feasibility Study (Trans Tasman Radiation Oncology Group Study 06.02)

Tomas Kron, David Willis, Emma Link, Margot Lehman, Gillian Campbell, Peter O'Brien, Boon Chua

Journal article  |  2013  |  International Journal of Radiation: Oncology - Biology - Physics

Pegfilgrastim compared with filgrastim for cytokine-alone mobilization of autologous haematopoietic stem and progenitor cells

KE Herbert, P Gambell, EK Link, A Mouminoglu, DM Wall, SJ Harrison, DS Ritchie, JF Seymour, HM Prince

Journal article  |  2013  |  Bone Marrow Transplantation

Cosmetic Outcome and Seroma Formation After Breast-Conserving Surgery With Intraoperative Radiation Therapy Boost for Early Breast Cancer

Sashendra Senthi, Emma Link, Boon H Chua

Journal article  |  2012  |  International Journal of Radiation: Oncology - Biology - Physics

Effect of PET/CT on Management of Patients with Non-Small Cell Lung Cancer: Results of a Prospective Study with 5-Year Survival Data

Deborah L Gregory, Rodney J Hicks, Annette Hogg, David S Binns, Poh Lin Shum, Alvin Milner, Emma Link, David L Ball, Michael P Mac Manus

Journal article  |  2012  |  Journal of Nuclear Medicine

Twenty-Five-Year Experience With Radical Chemoradiation for Anal Cancer

Jonathan M Tomaszewski, Emma Link, Trevor Leong, Alexander Heriot, Melisa Vazquez, Sarat Chander, Julie Chu, Marcus Foo, Mark T Lee, Craig A Lynch, John Mackay, Michael Michael, Phillip Tran, Samuel Y Ngan

Journal article  |  2012  |  International Journal of Radiation: Oncology - Biology - Physics

Correlations between histopathological diagnosis of chemotherapy-induced hepatic injury, clinical features, and perioperative morbidity

Charles HC Pilgrim, Laveniya Satgunaseelan, Alan Pham, William Murray, Emma Link, Marty Smith, Val Usatoff, Peter M Evans, Simon Banting, Benjamin N Thomson, Wayne A Phillips, Michael Michael

Journal article  |  2012  |  HPB: the official journal of the IHPBA

A high rate of durable responses with romidepsin, bortezomib, and dexamethasone in relapsed or refractory multiple myeloma

Simon J Harrison, Hang Quach, Emma Link, John F Seymour, David S Ritchie, Sam Ruell, Joanne Dean, Henry Januszewicz, Ricky Johnstone, Paul Neeson, Michael Dickinson, Jean Nichols, H Miles Prince

Journal article  |  2011  |  Blood

FDG-PET metabolic response predicts outcomes in anal cancer managed with chemoradiotherapy

FL Day, E Link, S Ngan, T Leong, K Moodie, C Lynch, M Michael, E de Winton, A Hogg, RJ Hicks, A Heriot

Journal article  |  2011  |  British Journal of Cancer

Metabolic Response of Rectal Cancer Assessed by 18-FDG PET Following Chemoradiotherapy is Prognostic for Patient Outcome

JMC Yeung, V Kalff, RJ Hicks, E Drummond, E Link, Y Taouk, M Michael, S Ngan, AC Lynch, AG Heriot

Journal article  |  2011  |  Diseases of the Colon and Rectum

Current hepatitis B screening practices and clinical experience of reactivation in patients undergoing chemotherapy for solid tumors: a nationwide survey of medical oncologists.

Fiona L Day, Emma Link, Karin Thursky, Danny Rischin

Journal article  |  2011  |  Journal of Oncology Practice

PURPOSE: Universal screening for chronic hepatitis B virus (HBV) before chemotherapy has been recommended by the Centers for Disea..