Charbel Darido

Inactivation of Zeb1 in GRHL2-deficient mouse embryos rescues mid-gestation viability and secondary palate closure

Marina R Carpinelli, Michael E de Vries, Alana Auden, Tariq Butt, Zihao Deng, Darren D Partridge, Lee B Miles, Smitha R Georgy, Jody J Haigh, Charbel Darido, Simone Brabletz, Thomas Brabletz, Marc P Stemmler, Sebastian Dworkin, Stephen M Jane

Journal article  |  2020  |  Disease Models and Mechanisms

Cleft lip and palate are common birth defects resulting from failure of the facial processes to fuse during development. The mamma..

Targeted Therapy Against the Cell of Origin in Cutaneous Squamous Cell Carcinoma

Stephen J Goldie, Ginevra Chincarini, Charbel Darido

Journal article  |  2019  |  International Journal of Molecular Sciences

mTOR Signalling in Head and Neck Cancer: Heads Up

Fiona H Tan, Yuchen Bai, Pierre Saintigny, Charbel Darido

Journal article  |  2019  |  Cells

Loss of GRHL3 leads to TARC/CCL17-mediated keratinocyte proliferation in the epidermis

Stephen J Goldie, Denny L Cottle, Fiona H Tan, Suraya Roslan, Seema Srivastava, Rhys Brady, Darren D Partridge, Alana Auden, Ian M Smyth, Stephen M Jane, Sebastian Dworkin, Charbel Darido

Journal article  |  2018  |  CELL DEATH & DISEASE

Stage-dependent therapeutic efficacy in PI3K/mTOR-driven squamous cell carcinoma of the skin

Charbel Darido, Smitha R Georgy, Carleen Cullinane, Darren D Partridge, Rachael Walker, Seema Srivastava, Suraya Roslan, Marina R Carpinelli, Sebastian Dworkin, Richard B Pearson, Stephen M Jane

Journal article  |  2018  |  Cell Death & Differentiation

Mis-expression of grainyhead-like transcription factors in zebrafish leads to defects in enveloping layer (EVL) integrity, cellular morphogenesis and axial extension

Lee B Miles, Charbel Darido, Jan Kaslin, Joan K Heath, Stephen M Jane, Sebastian Dworkin

Journal article  |  2017  |  Scientific Reports

Alternative splicing and start sites: Lessons from the Grainyhead-like family

Lee B Miles, Sebastian Dworkin, Charbel Darido

Journal article  |  2017  |  Developmental Biology

Long-Lived Epidermal Cancer-Initiating Cells

Marina Youssef, Andrew Cuddihy, Charbel Darido

Journal article  |  2017  |  International Journal of Molecular Sciences

Grainyhead-like 3 (Grhl3) Deficiency in Brain Leads to Altered Locomotor Activity and Decreased Anxiety-Like Behaviors in Aged Mice

Sebastian Dworkin, Alana Auden, Darren D Partridge, Maria Daglas, Robert L Medcalf, Theo Mantamadiotis, Smitha R Georgy, Charbel Darido, Stephen M Jane, Stephen B Ting

Journal article  |  2017  |  Developmental Neurobiology

The role of barrier genes in epidermal malignancy

C Darido, SR Georgy, SM Jane

Journal article  |  2016  |  Oncogene