Dr.Carmine Onofrillo received his academic education from the university of Bologna, awarding a bachelor’s degree in biology, a master’s degree in molecular biology and a PhD in oncology and experimental pathology. He obtained a post doctorate position at the department of experimental, diagnostic and specialty medicine of the university of Bologna at the Sant’ Orsola Polyclinic to study the relationship between ribosome biogenesis and cell cycle regulation in cancer.
He moved in Melbourne to work in the field of advanced tissue engineering. Dr. Onofrillo is part of a multidisciplinary team working at the Biofab3D at the Saint Vincent’s Hospital of Melbourne, his studies are focused on the induction and characterization of stem cells differentiation in a 3D bioprinted environment with the goal to regenerate damaged tissues.
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Carmine Onofrillo's selected work
Biofabrication of human articular cartilage: a path towards the development of a clinical ..
Free-form co-axial bioprinting of a gelatin methacryloyl bio-ink by direct in situ photo-c..
Displaying the most recent project by Carmine Onofrillo.
Displaying the 24 most recent scholarly works by Carmine Onofrillo.
Concise review: Human articular cartilage repair: Sources and detection of cytotoxicity and genotoxicity in photo-crosslinkable hydrogel bioscaffolds
Cheryl Lee, Cathal D O'Connell, Carmine Onofrillo, Peter FM Choong, Claudia Di Bella, Serena Duchi
Journal article | 2019 | STEM CELLS TRANSLATIONAL MEDICINE
Three-dimensional biofabrication using photo-crosslinkable hydrogel bioscaffolds has the potential to revolutionize the need for t..
Evaluation of sterilisation methods for bio-ink components: gelatin, gelatin methacryloyl, hyaluronic acid and hyaluronic acid methacryloyl
Cathal D O'Connell, Carmine Onofrillo, Serena Duchi, Xin Li, Yifan Zhang, Peilin Tian, Lanyita Lu, Anna Trengove, Anita Quigley, Sanjeev Gambhir, Afsaneh Khansari, Tajanka Mladenovska, Andrea O'Connor, Claudia Di Bella, Peter F Choong, Gordon G Wallace
Journal article | 2019 | Biofabrication
Reliable and scalable sterilisation of hydrogels is critical to the clinical translation of many biofabrication approaches, such a..
Alternative Overexpression of NRF2 or MYC Defines a Subgroup of Poor Prognosis Acute Myeloid Leukemia and Suggests a Novel Therapeutic Strategy By Combined Bromodomain Inhibition and Forced NRF2 Pathway Activation
Giorgia Simonetti, Samantha Bruno, Carmine Onofrillo, Cristina Papayannidis, Giovanni Marconi, Michele Cavo, Lorenzo Montanaro, Giovanni Martinelli
Conference Proceedings | 2018 | Blood
BROMODOMAIN INHIBITION TARGETS ACUTE MYELOID LEUKEMIA CELLS UNDER HYPOXIA AND ALTERS THE REGULATION OF KEAP1/NRF2 PATHWAY AT TRANSCRIPTIONAL, TRANSLATIONAL AND POST-TRANSLATIONAL LEVEL
G Simonetti, S Bruno, C Onofrillo, C Papayannidis, G Marconi, M Cavo, L Montanaro, G Martinelli
Conference Proceedings | 2018 | HAEMATOLOGICA
Design, Fabrication and Validation of a Precursor Pulsed Electromagnetic Field Device for Bone Fracture Repair.
Christian Daish, Romane Blanchard, Serena Duchi, Carmine Onofrillo, Cheryl Augustine, Kate Fox, Peter Pivonka, Elena Pirogova
Journal article | 2018 | 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
Pulsed electromagnetic field (PEMF) stimulation has been utilized in the medical field since the early 20th century. A number of t..
Tailoring the mechanical properties of gelatin methacryloyl hydrogels through manipulation of the photocrosslinking conditions
Cathal D O'Connell, Binbin Zhang, Carmine Onofrillo, Serena Duchi, Romane Blanchard, Anita Quigley, Justin Bourke, Sanjeev Gambhir, Robert Kapsa, Claudia Di Bella, Peter Choong, Gordon G Wallace
Journal article | 2018 | Soft Matter
In situ handheld three-dimensional bioprinting for cartilage regeneration
Claudia Di Bella, Serena Duchi, Cathal D O'Connell, Romane Blanchard, Cheryl Augustine, Zhilian Yue, Fletcher Thompson, Christopher Richards, Stephen Beirne, Carmine Onofrillo, Sebastien H Bauquier, Stewart D Ryan, Peter Pivonka, Gordon G Wallace, Peter F Choong
Journal article | 2018 | Journal of Tissue Engineering and Regenerative Medicine
Bromodomain Inhibition Is Effective Against Acute Myeloid Leukemia Cells Under Hypoxia and Induces Genome-Dependent Metabolic Perturbations
Giorgia Simonetti, Samantha Bruno, Carmine Onofrillo, Marco Malferrari, Cristina Papayannidis, Giovanni Marconi, Michele Cavo, Stefania Rapino, Lorenzo Montanaro, Giovanni Martinelli
Conference Proceedings | 2017 | BLOOD
Handheld Co-Axial Bioprinting: Application to in situ surgical cartilage repair
Serena Duchi, Carmine Onofrillo, Cathal D O'Connell, Romane Blanchard, Cheryl Augustine, Anita F Quigley, Robert MI Kapsa, Peter Pivonka, Gordon Wallace, Claudia Di Bella, Peter FM Choong
Journal article | 2017 | SCIENTIFIC REPORTS
Epigenetic up-regulation of ribosome biogenesis and more aggressive phenotype triggered by the lack of the histone demethylase JHDM1B in mammary epithelial cells
Alice Galbiati, Marianna Penzo, Maria Giulia Bacalini, Carmine Onofrillo, Ania Naila Guerrieri, Paolo Garagnani, Claudio Franceschi, Davide Trere, Lorenzo Montanaro
Journal article | 2017 | Oncotarget
Cap-independent protein synthesis is enhanced by betaine under hypertonic conditions
Domenica Carnicelli, Valentina Arfilli, Carmine Onofrillo, Roberta R Alfieri, Pier Giorgio Petronini, Lorenzo Montanaro, Maurizio Brigotti
Journal article | 2017 | Biochemical and Biophysical Research Communications
Therapeutic dosages of aspirin counteract the IL-6 induced pro-tumorigenic effects by slowing down the ribosome biogenesis rate
Elisa Brighenti, Ferdinando Antonino Giannone, Francesca Fornari, Carmine Onofrillo, Marzia Govoni, Lorenzo Montanaro, Davide Trere, Massimo Derenzini
Journal article | 2016 | Oncotarget
p53-dependent and p53-independent anticancer activity of a new indole derivative in human osteosarcoma cells
C Cappadone, C Stefanelli, E Malucelli, M Zini, C Onofrillo, A Locatelli, M Rambaldi, A Sargenti, L Merolle, G Farruggia, A Graziadio, L Montanaro, S Iotti
Journal article | 2015 | Biochemical and Biophysical Research Communications
Honours, Awards and Fellowships
Abroad Research experience Fellowship
Post Doctorate Fellow
Surgery - St Vincent'S Hospital
Australian Society Of Biomaterials And Tissue Engineering
Arc Center Of Excellence For Electromaterial Science
Doctorate in Oncology and experimental pathology
University of Bologna
Molecular and Cellular Biology
University of Bologna
University of Bologna