Carmine Onofrillo

Formation of alginate microspheres prepared by optimized microfluidics parameters for high encapsulation of bioactive molecules

Lilith M Caballero Aguilar, Serena Duchi, Carmine Onofrillo, Cathal D O'Connell, Claudia Di Bella, Simon E Moulton

Journal article  |  2021  |  Journal of Colloid and Interface Science

Drug delivery systems such as microspheres have shown potential in releasing biologicals effectively for tissue engineering applic..

Characterization of Polycaprolactone Nanohydroxyapatite Composites with Tunable Degradability Suitable for Indirect Printing

Stephanie E Doyle, Lauren Henry, Ellen McGennisken, Carmine Onofrillo, Claudia Di Bella, Serena Duchi, Cathal D O'Connell, Elena Pirogova

Journal article  |  2021  |  Polymers

Degradable bone implants are designed to foster the complete regeneration of natural tissue after large-scale loss trauma. Polycap..

FLASH: Fluorescently LAbelled Sensitive Hydrogel to monitor bioscaffolds degradation during neocartilage generation

Carmine Onofrillo, Serena Duchi, Sam Francis, Cathal D O'Connell, Lilith M Caballero Aguilar, Stephanie Doyle, Zhilian Yue, Gordon G Wallace, Peter F Choong, Claudia Di Bella

Journal article  |  2021  |  Biomaterials

Regenerative therapies based on photocrosslinkable hydrogels and stem cells are of growing interest in the field of cartilage repa..

DKC1 Overexpression Induces a More Aggressive Cellular Behavior and Increases Intrinsic Ribosomal Activity in Immortalized Mammary Gland Cells

Ania Naila Guerrieri, Federico Zacchini, Carmine Onofrillo, Sara Di Viggiano, Marianna Penzo, Alessio Ansuini, Ilaria Gandin, Yuko Nobe, Masato Taoka, Toshiaki Isobe, Davide Trere, Lorenzo Montanaro

Journal article  |  2020  |  Cancers

Dyskerin is a nucleolar protein involved in the small nucleolar RNA (snoRNA)-guided pseudouridylation of specific uridines on ribo..

Free-form co-axial bioprinting of a gelatin methacryloyl bio-ink by direct in situ photo-crosslinking during extrusion

CD O'Connell, S Konate, C Onofrillo, R Kapsa, C Baker, S Duchi, T Eekel, Z Yue, S Beirne, G Barnsley, C Di Bella, PF Choong, GG Wallace

Journal article  |  2020  |  Bioprinting

3D bioprinting is an emerging technology for arranging cells and biomaterials in 3D, with the goal to develop functional substitut..

Bioprinting Stem Cells in Hydrogel for In Situ Surgical Application: A Case for Articular Cartilage.

Serena Duchi, Carmine Onofrillo, Cathal O'Connell, Gordon G Wallace, Peter Choong, Claudia Di Bella

Journal article  |  2020  |  Methods in molecular biology (Clifton, N.J.)

Three-dimensional (3D) bioprinting is driving major innovations in the area of cartilage tissue engineering. As an alternative to ..

Characterizing Bioinks for Extrusion Bioprinting: Printability and Rheology.

Cathal O'Connell, Junxiang Ren, Leon Pope, Yifan Li, Anushree Mohandas, Romane Blanchard, Serena Duchi, Carmine Onofrillo

Journal article  |  2020  |  Methods in molecular biology (Clifton, N.J.)

In recent years, new technologies based on 3D bioprinting have emerged as ideal tools with which to arrange cells and biomaterials..

Concise review: Human articular cartilage repair: Sources and detection of cytotoxicity and genotoxicity in photo-crosslinkable hydrogel bioscaffolds

Cheryl Lee, Cathal D O'Connell, Carmine Onofrillo, Peter FM Choong, Claudia Di Bella, Serena Duchi

Journal article  |  2019  |  STEM CELLS TRANSLATIONAL MEDICINE

Three-dimensional biofabrication using photo-crosslinkable hydrogel bioscaffolds has the potential to revolutionize the need for t..

Evaluation of sterilisation methods for bio-ink components: gelatin, gelatin methacryloyl, hyaluronic acid and hyaluronic acid methacryloyl

Cathal D O'Connell, Carmine Onofrillo, Serena Duchi, Xin Li, Yifan Zhang, Peilin Tian, Lanyita Lu, Anna Trengove, Anita Quigley, Sanjeev Gambhir, Afsaneh Khansari, Tajanka Mladenovska, Andrea O'Connor, Claudia Di Bella, Peter F Choong, Gordon G Wallace

Journal article  |  2019  |  Biofabrication

Reliable and scalable sterilisation of hydrogels is critical to the clinical translation of many biofabrication approaches, such a..

Protocols for Culturing and Imaging a Human Ex Vivo Osteochondral Model for Cartilage Biomanufacturing Applications

Serena Duchi, Stephanie Doyle, Timon Eekel, Cathal D O'Connell, Cheryl Augustine, Peter Choong, Carmine Onofrillo, Claudia Di Bella

Journal article  |  2019  |  MATERIALS