Zachery Moore

An altered glial phenotype in the NL3(R451C) mouse model of autism

Samantha M Matta, Zachery Moore, Frederick Rohan Walker, Elisa L Hill-Yardin, Peter J Crack

Journal article  |  2020  |  SCIENTIFIC REPORTS

Autism Spectrum Disorder (ASD; autism) is a neurodevelopmental disorder characterised by deficits in social communication, and res..

Abrogation of type-I interferon signalling alters the microglial response to A beta(1-42)

Zachery Moore, Frank Mobilio, Frederick R Walker, Juliet M Taylor, Peter J Crack

Journal article  |  2020  |  SCIENTIFIC REPORTS

Neuroinflammation and accompanying microglial dysfunction are now appreciated to be involved in Alzheimer's disease (AD) pathogene..

The involvement of microglia in Alzheimer's disease: a new dog in the fight

Zachery Moore, Juliet M Taylor, Peter J Crack

Journal article  |  2019  |  BRITISH JOURNAL OF PHARMACOLOGY

First described clinically in 1906, Alzheimer's disease (AD) is the most common neurodegenerative disease and form of dementia wor..

Type-I interferon pathway in neuroinflammation and neurodegeneration: focus on Alzheimer's disease

Juliet M Taylor, Zachery Moore, Myles R Minter, Peter J Crack

Journal article  |  2018  |  JOURNAL OF NEURAL TRANSMISSION

Past research in Alzheimer's disease (AD) has largely been driven by the amyloid hypothesis; the accompanying neuroinflammation se..

Deletion of the type-1 interferon receptor in APP(SWE)/PS1(Delta E9) mice preserves cognitive function and alters glial phenotype

Myles R Minter, Zachery Moore, Moses Zhang, Kate M Brody, Nigel C Jones, Sandy R Shultz, Juliet M Taylor, Peter J Crack

Journal article  |  2016  |  ACTA NEUROPATHOLOGICA COMMUNICATIONS

A neuro-inflammatory response is evident in Alzheimer's disease (AD), yet the precise mechanisms by which neuro-inflammation influ..