Jennifer Juno

Phenotypic and functional characterization of pharmacologically expanded Vγ9Vδ2 T cells in pigtail macaques

IM Barber-Axthelm, KM Wragg, R Esterbauer, TH Amarasena, VRB Barber-Axthelm, AK Wheatley, AM Gibbon, SJ Kent, JA Juno

Journal article  |  2023  |  iScience

While gaining interest as treatment for cancer and infectious disease, the clinical efficacy of Vγ9Vδ2 T cell-based immunotherapeu..

SARS-CoV-2 breakthrough infection induces rapid memory and de novo T cell responses

Marios Koutsakos, Arnold Reynaldi, Wen Shi Lee, Julie Nguyen, Thakshila Amarasena, George Taiaroa, Paul Kinsella, Kwee Chin Liew, Thomas Tran, Helen E Kent, Hyon-Xhi Tan, Louise C Rowntree, Thi HO Nguyen, Paul G Thomas, Katherine Kedzierska, Jan Petersen, Jamie Rossjohn, Deborah A Williamson, David Khoury, Miles P Davenport, et al.

Journal article  |  2023  |  Immunity

Phenotypic and functional characteristics of highly differentiated CD57( )NKG2C( ) NK cells in HIV-1-infected individuals

Anne B Kristensen, Kathleen Wragg, Hillary Vanderven, Wen Shi Lee, Julie Silvers, Helen E Kent, Michael D Grant, Anthony D Kelleher, Jennifer A Juno, Stephen J Kent, Matthew S Parsons

Journal article  |  2022  |  CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Natural killer (NK) cells are important anti-viral effector cells. The function and phenotype of the NK cells that constitute an i..

The magnitude and timing of recalled immunity after breakthrough infection is shaped by SARS-CoV-2 variants

Marios Koutsakos, Wen Shi Lee, Arnold Reynaldi, Hyon-Xhi Tan, Grace Gare, Paul Kinsella, Kwee Chin Liew, George Taiaroa, Deborah A Williamson, Helen E Kent, Eva Stadler, Deborah Cromer, David S Khoury, Adam K Wheatley, Jennifer A Juno, Miles P Davenport, Stephen J Kent

Journal article  |  2022  |  IMMUNITY

Vaccination against SARS-CoV-2 protects from infection and improves clinical outcomes in breakthrough infections, likely reflectin..

Anti-PEG Antibodies Boosted in Humans by SARS-CoV-2 Lipid Nanoparticle mRNA Vaccine

Yi Ju, Wen Shi Lee, Emily H Pilkington, Hannah G Kelly, Shiyao Li, Kevin J Selva, Kathleen M Wragg, Kanta Subbarao, Thi HO Nguyen, Louise C Rowntree, Lilith F Allen, Katherine Bond, Deborah A Williamson, Nghia P Truong, Magdalena Plebanski, Katherine Kedzierska, Siddhartha Mahanty, Amy W Chung, Frank Caruso, Adam K Wheatley, et al.

Journal article  |  2022  |  ACS NANO

Humans commonly have low level antibodies to poly(ethylene) glycol (PEG) due to environmental exposure. Lipid nanoparticle (LNP) m..

Interplay of infection and vaccination in long-term protection from COVID-19.

Hyon-Xhi Tan, Jennifer A Juno

Journal article  |  2022  |  Lancet Infect Dis

Cutting Edge: SARS-CoV-2 Infection Induces Robust Germinal Center Activity in the Human Tonsil

Hyon-Xhi Tan, Kathleen M Wragg, Hannah G Kelly, Robyn Esterbauer, Benjamin J Dixon, Jillian SY Lau, Katie L Flanagan, Carolien E van de Sandt, Katherine Kedzierska, James H McMahon, Adam K Wheatley, Jennifer A Juno, Stephen J Kent

Journal article  |  2022  |  JOURNAL OF IMMUNOLOGY

Understanding the generation of immunity to SARS-CoV-2 in lymphoid tissues draining the site of infection has implications for imm..

Disentangling the relative importance of T cell responses in COVID-19: leading actors or supporting cast?

Stephen J Kent, David S Khoury, Arnold Reynold, Jennifer A Juno, Adam K Wheatley, Eva Stadler, E John Wherry, James Triccas, Sarah C Sasson, Deborah Cromer, Miles P Davenport

Journal article  |  2022  |  NATURE REVIEWS IMMUNOLOGY

The rapid development of multiple vaccines providing strong protection from severe acute respiratory syndrome coronavirus 2 (SARS-..

COVID-19 vaccines in the age of the delta variant.

Adam K Wheatley, Jennifer A Juno

Journal article  |  2022  |  Lancet Infect Dis

Establishment and recall of SARS-CoV-2 spike epitope-specific CD4( ) T cell memory

Kathleen M Wragg, Wen Shi Lee, Marios Koutsakos, Hyon-Xhi Tan, Thakshila Amarasena, Arnold Reynaldi, Grace Gare, Penny Konstandopoulos, Kirsty R Field, Robyn Esterbauer, Helen E Kent, Miles P Davenport, Adam K Wheatley, Stephen J Kent, Jennifer A Juno

Journal article  |  2022  |  NATURE IMMUNOLOGY

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and vaccination elicit CD4+ T cell responses to the spike p..