Jennifer Juno

Evolution of immune responses to SARS-CoV-2 in mild-moderate COVID-19.

Adam K Wheatley, Jennifer A Juno, Jing J Wang, Kevin J Selva, Arnold Reynaldi, Hyon-Xhi Tan, Wen Shi Lee, Kathleen M Wragg, Hannah G Kelly, Robyn Esterbauer, Samantha K Davis, Helen E Kent, Francesca L Mordant, Timothy E Schlub, David L Gordon, David S Khoury, Kanta Subbarao, Deborah Cromer, Tom P Gordon, Amy W Chung, et al.

Journal article  |  2021  |  Nature Communications

The durability of infection-induced SARS-CoV-2 immunity has major implications for reinfection and vaccine development. Here, we s..

Translating viral vaccines into immunity.

Jennifer A Juno, Shelby L O'Connor

Journal article  |  2021  |  Science

Screening and development of monoclonal antibodies for identification of ferret T follicular helper cells.

Wenbo Jiang, Julius Wong, Hyon-Xhi Tan, Hannah G Kelly, Paul G Whitney, Ian Barr, Daniel S Layton, Stephen J Kent, Adam K Wheatley, Jennifer A Juno

Journal article  |  2021  |  Scientific Reports

The ferret is a key animal model for investigating the pathogenicity and transmissibility of important human viruses, and for the ..

Aggregation by peptide conjugation rescues poor immunogenicity of the HA stem

Wenbo Jiang, Emily H Pilkington, Hannah G Kelly, Hyon-Xhi Tan, Jennifer A Juno, Adam K Wheatley, Stephen J Kent

Journal article  |  2020  |  PLoS One

Influenza virus infection is a global public health threat. Current seasonal influenza vaccines are efficacious only when vaccine ..

Plasma ACE2 activity is persistently elevated following SARS-CoV-2 infection: implications for COVID-19 pathogenesis and consequences

Sheila Patel, Jennifer Juno, Wen Shi Lee, Kathleen Wragg, Mark Hogarth, Stephen Kent, Louise Burrell

Journal article  |  2020

COVID-19 causes persistent endothelial inflammation, lung and cardiovascular complications. SARS-CoV-2 utilises the catalytic site..

Characterization of MAIT cells in Mauritian cynomolgus macaques (MCM) SIV/Mtb co-infection

Alexis Balgeman, Amy L Ellis, Erica Larson, Mark A Rodgers, Cassaundra Ameel, Tonilynn Baranowski, Jen Juno, Charles A Scanga, Shelby L O'Connor

Conference Proceedings  |  2020  |  JOURNAL OF MEDICAL PRIMATOLOGY

Suboptimal SARS-CoV-2-specific CD8( ) T cell response associated with the prominent HLA-A*02:01 phenotype

Jennifer R Habel, Thi HO Nguyen, Carolien E van de Sandt, Jennifer A Juno, Priyanka Chaurasia, Kathleen Wragg, Marios Koutsakos, Luca Hensen, Xiaoxiao Jia, Brendon Chua, Wuji Zhang, Hyon-Xhi Tan, Katie L Flanagan, Denise L Doolan, Joseph Torresi, Weisan Chen, Linda M Wakim, Allen C Cheng, Peter C Doherty, Jan Petersen, et al.

Journal article  |  2020  |  Proceedings of the National Academy of Sciences of USA

An improved understanding of human T cell-mediated immunity in COVID-19 is important for optimizing therapeutic and vaccine strate..

Evolution of immunity to SARS-CoV-2

Adam Wheatley, Jennifer Juno, Jing Wang, Kevin Selva, Arnold Reynaldi, Hyon-Xhi Tan, Wen Shi Lee, Kathleen Wragg, Hannah Kelly, Robyn Esterbauer, Samantha Davis, Helen Kent, Francesca Mordant, Timothy Schlub, David Gordon, David Khoury, Kanta Subbarao, Deborah Cromer, Tom Gordon, Amy Chung, et al.

Journal article  |  2020

The durability of infection-induced SARS-CoV-2 immunity has major implications for public health mitigation and vaccine developmen..

Immune profiling of influenza-specific B- and T-cell responses in macaques using flow cytometry-based assays

Marios Koutsakos, Toshiki Sekiya, Brendon Y Chua, Hoang Oanh Nguyen Thi, Adam K Wheatley, Jennifer A Juno, Marumi Ohno, Naoki Nomura, Yuki Ohara, Tomohiro Nishimura, Masafumi Endo, Saori Suzuki, Hirohito Ishigaki, Misako Nakayama, Cong T Nguyen, Yasushi Itoh, Masashi Shingai, Kazumasa Ogasawara, Yoichiro Kino, Stephen J Kent, et al.

Journal article  |  2020  |  Immunology and Cell Biology

Influenza remains a significant global public health burden, despite substantial annual vaccination efforts against circulating vi..

Prime-boost protein subunit vaccines against SARS-CoV-2 are highly immunogenic in mice and macaques

Hyon-Xhi Tan, Jennifer Juno, Wen Shi Lee, Isaac Barber-Axthelm, Hannah Kelly, Kathleen Wragg, Robyn Esterbauer, Thakshila Amarasena, Francesca Mordant, Kanta Subbarao, Stephen Kent, Adam Wheatley

Journal article  |  2020

Summary SARS-CoV-2 vaccines are advancing into human clinical trials, with emphasis on eliciting high titres of neutralising antib..