Andrew Cox

Imaging Mass Spectrometry Reveals Tumor Metabolic Heterogeneity

Yang Zhang, Christelle Guillermier, Thomas De Raedt, Andrew G Cox, Ophelia Maertens, Dean Yimlamai, Mingyue Lun, Adam Whitney, Richard L Maas, Wolfram Goessling, Karen Cichowski, Matthew L Steinhauser

Journal article  |  2020  |  iScience

Mutations in RABL3 alter KRAS prenylation and are associated with hereditary pancreatic cancer.

Sahar Nissim, Ignaty Leshchiner, Joseph Mancias, Matthew Greenblatt, Ophelia Maertens, Christopher Cassa, Jill Rosenfeld, Andrew Cox, John Hedgepeth, Julia Wucherpfennig, Andrew Kim, Jake Henderson, Patrick Gonyo, Anthony Brandt, Ellen Lorimer, Bethany Unger, Gad Getz, Shamil Sunyaev, Wade Harper, Karen Cichowski, et al.

Conference Proceedings  |  2020  |  MOLECULAR CANCER RESEARCH

YAP Regulates Hematopoietic Stem Cell Formation in Response to the Biomechanical Forces of Blood Flow

Vanessa Lundin, Wade W Sugden, Lindsay N Theodore, Patricia M Sousa, Areum Han, Stephanie Chou, Paul J Wrighton, Andrew G Cox, Donald E Ingber, Wolfram Goessling, George Q Daley, Trista E North

Journal article  |  2020  |  Developmental Cell

Hematopoietic stem and progenitor cells (HSPCs), first specified from hemogenic endothelium (HE) in the ventral dorsal aorta (VDA)..

Mutations in RABL3 alter KRAS prenylation and are associated with hereditary pancreatic cancer

Sahar Nissim, Ignaty Leshchiner, Joseph D Mancias, Matthew B Greenblatt, Ophelia Maertens, Christopher A Cassa, Jill A Rosenfeld, Andrew G Cox, John Hedgepeth, Julia I Wucherpfennig, Andrew J Kim, Jake E Henderson, Patrick Gonyo, Anthony Brandt, Ellen Lorimer, Bethany Unger, Jeremy W Prokop, Jerry R Heidel, Xiao-Xu Wang, Chinedu I Ukaegbu, et al.

Journal article  |  2019  |  Nature Genetics

Estrogen Activation of G-Protein-Coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-Kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes

Saireudee Chaturantabut, Arkadi Shwartz, Kimberley J Evason, Andrew G Cox, Kyle Labella, Arnout G Schepers, Song Yang, Mariana Acuna, Yariv Houvras, Liliana Mancio-Silva, Shannon Romano, Daniel A Gorelick, David E Cohen, Leonard Zon, Sangeeta N Bhatia, Trista E North, Wolfram Goessling

Journal article  |  2019  |  Gastroenterology

Yap1 promotes sprouting and proliferation of lymphatic progenitors downstream of Vegfc in the zebrafish trunk

Lin Grimm, Hiroyuki Nakajima, Smrita Chaudhury, Neil Bower, Kazuhide S Okuda, Andrew G Cox, Natasha L Harvey, Katarzyna Koltowska, Naoki Mochizuki, Benjamin M Hogan

Journal article  |  2019  |  eLife

Dissecting metabolism using zebrafish models of disease

Talhah M Salmi, Vicky WT Tan, Andrew G Cox

Journal article  |  2019  |  Biochemical Society Transactions

Yap regulates glucose utilization and sustains nucleotide synthesis to enable organ growth

Andrew G Cox, Allison Tsomides, Dean Yimlamai, Katie L Hwang, Joel Miesfeld, Giorgio G Galli, Brendan H Fowl, Michael Fort, Kimberly Y Ma, Mark R Sullivan, Aaron M Hosios, Erin Snay, Min Yuan, Kristin K Brown, Evan C Lien, Sagar Chhangawala, Matthew L Steinhauser, John M Asara, Yariv Houvras, Brian Link, et al.

Journal article  |  2018  |  The EMBO Journal

Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis

Andrew G Cox, Allison Tsomides, Andrew J Kim, Diane Saunders, Katie L Hwang, Kimberley J Evason, Jerry Heidel, Kristin K Brown, Min Yuan, Evan C Lien, Byung Cheon Lee, Sahar Nissim, Bryan Dickinson, Sagar Chhangawala, Christopher J Chang, John M Asara, Yariv Houvras, Vadim N Gladyshev, Wolfram Goessling

Journal article  |  2016  |  Proceedings of the National Academy of Sciences of the United States of America

Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth

Andrew G Cox, Katie L Hwang, Kristin K Brown, Kimberley J Evason, Sebastian Beltz, Allison Tsomides, Keelin O'Connor, Giorgio G Galli, Dean Yimlamai, Sagar Chhangawala, Min Yuan, Evan C Lien, Julia Wucherpfennig, Sahar Nissim, Akihiro Minami, David E Cohen, Fernando D Camargo, John M Asara, Yariv Houvras, Didier YR Stainier, et al.

Journal article  |  2016  |  NATURE CELL BIOLOGY