Jane Kaye

Dynamic Consent: An Evaluation and Reporting Framework

Megan Prictor, Megan Lewis, Ainsley Newson, Matilda Haas, Sachiko Baba, Hannah Kim, Minori Kokado, Jusaku Minari, Fruzsina Molnar-Gabor, Beverley Yamamoto, Jane Kaye, Harriet Teare

Journal article  |  2020  |  Journal of Empirical Research on Human Research Ethics

Dynamic consent (DC) is an approach to consent that enables people, through an interactive digital interface, to make granular dec..

Australian Aboriginal and Torres Strait Islander Collections of Genetic Heritage: The Legal, Ethical and Practical Considerations of a Dynamic Consent Approach to Decision Making.

Megan Prictor, Sharon Huebner, Harriet Teare, Luke Burchill, Jane Kaye

Journal article  |  2020  |  The Journal of Law, Medicine and Ethics

The article considers whether a Dynamic Consent (DC) approach might be adopted with cultural leadership to support communication, ..

A Reference Map of Potential Determinants for the Human Serum Metabolome

Noam Bar, Tal Korem, Omer Weissbrod, David Zeevi, Daphna Rothschild, Sigal Leviatan, Noa Kosower, Maya Lotan-Pompan, Adina Weinberger, Caroline I Le Roy, Cristina Menni, Alessia Visconti, Mario Falchi, Tim D Spector, undefined IMI DIRECT consortium, Jerzy Adamski, Paul W Franks, Oluf Pedersen, Eran Segal

Journal article  |  2020  |  Nature

The serum metabolome contains a plethora of biomarkers and causative agents of various diseases, some of which are endogenously pr..

A Factorial Survey Investigating the Effect of Disclosing Parental Intellectual Disability on Risk Assessments by Children's Social Workers in Child Safeguarding Scenarios

Ameeta Retzer, Jane Kaye, Ron Gray

Journal article  |  2020  |  The British Journal of Social Work

Literature suggests that, as parents, people with intellectual disabilities experience disproportionately high rates of child remo..

Clinical Decision Support Systems and Medico-Legal Liability in Recall and Treatment: A Fresh Examination

Megan Prictor, Mark Taylor, Jane Kaye, Jon Emery, Craig Nelson, Jo Manski-Nankervis

Journal article  |  2020  |  Journal of law and medicine

Clinical decision support systems (CDSSs) provide a valuable tool for clinicians to aid in the care of patients with chronic disea..

Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration.

Henry R Wilman, Constantinos A Parisinos, Naeimeh Atabaki-Pasdar, Matt Kelly, E Louise Thomas, Stefan Neubauer, undefined IMI DIRECT Consortium, Anubha Mahajan, Aroon D Hingorani, Riyaz S Patel, Harry Hemingway, Paul W Franks, Jimmy D Bell, Rajarshi Banerjee, Hanieh Yaghootkar

Journal article  |  2019  |  Journal of Hepatology

BACKGROUND & AIMS: Excess liver iron content is common and is linked to the risk of hepatic and extrahepatic diseases. We aimed to..

Sharing data for future research-engaging participants' views about data governance beyond the original project: a DIRECT Study

Nisha Shah, Victoria Coathup, Harriet Teare, Ian Forgie, Giuseppe Nicola Giordano, Tue Haldor Hansen, Lenka Groeneveld, Michelle Hudson, Ewan Pearson, Hartmut Ruetten, Jane Kaye

Journal article  |  2019  |  Genetics in Medicine

Motivations for data sharing-views of research participants from four European countries: A DIRECT study

Nisha Shah, Victoria Coathup, Harriet Teare, Ian Forgie, Giuseppe Nicola Giordano, Tue Haldor Hansen, Lenka Groeneveld, Michelle Hudson, Ewan Pearson, Hartmut Ruetten, Jane Kaye

Journal article  |  2019  |  European Journal of Human Genetics

Health Data Linkage for UK Public Interest Research: Key Obstacles and Solutions.

Miranda Jane Mourby, James Doidge, Kerina H Jones, Stergios Aidinlis, Hannah Smith, Jessica Bell, Ruth Gilbert, Peter Dutey-Magni, Jane Kaye

Journal article  |  2019  |  International Journal for Population Data Science

Introduction: Analysis of linked health data can generate important, even life-saving, insights into population health. Yet obstac..

Low-frequency variation in TP53 has large effects on head circumference and intracranial volume

Simon Haworth, Chin Yang Shapland, Caroline Hayward, Bram P Prins, Janine F Felix, Carolina Medina-Gomez, Fernando Rivadeneira, Carol Wang, Tarunveer S Ahluwalia, Martine Vrijheid, Monica Guxens, Jordi Sunyer, Ioanna Tachmazidou, Klaudia Walter, Valentina Iotchkova, Andrew Jackson, Louise Cleal, Jennifer Huffmann, Josine L Min, Laerke Sass, et al.

Journal article  |  2019  |  Nature Communications