Amit Kumar

Prevalence and Spectrum of Germline Mutations in Children with High-Risk Cancer

N Fuentes-Bolanos, M Warby, P Barahona, A Sherstyuk, M Cowley, P Ekert, J Kirk, DA Khuong-Quang, K Amit, L Lau, C Mayoh, G Marshall, E Mould, TA O'Brien, M Pinese, D Thomas, V Tyrrell, D Ziegler, M Harber, KM Tucker

Conference Proceedings  |  2019  |  PEDIATRIC BLOOD & CANCER

Zero Childhood Cancer: A comprehensive precision medicine platform for children with high-risk cancer

Emily V Mould, Loretta Lau, Greg Arndt, Paulette Barahona, Mark J Cowley, Paul Ekert, Tim Failes, Jamie Fletcher, Andrew Gifford, Dylan Grebert-Wade, Michelle Haber, Alvin Kamili, Amit Kumar, Richard B Lock, Glenn M Marshall, Chelsea Mayoh, Murray Norris, Tracey O'Brien, Dong Anh Khuong Quang, Patrick Strong, et al.

Conference Proceedings  |  2019  |  Clinical Research (Excluding Clinical Trials)

Comparative analysis of milk microRNA in the therian lineage highlights the evolution of lactation

Christophe Lefevre, Pooja Venkat, Amit Kumar, Vengamanaidu Modepalli, Kevin R Nicholas

Journal article  |  2019  |  Reproduction, Fertility and Development

CNspector: a web-based tool for visualisation and clinical diagnosis of copy number variation from next generation sequencing

John F Markham, Satwica Yerneni, Georgina L Ryland, Huei San Leong, Andrew Fellowes, Ella R Thompson, Wasanthi De Silva, Amit Kumar, Richard Lupat, Jason Li, Jason Ellul, Stephen Fox, Michael Dickinson, Anthony T Papenfuss, Piers Blombery

Journal article  |  2019  |  Scientific Reports

Next Generation Sequencing is now routinely used in the practice of diagnostic pathology to detect clinically relevant somatic and..

RESULTS OF THE ZERO CHILDHOOD CANCER INTEGRA-TM PRECISION MEDICINE PLATFORM FOR PAEDIATRIC HIGH-RISK BRAIN TUMOURS

Maria Tsoli, Loretta Lau, Paulette Barahona, Chelsea Mayoh, Tim Failes, Marie Wong, Alexandra Sherstyuk, Andrew J Gifford, Amit Kumar, Emily Mould, Caitlin Ung, Ornella Tolhurst, Anjana Gopalakrishnan, Dylan Grebert-Wade, Patrick Strong, Peter Trebilcock, Richard Lock, Vanessa Tyrrell, Toby Trahair, Katherine Tucker, et al.

Conference Proceedings  |  2019  |  NEURO-ONCOLOGY

Guiding Development of the Neonate: Lessons from Mammalia

Kevin R Nicholas, Vengama Modepalli, Ashalyn P Watt, Lyn A Hinds, Amit Kumar, Christophe Lefevre, Julie A Sharp

Book Chapter  |  2019  |  Nestle Nutrition Institute workshop series

Significantly preterm and low-birthweight (LBW) babies have diminished lung and gut development, generally fail to thrive, have in..

Overview of Fusion Detection Strategies Using Next-Generation Sequencing.

Jan Schröder, Amit Kumar, Stephen Q Wong

Book Chapter  |  2019  |  Methods in Molecular Biology

Structural gene fusion rearrangements leading to aberrant signaling are frequently detected in many cancer types. Gene fusions hav..

Integration of genomics, high throughput drug screening, and personalized xenograft models as a novel precision medicine paradigm for high risk pediatric cancer

Maria Tsoli, Carol Wadham, Mark Pinese, Tim Failes, Swapna Joshi, Emily Mould, Julia X Yin, Velimir Gayevskiy, Amit Kumar, Warren Kaplan, Paul G Ekert, Federica Saletta, Laura Franshaw, Jie Liu, Andrew Gifford, Martin A Weber, Michael Rodriguez, Richard J Cohn, Greg Arndt, Vanessa Tyrrell, et al.

Journal article  |  2018  |  Cancer Biology & Therapy

Gene expression profiling of postnatal lung development in the marsupial gray short-tailed opossum (Monodelphis domestica) highlights conserved developmental pathways and specific characteristics during lung organogenesis

Vengamanaidu Modepalli, Amit Kumar, Julie A Sharp, Norman R Saunders, Kevin R Nicholas, Christophe Lefevre

Journal article  |  2018  |  BMC Genomics

Brief Report: Potent clinical and radiological response to larotrectinib in TRK fusion-driven high-grade glioma

David S Ziegler, Marie Wong, Chelsea Mayoh, Amit Kumar, Maria Tsoli, Emily Mould, Vanessa Tyrrell, Dong-Anh Khuong-Quang, Mark Pinese, Velimir Gayevskiy, Richard J Cohn, Loretta MS Lau, Mark Reynolds, Michael C Cox, Andrew Gifford, Michael Rodriguez, Mark J Cowley, Paul G Ekert, Glenn M Marshall, Michelle Haber

Journal article  |  2018  |  British Journal of Cancer

Zero Childhood Cancer: A comprehensive precision medicine platform for children with high-risk cancer

Emily Mould, Loretta Lau, Greg Arndt, Paulette Barahona, Mark Cowley, Paul Ekert, Tim Failes, Jamie Fletcher, Andrew Gifford, Michelle Haber, Alvin Kamili, Amit Kumar, Richard Lock, Glenn Marshall, Chelsea Mayoh, Scott Mead, Murray Norris, Tracey O'Brien, Mark Pinese, Anh Khuong Quang Dong, et al.

Conference Proceedings  |  2018  |  Clinical Research (Excluding Clinical Trials)

Integrated genomics: drug screening and personalized xenograft development approach to identify precision treatments for aggressive pediatric brain tumors

Maria Tsoli, Carol Wadham, Mark Pinese, Tim Failes, Swapna Joshi, Emily Mould, Julia Yin, Velimir Gayevski, Amit Kumar, Warren Kaplan, Paul Ekert, Laura Franshaw, Andrew Gifford, Martin Weber, Michael Rodriguez, Chelsea Mayoh, Richard Cohn, Greg Arndt, Richard Lock, Vanessa Tyrrell, et al.

Conference Proceedings  |  2018  |  Clinical Research (Excluding Clinical Trials)

Transcriptome analysis of mammary epithelial cell gene expression reveals novel roles of the extracellular matrix.

Stephen S Wanyonyi, Amit Kumar, Ryan Du Preez, Christophe Lefevre, Kevin R Nicholas

Journal article  |  2017  |  Biochemistry and Biophysics Reports

BACKGROUND: The unique lactation strategy of the tammar wallaby (Macropus eugeni) has been invaluable in evaluating the role of la..

PathOS: a decision support system for reporting high throughput sequencing of cancers in clinical diagnostic laboratories

Kenneth D Doig, Andrew Fellowes, Anthony H Bell, Andrei Seleznev, David Ma, Jason Ellul, Jason Li, Maria A Doyle, Ella R Thompson, Amit Kumar, Luis Lara, Ravikiran Vedururu, Gareth Reid, Thomas Conway, Anthony T Papenfuss, Stephen B Fox

Journal article  |  2017  |  Genome Medicine

The tammar wallaby: A marsupial model to examine the timed delivery and role of bioactives in milk

Julie A Sharp, Stephen Wanyonyi, Vengama Modepalli, Ashalyn Watt, Sanjana Kuruppath, Lyn A Hinds, Amit Kumar, Helen E Abud, Christophe Lefevre, Kevin R Nicholas

Journal article  |  2017  |  General and Comparative Endocrinology