Elizabeth Hartland

IFN gamma receptor down-regulation facilitates Legionella survival in alveolar macrophages

Chao Yang, Daniel S McDermot, Shivani Pasricha, Sammy Bedoui, Laurel L Lenz, Ian R van Driel, Elizabeth L Hartland

Journal article  |  2019  |  Journal of Leukocyte Biology

Loss of O-Linked Protein Glycosylation in Burkholderia cenocepacia Impairs Biofilm Formation and Siderophore Activity and Alters Transcriptional Regulators

Cameron C Oppy, Leila Jebeli, Miku Kuba, Clare V Oates, Richard Strugnell, Laura E Edgington-Mitchell, Miguel A Valvano, Elizabeth L Hartland, Hayley J Newton, Nichollas E Scott

Journal article  |  2019  |  mSphere

O-linked protein glycosylation is a conserved feature of the Burkholderia genus. The addition of the trisaccharide β-Gal-(1,3)-α-G..

The regulation of T cell responses by cytohesins

A Solomatina, F Tolksdorf, PG Whitney, IR van Driel, EL Hartland, W Kolanus

Conference Proceedings  |  2019  |  EUROPEAN JOURNAL OF IMMUNOLOGY

IL-18R depended protection against bacterial pneumonia by pulmonary epithelial cells

V Scheiding, L Oberkircher, JW Lil, C Schmitt, AS Brown, G Ng, M Fleischmann, EL Hartland, IR van Driel, N Garbi

Conference Proceedings  |  2019  |  EUROPEAN JOURNAL OF IMMUNOLOGY

Salmonella Effectors SseK1 and SseK3 Target Death Domain Proteins in the TNF and TRAIL Signaling Pathways

Joshua PM Newson, Nichollas E Scott, Ivy Yeuk Wah Chung, Tania Wong Fok Lung, Cristina Giogha, Jiyao Gan, Nancy Wang, Richard A Strugnell, Nathaniel F Brown, Miroslaw Cygler, Jaclyn S Pearson, Elizabeth L Hartland

Journal article  |  2019  |  Molecular & Cellular Proteomics

Plasmacytoid Dendritic Cells Provide Protection Against Bacterial-Induced Colitis

Tania Rahman, Andrew S Brown, Elizabeth L Hartland, Ian R van Driel, Ka Yee Fung

Journal article  |  2019  |  Frontiers in Immunology

More than 18,000 effectors in the Legionella genus genome provide multiple, independent combinations for replication in human cells

Laura Gomez-Valero, Christophe Rusniok, Danielle Carson, Sonia Mondino, Ana Elena Perez-Cobas, Monica Rolando, Shivani Pasricha, Sandra Reuter, Jasmin Demirtas, Johannes Crumbach, Stephane Descorps-Declere, Elizabeth L Hartland, Sophie Jarraud, Gordon Dougan, Gunnar N Schroeder, Gad Frankel, Carmen Buchrieser

Journal article  |  2019  |  Proceedings of the National Academy of Sciences

The Mouse as a Model for Pulmonary Legionella Infection.

Garrett Z Ng, Anastasia Solomatina, Ian R van Driel, Elizabeth L Hartland

Book Chapter  |  2019  |  Methods in Molecular Biology

Infection of C57BL/6 mice with wild-type Legionella pneumophila typically results in very mild disease. However, in mice where the..

Biology and Pathogenesis of Legionella

Hayley J Newton, Elizabeth L Hartland, Matthias P Machner

Journal article  |  2018  |  Frontiers in Cellular and Infection Microbiology

Targeting of RNA Polymerase II by a nuclear Legionella pneumophila Dot/Icm effector SnpL

Ralf Schuelein, Hugh Spencer, Laura F Dagley, Peng Fei Li, Lin Luo, Jennifer L Stow, Gilu Abraham, Thomas Naderer, Laura Gomez-Valero, Carmen Buchrieser, Chihiro Sugimoto, Junya Yamagishi, Andrew I Webb, Shivani Pasricha, Elizabeth L Hartland

Journal article  |  2018  |  Cellular Microbiology

Citrobacter rodentium Infection Model for the Analysis of Bacterial Pathogenesis and Mucosal Immunology

Catherine L Kennedy, Elizabeth L Hartland

Journal article  |  2018  |  Methods in molecular biology (Clifton, N.J.)

Phasevarion-Regulated Virulence in the Emerging Pediatric Pathogen Kingella kingae

Yogitha N Srikhanta, Ka Yee Fung, Georgina L Pollock, Vicki Bennett-Wood, Benjamin P Howden, Elizabeth L Hartland

Journal article  |  2017  |  Infection and Immunity

Post-translational Mechanisms of Host Subversion by Bacterial Effectors

Nichollas E Scott, Elizabeth L Hartland

Journal article  |  2017  |  Trends in Molecular Medicine

Methylomic and phenotypic analysis of the ModH5 phasevarion of Helicobacter pylori

Yogitha N Srikhanta, Rebecca J Gorrell, Peter M Power, Kirill Tsyganov, Matthew Boitano, Tyson A Clark, Jonas Korlach, Elizabeth L Hartland, Michael P Jennings, Terry Kwok

Journal article  |  2017  |  Scientific Reports

The bacterial arginine glycosyltransferase effector NleB preferentially modifies Fas-associated death domain protein (FADD)

Nichollas E Scott, Cristina Giogha, Georgina L Pollock, Catherine L Kennedy, Andrew I Webb, Nicholas A Williamson, Jaclyn S Pearson, Elizabeth L Hartland

Journal article  |  2017  |  Journal of Biological Chemistry

The role of mass spectrometry analysis in bacterial effector characterization

Nichollas E Scott, Elizabeth L Hartland

Journal article  |  2017  |  Biochemical Journal

Distinct Roles of the Antiapoptotic Effectors NleB and NleF from Enteropathogenic Escherichia coli

Georgina L Pollock, Clare VL Oates, Cristina Giogha, Tania Wong Fok Lung, Sze Ying Ong, Jaclyn S Pearson, Elizabeth L Hartland

Journal article  |  2017  |  Infection and Immunity

EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation

Jaclyn S Pearson, Cristina Giogha, Sabrina Muhlen, Ueli Nachbur, Chi LL Pham, Ying Zhang, Joanne M Hildebrand, Clare V Oates, Tania Wong Fok Lung, Danielle Ingle, Laura F Dagley, Aleksandra Bankovacki, Emma J Petrie, Gunnar N Schroeder, Valerie F Crepin, Gad Frankel, Seth L Masters, James Vince, James M Murphy, Margaret Sunde, et al.

Journal article  |  2017  |  Nature Microbiology

The regulation of acute immune responses to the bacterial lung pathogen Legionella pneumophila

Andrew Stephen Brown, Chao Yang, Elizabeth Louise Hartland, Ian Richard van Driel

Journal article  |  2017  |  Journal of Leukocyte Biology

Legionella phosphoinositide tailoring A newly identified phosphoinositide kinase helps to generate phosphatidylinositol 4-phosphate (PtdIns4P) on the vacuolar membrane of the intracellular pathogen Legionella pneumophila. Sequential effector protein cooperation explains the unusual enrichment of PtdIns4P on the Legionella-containing vacuole

Elizabeth L Hartland

Journal article  |  2017  |  Nature Microbiology

The Type III Effector NleD from Enteropathogenic Escherichia coli Differentiates between Host Substrates p38 and JNK

Kristina Creuzburg, Cristina Giogha, Tania Wong Fok Lung, Nichollas E Scott, Sabrina Muehlen, Elizabeth L Hartland, Jaclyn S Pearson

Journal article  |  2017  |  Infection and Immunity

Identification of a Distinct Substrate-binding Domain in the Bacterial Cysteine Methyltransferase Effectors NleE and OspZ

Ying Zhang, Sabrina Muehlen, Clare V Oates, Jaclyn S Pearson, Elizabeth L Hartland

Journal article  |  2016  |  Journal of Biological Chemistry

Inhibitors for the bacterial ectonucleotidase Lp1NTPDase from Legionella pneumophila

Amelie Fiene, Younis Baqi, Enas M Malik, Patrice Newton, Wenjin Li, Sang-Yong Lee, Elizabeth L Hartland, Christa E Mueller

Journal article  |  2016  |  Bioorganic & Medicinal Chemistry

Cooperation between Monocyte-Derived Cells and Lymphoid Cells in the Acute Response to a Bacterial Lung Pathogen

Andrew S Brown, Chao Yang, Ka Yee Fung, Annabell Bachem, Dorothee Bourges, Sammy Bedoui, Elizabeth L Hartland, Ian R van Driel

Journal article  |  2016  |  PLOS Pathogens

Mutagenesis and Functional Analysis of the Bacterial Arginine Glycosyltransferase Effector NleB1 from Enteropathogenic Escherichia coli

Tania Wong Fok Lung, Cristina Giogha, Kristina Creuzburg, Sze Ying Ong, Georgina L Pollock, Ying Zhang, Ka Yee Fung, Jaclyn S Pearson, Elizabeth L Hartland

Journal article  |  2016  |  Infection and Immunity

Eliminating Legionella by inhibiting BCL-XL to induce macrophage apoptosis

Mary Speir, Kate E Lawlor, Stefan P Glaser, Gilu Abraham, Seong Chow, Adam Vogrin, Keith E Schulze, Ralf Schuelein, Lorraine A O'Reilly, Kylie Mason, Elizabeth L Hartland, Trevor Lithgow, Andreas Strasser, Guillaume Lessene, David CS Huang, James E Vince, Thomas Naderer

Journal article  |  2016  |  Nature Microbiology

Legionella pneumophila S1P-lyase targets host sphingolipid metabolism and restrains autophagy

Monica Rolando, Pedro Escoll, Tamara Nora, Joelle Botti, Valarie Boitez, Carmen Bedia, Craig Daniels, Gilu Abraham, Peter J Stogios, Tatiana Skarina, Charlotte Christophe, Delphine Dervins-Ravault, Christel Cazalet, Hubert Hilbi, Thusitha WT Rupasinghe, Dedreia Tull, Malcolm J McConville, Sze Ying Ong, Elizabeth L Hartland, Patrice Codogno, et al.

Journal article  |  2016  |  Proceedings of the National Academy of Sciences

Editorial overview: Host-microbe interactions: bacteria: Secretion systems, effectors, immunity and metabolism

Elizabeth L Hartland, Anthony R Richardson

Journal article  |  2016  |  Current Opinion in Microbiology

The Genetics of Enteropathogenic Escherichia coli Virulence

Jaclyn S Pearson, Cristina Giogha, Tania Wong Fok Lung, Elizabeth L Hartland

Journal article  |  2016  |  Annual Review of Genetics

Substrate recognition by the zinc metalloprotease effector NleC from enteropathogenic Escherichia coli

Cristina Giogha, Tania Wong Fok Lung, Sabrina Muehlen, Jaclyn S Pearson, Elizabeth L Hartland

Journal article  |  2015  |  Cellular Microbiology

Legionella pneumophila Effector LpdA Is a Palmitoylated Phospholipase D Virulence Factor

Gunnar N Schroeder, Philipp Aurass, Clare V Oates, Edward W Tate, Elizabeth L Hartland, Antje Flieger, Gad Frankel

Journal article  |  2015  |  Infection and Immunity

SseK3 Is a Salmonella Effector That Binds TRIM32 and Modulates the Host's NF-kappa B Signalling Activity

Zhe Yang, Amelia Soderholm, Tania Wong Fok Lung, Cristina Giogha, Michelle M Hill, Nathaniel F Brown, Elizabeth Hartland, Rohan D Teasdale

Journal article  |  2015  |  PLOS ONE

Soluble NSF attachment protein receptor molecular mimicry by a Legionella pneumophilaDot/Icm effector

Nathan P King, Patrice Newton, Ralf Schuelein, Darren L Brown, Marketa Petru, Vojtech Zarsky, Pavel Dolezal, Lin Luo, Andrea Bugarcic, Amanda C Stanley, Rachael Z Murray, Brett M Collins, Rohan D Teasdale, Elizabeth L Hartland, Jennifer L Stow

Journal article  |  2015  |  Cellular Microbiology

A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production

Ueli Nachbur, Che A Stafford, Aleksandra Bankovacki, Yifan Zhan, Lisa M Lindqvist, Berthe K Fiil, Yelena Khakham, Hyun-Ja Ko, Jarrod J Sandow, Hendrik Falk, Jessica K Holien, Diep Chau, Joanne Hildebrand, James E Vince, Phillip P Sharp, Andrew I Webb, Katherine A Jackman, Sabrina Muehlen, Catherine L Kennedy, Kym N Lowes, et al.

Journal article  |  2015  |  Nature Communications

BTB-ZF transcriptional regulator PLZF modifies chromatin to restrain inflammatory signaling programs

Anthony J Sadler, Fernando J Rossello, Liang Yu, James A Deane, Xiangliang Yuan, Die Wang, Aaron T Irving, Maria Kaparakis-Liaskos, Michael P Gantier, Hangjie Ying, Howard CH Yim, Elizabeth L Hartland, Amanda J Notini, Suzan de Boer, Stefan J White, Ashley Mansell, Jun-Ping Liu, D Neil Watkins, Steve Gerondakis, Bryan RG Williams, et al.

Journal article  |  2015  |  Proceedings of the National Academy of Sciences

Post-modern pathogens: surprising activities of translocated effectors from E-coil and Legionella

Jaclyn S Pearson, Ying Zhang, Hayley J Newton, Elizabeth L Hartland

Journal article  |  2015  |  Current Opinion in Microbiology

Fas regulates neutrophil lifespan during viral and bacterial infection

Joanne A O'Donnell, Catherine L Kennedy, Marc Pellegrini, Cameron J Nowell, Jian-Guo Zhang, Lorraine A O'Reilly, Louise Cengia, Stuart Dias, Seth L Masters, Elizabeth L Hartland, Andrew W Roberts, Motti Gerlic, Ben A Croker

Journal article  |  2015  |  Journal of Leukocyte Biology

Golgi-Located NTPDase1 of Leishmania major Is Required for Lipophosphoglycan Elongation and Normal Lesion Development whereas Secreted NTPDase2 Is Dispensable for Virulence

Fiona M Sansom, Julie E Ralton, M Fleur Sernee, Alice M Cohen, David J Hooker, Elizabeth L Hartland, Thomas Naderer, Malcolm J McConville

Journal article  |  2014  |  PLoS Neglected Tropical Diseases

The cell death response to enteropathogenic Escherichia coli infection

Tania Wong Fok Lung, Jaclyn S Pearson, Ralf Schuelein, Elizabeth L Hartland

Journal article  |  2014  |  Cellular Microbiology

The Escherichia coli effector EspJ blocks Src kinase activity via amidation and ADP ribosylation

Joanna C Young, Abigail Clements, Alexander E Lang, James A Garnett, Diana Munera, Ana Arbeloa, Jaclyn Pearson, Elizabeth L Hartland, Stephen J Matthews, Aurelie Mousnier, David J Barry, Michael Way, Andreas Schlosser, Klaus Aktories, Gad Frankel

Journal article  |  2014  |  Nature Communications

The Type III Secretion Effector NleF of Enteropathogenic Escherichia coli Activates NF-kappa B Early during Infection

Mitchell A Pallett, Cedric N Berger, Jaclyn S Pearson, Elizabeth L Hartland, Gad Frankel

Journal article  |  2014  |  Infection and Immunity

A Horizontally Acquired Transcription Factor Coordinates Salmonella Adaptations to Host Microenvironments

Nat F Brown, Lindsay D Rogers, Kristy L Sanderson, Joost W Gouw, Elizabeth L Hartland, Leonard J Foster

Journal article  |  2014  |  mBio

Multiple ecto-nucleoside triphosphate diphosphohydrolases facilitate intracellular replication of Legionella pneumophila

Patrice Riedmaier, Fiona M Sansom, Trifina Sofian, Travis Beddoe, Ralf Schuelein, Hayley J Newton, Elizabeth L Hartland

Journal article  |  2014  |  Biochemical Journal

Genetic Diversity and Virulence Potential of Shiga Toxin-Producing Escherichia coli O113:H21 Strains Isolated from Clinical, Environmental, and Food Sources

Peter CH Feng, Sabine Delannoy, David W Lacher, Luis Fernando dos Santos, Lothar Beutin, Patrick Fach, Marta Rivas, Elizabeth L Hartland, Adrienne W Paton, Beatriz EC Guth

Journal article  |  2014  |  Applied and Environmental Microbiology

The Inflammatory Response during Enterohemorrhagic Escherichia coli Infection.

Jaclyn S Pearson, Elizabeth L Hartland

Journal article  |  2014  |  Microbiology Spectrum

The inflammatory response is an integral part of host defense against enterohemorrhagic Escherichia coli (EHEC) infection and also..

A New Method To Determine In Vivo Interactomes Reveals Binding of the Legionella pneumophila Effector PieE to Multiple Rab GTPases

Aurelie Mousnier, Gunnar N Schroeder, Charlotte A Stoneham, Ernest C So, James A Garnett, Lu Yu, Steve J Matthews, Jyoti S Choudhary, Elizabeth L Hartland, Gad Frankel

Journal article  |  2014  |  MBIO

Rab8a interacts directly with PI3K gamma to modulate TLR4-driven PI3K and mTOR signalling

Lin Luo, Adam A Wall, Jeremy C Yeo, Nicholas D Condon, Suzanne J Norwood, Simone Schoenwaelder, Kaiwen W Chen, Shaun Jackson, Brendan J Jenkins, Elizabeth L Hartland, Kate Schroder, Brett M Collins, Matthew J Sweet, Jennifer L Stow

Journal article  |  2014  |  Nature Communications

A Screen of Coxiella burnetii Mutants Reveals Important Roles for Dot/Icm Effectors and Host Autophagy in Vacuole Biogenesis

Hayley J Newton, Lara J Kohler, Justin A McDonough, Morayma Temoche-Diaz, Emerson Crabill, Elizabeth L Hartland, Craig R Roy

Journal article  |  2014  |  PLoS Pathogens

Inhibition of death receptor signaling by bacterial gut pathogens

Cristina Giogha, Tania Wong Fok Lung, Jaclyn S Pearson, Elizabeth L Hartland

Journal article  |  2014  |  Cytokine & Growth Factor Reviews

Comparative analyses of Legionella species identifies genetic features of strains causing Legionnaires¿ disease

Laura Gomez-Valero, Christophe Rusniok, Monica Rolando, Mario Neou, Delphine Dervins-Ravault, Jasmin Demirtas, Zoe Rouy, Robert J Moore, Honglei Chen, Nicola K Petty, Sophie Jarraud, Jerome Etienne, Michael Steinert, Klaus Heuner, Simonetta Gribaldo, Claudine Médigue, Gernot Glöckner, Elizabeth L Hartland, Carmen Buchrieser

Journal article  |  2014  |  Genome Biology

CD8 subunit expression by plasmacytoid dendritic cells is variable, and does not define stable subsets

AS Brown, D Bourges, DK Ang, EL Hartland, IR van Driel

Journal article  |  2014  |  Mucosal Immunology

Mouse Models of Legionnaires' Disease

Andrew S Brown, Ian R van Driel, Elizabeth L Hartland

Journal article  |  2014  |  Current Topics in Microbiology and Immunology

Comparative analyses of Legionella species identifies genetic features of strains causing Legionnaires' disease

Laura Gomez-Valero, Christophe Rusniok, Monica Rolando, Mario Neou, Delphine Dervins-Ravault, Jasmin Demirtas, Zoe Rouy, Robert J Moore, Honglei Chen, Nicola K Petty, Sophie Jarraud, Jerome Etienne, Michael Steinert, Klaus Heuner, Simonetta Gribaldo, Claudine Medigue, Gernot Gloeckner, Elizabeth L Hartland, Carmen Buchrieser

Journal article  |  2014  |  Genome Biology

A surprising sweetener from enteropathogenic Escherichia coli

Jaclyn S Pearson, Elizabeth L Hartland

Journal article  |  2014  |  Gut Microbes

LtpD Is a Novel Legionella pneumophila Effector That Binds Phosphatidylinositol 3-Phosphate and Inositol Monophosphatase IMPA1

Clare R Harding, Corinna Mattheis, Aurelie Mousnier, Clare V Oates, Elizabeth L Hartland, Gad Frankel, Gunnar N Schroeder

Journal article  |  2013  |  Infection and Immunity

Disarming Bacterial Virulence through Chemical Inhibition of the DNA Binding Domain of an AraC-like Transcriptional Activator Protein

Ji Yang, Dianna M Hocking, Catherine Cheng, Con Dogovski, Matthew A Perugini, Jessica K Holien, Michael W Parker, Elizabeth L Hartland, Marija Tauschek, Roy M Robins-Browne

Journal article  |  2013  |  Journal of Biological Chemistry

A type III effector antagonizes death receptor signalling during bacterial gut infection

Jaclyn S Pearson, Cristina Giogha, Sze Ying Ong, Catherine L Kennedy, Michelle Kelly, Keith S Robinson, Tania Wong Fok Lung, Ashley Mansell, Patrice Riedmaier, Clare VL Oates, Ali Zaid, Sabrina Muehlen, Valerie F Crepin, Olivier Marches, Ching-Seng Ang, Nicholas A Williamson, Lorraine A O'Reilly, Aleksandra Bankovacki, Ueli Nachbur, Giuseppe Infusini, et al.

Journal article  |  2013  |  Nature

Masters, marionettes and modulators: intersection of pathogen virulence factors and mammalian death receptor signaling

John Silke, Elizabeth L Hartland

Journal article  |  2013  |  Current Opinion in Immunology

The Dot/Icm Effector SdhA Is Necessary for Virulence of Legionella pneumophila in Galleria mellonella and A/J Mice

Clare R Harding, Charlotte A Stoneham, Ralf Schuelein, Hayley Newton, Clare V Oates, Elizabeth L Hartland, Gunnar N Schroeder, Gad Frankel

Journal article  |  2013  |  Infection and Immunity

Characterization of the ospZ Promoter in Shigella flexneri and Its Regulation by VirB and H-NS

David W Basta, Krystle L Pew, Joy A Immak, Hiromichi S Park, Michael A Picker, Amanda F Wigley, Christopher T Hensley, Jaclyn S Pearson, Elizabeth L Hartland, Helen J Wing

Journal article  |  2013  |  Journal of Bacteriology

Enteropathogenic and enterohemorrhagic E. coli: ecology, pathogenesis, and evolution

Elizabeth L Hartland, John M Leong

Journal article  |  2013  |  Frontiers in Cellular and Infection Microbiology

Disarming bacterial virulence through chemical inhibition of the DNA-binding domain of an AraC-like transcriptional activator protein.

J Yang, DM Hocking, CY Cheng, C Dogovski, MA Perugini, JK Holien, MW Parker, EL Hartland, M Tauschek, RM Robins-Browne

Journal article  |  2013  |  Journal of Biological Chemistry

Subcellular localization of legionella Dot/Icm effectors.

Adam J Vogrin, Aurelie Mousnier, Gad Frankel, Elizabeth L Hartland

Journal article  |  2013  |  Methods in Molecular Biology

The translocation of effector proteins by the Dot/Icm type IV secretion system is central to the ability of Legionella pneumophila..

A method for quantifying pulmonary Legionella pneumophila infection in mouse lungs by flow cytometry.

Desmond Koon Yong Ang, Sze Ying Ong, Andrew Stephen Brown, Elizabeth Louise Hartland, Ian Richard van Driel

Journal article  |  2012  |  BMC Research Notes

BACKGROUND: Pulmonary load of Legionella pneumophila in mice is normally determined by counting serial dilutions of bacterial colo..

Discovery of an archetypal protein transport system in bacterial outer membranes

Joel Selkrig, Khedidja Mosbahi, Chaille T Webb, Matthew J Belousoff, Andrew J Perry, Timothy J Wells, Faye Morris, Denisse L Leyton, Makrina Totsika, Phan Minh-Duy, Nermin Celik, Michelle Kelly, Clare Oates, Elizabeth L Hartland, Roy M Robins-Browne, Sri Harsha Ramarathinam, Anthony W Purcell, Mark A Schembri, Richard A Strugnell, Ian R Henderson, et al.

Journal article  |  2012  |  Nature Structural and Molecular Biology

Legionella pneumophila Secretes a Mitochondrial Carrier Protein during Infection

Pavel Dolezal, Margareta Aili, Janette Tong, Jhih-Hang Jiang, Carlo M Marobbio, Sau Fung Lee, Ralf Schuelein, Simon Belluzzo, Eva Binova, Aurelie Mousnier, Gad Frankel, Giulia Giannuzzi, Ferdinando Palmieri, Kipros Gabriel, Thomas Naderer, Elizabeth L Hartland, Trevor Lithgow

Journal article  |  2012  |  PLoS Pathogens

EspG of enteropathogenic and enterohemorrhagic E. coli binds the Golgi matrix protein GM130 and disrupts the Golgi structure and function

Abigail Clements, Katherine Smollett, Sau Fung Lee, Elizabeth L Hartland, Martin Lowe, Gad Frankel

Journal article  |  2011  |  Cellular Microbiology

Sculpting the immune response to infection.

Paul J Hertzog, Ashley Mansell, Ian R van Driel, Elizabeth L Hartland

Journal article  |  2011  |  Nature Immunology

Enteropathogenic and enterohaemorrhagic Escherichia coli: even more subversive elements

Alexander RC Wong, Jaclyn S Pearson, Michael D Bright, Diana Munera, Keith S Robinson, Sau Fung Lee, Gad Frankel, Elizabeth L Hartland

Journal article  |  2011  |  Molecular Microbiology

A type III effector protease NleC from enteropathogenic Escherichia coli targets NF-kappa B for degradation

Jaclyn S Pearson, Patrice Riedmaier, Olivier Marches, Gad Frankel, Elizabeth L Hartland

Journal article  |  2011  |  Molecular Microbiology

Enteropathogenic and Enterohemorrhagic Escherichia coli Type III Secretion Effector EspV Induces Radical Morphological Changes in Eukaryotic Cells

Ana Arbeloa, Clare V Oates, Oliver Marches, Elizabeth L Hartland, Gad Frankel

Journal article  |  2011  |  Infection and Immunity

Immune control of Legionella infection: an in vivo perspective

Ralf Schuelein, Desmond KY Ang, Ian R van Driel, Elizabeth L Hartland

Journal article  |  2011  |  Frontiers in Microbiology

Binding to Na /H exchanger regulatory factor 2 (NHERF2) affects trafficking and function of the enteropathogenic Escherichia coli type III secretion system effectors Map, EspI and NleH

Eric Martinez, Gunnar N Schroeder, Cedric N Berger, Sau Fung Lee, Keith S Robinson, Luminita Badea, Nandi Simpson, Randy A Hall, Elizabeth L Hartland, Valerie F Crepin, Gad Frankel

Journal article  |  2010  |  Cellular Microbiology

Legionella pneumophila Strain 130b Possesses a Unique Combination of Type IV Secretion Systems and Novel Dot/Icm Secretion System Effector Proteins

Gunnar N Schroeder, Nicola K Petty, Aurelie Mousnier, Clare R Harding, Adam J Vogrin, Bryan Wee, Norman K Fry, Timothy G Harrison, Hayley J Newton, Nicholas R Thomson, Scott A Beatson, Gordon Dougan, Elizabeth L Hartland, Gad Frankel

Journal article  |  2010  |  Journal of Bacteriology

The Legionella pneumophila F-box protein Lpp2082 (AnkB) modulates ubiquitination of the host protein parvin B and promotes intracellular replication

M Lomma, D Dervins-Ravault, M Rolando, T Nora, HJ Newton, FM Sansom, T Sahr, L Gomez-Valero, M Jules, EL Hartland, C Buchrieser

Journal article  |  2010  |  Cellular Microbiology

Two Novel Point Mutations in Clinical Staphylococcus aureus Reduce Linezolid Susceptibility and Switch on the Stringent Response to Promote Persistent Infection

Wei Gao, Kyra Chua, John K Davies, Hayley J Newton, Torsten Seemann, Paul F Harrison, Natasha E Holmes, Hyun-Woo Rhee, Jong-In Hong, Elizabeth L Hartland, Timothy P Stinear, Benjamin P Howden

Journal article  |  2010  |  PLoS Pathogens

Cutting Edge: Pulmonary Legionella pneumophila Is Controlled by Plasmacytoid Dendritic Cells but Not Type I IFN

Desmond KY Ang, Clare VL Oates, Ralf Schuelein, Michelle Kel Ly, Fiona M Sansom, Dorothee Bourges, Louis Boon, Paul J Hertzog, Elizabeth L Hartland, Ian R van Driel

Journal article  |  2010  |  Journal of Immunology

Virulence regulation in Citrobacter rodentium: the art of timing

Ji Yang, Marija Tauschek, Emily Hart, Elizabeth L Hartland, Roy M Robins-Browne

Journal article  |  2010  |  Microbial Biotechnology

The innate immune molecule, NOD1, regulates direct killing of Helicobacter pylori by antimicrobial peptides

Alexandra Grubman, Maria Kaparakis, Jerome Viala, Cody Allison, Luminita Badea, Abdulgader Karrar, Ivo G Boneca, Lionel Le Bourhis, Shane Reeve, Ian A Smith, Elizabeth L Hartland, Dana J Philpott, Richard L Ferrero

Journal article  |  2010  |  Cellular Microbiology

The Type III Effectors NleE and NleB from Enteropathogenic E. coli and OspZ from Shigella Block Nuclear Translocation of NF-kappa B p65

Hayley J Newton, Jaclyn S Pearson, Luminita Badea, Michelle Kelly, Mark Lucas, Gavan Holloway, Kylie M Wagstaff, Michelle A Dunstone, Joan Sloan, James C Whisstock, James B Kaper, Roy M Robins-Browne, David A Jans, Gad Frankel, Alan D Phillips, Barbara S Coulson, Elizabeth L Hartland

Journal article  |  2010  |  PLoS Pathogens

Update on Legionnaires' disease: pathogenesis, epidemiology, detection and control

Hubert Hilbi, Sophie Jarraud, Elizabeth Hartland, Carmen Buchrieser

Journal article  |  2010  |  Molecular Microbiology

Molecular Pathogenesis of Infections Caused by Legionella pneumophila

Hayley J Newton, Desmond KY Ang, Ian R van Driel, Elizabeth L Hartland

Journal article  |  2010  |  Clinical Microbiology Reviews

Crystal Structure of a Legionella pneumophila Ecto-Triphosphate Diphosphohydrolase, A Structural and Functional Homolog of the Eukaryotic NTPDases

Julian P Vivian, Patrice Riedmaier, Honghua Ge, Jerome Le Nours, Fiona M Sansom, Matthew CJ Wilce, Emma Byres, Manisha Dias, Jason W Schmidberger, Peter J Cowan, Anthony JF d'Apice, Elizabeth L Hartland, Jamie Rossjohn, Travis Beddoe

Journal article  |  2010  |  Structure

Analysis of the Legionella longbeachae Genome and Transcriptome Uncovers Unique Strategies to Cause Legionnaires' Disease

Christel Cazalet, Laura Gomez-Valero, Christophe Rusniok, Mariella Lomma, Delphine Dervins-Ravault, Hayley J Newton, Fiona M Sansom, Sophie Jarraud, Nora Zidane, Laurence Ma, Christiane Bouchier, Jerome Etienne, Elizabeth L Hartland, Carmen Buchrieser

Journal article  |  2010  |  PLoS Genetics

Molecular detection of Legionella: moving on from mip

Stacey FY Yong, Shin Hwa Tan, Joanne Wee, Jing Jhi Tee, Fiona M Sansom, Hayley J Newton, Elizabeth L Hartland

Journal article  |  2010  |  Frontiers in Microbiology

Interactions of 40LoVe within the ribonucleoprotein complex that forms on the localization element of Xenopus Vg1 mRNA

Todd T Kroll, Lara B Swenson, Emilia I Hartland, Donald D Snedden, Holly V Goodson, Paul W Huber

Journal article  |  2009  |  Mechanisms of Development

Rabbit-specific fimbriae, Ral, alter the patterns of in vitro adherence and intestinal colonisation of rabbits by human-specific enteropathogenic E. coli

Emily Hart, Marija Tauschek, Vicki Bennett-Wood, Elizabeth L Hartland, Roy A Robins-Browne

Journal article  |  2009  |  Microbes and Infection

Characterisation of atypical enteropathogenic E. coli strains of clinical origin

Sharon M Tennant, Marija Tauschek, Kristy Azzopardi, Andrea Bigham, Vicki Bennett-Wood, Elizabeth L Hartland, Weihong Qi, Thomas S Whittam, Roy M Robins-Browne

Journal article  |  2009  |  BMC Microbiology

Experimental Legionella longbeachae infection in intratracheally inoculated mice

Ivana Gobin, Milorad Susa, Gabrijela Begic, Elizabeth L Hartland, Miljenko Doric

Journal article  |  2009  |  Journal of Medical Microbiology

Contribution of the pst-phoU Operon to Cell Adherence by Atypical Enteropathogenic Escherichia coli and Virulence of Citrobacter rodentium

Catherine Cheng, Sharon M Tennant, Kristy I Azzopardi, Vicki Bennett-Wood, Elizabeth L Hartland, Roy M Robins-Browne, Marija Tauschek

Journal article  |  2009  |  Infection and Immunity

Shiga Toxin-producing Escherichia coli Strains Negative for Locus of Enterocyte Effacement

Hayley J Newton, Joan Sloan, Dieter M Bulach, Torsten Seemann, Cody C Allison, Marija Tauschek, Roy M Robins-Browne, James C Paton, Thomas S Whittam, Adrienne W Paton, Elizabeth L Hartland

Journal article  |  2009  |  Emerging Infectious Diseases

Secretion of flagellin by the LEE-encoded type III secretion system of enteropathogenic Escherichia coli

Luminita Badea, Scott A Beatson, Maria Kaparakis, Richard L Ferrero, Elizabeth L Hartland

Journal article  |  2009  |  BMC Microbiology

Infections caused by nonpneumophila species of Legionella

Ivana Gobin, Peter R Newton, Elizabeth L Hartland, Hayley J Newton

Journal article  |  2009  |  Reviews in Medical Microbiology

Possible Effects of Microbial Ecto-Nucleoside Triphosphate Diphosphohydrolases on Host-Pathogen Interactions

Fiona M Sansom, Simon C Robson, Elizabeth L Hartland

Journal article  |  2008  |  Microbiology and Molecular Biology Reviews

The Major Surface-Associated Saccharides of Klebsiella pneumoniae Contribute to Host Cell Association

Abigail Clements, Fabien Gaboriaud, Jerome FL Duval, Jacinta L Farn, Adam W Jenney, Trevor Lithgow, Odilia LC Wijburg, Elizabeth L Hartland, Richard A Strugnell

Journal article  |  2008  |  PLoS One

RegA, an AraC-Like Protein, Is a Global Transcriptional Regulator That Controls Virulence Gene Expression in Citrobacter rodentium

Emily Hart, Ji Yang, Marija Tauschek, Michelle Kelly, Matthew J Wakefield, Gad Frankel, Elizabeth L Hartland, Roy M Robins-Browne

Journal article  |  2008  |  Infection and Immunity

Targeting subcapsular antigens for prevention of Klebsiella pneumoniae infections

Abigail Clements, Adam W Jenney, Jacinta L Farn, Lorena E Brown, Georgia Deliyannis, Elizabeth L Hartland, Martin J Pearse, Margaret B Maloney, Steven L Wesselingh, Odilia L Wijburg, Richard A Strugnell

Journal article  |  2008  |  Vaccine

Bacterial protein secretion and trafficking down under. Annual Scientific Meeting of the Australian Society for Microbiology, 6-10 July 2008, Melbourne Convention Center, Victoria, Australia.

Elizabeth L Hartland, Trevor Lithgow

Journal article  |  2008  |  Future Microbiology

Significant role for ladC in initiation of Legionella pneumophila infection

Hayley J Newton, Fiona M Sansom, Jenny Dao, Christel Cazalet, Holger Bruggemann, Christiane Albert-Weissenberger, Carmen Buchrieser, Nicholas P Cianciotto, Elizabeth L Hartland

Journal article  |  2008  |  Infection and Immunity

Enzymatic properties of an ecto-nucleoside triphosphate diphosphohydrolase from Legionella pneumophila - Substrate specificity and requirement for virulence

Fiona M Sansom, Patrice Riedmaier, Hayley J Newton, Michelle A Dunstone, Christa E Mueller, Holger Stephan, Emma Byres, Travis Beddoe, Jamie Rossjohn, Peter J Cowan, Anthony JF d'Apice, Simon C Robson, Elizabeth L Hartland

Journal article  |  2008  |  Journal of Biological Chemistry

Bicarbonate-mediated transcriptional activation of divergent operons by the virulence regulatory protein, RegA, from Citrobacter rodentium

Ji Yang, Emily Hart, Marija Tauschek, G Dean Price, Elizabeth L Hartland, Richard A Strugnell, Roy M Robins-Browne

Journal article  |  2008  |  Molecular Microbiology

A C-terminal class IPDZ binding motif of EspI/NleA modulates the virulence of attaching and effacing Escherichia coli and Citrobacter rodentium

Sau Fung Lee, Michelle Kelly, Adrian McAlister, Shelley N Luck, Erin L Garcia, Randy A Hall, Roy M Robins-Browne, Gad Frankel, Elizabeth L Hartland

Journal article  |  2008  |  Cellular Microbiology

Influence of gastric acid on susceptibility to infection with ingested bacterial pathogens

Sharon M Tennant, Elizabeth L Hartland, Tongted Phumoonna, Dena Lyras, Julian I Rood, Roy M Robins-Browne, Ian R van Driel

Journal article  |  2008  |  Infection and Immunity

The NleE/OspZ family of effector proteins is required for polymorphonuclear transepithelial migration, a characteristic shared by enteropathogenic Escherichia coli and Shigella flexneri infections

Daniel V Zurawski, Karen L Mumy, Luminita Badea, Julia A Prentice, Elizabeth L Hartland, Beth A McCormick, Anthony T Maurelli

Journal article  |  2008  |  Infection and Immunity

Sell repeat protein LpnE is a Legionella pneumophila virulence determinant that influences vacuolar trafficking

Hayley J Newton, Fiona M Sansom, Jenny Dao, Adrian D McAlister, Joan Sloan, Nicholas P Cianciotto, Elizabeth L Hartland

Journal article  |  2007  |  Infection and immunity

Sel1 repeat protein LpnE is a Legionella pneumophila virulence determinant that influences vacuolar trafficking

HJ Newton, FM Sansom, J Dao, AD McAlister, J Sloan, NP Cianciotto, EL Hartland

Journal article  |  2007  |  Infection and Immunity

A common fold mediates vertebrate defense and bacterial attack

Carlos J Rosado, Ashley M Buckle, Ruby HP Law, Rebecca E Butcher, Wan-Ting Kan, Catherina H Bird, Kheng Ung, Kylie A Browne, Katherine Baran, Tanya A Bashtannyk-Puhalovich, Noel G Faux, Wilson Wong, Corrine J Porter, Robert N Pike, Andrew M Ellisdon, Mary C Pearce, Stephen P Bottomley, Jonas Emsley, A Ian Smith, Jamie Rossjohn, et al.

Journal article  |  2007  |  Science

The bacterial virulence factor NleA inhibits cellular protein secretion by disrupting mammalian COPII function

Jinoh Kim, Ajitha Thanabalasuriar, Tessa Chaworth-Musters, J Chris Fromme, Elizabeth A Frey, Paula I Lario, Pavel Metalnikov, Keyrillos Rizg, Nikhil A Thomas, Sau Fung Lee, Elizabeth L Hartland, Philip R Hardwidge, Tony Pawson, Natalie C Strynadka, B Brett Finlay, Randy Schekman, Samantha Gruenheid

Journal article  |  2007  |  Cell Host & Microbe

Contribution of a novel gene, rpeA, encoding a putative autotransporter adhesin to intestinal colonization by rabbit-specific enteropathogenic Eschetichia coli

Denisse L Leyton, Louise M Adams, Michelle Kelly, Joan Sloan, Marija Tauschek, Roy M Robins-Browne, Elizabeth L Hartland

Journal article  |  2007  |  Infection and Immunity

A bacterial ecto-triphosphate diphosphohydrolase similar to human CD39 is essential for intracellular multiplication of Legionella pneumophila

Fiona M Sansom, Hayley J Newton, Sandra Crikis, Nicholas P Cianciotto, Peter J Cowan, Anthony JF d'Apice, Elizabeth L Hartland

Journal article  |  2007  |  Cellular Microbiology

Secondary acylation of Klebsiella pneumoniae lipopolysaccharide contributes to sensitivity to antibacterial peptides

Abigail Clements, Dedreia Tull, Adam W Jenney, Jacinta L Farn, Sang-Hyun Kim, Russell E Bishop, Joseph B McPhee, Robert EW Hancock, Elizabeth L Hartland, Martin J Pearse, Odilia LC Wijburg, David C Jackson, Malcolm J McConville, Richard A Strugnell

Journal article  |  2007  |  Journal of Biological Chemistry

Contribution of FliC to epithelial cell invasion by enterohemorrhagic Escherichia coli O113 : H21

Shelley N Luck, Luminita Badea, Vicki Bennett-Wood, Roy Robins-Browne, Elizabeth L Hartland

Journal article  |  2006  |  Infection and Immunity

Essential role of the type III secretion system effector NleB in colonization of mice by Citrobacter rodentium

M Kelly, E Hart, R Mundy, O Marches, S Wiles, L Badea, S Luck, M Tauschek, G Frankel, RM Robins-Browne, EL Hartland

Journal article  |  2006  |  Infection and Immunity

Identification of Legionella pneumophila-specific genes by genomic subtractive hybridization with Legionella micdadei and identification of lpnE, a gene required for efficient host cell entry

HJ Newton, FM Sansom, V Bennett-Wood, EL Hartland

Journal article  |  2006  |  Infection and Immunity

Role of Legionella pneumophila-specific genes in pathogenesis

Hayley J Newton, Fiona M Sansom, Vicki Bennett-Wood, Elizabeth L Hartland

Conference Proceedings  |  2006  |  LEGIONELLA: STATE OF THE ART 30 YEARS AFTER ITS RECOGNITION

Eukaryotic-like proteins of Legionella pneumophila as potential virulence factors

Fiona M Sansom, Hayley J Newton, Elizabeth L Hartland

Conference Proceedings  |  2006  |  LEGIONELLA: STATE OF THE ART 30 YEARS AFTER ITS RECOGNITION

Characterization of two non-locus of enterocyte effacement-encoded type III-translocated effectors, NleC and NleD, in attaching and effacing pathogens

O Marches, S Wiles, F Dziva, RM La Ragione, S Schuller, A Best, AD Phillips, EL Hartland, MJ Woodward, MP Stevens, G Frankel

Journal article  |  2005  |  Infection and Immunity

Erratum: The coiled-coil domain of EspA is essential for the assembly of the type III secretion translocon on the surface of enteropathogenic Escherichia coli (Journal of Biological Chemistry (1999) 274 (35969-35974))

RM Delahay, S Knutton, RK Shaw, EL Hartland, MJ Pallen, G Frankel

Journal article  |  2005  |  Journal of Biological Chemistry

Invasion of epithelial cells by locus of enterocyte effacement-negative enterohemorrhagic Escherichia coli

SN Luck, V Bennett-Wood, R Poon, RM Robins-Browne, EL Hartland

Journal article  |  2005  |  Infection and Immunity

Tissue tropism in intestinal colonization

E HARTLAND, RM ROBINS-BROWNE, D PHILIPS, G FRANKEL

Book Chapter  |  2005

Contribution of long polar fimbriae to the virulence of rabbit-specific enteropathogenic Escherichia coli

HJ Newton, J Sloan, V Bennett-Wood, LM Adams, RM Robins-Browne, EL Hartland

Journal article  |  2004  |  Infection and Immunity

Prevalence of the lpf(O113) gene cluster among Escherichia coli O157 isolates from different sources

J Osek, M Weiner, EL Hartland

Journal article  |  2003  |  Veterinary Microbiology

Contribution of Efa1/LifA to the adherence of enteropathogenic Escherichia coli to epithelial cells

L Badea, S Doughty, L Nicholls, J Sloan, RM Robins-Browne, EL Hartland

Journal article  |  2003  |  Microbial Pathogenesis

Yersinia Species

RM ROBINS-BROWNE, E HARTLAND

Book Chapter  |  2003

Intimin type influences the site of human intestinal mucosa colonisation by enterohaemorrhagic Escherichia coli O157 : H7

RJ Fitzhenry, DJ Pickard, EL Hartland, S Reece, G Dougan, AD Phillips, G Frankel

Journal article  |  2002  |  Gut

Coiled-coil domain of enteropathogenic Escherichia coli type III secreted protein EspD is involved in EspA filament-mediated cell attachment and hemolysis

SJ Daniell, RM Delahay, RK Shaw, EL Hartland, MJ Pallen, F Booy, F Ebel, S Knutton, G Frankel

Journal article  |  2001  |  Infection and Immunity

Immune response to infection with Mycobacterium ulcerans

TM Gooding, PDR Johnson, DE Campbell, JA Hayman, EL Hartland, AS Kemp, RM Robins-Browne

Journal article  |  2001  |  Infection and Immunity

Expression of intimin gamma from enterohemorrhagic Escherichia coli in Citrobacter rodentium

EL Hartland, V Huter, LM Higgins, NS Goncalves, G Dougan, AD Phillips, TT MacDonald, G Frankel

Journal article  |  2000  |  Infection and Immunity

The type III protein translocation system of enteropathogenic Escherichia coli involves EspA-EspB protein interactions

EL Hartland, SJ Daniell, RM Delahay, BC Neves, T Wallis, RK Shaw, C Hale, S Knutton, G Frankel

Journal article  |  2000  |  Molecular Microbiology

Human colostrum and serum contain antibodies reactive to the intimin-binding region of the enteropathogenic Escherichia coli translocated intimin receptor

MI Sanches, R Keller, EL Hartland, DMM Figueiredo, M Batchelor, MB Martinez, G Dougan, MMS Careiro-Sampaio, G Frankel, LR Trabulsi

Journal article  |  2000  |  Journal of Pediatric Gastroenterology and Nutrition

Antibody response of patients infected with verocytotoxin-producing Escherichia coli to protein antigens encoded on the LEE locus

C Jenkins, H Chart, HR Smith, EL Hartland, M Batchelor, RM Delahay, G Dougan, G Frankel

Journal article  |  2000  |  Journal of General Virology

The coiled-coil domain of EspA is essential for the assembly of the type III secretion translocon on the surface of enteropathogenic Escherichia coli

RM Delahay, S Knutton, RK Shaw, EL Hartland, MJ Pallen, G Frankel

Journal article  |  1999  |  Journal of Biological Chemistry

Binding of intimin from enteropathogenic Escherichia coli to Tir and to host cells

EL Hartland, M Batchelor, RM Delahay, C Hale, S Matthews, G Dougan, S Knutton, I Connerton, G Frankel

Journal article  |  1999  |  Molecular Microbiology

Multiple leiomyosarcomas of both donor and recipient origin arising in a heart-lung transplant patient

CR Somers, AA Tesoriero, E Hartland, CF Robertson, PJ Robinson, CW Chow

Journal article  |  1998  |  The American Journal of Surgical Pathology

Infections with enteropathogenic Yersinia species: paradigms of bacterial pathogenesis

EL Hartland, RM Robins-Browne

Journal article  |  1998  |  Reviews in Medical Microbiology

Examination of Serpulina pilosicoli for attachment and invasion determinants of enterobacteria

EL Hartland, ASJ Mikosza, RM Robins-Browne, DJ Hampson

Journal article  |  1998  |  FEMS Microbiology Letters

In vitro association between the virulence proteins, YopD and YopE, of Yersinia enterocolitica

EL Hartland, RM Robins-Browne

Journal article  |  1998  |  FEMS Microbiology Letters

Contribution of YopB to virulence of Yersinia enterocolitica

EL Hartland, AM Bordun, RM RobinsBrowne

Journal article  |  1996  |  Infection and Immunity

Differential secretion of interleukin-8 by human epithelial cell lines upon entry of virulent or nonvirulent Yersinia enterocolitica

R Schulte, P Wattiau, EL Hartland, RM RobinsBrowne, GR Cornelis

Journal article  |  1996  |  Infection and Immunity

ROLE OF YOPH IN THE SUPPRESSION OF TYROSINE PHOSPHORYLATION AND RESPIRATORY BURST ACTIVITY IN MURINE MACROPHAGES INFECTED WITH YERSINIA-ENTEROCOLITICA

SP GREEN, EL HARTLAND, RM ROBINSBROWNE, WA PHILLIPS

Journal article  |  1995  |  Journal of Leukocyte Biology

Role of YopD in the virulence of Yersinia enterocolitica

EL Hartland, SP Green, WA Phillips, RM RobinsBrowne

Conference Proceedings  |  1995  |  Contributions to microbiology and immunology

The urease complex gene of Yersinia enterocolitica and its role in virulence

TF deKoningWard, AC Ward, EL Hartland, M RobinsBrowne

Journal article  |  1995  |  Contributions to microbiology and immunology

ESSENTIAL ROLE OF YOPD IN INHIBITION OF THE RESPIRATORY BURST OF MACROPHAGES BY YERSINIA-ENTEROCOLITICA

EL HARTLAND, SP GREEN, WA PHILLIPS, RM ROBINSBROWNE

Journal article  |  1994  |  Infection and Immunity