Scott Mueller

Sphingosine 1-phosphate receptor 5 (S1PR5) regulates the peripheral retention of tissue-resident lymphocytes

Maximilien Evrard, Erica Wynne-Jones, Changwei Peng, Yu Kato, Susan N Christo, Raissa Fonseca, Simone L Park, Thomas N Burn, Maleika Osman, Sapna Devi, Jerold Chun, Scott N Mueller, George Kannourakis, Stuart P Berzins, Daniel G Pellicci, William R Heath, Stephen C Jameson, Laura K Mackay

Journal article  |  2022  |  JOURNAL OF EXPERIMENTAL MEDICINE

Tissue-resident memory T (TRM) cells provide long-lasting immune protection. One of the key events controlling TRM cell developmen..

Moving beyond velocity: Opportunities and challenges to quantify immune cell behavior.

Dominik Schienstock, Scott N Mueller

Journal article  |  2021  |  Immunol Rev

The analysis of cellular behavior using intravital multi-photon microscopy has contributed substantially to our understanding of t..

MHC Class II Ubiquitination Regulates Dendritic Cell Function and Immunity.

Kayla R Wilson, Devi Jenika, Annabelle B Blum, Christophe Macri, Bangyan Xu, Haiyin Liu, Patrick Schriek, Dominik Schienstock, Lauren Francis, F Victor Makota, Satoshi Ishido, Scott N Mueller, Mireille H Lahoud, Irina Caminschi, Laura E Edgington-Mitchell, Jose A Villadangos, Justine D Mintern

Journal article  |  2021  |  J Immunol

MHC class II (MHC II) Ag presentation by dendritic cells (DCs) is critical for CD4+ T cell immunity. Cell surface levels of MHC II..

Neuroimmune interactions at the crossroads of health and disease

Scott N Mueller, Erica K Sloan

Journal article  |  2021  |  IMMUNOLOGY AND CELL BIOLOGY

Low-dose IL-2 therapy invigorates CD8( ) T cells for viral control in systemic lupus erythematosus with a potential risk of deteriorating immunopathology

Pengcheng Zhou, Jiali Chen, Jing He, Ting Zheng, Joseph Yunis, Victor Makota, Yannick O Alexandre, Fang Gong, Xia Zhang, Wuxiang Xie, Yuhui Li, Miao Shao, Yanshan Zhu, Jane E Sinclair, Miao Miao, Yaping Chen, Kirsty R Short, Scott N Mueller, Xiaolin Sun, Di Yu, et al.

Journal article  |  2021  |  PLOS PATHOGENS

Autoimmune diseases are often treated by glucocorticoids and immunosuppressive drugs that could increase the risk for infection, w..

CD8 and CD4 T Cells Infiltrate into the Brain during Plasmodium berghei ANKA Infection and Form Long-Term Resident Memory.

Nazanin Ghazanfari, Julia L Gregory, Sapna Devi, Daniel Fernandez-Ruiz, Lynette Beattie, Scott N Mueller, William R Heath

Journal article  |  2021  |  J Immunol

In the Plasmodium berghei ANKA mouse model of malaria, accumulation of CD8+ T cells and infected RBCs in the brain promotes the de..

Discrete tissue microenvironments instruct diversity in resident memory T cell function and plasticity

Susan N Christo, Maximilien Evrard, Simone L Park, Luke C Gandolfo, Thomas N Burn, Raissa Fonseca, Dane M Newman, Yannick O Alexandre, Nicholas Collins, Natasha M Zamudio, Fernando Souza-Fonseca-Guimaraes, Daniel G Pellicci, David Chisanga, Wei Shi, Laurent Bartholin, Gabrielle T Belz, Nicholas D Huntington, Andrew Lucas, Michaela Lucas, Scott N Mueller, et al.

Journal article  |  2021  |  NATURE IMMUNOLOGY

Tissue-resident memory T (TRM) cells are non-recirculating cells that exist throughout the body. Although TRM cells in various org..

Adrenergic regulation of the vasculature impairs leukocyte interstitial migration and suppresses immune responses

Sapna Devi, Yannick O Alexandre, Joon Keit Loi, Ryan Gillis, Nazanin Ghazanfari, Sarah J Creed, Lauren E Holz, David Shackleford, Laura K Mackay, William R Heath, Erica K Sloan, Scott N Mueller

Journal article  |  2021  |  IMMUNITY

The sympathetic nervous system (SNS) controls various physiological functions via the neurotransmitter noradrenaline. Activation o..

Understanding T cell phenotype for the design of effective chimeric antigen receptor T cell therapies.

Daniela Gm Tantalo, Amanda J Oliver, Bianca von Scheidt, Aaron J Harrison, Scott N Mueller, Michael H Kershaw, Clare Y Slaney

Journal article  |  2021  |  J Immunother Cancer

Rapid advances in immunotherapy have identified adoptive cell transfer as one of the most promising approaches for the treatment o..

Scavenging of soluble and immobilized CCL21 by ACKR4 regulates peripheral dendritic cell emigration

Cameron R Bastow, Mark D Bunting, Ervin E Kara, Duncan R McKenzie, Adriana Caon, Sapna Devi, Lynn Tolley, Scott N Mueller, Ian H Frazer, Natasha Harvey, Mark R Condina, Clifford Young, Peter Hoffmann, Shaun R McColl, Iain Comerford

Journal article  |  2021  |  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Leukocyte homing driven by the chemokine CCL21 is pivotal for adaptive immunity because it controls dendritic cell (DC) and T cell..