Steve Simpson-Yap

COVID-19 in people with multiple sclerosis: A global data sharing initiative

Liesbet M Peeters, Tina Parciak, Clare Walton, Lotte Geys, Yves Moreau, Edward De Brouwer, Daniele Raimondi, Ashkan Pirmani, Tomas Kalincik, Gilles Edan, Steve Simpson-Yap, Luc De Raedt, Yann Dauxais, Clement Gautrais, Paulo R Rodrigues, Landon McKenna, Nikola Lazovski, Jan Hillert, Lars Forsberg, Tim Spelman, et al.

Journal article  |  2020  |  Multiple Sclerosis Journal

BACKGROUND: We need high-quality data to assess the determinants for COVID-19 severity in people with MS (PwMS). Several studies h..

Perceived cognitive impairment is associated with sexual dysfunction in people with multiple sclerosis: a 2.5-year follow-up study of a large international cohort

Jing Wu, George A Jelinek, Tracey Weiland, Anna Karin Hedström, Lars Alfredsson, Sandra Neate, Alysha De Livera, Nupur Nag, Steve Simpson-Yap

Journal article  |  2020  |  Multiple Sclerosis and Related Disorders

SF-6D health state utilities for lifestyle, sociodemographic and clinical characteristics of a large international cohort of people with multiple sclerosis

Julie A Campbell, George A Jelinek, Tracey J Weiland, Nupur Nag, Sandra L Neate, Andrew J Palmer, Brendan Mulhern, Alysha De Livera, Steve Simpson-Yap

Journal article  |  2020  |  Quality of Life Research

BACKGROUND: While many studies have examined the impacts of multiple sclerosis (MS) on health-related quality of life (HRQoL), non..

Validation of 0-10 MS symptom scores in the Australian multiple sclerosis longitudinal study

Yan Zhang, Bruce V Taylor, Steve Simpson, Leigh Blizzard, Andrew J Palmer, Ingrid van der Mei

Journal article  |  2020  |  Multiple Sclerosis and Related Disorders

BACKGROUND: Multiple sclerosis (MS) symptom measurements often use multiple-item scales per symptom, creating a high burden when m..

Modelling the impact of multiple sclerosis on life expectancy, quality-adjusted life years and total lifetime costs: Evidence from Australia

Andrew J Palmer, Ingrid van der Mei, Bruce Taylor, Philip M Clarke, Steve Simpson, Hasnat Ahmad

Journal article  |  2020  |  Multiple Sclerosis Journal

OBJECTIVES: To quantify life expectancy (LE), quality-adjusted life years (QALYs) and total lifetime societal costs for a hypothet..

Predictors of Change in Employment Status and Associations with Quality of Life: A Prospective International Study of People with Multiple Sclerosis

Claudia H Marck, Zoe Aitken, Steve Simpson, Tracey J Weiland, Anne Kavanagh, George A Jelinek

Journal article  |  2020  |  Journal of Occupational Rehabilitation

Purpose This prospective international study aimed to assess the changes in employment, and predictors thereof, and associated cha..

Determinants of self-reported adherence to popular diets recommended for people living with multiple sclerosis

M Jakaria, G Jelinek, T Weiland, A De Livera, S Neate, K Taylor, W Bevens, N Nag, S Simpson

Conference Proceedings  |  2020  |  MULTIPLE SCLEROSIS JOURNAL

Longitudinal associations of modifiable lifestyle factors with positive depression-screen over 2.5-years in an international cohort of people living with multiple sclerosis

KL Taylor, S Simpson, GA Jelinek, SL Neate, AM De Livera, CR Brown, E O'Kearney, CH Marck, TJ Weiland

Conference Proceedings  |  2020  |  MULTIPLE SCLEROSIS JOURNAL

Mastery significantly associated with physical and mental health-related quality of life in two independent international samples of people with MS

E O'Kearney, A De Livera, S Simpson, GA Jelinek, SL Neate, W Bevens, KL Taylor, CR Brown, TJ Weiland

Conference Proceedings  |  2020  |  MULTIPLE SCLEROSIS JOURNAL

Associations of demographic and clinical factors with positive depression-screen over 2.5-years in an international prospective cohort of people living with multiple sclerosis

S Simpson, K Taylor, GA Jelinek, AM De Livera, CR Brown, E O'Kearney, SL Neate, W Bevens, TJ Weiland

Conference Proceedings  |  2020  |  MULTIPLE SCLEROSIS JOURNAL

Change in Multiple Sclerosis Prevalence Over Time in Australia 2010-2017 Utilising Disease Modifying Therapy Prescription Data

JA Campbell, S Simpson, H Ahmed, BV Taylor, I van der Mei, AJ Palmer

Conference Proceedings  |  2020  |  MULTIPLE SCLEROSIS JOURNAL

Depression and pain have the largest impact on the quality of life in people with MS, irrespective of MS phenotype

Y Zhang, BV Taylor, S Simpson, L Blizzard, AJ Palmer, I van der Mei

Conference Proceedings  |  2020  |  MULTIPLE SCLEROSIS JOURNAL

Mastery is associated with greater physical and mental health-related quality of life in two international cohorts of people with multiple sclerosis

EL O'Kearney, CR Brown, GA Jelinek, SL Neate, KT Taylor, W Bevens, AM De Livera, S Simpson, TJ Weiland

Journal article  |  2020  |  Multiple Sclerosis and Related Disorders

BACKGROUND: Mastery is the sense of being in control of one's life and improvement in mastery may help to enhance quality of life...

Increasing prevalence of primary biliary cholangitis in Victoria, Australia

Janine French, Ingrid van der Mei, Steve Simpson, Justin Ng, Peter Angus, John Lubel, Amanda Nicoll, Siddharth Sood, Stuart K Roberts, William Kemp, Niranjan Arachchi, Anouk Dev, Alexander Thompson, Paul J Gow

Journal article  |  2019  |  Journal of Gastroenterology and Hepatology

BACKGROUND AND AIM: The prevalence of primary biliary cholangitis (PBC) reported in different countries varies significantly and i..

Estimation of annual probabilities of changing disability levels in Australians with relapsing-remitting multiple sclerosis

Hasnat Ahmad, Ingrid van der Mei, Bruce Taylor, Robyn M Lucas, Anne-Louise Ponsonby, Jeannette Lechner-Scott, Keith Dear, Patricia Valery, Philip M Clarke, Steve Simpson, Andrew J Palmer, Terry Dwyer, Leigh Blizzard, Simon Broadley, Trevor Kilpatrick, David Williams, Jeanette Lechner-Scott, Cameron Shaw, Caron Chapman, Alan Coulthard, et al.

Journal article  |  2019  |  Multiple Sclerosis Journal

BACKGROUND: Transition probabilities are the engine within many health economics decision models. However, the probabilities of pr..

Latitude continues to be significantly associated with the prevalence of multiple sclerosis: an updated meta-analysis

Steve Simpson, Wendy Wang, Peter Otahal, Leigh Blizzard, Ingrid AF van der Mei, Bruce V Taylor

Conference Proceedings  |  2019  |  Journal of Neurology, Neurosurgery & Psychiatry

Redefining the Multiple Sclerosis Severity Score (MSSS): The effect of sex and onset phenotype

Yuan Zhou, Suzi B Claflin, Jim Stankovich, Ingrid van der Mei, Steve Simpson, Richard H Roxburgh, Tomas Kalincik, Leigh Blizzard, Alessandra Lugaresi, Raed Alroughani, Seyed Aidin Sajedi, Helmut Butzkueven, Eugenio Pucci, Daniele LA Spitaleri, Franco Granella, Edgardo Cristiano, Bassem Yamout, Stella Hughes, Riadh Gouider, Jose Luis Sanchez Menoyo, et al.

Journal article  |  2019  |  Multiple Sclerosis Journal

BACKGROUND: The Multiple Sclerosis Severity Score (MSSS) is a widely used measure of the disability progression rate. However, the..

Comorbidities are prevalent and detrimental for employment outcomes in people of working age with multiple sclerosis

Jing Chen, Bruce Taylor, Tania Winzenberg, Andrew J Palmer, Andrea Kirk-Brown, Pieter van Dijk, Steve Simpson, Leigh Blizzard, Ingrid van der Mei

Journal article  |  2019  |  Multiple Sclerosis Journal

Modifiable factors associated with depression and anxiety in multiple sclerosis

Claudia R Gascoyne, Steve Simpson, Jing Chen, Ingrid van der Mei, Claudia H Marck

Journal article  |  2019  |  Acta Neurologica Scandinavica

OBJECTIVES: Modifiable lifestyle factors are implicated in multiple sclerosis (MS) symptoms but their role in mood is unclear. Thi..

Cervical determinants of anal HPV infection and high-grade anal lesions in women: a collaborative pooled analysis.

Chunqing Lin, Jiri Slama, Paula Gonzalez, Marc T Goodman, Ningshao Xia, Aimée R Kreimer, Ting Wu, Nancy A Hessol, Yurii Shvetsov, Ana P Ortiz, Beatriz Grinsztejn, Anna-Barbara Moscicki, Isabelle Heard, María Del Refugio González Losa, Erna M Kojic, Maarten F Schim van der Loeff, Feixue Wei, Adhemar Longatto-Filho, Zizipho A Mbulawa, Joel M Palefsky, et al.

Journal article  |  2019  |  The Lancet Infectious Diseases

BACKGROUND: Cervical cancer screening might contribute to the prevention of anal cancer in women. We aimed to investigate if routi..

On the path together: Experiences of partners of people with multiple sclerosis of the impact of lifestyle modification on their relationship

Sandra L Neate, Keryn L Taylor, George A Jelinek, Alysha M De Livera, Steve Simpson, William Bevens, Tracey J Weiland

Journal article  |  2019  |  Health & Social Care in the Community

Multiple sclerosis (MS) has a major impact on the relationship of couples living with the illness. Although some positives of deal..

Change in multiple sclerosis prevalence over time in Australia 2010-2017 utilising disease-modifying therapy prescription data

Julie A Campbell, Steve Simpson, Hasnat Ahmad, Bruce Taylor, Ingrid van der Mei, Andrew J Palmer

Journal article  |  2019  |  Multiple Sclerosis Journal

OBJECTIVE: Determine the prevalence of multiple sclerosis (MS) in Australia in 2017 using MS-specific disease-modifying therapy (D..

Estimating MS-related work productivity loss and factors associated with work productivity loss in a representative Australian sample of people with multiple sclerosis

Jing Chen, Bruce Taylor, Andrew J Palmer, Andrea Kirk-Brown, Pieter van Dijk, Steve Simpson, Leigh Blizzard, Ingrid van der Mei

Journal article  |  2019  |  Multiple Sclerosis Journal

Lipid-related genetic polymorphisms significantly modulate the association between lipids and disability progression in multiple sclerosis

Yan Zhang, Yuan Zhou, Ingrid AF van der Mei, Steve Simpson, Anne-Louise Ponsonby, Robyn M Lucas, Prudence Tettey, Jac Charlesworth, Karam Kostner, Bruce V Taylor, Keith Dear, Terry Dwyer, Leigh Blizzard, Simon Broadley, Trevor Kilpatrick, David Williamsand Jeanette Lechner-Scott, Cameron Shawand Caron Chapman, Alan Coulthard, Michael P Pender, Patricia Valery

Conference Proceedings  |  2019  |  Journal of Neurology, Neurosurgery & Psychiatry

Healthy lifestyle is associated with lower frequency and severity of depression, but not anxiety, in Australian people with multiple sclerosis

Claudia R Gascoyne, Steve Simpson, Jing Chen, Ingrid van der Mei, Claudia H Marck

Conference Proceedings  |  2019  |  MULTIPLE SCLEROSIS JOURNAL

Polymorphism in the serotonin transporter gene polymorphisms (5-HTTLPR) modifies the association between significant life events and depression in people with multiple sclerosis

Alice Saul, Bruce Taylor, Steve Simpson, Anne-Louise Ponsonby, Leigh Blizzard, Terence Dwyer, Brendan McMorran, Brenda Wood, Ingrid AF van der Mei

Journal article  |  2019  |  Multiple Sclerosis Journal

Associations of demographic and clinical factors with depression over 2.5-years in an international prospective cohort of people living with MS

Steve Simpson, Keryn L Taylor, George A Jelinek, Alysha M De Livera, Chelsea R Brown, Emily O'Kearney, Sandra L Neate, William Bevens, Tracey J Weiland

Journal article  |  2019  |  Multiple Sclerosis and Related Disorders

Differential multiple sclerosis treatment allocation between Australia and New Zealand associated with clinical outcomes but not mood or quality of life

Aung Zaw Zaw Phyo, George A Jelinek, Chelsea R Brown, Emily O'Kearney, Sandra L Neate, Alysha M De Livera, Keryn L Taylor, William Bevens, Steve Simpson, Tracey J Weiland

Journal article  |  2019  |  Multiple Sclerosis and Related Disorders

Vitamin D deficiency is an etiological factor for MS - Commentary

Steve Simpson, Ingrid van der Mei

Journal article  |  2019  |  Multiple Sclerosis Journal

Health Outcomes and Lifestyle In a Sample of People with Multiple Sclerosis (HOLISM): longitudinal and validation cohorts

TJ Weiland, AM De Livera, CR Brown, GA Jelinek, Z Aitken, Jr S Simpson, SL Neate, KT Taylor, E O'Kearney, W Bevens, CH Marck

Conference Proceedings  |  2019  |  MULTIPLE SCLEROSIS JOURNAL

Mastery is significantly associated with greater physical and mental health-related quality of life in two independently recruited international samples of people with multiple sclerosis

Emily O'Kearney, Alysha De Livera, Steven Simpson, George A Jelinek, Sandra L Neate, William Bevens, Keryn L Taylor, Chelsea R Brown, Tracey J Weiland

Conference Proceedings  |  2019  |  MULTIPLE SCLEROSIS JOURNAL

Differential multiple sclerosis treatment allocation between Australia & New Zealand associated with clinical outcomes but not mood or quality of life

Aung Zaw Zaw Phyo, Alysha M De Livera, George A Jelinek, Chelsea R Brown, Emily O'Kearney, Sandra L Neate, Keryn L Taylor, William Bevens, Steve Simpson, Tracey J Weiland

Conference Proceedings  |  2019  |  MULTIPLE SCLEROSIS JOURNAL

Associations of demographic and clinical factors with positive depression-screen over 2.5-years in an international prospective cohort of people living with multiple sclerosis

Steve Simpson, Keryn Taylor, George A Jelinek, Alysha M De Livera, Chelsea R Brown, Emily O'Kearney, Sandra L Neate, William Bevens, Tracey J Weiland

Conference Proceedings  |  2019  |  MULTIPLE SCLEROSIS JOURNAL

Role of PCK1 gene on oil tea-induced glucose homeostasis and type 2 diabetes: an animal experiment and a case-control study

Qiantu Hu, Huafeng Chen, Yanli Zuo, Qin He, Xuan He, Steve Simpson, Wei Huang, Hui Yang, Haiying Zhang, Rui Lin

Journal article  |  2019  |  Nutrition & Metabolism

Self-reported cognitive function in a large international cohort of people with multiple sclerosis: associations with lifestyle and other factors

PL Jelinek, S Simpson, CR Brown, GA Jelinek, CH Marck, AM De Livera, E O'Kearney, KL Taylor, SL Neate, TJ Weiland

Journal article  |  2019  |  EUROPEAN JOURNAL OF NEUROLOGY

Patient-reported outcomes are worse for progressive-onset multiple sclerosis than relapse-onset multiple sclerosis, particularly early in the disease process

Y Zhang, BV Taylor, S Simpson, L Blizzard, I van der Mei

Journal article  |  2019  |  European Journal of Neurology

Keeping people with MS in the workforce through effective treatment

Steve Simpson

Journal article  |  2019  |  Journal of Neurology, Neurosurgery & Psychiatry

Apolipoprotein E4 Mediates the Association Between Midlife Dyslipidemia and Cerebral Amyloid in Aging Women

Cassandra Szoeke, Alicia M Goodwill, Alexandra Gorelik, Lorraine Dennerstein, Karen Caeyenberghs, Steven Simpson, Edward Hill, Stephen Campbell

Journal article  |  2019  |  Journal of Alzheimer's Disease

Vitamin D supplementation to prevent acute respiratory infections: individual participant data meta-analysis.

Adrian R Martineau, David A Jolliffe, Lauren Greenberg, John F Aloia, Peter Bergman, Gal Dubnov-Raz, Susanna Esposito, Davaasambuu Ganmaa, Adit A Ginde, Emma C Goodall, Cameron C Grant, Wim Janssens, Megan E Jensen, Conor P Kerley, Ilkka Laaksi, Semira Manaseki-Holland, David Mauger, David R Murdoch, Rachel Neale, Judy R Rees, et al.

Journal article  |  2019  |  Health Technology Assessment

BACKGROUND: Randomised controlled trials (RCTs) exploring the potential of vitamin D to prevent acute respiratory infections have ..

Health Outcomes and Lifestyle in a Sample of People With Multiple Sclerosis (HOLISM): Longitudinal and Validation Cohorts

Tracey J Weiland, Alysha M De Livera, Chelsea R Brown, George A Jelinek, Zoe Aitken, Steve L Simpson Jr, Sandra L Neate, Keryn L Taylor, Emily O'Kearney, William Bevens, Claudia H Marck

Journal article  |  2018  |  FRONTIERS IN NEUROLOGY

Longitudinal Associations of the Healthy Lifestyle Index Score With Quality of Life in People With Multiple Sclerosis: A Prospective Cohort Study

Teng Leong, Tracey J Weiland, George A Jelinek, Steve Simpson, Chelsea R Brown, Sandra L Neate, Keryn L Taylor, Emily O'Kearney, Elasma Milanzi, Alysha M De Livera

Journal article  |  2018  |  FRONTIERS IN NEUROLOGY

Effects of multiple sclerosis disease-modifying therapies on employment measures using patient-reported data

Jing Chen, Bruce V Taylor, Leigh Blizzard, Steve Simpson, Andrew J Palmer, Ingrid AF van der Mei

Journal article  |  2018  |  Journal of Neurology, Neurosurgery & Psychiatry

Longitudinal Associations of Modifiable Lifestyle Factors With Positive Depression-Screen Over 2.5-Years in an International Cohort of People Living With Multiple Sclerosis

Keryn L Taylor, Steve Simpson, George A Jelinek, Sandra L Neate, Alysha M De Livera, Chelsea R Brown, Emily O'Kearney, Claudia H Marck, Tracey J Weiland

Journal article  |  2018  |  FRONTIERS IN PSYCHIATRY

Mastery is significantly associated with greater physical and mental health-related quality of life in two independently recruited international samples of people with multiple sclerosis

E O'Kearney, A De Livera, S Simpson, G Jelinek, S Neate, W Bevens, K Taylor, C Brown, T Weiland

Conference Proceedings  |  2018  |  MULTIPLE SCLEROSIS JOURNAL

Differential multiple sclerosis treatment allocation between Australia & New Zealand impacts on clinical course but not quality of life

AZZ Phyo, A De Livera, G Jelinek, C Brown, E O'Kearney, S Neate, K Taylor, W Bevens, S Simpson, T Weiland

Conference Proceedings  |  2018  |  MULTIPLE SCLEROSIS JOURNAL

Three dietary patterns consistently demonstrated over five years of follow-up in early multiple sclerosis: results from the AusLong Study

S Simpson, W Oddy, B Taylor, R Lucas, L Black, A-L Ponsonby, L Blizzard, I van der Mei

Conference Proceedings  |  2018  |  MULTIPLE SCLEROSIS JOURNAL

Validation of the assessment of self-reported MS symptom severity using single-item 0-10 numeric rating scales

Y Zhang, S Simpson, B Taylor, I van der Mei

Conference Proceedings  |  2018  |  MULTIPLE SCLEROSIS JOURNAL

Demographics, lifestyle risk factors, and health outcomes of two large international samples of people with multiple sclerosis: HOLISM Longitudinal and Validation cohorts

T Weiland, A De Livera, C Brown, G Jelinek, Z Aitken, S Simpson, S Neate, K Taylor, E O'Kearney, W Bevens, C Marck

Conference Proceedings  |  2018  |  MULTIPLE SCLEROSIS JOURNAL

Oil tea improves glucose and lipid levels and alters gut microbiota in type 2 diabetic mice

Rui Lin, Xuan He, Huafeng Chen, Qin He, Ziting Yao, Yuanfan Li, Hui Yang, Steve Simpson

Journal article  |  2018  |  Nutrition Research

Onset Symptoms, Tobacco Smoking, and Progressive-Onset Phenotype Are Associated With a Delayed Onset of Multiple Sclerosis, and Marijuana Use With an Earlier Onset

Chunrong Tao, Steve Simpson, Bruce V Taylor, Leigh Blizzard, Robyn M Lucas, Anne-Louise Ponsonby, Simon Broadley, Ingrid van der Mei

Journal article  |  2018  |  Frontiers in Neurology

Common genetic variation within miR-146a predicts disease onset and relapse in multiple sclerosis

Yuan Zhou, Ming Chen, Steve Simpson, Robyn M Lucas, Jac C Charlesworth, Nicholas Blackburn, Ingrid van der Mei, Anne-Louise Ponsonby, Bruce V Taylor

Journal article  |  2018  |  Neurological Sciences

Sun Exposure across the Life Course Significantly Modulates Early Multiple Sclerosis Clinical Course

Steve Simpson, Ingrid van der Mei, Robyn M Lucas, Anne-Louise Ponsonby, Simon Broadley, Leigh Blizzard, Bruce Taylor

Journal article  |  2018  |  Frontiers in Neurology

The Role of Vitamin D in Multiple Sclerosis: Biology and Biochemistry, Epidemiology and Potential Roles in Treatment

Steve Simpson, Ingrid van der Mei, Bruce Taylor

Journal article  |  2018  |  Medicinal Chemistry

The multiple sclerosis risk allele within the AHI1 gene is associated with relapses in children and adults

Jennifer S Graves, Lisa F Barcellos, Steve Simpson, Anita Belman, Rui Lin, Bruce V Taylor, Anne-Louise Ponsonby, Terence Dwyer, Lauren Krupp, Emmanuelle Waubant, Ingrid AF van der Mei

Journal article  |  2018  |  Multiple Sclerosis and Related Disorders

Vitamin D status is associated with executive function a decade later: Data from the Women's Healthy Ageing Project

Alicia M Goodwill, Stephen Campbell, Steven Simpson, Maria Bisignano, Cherie Chiang, Lorraine Dennerstein, Cassandra Szoeke

Journal article  |  2018  |  Maturitas

Positive stressful life events are associated with lower hazard of relapses in early multiple sclerosis

Ingrid van der Mei, Chunrong Tao, Steve Simpson, Bruce Taylor, Robyn Lucas, Anne-Louise Ponsonby

Conference Proceedings  |  2017  |  MULTIPLE SCLEROSIS JOURNAL

Modifiable lifestyle factors at baseline could not influence the clinical course of multiple sclerosis

Ingrid van der Mei, Chunrong Tao, Steve Simpson, Bruce Taylor, Robyn Lucas, Anne-Louise Ponsonby

Conference Proceedings  |  2017  |  MULTIPLE SCLEROSIS JOURNAL

Genetic variation in the gene LRP2 increases relapse risk in multiple sclerosis

Yuan Zhou, Jennifer S Graves, Steve Simpson, Jac C Charlesworth, Ingrid van der Mei, Emmanuelle Waubant, Lisa F Barcellos, Anita Belman, Lauren Krupp, Robyn Lucas, Anne-Louise Ponsonby, Bruce Taylor

Conference Proceedings  |  2017  |  MULTIPLE SCLEROSIS JOURNAL

Polymorphism in the serotonin transporter gene polymorphisms (5-HTTLPR) modifies the association between significant life events and depression in people with Multiple Sclerosis

Alice Saul, Ingrid van Der Mei, Bruce Taylor, Steve Simpson, Anne-Louise Ponsonby, Terrence Dwyer, Brendan McMorran

Conference Proceedings  |  2017  |  MULTIPLE SCLEROSIS JOURNAL

Genetic variation in the gene LRP2 increases relapse risk in multiple sclerosis

Yuan Zhou, Jennifer S Graves, Steve Simpson, Jac C Charlesworth, Ingrid van der Mei, Emmanuelle Waubant, Lisa F Barcellos, Anita Belman, Lauren Krupp, Robyn Lucas, Anne-Louise Ponsonby, Bruce V Taylor

Journal article  |  2017  |  Journal of Neurology, Neurosurgery & Psychiatry

Genetic variation in the gene LRP2 increases relapse risk in multiple sclerosis

Y Zhou, J Graves, S Simpson, J Charlesworth, I van der Mei, E Waubant, LF Barcellos, A Belman, R Lucas, A-L Ponsonby, B Taylor

Conference Proceedings  |  2017  |  MULTIPLE SCLEROSIS JOURNAL

Midsagittal corpus callosum area and conversion to multiple sclerosis after clinically isolated syndrome: A multicentre Australian cohort study

Cara Odenthal, Steve Simpson, Justin Oughton, Ingrid van der Mei, Stephen Rose, Jurgen Fripp, Robyn Lucas, Bruce Taylor, Keith Dear, Anne-Louise Ponsonby, Alan Coulthard

Journal article  |  2017  |  Journal of Medical Imaging and Radiation Oncology

The impact of multiple sclerosis severity on health state utility values: Evidence from Australia

Hasnat Ahmad, Bruce V Taylor, Ingrid van der Mei, Sam Colman, Beth A O'Leary, Monique Breslin, Andrew J Palmer

Journal article  |  2017  |  Multiple Sclerosis Journal

Stressful life events and the risk of initial central nervous system demyelination

Alice Saul, Anne-Louise Ponsonby, Robyn M Lucas, Bruce V Taylor, Steve Simpson, Patricia Valery, Terence Dwyer, Trevor J Kilpatrick, Michael P Pender, Ingrid AF van der Mei

Journal article  |  2017  |  Multiple Sclerosis Journal

An adverse lipid profile and increased levels of adiposity significantly predict clinical course after a first demyelinating event

Prudence Tettey, Steve Simpson, Bruce Taylor, Anne-Louise Ponsonby, Robyn M Lucas, Terence Dwyer, Karam Kostner, Ingrid AF van der Mei

Journal article  |  2017  |  Journal of Neurology, Neurosurgery & Psychiatry

Variation within MBP gene predicts disease course in multiple sclerosis

Yuan Zhou, Steve Simpson, Jac C Charlesworth, Ingrid van der Mei, Robyn M Lucas, Anne-Louise Ponsonby, Bruce V Taylor

Journal article  |  2017  |  Brain and Behavior

Response to Attarian regarding article

S Simpson, B Taylor, I van der Mei

Journal article  |  2017  |  Acta Neurologica Scandinavica

Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data

Adrian R Martineau, David A Jolliffe, Richard L Hooper, Lauren Greenberg, John F Aloia, Peter Bergman, Gal Dubnov-Raz, Susanna Esposito, Davaasambuu Ganmaa, Adit A Ginde, Emma C Goodall, Cameron C Grant, Christopher J Griffiths, Wim Janssens, Ilkka Laaksi, Semira Manaseki-Holland, David Mauger, David R Murdoch, Rachel Neale, Judy R Rees, et al.

Journal article  |  2017  |  BMJ

The Role of Genetic Susceptibility Variants in Predicting Clinical Course in Multiple Sclerosis: A Cohort Study

Gongbu Pan, Steve Simpson, Ingrid van der Mei, Jac C Charlesworth, Robyn Lucas, Anne-Louise Ponsonby, Yuan Zhou, Feitong Wu, Bruce V Taylor

Conference Proceedings  |  2017  |  MULTIPLE SCLEROSIS JOURNAL

Association between human herpesvirus & human endogenous retrovirus and MS onset & progression

Chunrong Tao, Steve Simpson, Bruce V Taylor, Ingrid van der Mei

Journal article  |  2017  |  Journal of the Neurological Sciences

Sexuality-related attitudes significantly modulate demographic variation in sexual health literacy in Tasmanian university students

Steve Simpson, Christine Clifford, Michael G Quinn, Kaz Ross, Neil Sefton, Louise Owen, Leigh Blizzard, Richard Turner

Journal article  |  2017  |  Sexual Health

Anxiety, depression and fatigue at 5-year review following CNS demyelination

S Simpson, H Tan, P Otahal, B Taylor, A-L Ponsonby, RM Lucas, L Blizzard, PC Valery, J Lechner-Scott, C Shaw, D Williams, I van der Mei

Journal article  |  2016  |  Acta Neurologica Scandinavica

Higher latitude is significantly associated with an earlier age of disease onset in multiple sclerosis

Chunrong Tao, Steve Simpson, Ingrid van der Mei, Leigh Blizzard, Eva Havrdova, Dana Horakova, Vahid Shaygannejad, Alessandra Lugaresi, Guillermo Izquierdo, Maria Trojano, Pierre Duquette, Marc Girard, Franois Grand'Maison, Pierre Grammond, Raed Alroughani, Murat Terzi, Celia Oreja-Guevara, Seyed Aidin Sajedi, Gerardo Iuliano, Patrizia Sola, et al.

Journal article  |  2016  |  JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Role of genetic susceptibility variants in predicting clinical course in multiple sclerosis: a cohort study

Gongbu Pan, Steve Simpson, Ingrid van der Mei, Jac C Charlesworth, Robyn Lucas, Anne-Louise Ponsonby, Yuan Zhou, Feitong Wu, Bruce V Taylor

Journal article  |  2016  |  Journal of Neurology, Neurosurgery & Psychiatry

Genetic loci for Epstein-Barr virus nuclear antigen-1 are associated with risk of multiple sclerosis

Yuan Zhou, Gu Zhu, Jac C Charlesworth, Steve Simpson, Rohina Rubicz, Harald HH Goring, Nikolaos A Patsopoulos, Caroline Laverty, Feitong Wu, Anjali Henders, Jonathan J Ellis, Ingrid van der Mei, Grant W Montgomery, John Blangero, Joanne E Curran, Matthew P Johnson, Nicholas G Martin, Dale R Nyholt, Bruce V Taylor

Journal article  |  2016  |  Multiple Sclerosis Journal

Non-Obese Diabetes and Its Associated Factors in an Underdeveloped Area of South China, Guangxi

Zhenzhu Tang, Zhifeng Fang, Wei Huang, Zhanhua Liu, Yuzhu Chen, Zhongyou Li, Ting Zhu, Qichun Wang, Steve Simpson, Bruce V Taylor, Rui Lin

Journal article  |  2016  |  International Journal of Environmental Research and Public Health

Anti-HHV6 IgG levels are associated with hazard of conversion to clinically definite multiple sclerosis after CIS

C Tao, S Simpson, R Lucas, B Taylor, I Van der Mei

Conference Proceedings  |  2016  |  MULTIPLE SCLEROSIS JOURNAL

Synergetic and antagonistic effects of combined calcitriol and interferon-beta treatment on cytokine production by stimulated PBMCs

Steve Simpson, Niall Stewart, Ingrid van der Mei, Leigh Blizzard, Bruce V Taylor

Journal article  |  2016  |  Journal of Neuroimmunology

Front-to-back & dabbing wiping behaviour post-toilet associated with anal neoplasia & HR-HPV carriage in women with previous HPV-mediated gynaecological neoplasia

Steve Simpson, Penny Blomfield, Alyssa Cornall, Sepehr N Tabrizi, Leigh Blizzard, Richard Turner

Journal article  |  2016  |  Cancer Epidemiology

Frequency of Comorbidities and Their Association with Clinical Disability and Relapse in Multiple Sclerosis

Prudence Tettey, Dylan Siejka, Steve Simpson, Bruce Taylor, Leigh Blizzard, Anne-Louise Ponsonby, Terence Dwyer, Ingrid van der Mei

Journal article  |  2016  |  Neuroepidemiology

The epidemiology of multiple sclerosis in the Isle of Man: 2006-2011

S Simpson, S Mina, H Morris, S Mahendran, B Taylor, M Boggild

Journal article  |  2015  |  Acta Neurologica Scandinavica

Weekly cholecalciferol supplementation results in significant reductions in infection risk among the vitamin D deficient: results from the CIPRIS pilot RCT

Steve Simpson, Ingrid van der Mei, Niall Stewart, Leigh Blizzard, Prudence Tettey, Bruce Taylor

Journal article  |  2015  |  BMC Nutrition

Higher offspring number is significantly associated with a later age of disease onset in multiple sclerosis

Chunrong Tao, Bruce V Taylor, Robyn M Lucas, Anne-Louise Ponsonby, Ingrid Van der Mei

Conference Proceedings  |  2015  |  Journal of Neurology, Neurosurgery & Psychiatry

Latitude significantly predicts an earlier age of disease onset in multiple sclerosis

C Tao, S Simpson, I van der Mei, L Blizzard, B Taylor

Conference Proceedings  |  2015  |  MULTIPLE SCLEROSIS JOURNAL

Admission blood glucose predicts mortality and length of stay in patients admitted through the emergency department

WG Martin, J Galligan, S Simpson, T Greenaway, J Burgess

Journal article  |  2015  |  Internal Medicine Journal

The role of epidemiology in MS research: Past successes, current challenges and future potential

Steve Simpson, Bruce V Taylor, Ingrid van der Mei

Journal article  |  2015  |  Multiple Sclerosis Journal

Modulating effects of WT1 on interferon-beta-vitamin D association in MS

R Lin, BV Taylor, J Charlesworth, I van der Mei, L Blizzard, N Stewart, A-L Ponsonby, T Dwyer, F Pittas, S Simpson

Journal article  |  2015  |  Acta Neurologica Scandinavica

Genetic variation in PBMC-produced IFN-gamma and TNF-alpha associations with relapse in multiple sclerosis

Yuan Zhou, Bruce Taylor, Ingrid van der Mei, Niall Stewart, Jac Charlesworth, Leigh Blizzard, Anne-Louise Ponsonby, Terence Dwyer, Fotini Pittas, Steve Simpson

Journal article  |  2015  |  Journal of the Neurological Sciences

Stimulated PBMC-produced IFN-gamma and TNF-alpha are associated with altered relapse risk in multiple sclerosis: results from a prospective cohort study

Steve Simpson, Niall Stewart, Ingrid van der Mei, Petr Otahal, Jac Charlesworth, Anne-Louise Ponsonby, Leigh Blizzard, Terence Dwyer, Fotini Pittas, Peter Gies, Bruce Taylor

Journal article  |  2015  |  Journal of Neurology, Neurosurgery & Psychiatry

The co-occurrence of multiple sclerosis and type 1 diabetes: Shared aetiologic features and clinical implication for MS aetiology

Prudence Tettey, Steve Simpson, Bruce V Taylor, Ingrid AF van der Mei

Journal article  |  2015  |  Journal of the Neurological Sciences

Sexual health literacy of the student population of the University of Tasmania: results of the RUSSL Study

Steve Simpson, Christine Clifford, Kaz Ross, Neil Sefton, Louise Owen, Leigh Blizzard, Richard Turner

Journal article  |  2015  |  Sexual Health

Vascular comorbidities in the onset and progression of multiple sclerosis

Prudence Tettey, Steve Simpson, Bruce V Taylor, Ingrid AF van der Mei

Journal article  |  2014  |  Journal of the Neurological Sciences

EBV & HHV6 reactivation is infrequent and not associated with MS clinical course

S Simpson, B Taylor, J Burrows, S Burrows, DE Dwyer, J Taylor, A-L Ponsonby, L Blizzard, T Dwyer, F Pittas, I van der Mei

Journal article  |  2014  |  Acta Neurologica Scandinavica

An adverse lipid profile is associated with disability and progression in disability, in people with MS

Prudence Tettey, Steve Simpson, Bruce Taylor, Leigh Blizzard, Anne-Louise Ponsonby, Terence Dwyer, Karam Kostner, Ingrid van der Mei

Journal article  |  2014  |  Multiple Sclerosis Journal

The Scandinavian paradox revisited: Editorial comment on Berg-Hansen et al. 'High prevalence and no latitude gradient of multiple sclerosis in Norway'

Steve Simpson, Bruce V Taylor

Journal article  |  2014  |  Multiple Sclerosis Journal

Idiopathic granulomatous hypophysitis: a systematic review of 82 cases in the literature

Benjamin HM Hunn, William G Martin, Steven Simpson, Catriona A Mclean

Journal article  |  2014  |  Pituitary

Adverse lipid profile is not associated with relapse risk in MS: Results from an observational cohort study

Prudence Tettey, Steve Simpson, Bruce Taylor, Leigh Blizzard, Anne-Louise Ponsonby, Terence Dwyer, Karam Kostner, Ingrid van der Mei

Journal article  |  2014  |  Journal of the Neurological Sciences

Novel modulating effects of PKC family genes on the relationship between serum vitamin D and relapse in multiple sclerosis

Rui Lin, Bruce V Taylor, Steve Simpson, Jac Charlesworth, Anne-Louise Ponsonby, Fotini Pittas, Terence Dwyer, Ingrid AF van der Mei

Journal article  |  2014  |  Journal of Neurology, Neurosurgery and Psychiatry

Association between multiple sclerosis risk-associated SNPs and relapse and disability - a prospective cohort study

Rui Lin, Bruce V Taylor, Steve Simpson, Jac Charlesworth, Anne-Louise Ponsonby, Fotini Pittas, Terry Dwyer, Ingrid van der Mei

Journal article  |  2014  |  Multiple Sclerosis

Higher levels of reported sun exposure, and not vitamin D status, are associated with less depressive symptoms and fatigue in multiple sclerosis

S Knippenberg, J Damoiseaux, Y Bol, R Hupperts, BV Taylor, A-L Ponsonby, T Dwyer, S Simpson, IAF van der Mei

Journal article  |  2014  |  Acta Neurologica Scandinavica

The potential role of epigenetic modifications in the heritability of multiple sclerosis

Yuan Zhou, Steve Simpson, Adele F Holloway, Jac Charlesworth, Ingrid van der Mei, Bruce V Taylor

Journal article  |  2014  |  Multiple Sclerosis Journal

Meta-Analyses to Investigate Gene-Environment Interactions in Neuroepidemiology

IAF van der Mei, P Otahal, S Simpson, B Taylor, T Winzenberg

Journal article  |  2014  |  Neuroepidemiology

A novel method for calculating prevalence of multiple sclerosis in Australia

Andrew J Palmer, Peta L Hitchens, Steve Simpson, Beth O'Leary, Sam Colman, Bruce V Taylor

Journal article  |  2013  |  Multiple Sclerosis Journal

Assessing possible selection bias in a national voluntary MS longitudinal study in Australia

Bruce V Taylor, Andrew Palmer, Steve Simpson, Robyn Lucas, Rex D Simmons, Deborah Mason, John Pearson, Glynnis Clarke, Clive Sabel, Ernie Willoughby, Anne Richardson, David Abernethy

Journal article  |  2013  |  Multiple Sclerosis Journal

Geographical Variations in Sex Ratio Trends over Time in Multiple Sclerosis

Maria Trojano, Guglielmo Lucchese, Giusi Graziano, Bruce V Taylor, Steve Simpson, Vito Lepore, Francois Grand'Maison, Pierre Duquette, Guillermo Izquierdo, Pierre Grammond, Maria Pia Amato, Roberto Bergamaschi, Giorgio Giuliani, Cavit Boz, Raymond Hupperts, Vincent Van Pesch, Jeannette Lechner-Scott, Edgardo Cristiano, Marcela Fiol, Celia Oreja-Guevara, et al.

Journal article  |  2012  |  PLOS ONE

Interferon-beta and serum 25-hydroxyvitamin D interact to modulate relapse risk in MS

Niall Stewart, Steve Simpson, Ingrid van der Mei, Anne-Louise Ponsonby, Leigh Blizzard, Terrence Dwyer, Fotini Pittas, Darryl Eyles, Pauline Ko, Bruce V Taylor

Journal article  |  2012  |  Neurology

Anti-HHV-6 IgG titer significantly predicts subsequent relapse risk in multiple sclerosis

Steve Simpson, Bruce Taylor, Dominic E Dwyer, Janette Taylor, Leigh Blizzard, Anne-Louise Ponsonby, Fotini Pittas, Terence Dwyer, Ingrid van der Mei

Journal article  |  2012  |  Multiple Sclerosis

Four decades of anal cancer in Tasmania, Australia: what do the case data tell us?

Steve Simpson, Richard Turner

Journal article  |  2012  |  Sexual Health

Latitude is significantly associated with the prevalence of multiple sclerosis: a meta-analysis

Steve Simpson, Leigh Blizzard, Petr Otahal, Ingrid Van der Mei, Bruce Taylor

Journal article  |  2011  |  Journal of Neurology, Neurosurgery & Psychiatry

Individual and Joint Action of Environmental Factors and Risk of MS

IAF van der Mei, S Simpson, J Stankovich, BV Taylor

Journal article  |  2011  |  Neurologic Clinics

Trends in the epidemiology of multiple sclerosis in Greater Hobart, Tasmania: 1951 to 2009

Steve Simpson, Fotini Pittas, Ingrid van der Mei, Leigh Blizzard, Anne-Louise Ponsonby, Bruce Taylor

Journal article  |  2011  |  Journal of Neurology, Neurosurgery and Psychiatry

The varied mechanisms of vitamin D in the onset and clinical course of MS: potential roles in modulating other aetiologic pathways

S Simpson

Journal article  |  2011  |  Current Medical Literature – Neurology

The role of vitamin D in multiple sclerosis: implications for disease management

S Simpson

Journal article  |  2011  |  Neurodegenerative Disease Management

Higher 25-hydroxyvitamin D Is Associated with Lower Relapse Risk in Multiple Sclerosis

Steve Simpson, Bruce Taylor, Leigh Blizzard, Anne-Louise Ponsonby, Fotini Pittas, Helen Tremlett, Terence Dwyer, Peter Gies, Ingrid van der Mei

Journal article  |  2010  |  Annals of Neurology

On-line sample preconcentration in capillary electrophoresis Fundamentals and applications

Steven L Simpson, Joselito P Quirino, Shigeru Terabe

Journal article  |  2008  |  Journal of Chromatography A

High Prudent diet factor score predicts lower relapse hazard in early multiple sclerosis

Steve Simpson-Yap, Wendy H Oddy, Bruce Taylor, Robyn M Lucas, Lucinda J Black, Anne-Louise Ponsonby, Leigh Blizzard, Ingrid van der Mei, Keith Dear, Terry Dwyer, Bruce V Taylor, Simon Broadley, Trevor Kilpatrick, David Williams, Jeanette Lechner-Scott, Cameron Shaw, Caron Chapman, Alan Coulthard, Michael P Pender, Patricia Valery

Journal article  |  Multiple Sclerosis Journal

Background: Dietary patterns and their association with subsequent clinical course have not been well studied in early multiple sc..