Sifat Sharmin

Effect of Disease-Modifying Therapy on Disability in Relapsing-Remitting Multiple Sclerosis Over 15 Years.

Tomas Kalincik, Ibrahima Diouf, Sifat Sharmin, Charles Malpas, Tim Spelman, Dana Horakova, Eva Kubala Havrdova, Maria Trojano, Guillermo Izquierdo, Alessandra Lugaresi, Alexandre Prat, Marc Girard, Pierre Duquette, Pierre Grammond, Vilija Jokubaitis, Anneke van der Walt, Francois Grand'Maison, Patrizia Sola, Diana Ferraro, Vahid Shaygannejad, et al.

Journal article  |  2021  |  Neurology

OBJECTIVE: To test the hypothesis that immunotherapy prevents long-term disability in relapsing-remitting multiple sclerosis (MS),..

Association of Sustained Immunotherapy With Disability Outcomes in Patients With Active Secondary Progressive Multiple Sclerosis

Nathaniel Lizak, Charles B Malpas, Sifat Sharmin, Eva Kubala Havrdova, Dana Horakova, Guillermo Izquierdo, Sara Eichau, Alessandra Lugaresi, Pierre Duquette, Marc Girard, Alexandre Prat, Catherine Larochelle, Maria Trojano, Francois Grand'Maison, Pierre Grammond, Patrizia Sola, Diana Ferraro, Raymond Hupperts, Roberto Bergamaschi, Cavit Boz, et al.

Journal article  |  2020  |  JAMA Neurology

Importance: It is unclear whether relapses and disease-modifying therapies are associated with the rate of disability accumulation..

Disability outcomes of early cerebellar and brainstem symptoms in multiple sclerosis

Le Minh, Charles Malpas, Sifat Sharmin, Dana Horakova, Eva Havrdova, Maria Trojano, Guillermo Izquierdo, Sara Eichau, Serkan Ozakbas, Alessandra Lugaresi, Alexandre Prat, Marc Girard, Pierre Duquette, Catherine Larochelle, Raed Alroughani, Roberto Bergamaschi, Patrizia Sola, Diana Ferraro, Pierre Grammond, Francois Grand' Maison, et al.

Journal article  |  2020  |  Multiple Sclerosis Journal

BACKGROUND: Cerebellar and brainstem symptoms are common in early stages of multiple sclerosis (MS) yet their prognostic values re..

Trajectories of Mini-Mental State Examination Scores over the Lifespan in General Populations: A Systematic Review and Meta-Regression Analysis

Julius M Nagaratnam, Sifat Sharmin, Aaron Diker, Wen Kwang Lim, Andrea B Maier

Journal article  |  2020  |  Clinical Gerontologist: the journal of aging and mental health

Objectives: Over the lifespan cumulative changes to the brain lead to cognitive decline and eventually to dementia in 20-25% of ad..

Early clinical markers of aggressive multiple sclerosis

Charles B Malpas, Ali Manouchehrinia, Sifat Sharmin, Izanne Roos, Dana Horakova, Eva Kubala Havrdova, Maria Trojano, Guillermo Izquierdo, Sara Eichau, Roberto Bergamaschi, Patrizia Sola, Diana Ferraro, Alessandra Lugaresi, Alexandre Prat, Marc Girard, Pierre Duquette, Pierre Grammond, Francois Grand'Maison, Serkan Ozakbas, Vincent Van Pesch, et al.

Journal article  |  2020  |  Brain

Patients with the 'aggressive' form of multiple sclerosis accrue disability at an accelerated rate, typically reaching Expanded Di..

The histopathological staging of tau, but not amyloid, corresponds to antemortem cognitive status, dementia stage, functional abilities and neuropsychiatric symptoms

Charles B Malpas, Sifat Sharmin, Tomas Kalincik

Journal article  |  2020  |  International Journal of Neuroscience

Purpose: Alzheimer's disease (AD) is characterised by two cardinal pathologies, namely the extracellular accumulation amyloid-rela..

Timing of high-efficacy therapy for multiple sclerosis: a retrospective observational cohort study

Anna He, Bernd Merkel, James William L Brown, Lana Zhovits Ryerson, Ilya Kister, Charles B Malpas, Sifat Sharmin, Dana Horakova, Eva Kubala Havrdova, Tim Spelman, Guillermo Izquierdo, Sara Eichau, Maria Trojano, Alessandra Lugaresi, Raymond Hupperts, Patrizia Sola, Diana Ferraro, Jan Lycke, Francois Grand'Maison, Alexandre Prat, et al.

Journal article  |  2020  |  The Lancet Neurology

BACKGROUND: High-efficacy therapies in multiple sclerosis are traditionally used after unsuccessful treatment with first-line dise..

The histopathological staging of tau, but not amyloid, corresponds to antemortem cognitive status, dementia stage, functional abilities, and neuropsychiatric symptoms

Charles Malpas, Sifat Sharmin, Tomas Kalincik

Journal article  |  2019

Abstract Objective Alzheimer’s disease (AD) is characterised by two cardinal pathologies, namely the extracellular accumulation am..

Orthostatic hypotension and cognition in older adults: A systematic review and meta-analysis

Rebecca Iseli, Truc Vo Nguyen Vi, Sifat Sharmin, Esmee M Reijnierse, Wen Kwang Lim, Andrea B Maier

Journal article  |  2019  |  Experimental Gerontology

Orthostatic Hypotension and Falls in Older Adults: A Systematic Review and Meta-analysis

Arjen Mol, Thanh Silvie Bui Hoang Phuong, Sifat Sharmin, Esmee M Reijnierse, Richard JA van Wezel, Carel GM Meskers, Andrea B Maier

Journal article  |  2019  |  JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION