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IL-23 costimulates antigen-specific MAIT cell activation and enables vaccination against b..
IL-23 co-stimulation drives antigen-specific MAIT cell activation and enables vaccination ..
Displaying the 5 most recent scholarly works by Xin Yi Lim.
The molecular basis underpinning the potency and specificity of MAIT cell antigens
Wael Awad, Geraldine JM Ler, Weijun Xu, Andrew N Keller, Jeffrey YW Mak, Xin Yi Lim, Ligong Liu, Sidonia BG Eckle, Jerome Le Nours, James McCluskey, Alexandra J Corbett, David P Fairlie, Jamie Rossjohn
Journal article | 2020 | Nature Immunology
Mucosal-associated invariant T (MAIT) cells are activated by microbial riboflavin-based metabolite antigens when presented by MR1...
IL-23 costimulates antigen-specific MAIT cell activation and enables vaccination against bacterial infection
Huimeng Wang, Lars Kjer-Nielsen, Mai Shi, Criselle D'Souza, Troi J Pediongco, Hanwei Cao, Lyudmila Kostenko, Xin Yi Lim, Sidonia BG Eckle, Bronwyn S Meehan, Tianyuan Zhu, Bingjie Wang, Zhe Zhao, Jeffrey YW Mak, David P Fairlie, Michele WL Teng, Jamie Rossjohn, Di Yu, Barbara Fazekas de St Groth, George Lovrecz, et al.
Journal article | 2019 | Science Immunology
Mucosal-associated invariant T (MAIT) cells are activated in a TCR-dependent manner by antigens derived from the riboflavin synthe..
IL-23 co-stimulation drives antigen-specific MAIT cell activation and enables vaccination against bacterial infection
H Wang, L Kjer-Nielsen, M Shi, DC Souza, T Pediongco, H Cao, L Kostenko, X Lim, S Eckle, B Meeha, B Wang, T Zhu, J Mak, D Fairlie, M Teng, J Rossjohn, D Yu, B Groth, J McCluskey, R Strugnell, et al.
Conference Proceedings | 2019 | EUROPEAN JOURNAL OF IMMUNOLOGY
MAIT cells protect against pulmonary Legionella longbeachae infection
Huimeng Wang, Criselle D'Souza, Xin Yi Lim, Lyudmila Kostenko, Troi J Pediongco, Sidonia BG Eckle, Bronwyn S Meehan, Mai Shi, Nancy Wang, Shihan Li, Ligong Liu, Jeffrey YW Mak, David P Fairlie, Yoichiro Iwakura, Jennifer M Gunnersen, Andrew W Stent, Dale I Godfrey, Jamie Rossjohn, Glen P Westall, Lars Kjer-Nielsen, et al.
Journal article | 2018 | NATURE COMMUNICATIONS
Priming programed Mucosal-Associated Invariant T cells protect against systemic or local bacterial infection
Zhe Zhao, Mai Shi, Tianyuan Zhu, Huimeng Wang, Troi Pediongco, Xin Yi Lim, Bronwyn Meehan, Adam Nelson, David Fairlie, Jeffrey Mak, Sidonia Eckle, Jamie Rossjohn, James McCluskey, Alexandra Corbett, Zhenjun Chen
Abstract Mucosal-Associated Invariant T (MAIT) cells have potent antibacterial functions. Their protective capacity, in vi..