Audrey Chan

Bone Geometry Is Altered by Follistatin-Induced Muscle Growth in Young Adult Male Mice.

Audrey SM Chan, Narelle E McGregor, Ingrid J Poulton, Justin P Hardee, Ellie H-J Cho, T John Martin, Paul Gregorevic, Natalie A Sims, Gordon S Lynch

Journal article  |  2021  |  JBMR Plus

The development of the musculoskeletal system and its maintenance depends on the reciprocal relationship between muscle and bone. ..

Brief exposure to full length parathyroid hormone-related protein (PTHrP) causes persistent generation of cyclic AMP through an endocytosis-dependent mechanism

Patricia WM Ho, Audrey S Chan, Nathan J Pavlos, Natalie A Sims, T John Martin

Journal article  |  2019  |  BIOCHEMICAL PHARMACOLOGY

Parathyroid hormone (PTH)-related protein (PTHrP) (gene name Pthlh) was discovered as the factor responsible for the humoral hyper..

Parathyroid Hormone-Related Protein Negatively Regulates Tumor Cell Dormancy Genes in a PTHR1/Cyclic AMP-Independent Manner

Rachelle W Johnson, Yao Sun, Patricia WM Ho, Audrey SM Chan, Jasmine A Johnson, Nathan J Pavlos, Natalie A Sims, T John Martin

Journal article  |  2018  |  FRONTIERS IN ENDOCRINOLOGY

Parathyroid hormone-related protein (PTHrP) expression in breast cancer is enriched in bone metastases compared to primary tumors...

A molecular code for endosomal recycling of phosphorylated cargos by the SNX27-retromer complex.

Thomas Clairfeuille, Caroline Mas, Audrey SM Chan, Zhe Yang, Maria Tello-Lafoz, Mintu Chandra, Jocelyn Widagdo, Markus C Kerr, Blessy Paul, Isabel Mérida, Rohan D Teasdale, Nathan J Pavlos, Victor Anggono, Brett M Collins

Journal article  |  2016  |  Nat Struct Mol Biol

Recycling of internalized receptors from endosomal compartments is essential for the receptors' cell-surface homeostasis. Sorting ..

Mutations of Vasopressin Receptor 2 Including Novel L312S Have Differential Effects on Trafficking.

Anatoly Tiulpakov, Carl W White, Rekhati S Abhayawardana, Heng B See, Audrey S Chan, Ruth M Seeber, Julian I Heng, Ivan Dedov, Nathan J Pavlos, Kevin DG Pfleger

Journal article  |  2016  |  Mol Endocrinol

Nephrogenic syndrome of inappropriate antidiuresis (NSIAD) is a genetic disease first described in 2 unrelated male infants with s..

Sorting nexin 27 couples PTHR trafficking to retromer for signal regulation in osteoblasts during bone growth.

Audrey SM Chan, Thomas Clairfeuille, Euphemie Landao-Bassonga, Genevieve Kinna, Pei Ying Ng, Li Shen Loo, Tak Sum Cheng, Minghao Zheng, Wanjin Hong, Rohan D Teasdale, Brett M Collins, Nathan J Pavlos

Journal article  |  2016  |  Mol Biol Cell

The parathyroid hormone 1 receptor (PTHR) is central to the process of bone formation and remodeling. PTHR signaling requires rece..