Kanta Subbarao

Predicting the efficacy of variant-modified COVID-19 vaccine boosters

David S Khoury, Steffen S Docken, Kanta Subbarao, Stephen J Kent, Miles P Davenport, Deborah Cromer

Journal article  |  2023  |  NATURE MEDICINE

Booster vaccination for the prevention of Coronavirus Disease 2019 (COVID-19) is required to overcome loss of protection due to wa..

When to update COVID-19 vaccine composition

Rebecca Grant, Jilian A Sacks, Priya Abraham, Supamit Chunsuttiwat, Cheryl Cohen, J Peter Figueroa, Thomas Fleming, Paul Fine, David Goldblatt, Hideki Hasegawa, C Raina MacIntrye, Ziad A Memish, Elizabeth Miller, Sergio Nishioka, Amadou A Sall, Samba Sow, Oyewale Tomori, Youchun Wang, Maria D Van Kerkhove, Marie-Ange Wambo, et al.

Journal article  |  2023  |  NATURE MEDICINE

Correlates of Protection, Thresholds of Protection, and Immunobridging among Persons with SARS-CoV-2 Infection.

David S Khoury, Timothy E Schlub, Deborah Cromer, Megan Steain, Youyi Fong, Peter B Gilbert, Kanta Subbarao, James A Triccas, Stephen J Kent, Miles P Davenport

Journal article  |  2023  |  Emerg Infect Dis

Several studies have shown that neutralizing antibody levels correlate with immune protection from COVID-19 and have estimated the..

Fc engineered ACE2-Fc is a potent multifunctional agent targeting SARS-CoV2 (vol 13, 889372, 2022)

Bruce D Wines, Liriye Kurtovic, Halina M Trist, Sandra Esparon, Ester Lopez, Klasina Chappin, Li-Jin Chan, Francesca L Mordant, Wen Shi Lee, Nicholas A Gherardin, Sheila K Patel, Gemma E Hartley, Phillip Pymm, James P Cooney, James G Beeson, Dale I Godfrey, Louise M Burrell, Menno C van Zelm, Adam K Wheatley, Amy WW Chung, et al.

Journal article  |  2023  |  FRONTIERS IN IMMUNOLOGY

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Age-related differences in SARS-CoV-2 binding factors: An explanation for reduced susceptibility to severe COVID-19 among children?

Thomas Abrehart, Randy Suryadinata, Conor McCafferty, Jonathan Jacobson, Vera Ignjatovic, Phil Robinson, Nigel W Crawford, Paul Monagle, Kanta Subbarao, Catherine Satzke, Danielle Wurzel

Journal article  |  2022  |  PAEDIATRIC RESPIRATORY REVIEWS

CONTEXT: In contrast with other respiratory viruses, children infected with SARS-CoV-2 are largely spared from severe COVID-19. OB..

Heparin Inhibits SARS-CoV-2 Replication in Human Nasal Epithelial Cells

Leo Yi Yang Lee, Randy Suryadinata, Conor McCafferty, Vera Ignjatovic, Damian FJ Purcell, Phil Robinson, Craig J Morton, Michael W Parker, Gary P Anderson, Paul Monagle, Kanta Subbarao, Jessica A Neil

Journal article  |  2022  |  VIRUSES-BASEL

SARS-CoV-2 is the causative agent of the COVID-19 pandemic. Vaccination, supported by social and public health measures, has prove..

Antibody titres elicited by the 2018 seasonal inactivated influenza vaccine decline by 3 months post-vaccination but persist for at least 6 months

Francesca LL Mordant, Olivia HH Price, Rajeev Rudraraju, Monica AA Slavin, Caroline Marshall, Leon JJ Worth, Heidi Peck, Ian GG Barr, Sheena GG Sullivan, Kanta Subbarao

Journal article  |  2022  |  INFLUENZA AND OTHER RESPIRATORY VIRUSES

BACKGROUND: In Australia, seasonal inactivated influenza vaccine is typically offered in April. However, the onset, peak and end o..

SARS-CoV-2 Omicron BA.1 Challenge after Ancestral or Delta Infection in Mice

Mariana Baz, Nikita Deshpande, Charlie Mackenzie-Kludas, Francesca Mordant, Danielle Anderson, Kanta Subbarao

Journal article  |  2022  |  EMERGING INFECTIOUS DISEASES

We assessed cross-reactivity to BA.1, BA.2, and BA.5 of neutralizing antibodies elicited by ancestral, Delta, and Omicron BA.1 SAR..

Sequential Transmission of Influenza Viruses in Ferrets Does Not Enhance Infectivity and Does Not Predict Transmissibility in Humans

Troy C Sutton, Elaine W Lamirande, Devanshi R Patel, Katherine EE Johnson, Rita Czako, Elodie Ghedin, Raphael TC Lee, Sebastian Maurer-Stroh, Kanta Subbarao

Journal article  |  2022  |  MBIO

Airborne transmission in ferrets is a key component of pandemic risk assessment. However, some emerging avian influenza viruses tr..

Biparatopic nanobodies targeting the receptor binding domain efficiently neutralize SARS-CoV-2

Phillip Pymm, Samuel J Redmond, Olan Dolezal, Francesca Mordant, Ester Lopez, James P Cooney, Kathryn C Davidson, Ebene R Haycroft, Chee Wah Tan, Rebecca Seneviratna, Samantha L Grimley, Damian FJ Purcell, Stephen J Kent, Adam K Wheatley, Lin-Fa Wang, Andrew Leis, Alisa Glukhova, Marc Pellegrini, Amy W Chung, Kanta Subbarao, et al.

Journal article  |  2022  |  ISCIENCE

The development of therapeutics to prevent or treat COVID-19 remains an area of intense focus. Protein biologics, including monocl..