Wayne Crismani

Methodology for the identification of small molecule inhibitors of the Fanconi Anaemia ubiquitin E3 ligase complex

Michael F Sharp, Vince J Murphy, Sylvie Van Twest, Winnie Tan, Jennii Lui, Kaylene J Simpson, Andrew J Deans, Wayne Crismani

Journal article  |  2020  |  Scientific Reports

DNA inter-strand crosslinks (ICLs) threaten genomic stability by creating a physical barrier to DNA replication and transcription...

Preparation and purification of mono-ubiquitinated proteins using Avi-tagged ubiquitin

Winnie Tan, Vincent J Murphy, Aude Charron, Sylvie van Twest, Michael Sharp, Angelos Constantinou, Michael W Parker, Wayne Crismani, Rohan Bythell-Douglas, Andrew J Deans

Journal article  |  2020  |  PLoS One

Site-specific conjugation of ubiquitin onto a range of DNA repair proteins regulates their critical functions in the DNA damage re..