Shashank Masaldan

Cellular Senescence and Iron Dyshomeostasis in Alzheimer's Disease

Shashank Masaldan, Abdel Ali Belaidi, Scott Ayton, Ashley Bush

Journal article  |  2019  |  PHARMACEUTICALS

Iron dyshomeostasis is a feature of Alzheimer's disease (AD). The impact of iron on AD is attributed to its interactions with the ..

Striking while the iron is hot: Iron metabolism and ferroptosis in neurodegeneration

Shashank Masaldan, Ashley I Bush, David Devos, Anne Sophie Rolland, Caroline Moreau

Journal article  |  2019  |  FREE RADICAL BIOLOGY AND MEDICINE

Redox active metals in neurodegenerative diseases

Karla Acevedo, Shashank Masaldan, Carlos M Opazo, Ashley I Bush

Journal article  |  2019  |  JBIC Journal of Biological Inorganic Chemistry

Copper (Cu) and iron (Fe) are redox active metals essential for the regulation of cellular pathways that are fundamental for brain..

Copper accumulation in senescent cells: Interplay between copper transporters and impaired autophagy

Shashank Masaldan, Shamel AS Clatworthy, Cristina Gamell, Zoe M Smith, Paul S Francis, Delphine Denoyer, Peter M Meggyesy, Sharon La Fontaine, Michael A Cater

Journal article  |  2018  |  Redox Biology

Iron accumulation in senescent cells is coupled with impaired ferritinophagy and inhibition of ferroptosis

Shashank Masaldan, Sharnel AS Clatworthy, Cristina Gamell, Peter M Meggyesy, Antonia-Tonia Rigopoulos, Sue Haupt, Ygal Haupt, Delphine Denoyer, Paul A Adlard, Ashley I Bush, Michael A Cater

Journal article  |  2018  |  REDOX BIOLOGY