Aung Aung Kywe Moe

Jugular vagal ganglia neurons and airway nociception: A target for treating chronic cough

Aung Aung Kywe Moe, Alice E McGovern, Stuart B Mazzone

Journal article  |  2021  |  INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The airways receive a dense supply of sensory nerve fibers that are responsive to damaging or potentially injurious stimuli. These..

A Role of the Nervous System in Modulating Respiratory Viral Infections

AE Mcgovern, N Verzele, B Chua, C Law, M Ritchie, A Moe, K Chew, SB Mazzone, K Short

Conference Proceedings  |  2021  |  AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The impact of influenza pulmonary infection and inflammation on vagal bronchopulmonary sensory neurons

Nathalie AJ Verzele, Brendon Y Chua, Charity W Law, Albert Zhang, Matthew E Ritchie, Oliver Wightman, Isaac N Edwards, Katina D Hulme, Conor J Bloxham, Helle Bielefeldt-Ohmann, Matthew W Trewella, Aung Aung Kywe Moe, Keng Yih Chew, Stuart B Mazzone, Kirsty R Short, Alice E McGovern

Journal article  |  2021  |  FASEB JOURNAL

Influenza A virus (IAV) is rapidly detected in the airways by the immune system, with resident parenchymal cells and leukocytes or..

Mini Review: Central Organization of Airway Afferent Nerve Circuits

Robert Behrens, Alice E McGovern, Michael J Farrell, Aung Aung Kywe Moe, Stuart B Mazzone

Journal article  |  2021  |  NEUROSCIENCE LETTERS

Airway afferents monitor the local chemical and physical micro-environments in the airway wall and lungs and send this information..

Dysfunction in nonsense-mediated decay, protein homeostasis, mitochondrial function, and brain connectivity in ALS-FUS mice with cognitive deficits

Wan Yun Ho, Ira Agrawal, Sheue-Houy Tyan, Emma Sanford, Wei-Tang Chang, Kenneth Lim, Jolynn Ong, Bernice Siu Yan Tan, Aung Aung Kywe Moe, Regina Yu, Peiyan Wong, Greg Tucker-Kellogg, Edward Koo, Kai-Hsiang Chuang, Shuo-Chien Ling

Journal article  |  2021  |  ACTA NEUROPATHOLOGICA COMMUNICATIONS

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) represent two ends of the same disease spectrum of adult-ons..

Peripheral and central mechanisms of cough hypersensitivity

Nabita Singh, Alexandria K Driessen, Alice E McGovern, Aung Aung Kywe Moe, Michael J Farrell, Stuart B Mazzone

Journal article  |  2020  |  JOURNAL OF THORACIC DISEASE

Chronic cough is a difficult to treat symptom of many respiratory and some non-respiratory diseases, indicating that varied pathol..

A role for neurokinin 1 receptor expressing neurons in the paratrigeminal nucleus in bradykinin-evoked cough in guinea-pigs

Alexandria K Driessen, Alice E McGovern, Robert Behrens, Aung Aung Kywe Moe, Michael J Farrell, Stuart B Mazzone

Journal article  |  2020  |  JOURNAL OF PHYSIOLOGY-LONDON

KEY POINTS: Airway projecting sensory neurons arising from the jugular vagal ganglia terminate centrally in the brainstem paratrig..

Transcriptional Profiling of Individual Airway Projecting Vagal Sensory Neurons

Stuart B Mazzone, Luyi Tian, Aung Aung Kywe Moe, Matthew W Trewella, Matthew E Ritchie, Alice E McGovern

Journal article  |  2019  |  MOLECULAR NEUROBIOLOGY

Bronchopulmonary sensory neurons are derived from the vagal sensory ganglia and are essential for monitoring the physical and chem..

Translational review: Neuroimmune mechanisms in cough and emerging therapeutic targets

Alice E McGovern, Kirsty R Short, Aung Aung Kywe Moe, Stuart B Mazzone

Journal article  |  2018  |  JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Cough is an essential defensive behavior for maintaining airway patency and to protect the lungs from potentially harmful agents. ..

Short- and long-term effects of risperidone on catalepsy sensitisation and acquisition of conditioned avoidance response: Adolescent vs adult rats

Aung Aung Kywe Moe, Gregory A Medely, Timothy Reeks, Thomas HJ Burne, Darryl W Eyles

Journal article  |  2017  |  PHARMACOLOGICAL RESEARCH

The effects of antipsychotic drugs (APDs) on the adolescent brain are poorly understood despite a dramatic increase in prescriptio..