Vinzenz Hofferek

The impact of antibacterial peptides on bacterial lipid membranes depends on stage of growth

Tzong-Hsien Lee, Vinzenz Hofferek, Marc-Antoine Sani, Frances Separovic, Gavin E Reid, Marie-Isabel Aguilar

Journal article  |  2021  |  FARADAY DISCUSSIONS

The impact of maculatin 1.1 (Mac1) on the mechanical properties of supported lipid membranes derived from exponential growth phase..

Chemical Derivatization-Aided High Resolution Mass Spectrometry for Shotgun Lipidome Analysis

Vinzenz Hofferek, Huaqi Su, Gavin E Reid

Journal article  |  2021  |  MASS SPECTROMETRY-BASED LIPIDOMICS

Chemical derivatization coupled with nano-electrospray ionization (nESI) and ultra-high resolution accurate mass spectrometry (UHR..

Cardiolipin is required for membrane docking of mitochondrial ribosomes and protein synthesis

Richard G Lee, Junjie Gao, Stefan J Siira, Anne-Marie Shearwood, Judith A Ermer, Vinzenz Hofferek, James C Mathews, Minghao Zheng, Gavin E Reid, Oliver Rackham, Aleksandra Filipovska

Journal article  |  2020  |  JOURNAL OF CELL SCIENCE

The mitochondrial inner membrane contains a unique phospholipid known as cardiolipin (CL), which stabilises the protein complexes ..

Solid-State NMR Study of Live Bacteria in the Presence of Antimicrobial Agents

Shiying Zhu, Sarah A Overall, Vinzenz Hofferek, Frances Separovic, Marc-Antoine Sani

Conference Proceedings  |  2020  |  BIOPHYSICAL JOURNAL

The role of bacterial lipid diversity and membrane properties in modulating antimicrobial peptide activity and drug resistance

Tzong-Hsien Lee, Vinzenz Hofferek, Frances Separovic, Gavin E Reid, Marie-Isabel Aguilar

Journal article  |  2019  |  CURRENT OPINION IN CHEMICAL BIOLOGY

This review provides an analysis of the role that membrane composition and structure plays in the resistance of microorganisms to ..

Nitroxide spin-labeled peptides for DNP-NMR in-cell studies

Marc-Antoine Sani, Shiying Zhu, Vinzenz Hofferek, Frances Separovic

Journal article  |  2019  |  FASEB JOURNAL

Antimicrobial peptides (AMPs) that target lipid membranes show promise as alternatives to conventional antibiotics. However, the m..

The α/β-hydrolase domain-containing 4- and 5-related phospholipase Pummelig controls energy storage in Drosophila.

Philip Hehlert, Vinzenz Hofferek, Christoph Heier, Thomas O Eichmann, Dietmar Riedel, Jonathan Rosenberg, Anna Takaćs, Harald M Nagy, Monika Oberer, Robert Zimmermann, Ronald P Kühnlein

Journal article  |  2019  |  J Lipid Res

Triglycerides (TGs) are the main energy storage form that accommodates changing organismal energy demands. In Drosophila melanogas..

A Non-canonical Pathway with Potential for Safer Modulation of Transforming Growth Factor-beta 1 in Steroid-Resistant Airway Diseases

Meina Li, Christine R Keenan, Guillermo Lopez-Campos, Jonathan E Mangum, Qianyu Chen, Danica Prodanovic, Yuxiu C Xia, Shenna Y Langenbach, Trudi Harris, Vinzenz Hofferek, Gavin E Reid, Alastair G Stewart

Journal article  |  2019  |  ISCIENCE

Impaired therapeutic responses to anti-inflammatory glucocorticoids (GC) in chronic respiratory diseases are partly attributable t..

MiR171h restricts root symbioses and shows like its target NSP2 a complex transcriptional regulation in Medicago truncatula

Vinzenz Hofferek, Amelie Mendrinna, Nicole Gaude, Franziska Krajinski, Emanuel A Devers

Journal article  |  2014  |  BMC PLANT BIOLOGY

BACKGROUND: Legumes have the unique capability to undergo root nodule and arbuscular mycorrhizal symbiosis. Both types of root end..