Gerald Murray

A custom amplicon sequencing approach to detect resistance associated mutations and sequence types in Mycoplasma genitalium.

EL Plummer, GL Murray, K Bodiyabadu, J Su, SM Garland, CS Bradshaw, TRH Read, SN Tabrizi, JA Danielewski

Journal article  |  2020  |  Journal of Microbiological Methods

BACKGROUND: Mycoplasma genitalium resistance to antibiotic treatments is increasing, with very limited treatment alternatives on t..

Correction: Leptospiral LPS escapes mouse TLR4 internalization and TRIF-associated antimicrobial responses through O antigen and associated lipoproteins.

Delphine Bonhomme, Ignacio Santecchia, Frédérique Vernel-Pauillac, Martine Caroff, Pierre Germon, Gerald Murray, Ben Adler, Ivo G Boneca, Catherine Werts

Journal article  |  2020  |  PLOS Pathogens

[This corrects the article DOI: 10.1371/journal.ppat.1008639.].

Evaluation of ResistancePlus MG FleXible, a 'near-patient' test for the detection of Mycoplasma genitalium and macrolide resistance mutations, using freshly collected clinical samples.

Gerald L Murray, Michelle Doyle, Kaveesha Bodiyabadu, Lenka A Vodstrcil, Suzanne M Garland, Jennifer Danielewski, Dorothy A Machalek, Colette McGuinness, Erica L Plummer, Vesna De Petra, Deborah A Williamson, Catriona S Bradshaw

Journal article  |  2020  |  Journal of Medical Microbiology

Introduction.Mycoplasma genitalium is a sexually transmitted pathogen with increasing resistance to first- and second-line antimic..

Treating male partners of women with bacterial vaginosis (StepUp): a protocol for a randomised controlled trial to assess the clinical effectiveness of male partner treatment for reducing the risk of BV recurrence.

Lenka A Vodstrcil, Erica L Plummer, Michelle Doyle, Christopher K Fairley, Colette McGuiness, Deborah Bateson, Jane S Hocking, Matthew G Law, Kathy Petoumenos, Basil Donovan, Eric PF Chow, Catriona S Bradshaw, undefined StepUp RCT Team

Journal article  |  2020  |  BMC Infectious Diseases

BACKGROUND: Bacterial vaginosis (BV) is estimated to affect 1 in 3 women globally and is associated with obstetric and gynaecologi..

Prevalence of mutations associated with resistance to macrolides and fluoroquinolones in Mycoplasma genitalium: a systematic review and meta-analysis

Dorothy A Machalek, Yusha Tao, Hannah Shilling, Jorgen S Jensen, Magnus Unemo, Gerald Murray, Eric PF Chow, Nicola Low, Suzanne M Garland, Lenka A Vodstrcil, Christopher K Fairley, Jane S Hocking, Lei Zhang, Catriona S Bradshaw

Journal article  |  2020  |  The Lancet Infectious Diseases

BACKGROUND: Mycoplasma genitalium is now recognised as an important bacterial sexually transmitted infection. We summarised data f..

Resistance-Guided Antimicrobial Therapy Using Doxycycline-Moxifloxacin and Doxycycline-2.5 g Azithromycin for the Treatment of Mycoplasma genitalium Infection: Efficacy and Tolerability.

Duygu Durukan, Tim RH Read, Gerald Murray, Michelle Doyle, Eric PF Chow, Lenka A Vodstrcil, Christopher K Fairley, Ivette Aguirre, Elisa Mokany, Lit Y Tan, Marcus Y Chen, Catriona S Bradshaw

Journal article  |  2020  |  Clinical Infectious Diseases

BACKGROUND: Macrolide resistance in Mycoplasma genitalium (MG) exceeds 50% in many regions, and quinolone resistance is increasing..

hTERT Protein Expression in Cytoplasm and Nucleus and its Association With HPV Infection in Patients With Cervical Cancer

Pablo Moreno-Acosta, MOnica Molano, Nicolas Morales, Jinneth Acosta, Cristian Gonzalez-Prieto, Diana Mayorga, Lina Buitrago, Oscar Gamboa, Juan Carlos Mejia, July Castro, Alfredo Romero-Rojas, Sophie Espenel, Gerald L Murray, Suzanne M Garland, Alexis Vallard, Nicolas Magne

Journal article  |  2020  |  Cancer Genomics and Proteomics

BACKGROUND: Few studies have analyzed the association between human telomerase reverse transcriptase (hTERT) protein expression (n..

Sex is associated with the persistence of non-optimal vaginal microbiota following treatment for bacterial vaginosis: a prospective cohort study

LK Ratten, EL Plummer, GL Murray, J Danielewski, CK Fairley, SM Garland, JS Hocking, G Tachedjian, EPF Chow, CS Bradshaw, LA Vodstrcil

Journal article  |  2020  |  BJOG An International Journal of Obstetrics & Gynaecology

Leptospiral LPS escapes mouse TLR4 internalization and TRIF‑associated antimicrobial responses through O antigen and associated lipoproteins.

Delphine Bonhomme, Ignacio Santecchia, Frédérique Vernel-Pauillac, Martine Caroff, Pierre Germon, Gerald Murray, Ben Adler, Ivo G Boneca, Catherine Werts

Journal article  |  2020  |  PLoS Pathogens

Leptospirosis is a worldwide re-emerging zoonosis caused by pathogenic Leptospira spp. All vertebrate species can be infected; hum..

Doxycycline and Sitafloxacin Combination Therapy for Treating Highly Resistant Mycoplasma genitalium

Duygu Durukan, Michelle Doyle, Gerald Murray, Kaveesha Bodiyabadu, Lenka Vodstrcil, Eric PF Chow, Jorgen S Jensen, Christopher K Fairley, Ivette Aguirre, Catriona S Bradshaw

Journal article  |  2020  |  Emerging Infectious Diseases

Antimicrobial-resistant Mycoplasma genitalium is becoming increasingly common and creating major treatment challenges. We present ..