Shakira Milton

The CRISP Trial: RCT of a decision support tool for risk-stratified colorectal cancer screening

Jon Emery, Mark A Jenkins, Sibel Saya, Patty Chondros, Jasmeen Oberoi, Shakira Milton, Kitty Novy, Emily Habgood, Napin Karnchanachari, Marie Pirotta, Lyndal Trevena, Adrian Bickerstaffe, Richard de Abreu Lourenco, Crothers Anna, Driss Ait Ouakrim, Louisa Flander, James G Dowty, Fiona M Walter, Malcolm Clark, Sally Doncovio, et al.

Journal article  |  2023  |  British Journal of General Practice

Background: A risk-stratified approach to colorectal cancer (CRC) screening could result in more acceptable balance of benefits an..

The nature and impact of patient and public involvement in cancer prevention, screening and early detection research: A systematic review

Rebecca J Bergin, Camille E Short, Nikki Davis, Julie Marker, Maria Teresa Dawson, Shakira Milton, Mairead McNamara, Paige Druce, Kristi Milley, Napin Karnchanachari, Gemma Skaczkowski

Journal article  |  2023  |  PREVENTIVE MEDICINE

Patient and public involvement can produce high-quality, relevant research that better addresses the needs of patients and their f..

The SCRIPT trial: study protocol for a randomised controlled trial of a polygenic risk score to tailor colorectal cancer screening in primary care

Sibel Saya, Lucy Boyd, Patty Chondros, Mairead McNamara, Michelle King, Shakira Milton, Richard De Abreu Lourenco, Malcolm Clark, George Fishman, Julie Marker, Cheri Ostroff, Richard Allman, Fiona M Walter, Daniel Buchanan, Ingrid Winship, Jennifer McIntosh, Finlay Macrae, Mark Jenkins, Jon Emery

Journal article  |  2022  |  TRIALS

BACKGROUND: Polygenic risk scores (PRSs) can predict the risk of colorectal cancer (CRC) and target screening more precisely than ..

2'-O-(N-(Aminoethyl)carbamoyl)methyl Modification Allows for Lower Phosphorothioate Content in Splice-Switching Oligonucleotides with Retained Activity.

Dmytro Honcharenko, Cristina SJ Rocha, Karin E Lundin, Jyotirmoy Maity, Stefan Milton, Ulf Tedebark, Merita Murtola, Malgorzata Honcharenko, Andis Slaitas, CI Edvard Smith, Rula Zain, Roger Strömberg

Journal article  |  2022  |  Nucleic Acid Ther

2'-O-(N-(Aminoethyl)carbamoyl)methyl (2'-O-AECM)-modified oligonucleotides (ONs) and their mixmers with 2'-O-methyl oligonucleotid..

Designing a decision aid for cancer prevention.

Shakira R Milton, Finlay Macrae, Jennifer McIntosh, Sibel Saya, Jon D Emery

Journal article  |  2022  |  Journal of Clinical Oncology

10531 Background: Australian guidelines recommend those aged 50 to 70-years-old without contraindications, consider taking low-do..

Phase I study combining pembrolizumab and aromatase inhibitor in patients with metastatic hormone receptor–positive breast cancer.

Xuan Ge, Susan Elaine Yost, Jin Sun Lee, Paul Henry Frankel, Christopher Ruel, Yujie Cui, Mireya Murga, Aileen Tang, Norma Martinez, Samuel Chung, Christina Haeyoung Yeon, Daphne B Stewart, Daneng Li, Swapnil Padmakar Rajurkar, George Somlo, Joanne E Mortimer, James Ross Waisman, Yuan Yuan

Journal article  |  2022  |  Journal of Clinical Oncology

1053 Background: Aromatase inhibitor (AI) is standard of care for patients with hormone receptor positive (HR+) human epidermal g..

Designing a decision aid for cancer prevention.

Shakira R Milton, Finlay Macrae, Jennifer McIntosh, Sibel Saya, Jon D Emery

Conference Proceedings  |  2022  |  JOURNAL OF CLINICAL ONCOLOGY

Exploring a novel method for optimising the implementation of a colorectal cancer risk prediction tool into primary care: a qualitative study

Shakira Milton, Jon D Emery, Jane Rinaldi, Joanne Kinder, Adrian Bickerstaffe, Sibel Saya, Mark A Jenkins, Jennifer McIntosh

Journal article  |  2022  |  IMPLEMENTATION SCIENCE

BACKGROUND: We developed a colorectal cancer risk prediction tool ('CRISP') to provide individualised risk-based advice for colore..

The SYMPTOM-upper gastrointestinal study: A mixed methods study exploring symptom appraisal and help-seeking in Australian upper gastrointestinal cancer patients

Napin Karnchanachari, Shakira Milton, Tjuntu Muhlen-Schulte, Riati Scarborough, Jennifer F Holland, Fiona M Walter, John Zalcberg, Jon Emery

Journal article  |  2022  |  EUROPEAN JOURNAL OF CANCER CARE

OBJECTIVE: There is limited evidence on the development of pancreatic and oesophagogastric cancer, how patients decide to seek hel..

Informed choice and attitudes regarding a genomic test to predict risk of colorectal cancer in general practice

Sibel Saya, Jennifer G McIntosh, Ingrid M Winship, Shakira Milton, Mark Clendenning, Mary Kyriakides, Jasmeen Oberoi, Daniel D Buchanan, Mark A Jenkins, Jon D Emery

Journal article  |  2022  |  PATIENT EDUCATION AND COUNSELING

OBJECTIVE: A genomic test to predict personal risk of colorectal cancer (CRC) that targets screening and could be feasibly impleme..