Johannes Kern

Successful management of treatment resistant nail psoriasis with tildrakizumab

Kate Simpson, Zhi Mei Low, Anne Howard, Johannes S Kern

Journal article  |  2021  |  AUSTRALASIAN JOURNAL OF DERMATOLOGY

Nail psoriasis significantly impacts quality of life and is notoriously difficult to treat. Tildrakizumab, an IL-23 inhibitor, has..

De-escalation of anti-CD20 monoclonal antibody (Rituximab) protocols in Pemphigus Vulgaris - a systematic review.

Jessica McClatchy, Tami Yap, Kendrick Koo, Johannes S Kern, Laura Scardamaglia

Journal article  |  2021  |  Expert Opin Biol Ther

Introduction: This review assesses current evidence supporting dose de-escalated rituximab therapy in pemphigus vulgaris, compared..

Mouse models for dominant dystrophic epidermolysis bullosa carrying common human point mutations recapitulate the human disease.

Blake RC Smith, Alexander Nyström, Cameron J Nowell, Ingrid Hausser, Christine Gretzmeier, Susan J Robertson, George A Varigos, Cristina Has, Johannes S Kern, Ken C Pang

Journal article  |  2021  |  Dis Model Mech

Heterozygous missense mutations in the human COL7A1 gene - coding for collagen VII - lead to the rare, dominantly inherited skin d..

Mouse models for dominant dystrophic epidermolysis bullosa carrying common human point mutations recapitulate the human disease

Blake RC Smith, Alexander Nystroem, Cameron J Nowell, Ingrid Hausser, Christine Gretzmeier, Susan J Robertson, George A Varigos, Cristina Has, Johannes S Kern, Ken C Pang

Journal article  |  2021  |  DISEASE MODELS & MECHANISMS

Heterozygous missense mutations in the human COL7A1 gene - coding for collagen VII - lead to the rare, dominantly inherited skin d..

Comparison of the EUROIMMUN Dermatology Profile ELISA to the novel BIOCHIP Mosaic 7 for the diagnosis of immunobullous skin disease

Kate Simpson, Laura Scardamaglia, Yonatan Kok, Mi Vu, Daniel Kidd, Tami Yap, Yang Tran, Johannes S Kern

Journal article  |  2021  |  AUSTRALASIAN JOURNAL OF DERMATOLOGY

BACKGROUND: The BIOCHIP is an indirect immunofluorescence diagnostic investigation which identifies multiple autoantibodies with a..

A casemix study of patients seen within an urban Aboriginal Health Service dermatology clinic over a five-year period

Crystal Williams, Jenny Hunt, Johannes S Kern, Rebecca Dunn

Journal article  |  2021  |  AUSTRALASIAN JOURNAL OF DERMATOLOGY

This is the largest study of Aboriginal and Torres Strait Islander dermatologic presentations to an urban specialist clinic within..

Proof of concept for the clinical effects of oral rilzabrutinib, the first Bruton tyrosine kinase inhibitor for pemphigus vulgaris: the phase II BELIEVE study.

DF Murrell, A Patsatsi, P Stavropoulos, S Baum, T Zeeli, JS Kern, A-V Roussaki-Schulze, R Sinclair, ID Bassukas, D Thomas, A Neale, P Arora, F Caux, VP Werth, SG Gourlay, P Joly, undefined BELIEVE trial investigators

Journal article  |  2021  |  Br J Dermatol

BACKGROUND: Bruton tyrosine kinase (BTK) inhibition targets B-cell and other non-T-cell immune cells implicated in the pathophysio..

Intraoral human herpes viruses detectable by PCR in majority of patients

Tami Yap, Shuan Khor, Jung Seo Kim, Jaeyoung Kim, Sung Yun Kim, Johannes S Kern, Raymond Martyres, George Varigos, Hiu Tat Chan, Michael J McCullough, Melissa L Thomas, Laura Scardamaglia

Journal article  |  2021  |  Oral Diseases

Objectives To identify factors which influence the intraoral prevalence of human herpes viruses (HHVs) using mucosal swabs, saliva..

Tildrakizumab in the treatment of moderate-to-severe hidradenitis suppurativa.

Yonatan Kok, Jenny Nicolopoulos, Anne Howard, George Varigos, Johannes Kern, Con Dolianitis

Journal article  |  2020  |  Australas J Dermatol

Multidisciplinary care of epidermolysis bullosa during the COVID-19 pandemic-Consensus: Recommendations by an international panel of experts.

Dedee F Murrell, Anne W Lucky, Julio C Salas-Alanis, David T Woodley, Francis Palisson, Ken Natsuga, Milos Nikolic, Mae Ramirez-Quizon, Amy S Paller, Irene Lara-Corrales, Mohammadreza Amir Barzegar, Eli Sprecher, Cristina Has, Martin Laimer, Anna L Bruckner, Asli Bilgic, Arti Nanda, Diana Purvis, Alain Hovnanian, Slobodna Murat-Sušić, et al.

Journal article  |  2020  |  J Am Acad Dermatol