David Price

Seeking an optimal dosing regimen for OZ439/DSM265 combination therapy for treating uncomplicated falciparum malaria

Saber Dini, Sophie G Zaloumis, David J Price, Nathalie Gobeau, Anne Kummel, Mohammed Cherkaoui, Joerg J Moehrle, James S McCarthy, Julie A Simpson

Journal article  |  2021  |  JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

BACKGROUND: The efficacy of artemisinin-based combination therapies (ACTs), the first-line treatments for uncomplicated falciparum..

977Mechanistic within-host modelling to fast-track the selection of new antimalarial combination therapies

Julie Simpson, Saber Dini, Sophie Zaloumis, David Price, James McCarthy, Mohammed Cherkaoui, Anne Kummel, Nathalie Gobeau

Journal article  |  2021  |  International Journal of Epidemiology

Abstract Background The efficacy of artemisinin-based combination therapies (A..

Development of an influenza pandemic decision support tool linking situational analytics to national response policy.

Freya M Shearer, Robert Moss, David J Price, Alexander E Zarebski, Peter G Ballard, Jodie McVernon, Joshua V Ross, James M McCaw

Journal article  |  2021  |  Epidemics: the journal of infectious disease dynamics

National influenza pandemic plans have evolved substantially over recent decades, as has the scientific research that underpins th..

Promoting Resilience While Mitigating Disease Transmission: An Australian COVID-19 Study

Freya M Shearer, Niamh Meagher, Katitza Marinkovic Chavez, Lauren Carpenter, Alana Pirrone, Phoebe Quinn, Eva Alisic, James M McCaw, Colin MacDougall, David J Price, Lisa Gibbs

Book Chapter  |  2021

Scabies and impetigo in Samoa: A school-based clinical and molecular epidemiological study

George Taiaroa, Ben Matalavea, Malama Tafuna'i, Jake A Lacey, David J Price, Lupeoletalalelei Isaia, Hinauri Leaupepe, Satupaitea Viali, Darren Lee, Claire L Gorrie, Deborah A Williamson, Susan Jack

Journal article  |  2021  |  LANCET REGIONAL HEALTH-WESTERN PACIFIC

Background: Common infections of the skin such as impetigo and scabies represent a large burden of disease globally, being particu..

An experimental design tool to optimize inference precision in data-driven mathematical models of bacterial infections in vivo

Myrto Vlazaki, David J Price, Olivier Restif

Journal article  |  2020  |  JOURNAL OF THE ROYAL SOCIETY INTERFACE

The management of bacterial diseases calls for a detailed knowledge about the dynamic changes in host-bacteria interactions. Biolo..

Estimation of the force of infection and infectious period of skin sores in remote Australian communities using interval-censored data

Michael J Lydeamore, Patricia T Campbell, David J Price, Yue Wu, Adrian J Marcato, Will Cuningham, Jonathan R Carapetis, Ross M Andrews, Malcolm McDonald, Jodie McVernon, Steven YC Tong, James M McCaw

Journal article  |  2020  |  PLoS Computational Biology

Prevalence of impetigo (skin sores) remains high in remote Australian Aboriginal communities, Fiji, and other areas of socio-econo..

Early analysis of the Australian COVID-19 epidemic

David J Price, Freya M Shearer, Michael T Meehan, Emma McBryde, Robert Moss, Nick Golding, Eamon J Conway, Peter Dawson, Deborah Cromer, James Wood, Sam Abbott, Jodie McVernon, James M McCaw

Journal article  |  2020  |  ELIFE

As of 1 May 2020, there had been 6808 confirmed cases of COVID-19 in Australia. Of these, 98 had died from the disease. The epidem..

A data-based mathematical modelling study to quantify the effects of ciprofloxacin and ampicillin on the within-host dynamics of Salmonella enterica during treatment and relapse

Myrto Vlazaki, Omar Rossi, David J Price, Callum McLean, Andrew J Grant, Pietro Mastroeni, Olivier Restif

Journal article  |  2020  |  JOURNAL OF THE ROYAL SOCIETY INTERFACE

Antibiotic therapy has drastically reduced the mortality and sequelae of bacterial infections. From naturally occurring to chemica..

The Australasian COVID-19 Trial (ASCOT) to assess clinical outcomes in hospitalised patients with SARS-CoV-2 infection (COVID-19) treated with lopinavir/ritonavir and/or hydroxychloroquine compared to standard of care: A structured summary of a study protocol for a randomised controlled trial

Justin T Denholm, Joshua Davis, David Paterson, Jason Roberts, Susan Morpeth, Thomas Snelling, Dominica Zentner, Megan Rees, Matthew O'Sullivan, David Price, Asha Bowen, Steven YC Tong

Journal article  |  2020  |  TRIALS

OBJECTIVES: To determine if lopinavir/ritonavir +/- hydroxychloroquine will reduce the proportion of participants who survive with..