Ximena Camacho

Preoperative opioid use and complications following total joint replacement: a protocol for a systematic review and meta-analysis.

Cade Shadbolt, Daniel Gould, Ximena Camacho, Josh Knight, Siddharth Rele, Sharmala Thuraisingam, Yuting Zhang, Michelle M Dowsey, Peter Fm Choong

Journal article  |  2020  |  BMJ Open

INTRODUCTION: Mounting evidence now indicates that preoperative opioid use is associated with an array of complications following ..

The Surgeon's Role in the Opioid Crisis: A Narrative Review and Call to Action

Cade Shadbolt, J Haxby Abbott, Ximena Camacho, Philip Clarke, L Stefan Lohmander, Tim Spelman, Eric C Sun, Jonas B Thorlund, Yuting Zhang, Michelle M Dowsey, Peter FM Choong

Journal article  |  2020  |  Frontiers in Surgery

Over the past two decades, there has been a sharp rise in the use of prescription opioids. In several countries, most notably the ..

Pilot study of the ability to probabilistically link clinical trial patients to administrative data and determine long-term outcomes.

Annette E Hay, Joseph L Pater, Elyse Corn, Lei Han, Ximena Camacho, Chris O'Callaghan, Nelson Chong, Erin N Bell, Dongsheng Tu, Craig C Earle

Journal article  |  2019  |  Clinical Trials

BACKGROUND: Clinical trials are important but extremely costly. Utilization of routinely collected administrative data may simplif..

Contralateral prophylactic mastectomy in young women with breast cancer: a population-based analysis of predictive factors and clinical impact

A Bouchard-Fortier, NN Baxter, R Sutradhar, K Fernandes, X Camacho, P Graham, ML Quan

Journal article  |  2018  |  Current Oncology

Background and Objectives: Contralateral prophylactic mastectomy (cpm) has been increasingly common among women with unilateral in..

Risk-Imaging Mismatch in Cardiac Imaging Practices for Women Receiving Systemic Therapy for Early-Stage Breast Cancer: A Population-Based Cohort Study.

Paaladinesh Thavendiranathan, Husam Abdel-Qadir, Hadas D Fischer, Ying Liu, Ximena Camacho, Eitan Amir, Peter C Austin, Douglas S Lee

Journal article  |  2018  |  Journal of Clinical Oncology

PURPOSE: To assess prechemotherapy cardiac imaging practices in relation to patients' heart failure (HF) risk. METHODS: We perform..

Access to routinely collected data for population health research: experiences in Canada and Australia

David Henry, Paulina Stehlik, Ximena Camacho, Sallie-Anne Pearson

Journal article  |  2018  |  AUSTRALIAN AND NEW ZEALAND JOURNAL OF PUBLIC HEALTH

Chinese and South Asian ethnicity, immigration status, and clinical cancer outcomes in the Ontario Cancer System.

James KR Stevenson, Matthew C Cheung, Craig C Earle, Hadas D Fischer, Ximena Camacho, Refik Saskin, Baiju R Shah, Peter C Austin, Simron Singh

Journal article  |  2018  |  Cancer

BACKGROUND: In the United States, certain minority groups have been shown to have inferior cancer outcomes compared with the white..

Uptake of Cancer Screening Tests Among Recipients of Solid Organ Transplantation

SA Acuna, R Sutradhar, X Camacho, C Daly, ME Del Giudice, SJ Kim, NN Baxter

Journal article  |  2017  |  American Journal of Transplantation

Population-based cancer screening recommendations are also suggested for solid organ transplant recipients (SOTR); however, recomm..

Impact of Immigration Status on Cancer Outcomes in Ontario, Canada.

Matthew C Cheung, Craig C Earle, Hadas D Fischer, Ximena Camacho, Ning Liu, Refik Saskin, Baiju R Shah, Peter C Austin, Simron Singh

Journal article  |  2017  |  Journal of Oncology Practice

BACKGROUND: Prior studies have documented inferior health outcomes in vulnerable populations, including racial minorities and thos..

Breast Cancer Therapy-Related Cardiac Dysfunction in Adult Women Treated in Routine Clinical Practice: A Population-Based Cohort Study.

Paaladinesh Thavendiranathan, Husam Abdel-Qadir, Hadas D Fischer, Ximena Camacho, Eitan Amir, Peter C Austin, Douglas S Lee

Journal article  |  2016  |  Journal of Clinical Oncology

PURPOSE: Most women diagnosed with breast cancer are younger than 65 years of age. Population-based studies on cancer therapy-rela..

Trends in the use and cost of antipsychotics among older adults from 2007 to 2013: a repeated cross-sectional study.

Paul D Foster, Ximena Camacho, Simone Vigod, Zhan Yao, David N Juurlink, J Michael Paterson, Muhammad M Mamdani, Diana Martins, Tara Gomes

Journal article  |  2016  |  CMAJ Open

BACKGROUND: Recently, several new atypical antipsychotic agents have been introduced in Ontario, and regulatory warnings have been..

The Characteristics of Treated Pulmonary Arterial Hypertension Patients in Ontario.

Haris M Vaid, Ximena Camacho, John T Granton, Muhammad M Mamdani, Zhan Yao, Samantha Singh, David N Juurlink, Tara Gomes

Journal article  |  2016  |  Canadian Respiratory Journal

Background. There are no Canadian prevalence studies on pulmonary arterial hypertension (PAH) to date. We described the characteri..

Generating Costing Algorithms For Oncology Drugs Using Administrative Databases.

N Mittmann, SJ Seung, SY Cheng, N Liu, X Camacho, L Maclagan, C DeAngelis, C Earle

Journal article  |  2015  |  Value in Health

Evaluating the Effectiveness of First-Time Methadone Maintenance Therapy Across Northern, Rural, and Urban Regions of Ontario, Canada.

Joseph K Eibl, Tara Gomes, Diana Martins, Ximena Camacho, David N Juurlink, Muhammad M Mamdani, Irfan A Dhalla, David C Marsh

Journal article  |  2015  |  Journal of Addiction Medicine

OBJECTIVES: Our objective was to determine the impact that a patient's geographic status has on the efficacy of first-time methado..

Once is Rarely Enough: A Population-Based Study of Reoperations after Postmastectomy Breast Reconstruction

Amanda Roberts, Nancy Baxter, Ximena Camacho, Cindy Lau, Toni Zhong

Journal article  |  2015  |  Annals of Surgical Oncology

PURPOSE: Postmastectomy breast reconstruction (PMBR) aims to surgically restore a breast mound following mastectomy. However, addi..

Public Drug Coverage and Its Impact on Triptan Use Across Canada: A Population-Based Study.

Anthony Amadio, Kathy Lee, Zhan Yao, Ximena Camacho, Sandra Knowles, Christine Lay, J Michael Paterson, Jordan Hunt, Tara Gomes, undefined Ontario Drug Policy Research Network

Journal article  |  2015  |  Headache: The Journal of Head and Face Pain

BACKGROUND: Public drug coverage for triptan medications varies across jurisdictions in Canada, which may lead to differences in u..

Safety of valproic acid in patients with chronic obstructive pulmonary disease: a population-based cohort study.

Tony Antoniou, Zhan Yao, Ximena Camacho, Muhammad M Mamdani, David N Juurlink, Tara Gomes

Journal article  |  2015  |  Pharmacoepidemiology and Drug Safety

PURPOSE: Valproic acid is an anticonvulsant that also inhibits histone deacetylase (HDAC), a property that could worsen pulmonary ..

Sex Differences in Dose Escalation and Overdose Death during Chronic Opioid Therapy: A Population-Based Cohort Study.

Eric Kaplovitch, Tara Gomes, Ximena Camacho, Irfan A Dhalla, Muhammad M Mamdani, David N Juurlink

Journal article  |  2015  |  PLOS ONE

BACKGROUND: The use of opioids for noncancer pain is widespread, and more than 16,000 die of opioid-related causes in the United S..

Professional Pharmacy Services and Patient Complexity: An Observational Study.

Teegan Aili Ignacy, Ximena Camacho, Muhammad M Mamdani, David N Juurlink, J Michael Paterson, Tara Gomes

Journal article  |  2015  |  Journal of Pharmacy & Pharmaceutical Sciences

PURPOSE: To examine the association between the provision of professional pharmacy services (PPS) and patient complexity as determ..

Neonatal opioid withdrawal and antenatal opioid prescribing.

Suzanne D Turner, Tara Gomes, Ximena Camacho, Zhan Yao, Astrid Guttmann, Muhammad M Mamdani, David N Juurlink, Irfan A Dhalla

Journal article  |  2015  |  CMAJ Open

BACKGROUND: The incidence of neonatal opioid withdrawal is increasing in both Canada and the United States. However, the degree to..

Impact of legislation and a prescription monitoring program on the prevalence of potentially inappropriate prescriptions for monitored drugs in Ontario: a time series analysis.

Tara Gomes, David Juurlink, Zhan Yao, Ximena Camacho, J Michael Paterson, Samantha Singh, Irfan Dhalla, Beth Sproule, Muhammad Mamdani

Journal article  |  2014  |  CMAJ Open

BACKGROUND: The increased use of opioid analgesics, sedative hypnotics and stimulants, coupled with the associated risks of overdo..

The Ontario Drug Policy Research Network: bridging the gap between Research and Drug Policy.

Sobia Khan, Julia E Moore, Tara Gomes, Ximena Camacho, Judy Tran, Glenn McAuley, David N Juurlink, Michael Paterson, Andreas Laupacis, Muhammad M Mamdani

Journal article  |  2014  |  Health Policy

Policymakers have cited several barriers to using evidence in policy decisions, including lack of research relevance and timelines..

Adherence to prescribing recommendations made on a provincial formulary.

Ainslie M Hildebrand, Zhan Yao, Tara Gomes, Ximena Camacho, Amit X Garg, David N Juurlink

Journal article  |  2014  |  Healthcare Policy | Politiques de Santé

Guidance regarding appropriate and cost-effective use of prescription drugs is published in the Ontario Drug Benefit Formulary in ..

Upper gastrointestinal bleeding in elderly adults with dementia receiving cholinesterase inhibitors: a population-based cohort study.

Kednapa Thavorn, Tara Gomes, Ximena Camacho, Zhan Yao, David Juurlink, Muhammad Mamdani

Journal article  |  2014  |  Journal of the American Geriatrics Society

Impact of the JUPITER trial on statin prescribing for primary prevention.

Jennifer FT Teng, Tara Gomes, Ximena Camacho, Scott Grundy, David N Juurlink, Muhammad M Mamdani

Journal article  |  2014  |  Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy

STUDY OBJECTIVE: As the Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER..

Comparative effectiveness of angiotensin-receptor blockers for preventing macrovascular disease in patients with diabetes: a population-based cohort study.

Tony Antoniou, Ximena Camacho, Zhan Yao, Tara Gomes, David N Juurlink, Muhammad M Mamdani

Journal article  |  2013  |  Canadian Medical Association Journal

BACKGROUND: Telmisartan, unlike other angiotensin-receptor blockers, is a partial agonist of peroxisome proliferator-activated rec..

Risk of incident diabetes among patients treated with statins: population based study.

Aleesa A Carter, Tara Gomes, Ximena Camacho, David N Juurlink, Baiju R Shah, Muhammad M Mamdani

Journal article  |  2013  |  BMJ

OBJECTIVE: To examine the risk of new onset diabetes among patients treated with different HMG-CoA reductase inhibitors (statins)...

Gender differences in home care clients and admission to long-term care in Ontario, Canada: a population-based retrospective cohort study.

Andrea Gruneir, Jacqueline Forrester, Ximena Camacho, Sudeep S Gill, Susan E Bronskill

Journal article  |  2013  |  BMC Geriatrics

BACKGROUND: Home care is integral to enabling older adults to delay or avoid long-term care (LTC) admission. To date, there is lit..

Opioid dose and risk of road trauma in Canada: a population-based study.

Tara Gomes, Donald A Redelmeier, David N Juurlink, Irfan A Dhalla, Ximena Camacho, Muhammad M Mamdani

Journal article  |  2013  |  JAMA Internal Medicine

BACKGROUND: Use of opioids may predispose drivers to road trauma, yet the effect of opioid dose on this association is unknown. ME..

Patterns and costs of health care use of children with medical complexity.

Eyal Cohen, Jay G Berry, Ximena Camacho, Geoff Anderson, Walter Wodchis, Astrid Guttmann

Journal article  |  2012  |  PEDIATRICS

BACKGROUND AND OBJECTIVE: Health care use of children with medical complexity (CMC), such as those with neurologic impairment or o..

Levothyroxine dose and risk of fractures in older adults: nested case-control study.

Marci R Turner, Ximena Camacho, Hadas D Fischer, Peter C Austin, Geoff M Anderson, Paula A Rochon, Lorraine L Lipscombe

Journal article  |  2011  |  BMJ

OBJECTIVE: To quantify the effect of levothyroxine dose on risk of fractures in older adults. DESIGN: Nested case-control study. S..

Unplanned readmissions after hospital discharge among patients identified as being at high risk for readmission using a validated predictive algorithm.

Andrea Gruneir, Irfan A Dhalla, Carl van Walraven, Hadas D Fischer, Ximena Camacho, Paula A Rochon, Geoffrey M Anderson

Journal article  |  2011  |  Open Med

BACKGROUND: Unplanned hospital readmissions are common, expensive and often preventable. Strategies designed to reduce readmission..