Piero Perucca

Economic Evaluation of the Community Benefit of the Australian Pregnancy Register of Antiseizure Medications.

Zanfina Ademi, Clara Marquina, Piero Perucca, Alison Hitchcock, Janet Graham, Mervyn J Eadie, Danny Liew, Terence J O'Brien, Frank J Vajda

Journal article  |  2023  |  Neurology

BACKGROUND AND OBJECTIVE: The Raoul Wallenberg Australian Pregnancy Register (APR) was established to collect, analyze, and publis..

Ocular motility as a measure of cerebral dysfunction in adults with focal epilepsy.

Hue Mun Au Yong, Meaghan Clough, Piero Perucca, Charles B Malpas, Patrick Kwan, Terence J O'Brien, Joanne Fielding

Journal article  |  2023  |  Epilepsy Behav

OBJECTIVE: Using objective oculomotor measures, we aimed to: (1) compare oculomotor performance in patients with drug-resistant fo..

Seizure risk in multiple sclerosis patients treated with disease-modifying therapy: A systematic review and network meta-analysis

Yew Li Dang, Vivien TY Yong, Sifat Sharmin, Piero Perucca, Tomas Kalincik

Journal article  |  2023  |  MULTIPLE SCLEROSIS JOURNAL

BACKGROUND: Multiple sclerosis patients experience 3-6 times more seizures than the general population, but observations vary amon..

EEG Datasets for Seizure Detection and Prediction - A Review.

Sheng Wong, Anj Simmons, Jessica Rivera-Villicana, Scott Barnett, Shobi Sivathamboo, Piero Perucca, Zongyuan Ge, Patrick Kwan, Levin Kuhlmann, Rajesh Vasa, Kon Mouzakis, Terence J O'Brien

Journal article  |  2023  |  Epilepsia Open

Electroencephalogram (EEG) datasets from epilepsy patients have been used to develop seizure detection and prediction algorithms u..

Cardiac structural and functional abnormalities in epilepsy: A systematic review and meta-analysis

Zining Liu, Peravina Thergarajan, Ana Antonic-Baker, Zhibin Chen, Paul B Sparks, Natasha A Lannin, Patrick Kwan, Nigel C Jones, Pablo M Casillas-Espinosa, Piero Perucca, Terence J O'Brien, Shobi Sivathamboo

Journal article  |  2023  |  EPILEPSIA OPEN

OBJECTIVE: Epilepsy is associated with an increased risk of cardiovascular disease and mortality. Whether cardiac structure and fu..

Risk of sudden unexpected death in epilepsy (SUDEP) with lamotrigine and other sodium channel-modulating antiseizure medications.

Russell Nightscales, Sarah Barnard, Juliana Laze, Zhibin Chen, Gerard Tao, Clarissa Auvrez, Shobi Sivathamboo, Mark J Cook, Patrick Kwan, Daniel Friedman, Samuel F Berkovic, Wendyl D'Souza, Piero Perucca, Orrin Devinsky, Terence J O'Brien

Journal article  |  2023  |  Epilepsia Open

OBJECTIVE: In vitro data prompted U.S Food and Drug Administration warnings that lamotrigine, a common sodium channel modulating a..

Rare Genetic Variation and Outcome of Surgery for Mesial Temporal Lobe Epilepsy

Piero Perucca, Kate Stanley, Natasha Harris, Anne M McIntosh, Ali A Asadi-Pooya, Mohamad A Mikati, Danielle M Andrade, Patricia Dugan, Chantal Depondt, Hyunmi Choi, Erin L Heinzen, Gianpiero L Cavalleri, Russell J Buono, Orrin Devinsky, Michael R Sperling, Samuel F Berkovic, Norman Delanty, David B Goldstein, Terence J O'Brien

Journal article  |  2023  |  ANNALS OF NEUROLOGY

OBJECTIVE: Genetic factors have long been debated as a cause of failure of surgery for mesial temporal lobe epilepsy (MTLE). We in..

Automated Interictal Epileptiform Discharge Detection from Scalp EEG Using Scalable Time-series Classification Approaches.

D Nhu, M Janmohamed, L Shakhatreh, O Gonen, P Perucca, A Gilligan, P Kwan, TJ O'Brien, CW Tan, L Kuhlmann

Journal article  |  2023  |  Int J Neural Syst

Deep learning for automated interictal epileptiform discharge (IED) detection has been topical with many published papers in recen..

Comorbidities in newly diagnosed epilepsy: Pre-existing health conditions are common and complex across age groups

Anne M McIntosh, Patrick W Carney, K Meng Tan, Tahir M Hakami, Piero Perucca, Patrick Kwan, Terence J O'Brien, Samuel F Berkovic

Journal article  |  2023  |  EPILEPSY & BEHAVIOR

OBJECTIVES: People with epilepsy have a higher prevalence of medical and psychiatric comorbidities compared to the general populat..

Treatment Outcomes of Newly Diagnosed Epilepsy: A Systematic Review and Meta-analysis

Mubeen Janmohamed, Haris Hakeem, Suyi Ooi, Suhailah Hakami, Lily Vu, Piero Perucca, Terence J O'Brien, Ana Antonic-Baker, Zhibin Chen, Patrick Kwan

Journal article  |  2022  |  CNS DRUGS

BACKGROUND AND OBJECTIVES: Understanding the multi-faceted treatment outcomes of newly diagnosed epilepsy is critical for developi..