Andrew Leis

Monoubiquitination by the human Fanconi anemia core complex clamps FANCI: FANCD2 on DNA in filamentous arrays

Winnie Tan, Sylvie van Twest, Andrew Leis, Rohan Bythell-Douglas, Vincent J Murphy, Michael Sharp, Michael W Parker, Wayne Crismani, Andrew J Deans

Journal article  |  2020  |  eLife

FANCI:FANCD2 monoubiquitination is a critical event for replication fork stabilization by the Fanconi anemia (FA) DNA repair pathw..

Monoubiquitination by the Fanconi Anemia core complex locks FANCI:FANCD2 on DNA in filamentous arrays

Winnie Tan, Sylvie van Twest, Andrew Leis, Rohan Bythell-Douglas, Vincent Murphy, Michael Sharp, Michael Parker, Wayne Crismani, Andrew Deans

Journal article  |  2019  |  eLife

Abstract FANCI:FANCD2 monoubiquitination is a critical event for replication fork stabilization by the Fanconi anemia (FA) DNA rep..

The structure of the PA28-20S proteasome complex from Plasmodium falciparum and implications for proteostasis

Stanley C Xie, Riley D Metcalfe, Eric Hanssen, Tuo Yang, David L Gillett, Andrew P Leis, Craig J Morton, Michael J Kuiper, Michael W Parker, Natalie J Spillman, Wilson Wong, Christopher Tsu, Lawrence R Dick, Michael DW Griffin, Leann Tilley

Journal article  |  2019  |  Nature Microbiology

The activity of the proteasome 20S catalytic core is regulated by protein complexes that bind to one or both ends. The PA28 regula..

CRYO-EM OF THE MALARIA PARASITE PA28/20S PROTEASOME COMPLEX REVEALS AN UNUSUAL ACTIVATION MECHANISM WITH IMPLICATIONS FOR ARTEMISININ SENSITIVITY

Stanley Xie, Michael Griffin, Riley Metcalfe, Eric Hanssen, Tuo Yang, David Gilley, Andrew Leis, Craig Morton, Michael Kuiper, Michael Parker, Natalie Spillman, Wilson Wong, Christopher Tsu, Lawrence Dick, Leann Tilley

Conference Proceedings  |  2019  |  PROTEIN SCIENCE

The structure of the Plasmodium falciparum 20S proteasome in complex with the PA28 activator

Riley D Metcalfe, Stanley C Xie, Eric Hanssen, Tuo Yang, David L Gillett, Andrew Leis, Craig J Morton, Michael J Kuiper, Michael W Parker, Natalie J Spillman, Wilson Wong, Christopher Tsu, Lawrence R Dick, Michael DW Griffin, Leann Tilley

Conference Proceedings  |  2019  |  Acta Crystallographica Section A: Foundations and advances

Structural Analysis of Polysaccharide Networks by Transmission Electron Microscopy: Comparison with Small-Angle X-ray Scattering

Pablo Hernandez-Cerdan, Bradley W Mansel, Andrew Leis, Leif Lundin, Martin AK Williams

Journal article  |  2018  |  Biomacromolecules

Polysaccharide gels assembled from the anionic biopolymers pectin and carrageenan have been studied using transmission electron mi..

Probing the internal and external micelle structures of differently sized casein micelles from individual cows milk by dynamic light and small-angle X-ray scattering

L Day, JK Raynes, A Leis, LH Liu, RPW Williams

Journal article  |  2017  |  Food Hydrocolloids

Casein micelles vary in size both within and between individual cows depending on the ratios of specific caseins and the level of ..

Preliminary characterization of Tasmanian aquareovirus (TSRV) isolates (vol 162, pg 625, 2017)

Sandra C Zainathan, Jeremy Carson, Mark St J Crane, Lynette M Williams, John Hoad, Nicholas JG Moody, Nicholas Gudkovs, Andrew Leis, Sandra Crameri, Alex D Hyatt, John Young, Barbara F Nowak

Journal article  |  2017  |  Archives of Virology

The published article contains incomplete author listing. The correct details got updated here. In addition, the original publicat..

Nuclear Pore-Like Structures in a Compartmentalized Bacterium

Evgeny Sagulenko, Amanda Nouwens, Richard I Webb, Kathryn Green, Benjamin Yee, Garry Morgan, Andrew Leis, Kuo-Chang Lee, Margaret K Butler, Nicholas Chia, Thi Phuong Pham Uyen, Stinus Lindgreen, Ryan Catchpole, Anthony M Poole, John A Fuerst

Journal article  |  2017  |  PLoS One

Planctomycetes are distinguished from other Bacteria by compartmentalization of cells via internal membranes, interpretation of wh..

The thermodynamics of Pr55(Gag)-RNA interaction regulate the assembly of HIV

Hanumant S Tanwar, Keith K Khoo, Megan Garvey, Lynne Waddington, Andrew Leis, Marcel Hijnen, Tony Velkov, Geoff J Dumsday, William J McKinstry, Johnson Mak

Journal article  |  2017  |  PLOS PATHOGENS

The interactions that occur during HIV Pr55Gag oligomerization and genomic RNA packaging are essential elements that facilitate HI..