Lucy Ham

Exactly solvable models of stochastic gene expression

Lucy Ham, David Schnoerr, Rowan D Brackston, Michael PH Stumpf

Journal article  |  2020  |  JOURNAL OF CHEMICAL PHYSICS

Stochastic models are key to understanding the intricate dynamics of gene expression. However, the simplest models that only accou..

Extrinsic Noise and Heavy-Tailed Laws in Gene Expression

Lucy Ham, Rowan Brackston, Michael PH Stumpf

Journal article  |  2020  |  PHYSICAL REVIEW LETTERS

Noise in gene expression is one of the hallmarks of life at the molecular scale. Here we derive analytical solutions to a set of m..

Axiomatisability and hardness for universal Horn classes of hypergraphs

L Ham, M Jackson

Journal article  |  2018  |  Algebra Universalis

We consider hypergraphs as symmetric relational structures. In this setting, we characterise finite axiomatisability for finitely ..

Relativised Homomorphism Preservation at the Finite Level

L Ham

Journal article  |  2017  |  Studia Logica

In this article, we investigate the status of the homomorphism preservation property amongst restricted classes of finite relation..

Gap theorems for robust satisfiability: Boolean CSPs and beyond

L Ham

Journal article  |  2017  |  Theoretical Computer Science

A computational problem exhibits a “gap property” when there is no tractable boundary between two disjoint sets of instances. We e..

All or nothing: Toward a promise problem dichotomy for constraint problems

L Ham, M Jackson

Conference Proceedings  |  2017  |  Principles and Practice of Constraint Programming

We show that intractability of the constraint satisfaction problem over a fixed finite constraint language can, in all known cases..

A gap trichotomy for Boolean constraint problems: Extending Schaefer's theorem

L Ham

Conference Proceedings  |  2016  |  Leibniz International Proceedings in Informatics, LIPIcs