Alesia Harper

Sulfasalazine for the treatment of preeclampsia in a nitric oxide synthase antagonist mouse model.

Natalie K Binder, Natasha de Alwis, Sally Beard, Elif Kadife, Alesia Harper, Tu'uhevaha J Kaitu'u-Lino, Fiona C Brownfoot, Natalie J Hannan

Journal article  |  2023  |  Placenta

INTRODUCTION: Development of a therapeutic that targets the pathophysiological elements of preeclampsia would be a major advance f..

SLC38A4 Amino Acid Transporter Expression Is Significantly Lower in Early Preterm Intrauterine Growth Restriction Complicated Placentas

Elif Kadife, Alesia Harper, Natasha De Alwis, Keegan Chien, Natalie Hannan, Fiona CC Brownfoot

Journal article  |  2023  |  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Intrauterine growth restriction (IUGR), predominantly caused by placental insufficiency, affects partitioning of nutrients to the ..

Associations Between Soluble fms-Like Tyrosine Kinase-1 and Placental Growth Factor and Disease Severity Among Women With Preterm Eclampsia and Preeclampsia

Roxanne Hastie, Lina Bergman, Susan P Walker, Tu'uhevaha Kaitu'u-Lino, Natalie J Hannan, Fiona Brownfoot, Sonja Schell, Alesia Harper, Ping Cannon, Catherine A Cluver, Stephen Tong

Journal article  |  2022  |  JOURNAL OF THE AMERICAN HEART ASSOCIATION

Background The angiogenic factors soluble fms-like tyrosine kinase-1 (sFlt-1) and placental growth factor (PlGF) are postulated to..

Prolonged atrazine exposure beginning in utero and adult uterine morphology in mice

Meaghan J Griffiths, Amy L Winship, Jessica M Stringer, Elyse O Swindells, Alesia P Harper, Bethany J Finger, Karla J Hutt, Mark P Green

Journal article  |  2022  |  JOURNAL OF DEVELOPMENTAL ORIGINS OF HEALTH AND DISEASE

Through drinking water, humans are commonly exposed to atrazine, a herbicide that acts as an endocrine and metabolic disruptor. It..

Hydroxychloroquine reduces soluble Flt-1 secretion from human cytotrophoblast, but does not mitigate markers of endothelial dysfunction in vitro.

Elif Kadife, Natalie Hannan, Alesia Harper, Natalie Binder, Sally Beard, Fiona C Brownfoot

Journal article  |  2022  |  PLoS One

Preeclampsia is a multi-system disease that can have severe, even fatal implications for the mother and fetus. Abnormal placentati..

P-009. Associations between circulating sFlt-1 and PlGF and preeclampsia with severe maternal complications, or eclampsia

Roxanne Hastie, Lina Bergman, Susan Walker, Tu'uhevaha Kaitu'u-Lino, Natalie Hannan, Fiona Brownfoot, Alesia Harper, Ping Cannon, Catherin Cluver, Stephen Tong

Journal article  |  2021  |  Pregnancy Hypertension

Associations between Circulating sFlt1 and PlGF and Preeclampsia with Severe Maternal Complications, or Eclampsia.

Roxanne Hastie, Lina Bergman, Susan Walker, Tu'uhevaha Kaitu'u-Lino, Natalie J Hannan, Fiona Brownfoot, Alesia Harper, Ping Cannon, Cathy A Cluver, Stephen Tong

Conference Proceedings  |  2021  |  REPRODUCTIVE SCIENCES

Nicotinamide and its effects on endothelial dysfunction and secretion of antiangiogenic factors by primary human placental cells and tissues

Fiona Brownfoot, Natalie Binder, Roxanne Hastie, Alesia Harper, Sally Beard, Laura Tuohey, Emerson Keenan, Stephen Tong, Natalie Hannan

Journal article  |  2021  |  PLACENTA

Preeclampsia is a serious pregnancy complication associated with elevated antiangiogenic markers and endothelial dysfunction. Rece..

Circulating Tissue Factor Pathway Inhibitor (TFPI) is increased preceding preeclampsia diagnosis and in established preeclampsia

Teresa M MacDonald, Stephen Tong, Jenny Myers, Ping Cannon, Nguyen Tuong-Vi, Emerson Keenan, Elizabeth Murray, Alesia Harper, Natasha Pritchard, Natalie J Hannan, Kirsten M Dane, Anna L Middleton, Valerie P Kyritsis, Susan P Walker, Tu'uhevaha J Kaitu'u-Lino

Journal article  |  2021  |  PLACENTA

INTRODUCTION: Tissue Factor Pathway Inhibitor (TFPI) is a part of the extrinsic coagulation pathway, and highly expressed in the p..

Chronic Atrazine Exposure Beginning Prenatally Impacts Liver Function and Sperm Concentration With Multi-Generational Consequences in Mice

Alesia P Harper, Bethany J Finger, Mark P Green

Journal article  |  2020  |  Frontiers in Endocrinology

Atrazine is a commonly used herbicide frequently detected in waterways and drinking water around the world. Worryingly, atrazine i..